EffusionTumorsTumorEffusionsMalignancyLesionsDiagnosisGenerally benignMalignant neoplasmMesenchymal neoplasmsUsually benignRare benignCarcinomaFibromaAsbestosSoft-tissueDiseasesFibrousLymphoproliferativeCavityThoracoscopyAbnormalitiesMesotheliomaLymphaticCystsSpindle cellsDiagnosticInflammationPulmonaryBehaviorFluidClinical
Effusion11
- A pleural effusion is collection of fluid abnormally present in the pleural space, usually resulting from excess fluid production and/or decreased lymphatic absorption. (medscape.com)
- Large right-sided pleural effusion. (medscape.com)
- Left-sided pleural effusion. (medscape.com)
- disturbances in any of these mechanisms may lead to pathology and, possibly, manifest as a pleural effusion. (medscape.com)
- Presence of a pleural effusion heralds an underlying disease process that may be pulmonary or nonpulmonary in origin and, furthermore, that may be acute or chronic. (medscape.com)
- They can also present as a gastroduodenal intussusception, perforation leading to abscess formation or a unilateral pleural effusion. (sages.org)
- Pleural fluid eosinophilia is a useful finding that can aid in the diagnosis of an exudative pleural effusion. (nih.gov)
- Heterogeneous enhancement is seen and pleural effusion can be present. (eurorad.org)
- Our patient was a 69-year-old female with a large left pleural effusion. (mesothelioma-line.com)
- The Meigs' syndrome is a rare but well-known syndrome defined as the triad of benign solid ovarian tumor, ascites, and pleural effusion. (medscape.com)
- Rarely, ascites and pleural effusion accompany ovarian fibromas;this triad of findings is called Meigs syndrome. (msdmanuals.com)
Tumors22
- Gastric schwannoma represent only 0.2% of all gastric tumors and 4% of all benign gastric neoplasms. (sages.org)
- A chromosomal aberration involving CTNNB1 is found in salivary gland pleiomorphic adenomas, the most common benign epithelial tumors of the salivary gland. (enquirebio.com)
- Similar to other epithelial ovarian tumors, Benner tumors are classified as benign, borderline/atypical proliferative, or malignant. (cap.org)
- Benign Brenner tumors account for approximately 5% of all benign ovarian epithelial tumors and are typically found incidentally in women in the 5th to 7th decades of life. (cap.org)
- Brenner tumors are commonly associated with other ovarian neoplasms, including mucinous-type tumors. (cap.org)
- Grossly, benign Brenner tumors are small (typically less than 2 cm) and unilateral. (cap.org)
- Small cysts are often present, but benign Brenner tumors are rarely predominantly cystic. (cap.org)
- Borderline/atypical proliferative Brenner tumors are often larger than benign Brenner tumors, with an average diameter of 18 cm. (cap.org)
- These tumors are predominantly cystic but may contain variable solid areas, often representing a coexisting benign Brenner component. (cap.org)
- Histologically, these tumors resemble non-invasive, low-grade urothelial neoplasms. (cap.org)
- Histologically, malignant Brenner tumors are associated with a benign or borderline/atypical proliferative Brenner tumor component. (cap.org)
- A comparison of the intrathoracic malignant neurogenic tumors and the benign neurogenic tumors resected at our institution revealed no meaningful differences distinguishing malignant from benign neurogenic tumors prior to surgery. (springeropen.com)
- Additionally, we present a comparison of the clinical characteristics and outcomes of these patients and those of patients with benign neurogenic tumors (BNTs) resected at our institution. (springeropen.com)
- These slow-growing, benign fatty tumors form soft, lobulated masses enclosed by a thin, fibrous capsule. (medscape.com)
- It is more probable that lipomas are at the benign end of the spectrum of tumors, which, at the malignant end, include liposarcomas (see Pathophysiology ). (medscape.com)
- Lipomas are common benign mesenchymal tumors. (medscape.com)
- It is the most common primary intracranial neoplasm and the most diversified in histologic patterns among all primary tumors of the CNS. (medscape.com)
- Meningiomas , as defined by the World Health Organization (WHO), are "meningothelial (arachnoid) cell neoplasms, typically attached to the inner surface of the dura mater," and these tumors fall into WHO grades I, II, and III. (medscape.com)
