• AI researchers argued that they could create new ontologies as computational models that enable certain kinds of automated reasoning, which was only marginally successful. (wikipedia.org)
  • There are currently more than 150 biomedical ontologies and 700,000 entities in the NCBO BioPortal http://bioportal.bioontology.org/ . (biomedcentral.com)
  • Ontologies for biologists: a community model for the annotation of genomic data. (github.io)
  • In the 1980s, the AI community began to use the term ontology to refer to both a theory of a modeled world and a component of knowledge-based systems. (wikipedia.org)
  • Application ontology for Ocular Immune-mediated Inflammatory Diseases, built from domain experts in ophthalmology, clinical guidelines, and enhanced with patient-preferred terms. (biokeanos.com)
  • The EMBL-EBI Complex Portal (www.ebi.ac.uk/intact/complex) is a central service that provides manually curated information on stable, on macromolecular complexes from model organisms. (stanford.edu)
  • The SWISS-MODEL Repository is a database of annotated 3D protein structure models generated by the SWISS-MODEL homology-modelling pipeline for protein sequences of selected model organisms. (biokeanos.com)
  • Moreover, even with the current advancements in semantic web technology, we still do not have cure for complex diseases like Alzheimer's disease. (biomedcentral.com)
  • Alzheimer's disease (AD), the most prominent neurodegenerative disease (NDD), has become a global threat to the aging society, affecting nearly 115 million people by 2050 [ 1 ]. (biomedcentral.com)
  • Neurodegenerative diseases are incurable and debilitating indications with huge social and economic impact, where much is still to be learnt about the underlying molecular events. (biomedcentral.com)
  • In this paper, we describe an approach, called as NeuroRDF , to develop an integrative framework for modeling curated knowledge in the area of complex neurodegenerative diseases. (biomedcentral.com)
  • van Loon NM , Rensen PC , Zelcer N , . IDOL in metabolic, neurodegenerative and cardiovascular disease. (impactaging.com)
  • It provides unique identifiers, names and synonyms, list of complex members with their unique identifiers (UniProt, ChEBI, RNAcentral), function, binding and stoichiometry annotations, descriptions of their topology, assembly structure, ligands and associated diseases as well as cross-references to the same complex in other databases (e.g. (stanford.edu)
  • This includes databases for large-quantity synthesis of glycogenes and glycans, analysis and detection of glycan structure and glycoprotein, glycan-related differentiation markers, glycan functions, glycan-related diseases and transgenic and knockout animals, etc. (bioregistry.io)
  • Particularly, reliable biological markers of disease and disease progression could assist in early diagnosis and treatments catered to the patient [ 5 ]. (biomedcentral.com)
  • Coronaviruses are highly infectious and pose a serious threat to human and animal healths. (bvsalud.org)
  • Follow-up assessment of phenotypic pattern over the time and clinical course was done after 3.2 ± 2.5 years at average.Results: We showed that 48% of FMD patients were prone to changes of phenotypic pattern during the disease course. (lookformedical.com)
  • The two companies have collaborated before Heska's investment, when they partnered in May to bring new point-of-care multiplex testing technology to the animal health sector. (brakkeconsulting.com)
  • Although many alternative approaches have been proposed and practiced for modeling diseases, the semantic web technology is a flexible and well established solution for harmonized aggregation. (biomedcentral.com)
  • Mechanistic disease models could offer a knowledge framework to help decipher the complex interactions that occur at molecular and cellular levels. (biomedcentral.com)
  • The aim of this study was to assess clinical features that contribute to the specific phenotypic presentations and disease course of FMD.Methods: The study consisted of 100 patients with FMD treated at Clinic for Neurology, Clinical Center of Serbia, who were longitudinally observed. (lookformedical.com)
  • This increases the probability of the derived knowledge to be novel and reliable in a specific disease context. (biomedcentral.com)
  • The most Twentieth key resources PDF that can Notify any wild P. Freeware model email, consumecontent, and resulting site. (lubs.name)
  • This motivates the need for the development of an approach integrating highly curated and heterogeneous data into a disease model of different regulatory data layers. (biomedcentral.com)
  • Although several disease models exist, they often do not consider the quality of underlying data. (biomedcentral.com)
  • Authors must be transparent about the use of Artificial Intelligence tools such as ChatGPT and other large language models in the manuscript preparation, and disclose details of how the AI tool was used within the 'Materials and Methods' section. (pensoft.net)
  • An example of economics relying on information science occurs in cases where a simulation or model is intended to enable economic decisions, such as determining what capital assets are at risk and by how much (see risk management). (wikipedia.org)