- Benign ovarian tumors usually grow slowly and rarely become malignant. (msdmanuals.com)
- Most functional cysts and benign tumors are asymptomatic, but some cause intermittent dull or sharp pelvic pain or, infrequently, deep dyspareunia. (msdmanuals.com)
- Tumors can be benign or malignant. (medlineplus.gov)
- Benign tumors aren't cancer while malignant ones are. (medlineplus.gov)
Tumor10
- Moreover, the fibrous nature of the tumor has given rise to various other names, such as pleural fibroma, submesothelial fibroma, and localized fibrous tumor. (medscape.com)
- Pilomatrixoma (PTR) [MIM:132600]: Common benign skin tumor. (enquirebio.com)
- This case first appeared as Performance Improvement Program in Surgical Pathology (PIP) 2020, Case 31, and is benign Brenner tumor in the ovary. (cap.org)
- The findings are consistent with a benign Brenner tumor. (cap.org)
- Nests are large and crowded and may show fusion, as a result of epithelial proliferation that exceeds what is seen in benign Brenner tumor. (cap.org)
- A benign Brenner tumor component is often present in the background. (cap.org)
- Pleural mesothelioma (malignant mesothelioma) is a rare malignant tumor originating from the superficial cells of the pleural lining. (biketraffic.org)
- Such a tumor grows quickly, even leading to the growth of the entire pleural cavity. (biketraffic.org)
- This case highlights the difficulties that may be encountered in the management of patients with Meigs' syndrome, including potential misdiagnosis of the tumor as a malignant ovarian neoplasm that may influence the medical and surgical approach and the adverse impact that Meigs' syndrome can have on the patient's condition, especially if it is associated with acute pain and severe anemia. (medscape.com)
- Neurogenic tumor is a common intrathoracic neoplasm, representing approximately 20% of all adult and 35% of all pediatric mediastinal neoplasms [ 1 ]. (springeropen.com)
Effusions9
- Approximately 1.5 million pleural effusions are diagnosed in the United States each year (see images below). (medscape.com)
- Pleural effusions may result from disruption of this natural balance. (medscape.com)
- It has been stated that pleural fluid eosinophilia (defined as greater than 10 percent eosinophils in the pleural white cell differential count) is not helpful in the diagnosis of exudative effusions. (nih.gov)
- By review of the recent literature, it was found that pleural fluid eosinophilia was associated most often with idiopathic effusions or with air previously introduced into the pleural space. (nih.gov)
- Also, a high proportion of "idiopathic" and benign asbestos effusions were characterized by pleural fluid eosinophilia, a previously unrecognized phenomenon. (nih.gov)
- Estimates of pretest likelihoods of malignant versus nonmalignant pleural effusions and the prevalence of eosinophilia in effusions of known cause were obtained from extensive literature review. (nih.gov)
- Methotrexate elimination is reduced in patients with a third distribution space (ascites, pleural effusions). (medicines.org.uk)
- Ultrasonography also is useful in assessing pleural and pericardial effusions, cardiac tamponade, calcification of the pericardium, and constrictive pericarditis. (medscape.com)
- Adenocarcinomas were the most frequently diagnosed metastatic malignancies in both pleural and ascitic effusions and in both females and males. (bvsalud.org)
Malignancy3
- [ 1 ] It is the most common manifestation of pleural disease, and its etiologies range in spectrum from cardiopulmonary disorders and/or systemic inflammatory conditions to malignancy. (medscape.com)
- The presence of pleural fluid eosinophilia considerably reduced the probability of malignancy or tuberculosis and increased the likelihood of an underlying benign disorder. (nih.gov)
- Inflammatory myofibroblastic tumour (IMT) is believed to represent a benign neoplastic lesion with intermittent malignancy[1]. (eurorad.org)
Lesions10
- The mediastinum is the site for a variety of lesions, both benign and malignant. (allenpress.com)
- To investigate the use of diffusion-weighted (DW) imaging for differentiating benign lesions from malignant pleural disease (MPD) and to retrospectively assess dynamic contrast material-enhanced (DCE) magnetic resonance (MR) imaging acquisitions to find out whether combining these measurements with DW imaging could improve the diagnostic value of DW imaging. (nih.gov)
- The optimal ADC threshold to differentiate benign lesions from MPD with DW MR imaging was 1.52 × 10(-3) mm(2)/sec, with sensitivity, specificity, and accuracy of 71.4%, 100%, and 87.1%, respectively. (nih.gov)
- DW imaging is a promising tool for differentiating MPD from benign lesions, with high accuracy, and supplementation with DCE MR imaging seems to further improve sensitivity. (nih.gov)
- Immunohistochemical staining for cytokeratin 5/6 was applied on cell block sections of 23 cases of benign and 25 cases of malignant breast lesions using avidin biotin peroxidase technique. (ijpmonline.org)
- All benign lesions showed positive immunoreaction, with the staining index varying from 6-9, except lactating adenoma. (ijpmonline.org)
- The staining reaction in the malignant lesions was only cytoplasmic and the intensity was significantly less than that of benign lesions. (ijpmonline.org)
- This antibody is also used as a component of panels to differentiate benign and malignant breast lesions. (ijpmonline.org)
- IMT comprises 0.04% to 0.7% of all the lung neoplasms but in children IMT is the most common primary lung lesion accounting for 50% of all the benign lesions [3]. (eurorad.org)
- it is not easy to differentiate between benign and malignant lesions. (bvsalud.org)
Diagnosis1
- It is asymptomatic with a benign course and occurs most often in young adults, with a median age at diagnosis in the 3rd or 4th decade(3).HHV-8-associated Castleman disease is more aggressive, occurs predominantly in immunosuppressed / human immunodeficiency virus (HIV)-positive patients and manifests commonly with generalized lymphadenopathy, constitutional symptoms, and hematologic and/or immunologic abnormalities. (iriakerala.org)
Generally benign2
- The outcome after surgery is excellent as these neoplasms are generally benign in nature. (sages.org)
- Discussion Orbital SFT is a generally benign neoplasm originating from the mesenchyme, uncommon in the orbit. (scitechnol.com)
Malignant neoplasm2
- Lung cancer, or bronchogenic malignant neoplasm originating from the airway epithelium, constitutes the vast majority of lung cancers. (biketraffic.org)
- Unspecified/other malignant neoplasm of skin of upper limb, incl. (cancer.gov)
Mesenchymal neoplasms2
- SFTs of the pleura are localized mesenchymal neoplasms composed of fibroblastlike cells believed to arise from the subpleural connective tissue. (medscape.com)
- Gastrointestinal schwannomas are rare benign neoplasms that are distinctively unique when compared to soft-tissue and central nervous system mesenchymal neoplasms. (sages.org)
Usually benign2
- A rare neoplasm, usually benign, derived from mesenchymal fibroblasts located in the submesothelial lining of the PLEURA. (bvsalud.org)
- Mixed histologies, such as angiolipomas and fibrolipomas, are often encountered and are usually benign. (medscape.com)
Rare benign1
- The prognosis for a rare benign form is usually good. (biketraffic.org)
Carcinoma2
- By definition, pseudomesotheliomatous carcinoma refers to an epithelial neoplasm that secondarily involves the pleura and encases the lung, thereby simulating the radiologic and macroscopic appearance of malignant mesothelioma. (medscape.com)
- Benign thyroid nodules were more frequent than thyroid carcinoma. (bvsalud.org)
Fibroma1
- The term fibroma is inappropriate because the neoplasm exhibits defined histologic features that differ from those of fibromas and may express malignant behavior. (medscape.com)
Asbestos4
- Whereas pleural mesothelioma is highly associated with asbestos exposure , nonmesotheliomatous cancers have generally not been proven to result from exposure to airborne asbestos. (medscape.com)
- Pleural mesotheliomas have been linked to exposure to asbestos. (enquirebio.com)
- Exposure to asbestos is the main but not the only cause of malignant pleural mesothelioma. (biketraffic.org)
- Although asbestos production has been almost completely reduced, there is still a noticeable increase in the incidence of pleural mesothelioma, which is associated with high exposure to its harmful effects in earlier years. (biketraffic.org)
Soft-tissue1
- Synovial sarcoma is a malignant soft-tissue neoplasm that most commonly affects the extremities near to, but not in continuity with, large joints. (medscape.com)
Diseases2
- Experience in the SEER registries has shown that using the Supplemental List increases casefinding for benign brain and CNS, hematopoietic neoplasms, and other reportable diseases. (cancer.gov)
- Posttransplant lymphoproliferative disorders (PTLDs) are a group of diseases that range from benign polyclonal to malignant monoclonal lymphoid proliferations. (iriakerala.org)
Fibrous1
- Solitary fibrous tumour (SFT) is an uncommon neoplasm at the orbital level that behaves in benign way in most cases [ 1 ]. (scitechnol.com)
Lymphoproliferative1
- Castleman disease otherwise known as angiofollicular or benign giant lymph node hyperplasia is an uncommon benign lymphoproliferative disorder. (iriakerala.org)
Cavity3
- The pleural space (cavity) in a healthy patient is a potential space sandwiched between the parietal and visceral pleurae. (medscape.com)
- Playing a vital role in respiration, the potential space of the pleural cavity in healthy patients conjoins the natural outward movement of the chest wall to that of the natural inward movement of the lungs via two mechanisms. (medscape.com)
- DSRCT was first described by Gerald and Rosai in 1989 as a primitive neoplasm of children and young adults that most frequently occurs in the serosa of the pelvic cavity. (medscape.com)
Thoracoscopy2
- Diagnostic thoracoscopy with histopathologic analysis of pleural biopsies served as the reference standard. (nih.gov)
- Medical thoracoscopy is well tolerated and allows direct visualization and biopsy of pleural processes under conscious sedation. (mesothelioma-line.com)
Abnormalities1
- Thirty-one consecutive patients with pleural abnormalities suspicious for MPD underwent whole-body positron emission tomography (PET)/computed tomography (CT) and thorax MR examinations. (nih.gov)
Mesothelioma5
- Mesothelioma, malignant (MESOM) [MIM:156240]: An aggressive neoplasm of the serosal lining of the chest. (enquirebio.com)
- The immunohistochemical phenotype of the spindle cells favored a spindle and epithelioid cell neoplasm, mesothelioma. (mesothelioma-line.com)
- Mesothelioma is the most common pleural cancer. (biketraffic.org)
- Pleural mesothelioma is most often diagnosed in men over 60 years of age. (biketraffic.org)
- Blood cell DNA methylation biomarkers in preclinical malignant pleural mesothelioma: The EPIC prospective cohort. (who.int)
Lymphatic1
- The normal pleural space contains approximately 10 mL of fluid, representing the balance between (1) hydrostatic and oncotic forces in the visceral and parietal pleural capillaries and (2) persistent sulcal lymphatic drainage. (medscape.com)
Cysts1
- Benign ovarian masses include functional cysts (eg, corpus luteum cysts) and neoplasms (eg, benign teratomas). (msdmanuals.com)
Spindle cells1
- Histologically IMT is considered a benign lesion consisting of myofibroblastic spindle cells with a prominent inflammatory infiltrate composed of plasma cells and lymphocytes. (eurorad.org)
Diagnostic1
- The diagnostic utility of finding eosinophils in the pleural space was assessed from its impact on prior probabilities of disease. (nih.gov)
Inflammation1
- Tietze syndrome is a benign inflammation of one or more of the costal cartilages. (wikipedia.org)
Pulmonary1
- [ 12 ] Rare cases of primary pulmonary or pleural DSRCT have subsequently been identified. (medscape.com)
Behavior1
- Clinical behavior is typically benign, although rare local recurrences occur. (cap.org)
Fluid2
- Second, a diminutive volume of pleural fluid (calculated at 0.13 mL/kg of body weight under normal situations) serves as the lubricant to facilitate the normal physiologic sliding motion of both pleural surfaces against each other during inspiration and expiration. (medscape.com)
- This concept becomes more challenging when evaluating hematolymphoid neoplasm in body fluid. (cytojournal.com)
Clinical2
- Diagnosing hematolymphoid neoplasm by evaluating fine-needle aspiration (FNA) cytology sample is controversial and requires experience and clinical skills. (cytojournal.com)
- They have a benign clinical course and a low recurrence rate after surgical excision. (medscape.com)