• Tumors of the pituitary gland are usually benign adenomas and account for 10% of all intracranial neoplasms. (ox.ac.uk)
  • Gastrointestinal stromal tumors (GISTs) account for less than 1% of GI tumors, but they are the most common mesenchymal neoplasms of the GI tract. (medscape.com)
  • Background: Perivascular epithelioid cell tumours (PEComas) are mesenchymal neoplasms with variable biological behaviour, ranging from benign to extremely aggressive diseases able to metastasize. (fortuneonline.org)
  • Although Hürthle cell carcinoma was previously considered a variant of follicular cell neoplasms, which are generally less aggressive, the 2017 World Health Organization (WHO) classification of endocrine tumors reclassified it as a distinct entity. (medscape.com)
  • Proliferating Trichilemmal Tumors (PTTs) are neoplasms derived from the outer root sheath of the hair follicle. (scitechnol.com)
  • 1] In pathology, grading is a measure of the cell appearance in tumors and other neoplasms. (netlify.app)
  • others apply also to benign neoplasms. (netlify.app)
  • The finding of pronounced nuclear pleomorphism associated with prominent myxoid matrix in an otherwise leiomyogenic tumour has not been previously reported at this site and must be distinguished from other neoplasms and non-neoplastic processes. (bmj.com)
  • These are benign neoplasms with insidious onset and low proliferation activity, and therefore are only exceptionally detected by 18F-FDG PET/CT. (viamedica.pl)
  • Pituitary adenomas (PA) are commonly occurring benign neoplasms. (cancerindex.org)
  • the induction of benign neoplasms may in some circumstances (see Section 9) contribute to the judgement that the exposure is carcinogenic. (who.int)
  • She noted that specialists should understand and consider the inter-tumour heterogeneity as an essential step to individualize therapy based on biomarkers and to identify new targets. (uroweb.org)
  • Biomarkers for identification of these histologically identical WHO II tumors do not exist. (nature.com)
  • Altered expression of the L-arginine/nitric oxide pathway in ovarian cancer: metabolic biomarkers and biological implications. (stanford.edu)
  • This method allowed for the precise quantification of targeted metabolite biomarkers using an OC blood cohort comprising control samples (n = 464), benign samples (n = 3), and OC samples (n = 13).Eleven functional modules were identified as significant differentiators (false discovery rate, FDR (stanford.edu)
  • Potential biomarkers that signal the development of the tumor would form the basis for early detection blood tests to complement imaging. (canaryfoundation.org)
  • Additional work aims to identify biomarkers that distinguish women with cancer from those with benign conditions (such as a cyst). (canaryfoundation.org)
  • Biological markers (biomarkers) allow scientists to capture what's happening within a cell or an organism at any moment. (rgcc-international.com)
  • However, these biomarkers can only be evaluated after the surgical removal of the tumor, and thus are invasive, cumbersome, and undergo prolonged processing. (scielo.br)
  • In cancer, the development of blood vessels can feed tumors and allow them to grow, and drugs that block angiogenesis are being tested as cancer treatment. (ucsfhealth.org)
  • In cancer treatment, angiogenesis inhibitors may prevent the growth of new blood vessels that tumors need to grow. (cancer101.org)
  • In this way, imaging physicians' attention to tumor blood vessels is strengthened, which is helpful to further improve the level of accurate diagnosis and treatment of breast cancer. (med-sci.cn)
  • Erosion of the tumor into blood vessels in adjacent tissues, or areas of necrosis within the tumor, can lead to hyphema or vitreous hemorrhage. (medscape.com)
  • Although mammography and ultrasonography (US) generally are important in the diagnosis of breast lesions, they have not been reliable in differentiating benign phyllodes tumors from malignant phyllodes tumors or from fibroadenomas. (medscape.com)
  • Open excisional breast biopsy for smaller lesions and incisional biopsy for large lesions are the definitive methods for diagnosing phyllodes tumors. (medscape.com)
  • Genotyping of 69 histiocytic lesions revealed that 23/48 Langerhans cell lesions were BRAF -V600E-mutant whereas all non-Langerhans cell lesions (including dendritic cell sarcoma, juvenile xanthogranuloma, Rosai-Dorfman disease, and granular cell tumor) were wild-type. (oncotarget.com)
  • The clinical manifestations of the currently recognized disease entities are highly variable and range from benign localized lesions to highly aggressive systemic diseases[ 4 ]. (oncotarget.com)
  • Permissive histologic interpretation may result in the designation of some non-neoplastic Hürthle cell lesions as malignant tumors. (medscape.com)
  • We evaluated the semiquantitative expression of ALDH1 using a score based on positive cells rate and staining density in benign lesions. (omicsonline.org)
  • Cases of endocervical adenocarcinoma (n = 90), adenocarcinoma in situ (AIS) (n = 32), benign glandular lesions (n = 36), and normal endocervical mucosa (n = 5) were selected from Stony Brook Medicine and the University of Massachusetts from 2002 to 2013. (medscape.com)
  • K17 was not detected in the epithelial cells of benign glandular lesions, but groups of cuboidal cells, residing beneath the epithelial layer of benign glands, were frequently positive for K17, especially in cases of microglandular hyperplasia. (medscape.com)
  • Background: Benign fibro-osseous lesions (BFOL) comprise a diverse group of pathologies characterized by the replacement of normal bone by fibrous tissue and a mineralized product. (bvsalud.org)
  • Tumor in these nodes portends a high risk of recurrence. (ucsfhealth.org)
  • Low AKAP12 expression in a larger cohort of patients (75) characterized tumor invasiveness, recurrence, and progression, indicating its potential as a prognostic biomarker. (nature.com)
  • As far as possible, treatment involves complete resection as the presence of remnants of intraorbital tumour tissue after the operation carries the risk of causing recurrence of the tumour and can even undergo transformation by becoming malignant [ 3 ]. (scitechnol.com)
  • Di Gioia D, Blankenburg I, Nagel D, Heinemann V, Stieber P. Tumor markers in the early detection of tumor recurrence in breast cancer patients: CA 125, CYFRA 21-1, HER2 shed antigen, LDH and CRP in combination with CEA and CA 15-3. (scielo.br)
  • Meningiomas account for approximately 13-19% of all brain tumors. (medscape.com)
  • A benign tumor made up of glandular tissue. (ucsfhealth.org)
  • Ovarian cancer is a common malignant tumor that occurs in ovarian tissue, and its incidence rate ranks third among the three major gynecological malignant tumors. (whdsbio.cn)
  • atypical squamous cells cannot exclude high grade squamous intraepithelial lesion Fibroxanthoma (M8830/0) - see also Neoplasm, connective tissue, benign. (netlify.app)
  • Fibroxanthoma - see also Neoplasm, connective tissue, benign. (netlify.app)
  • MRI has the advantages of high resolution of soft tissue, non-invasive, non-radiation and relatively objective results, which can reflect the angiogenesis in and around the tumor. (med-sci.cn)
  • Clinical applications of DSC-MRI parameters assess angiogenesis and differentiate malignant from benign soft tissue tumors in limbs[J]. Acad Radiol, 2020, 27(3): 354-360. (med-sci.cn)
  • Study of prostate tumor profiles showed that the profile (PSA+, PSMA-) expression levels decreased between normal prostate, benign prostatic tissue and primary prostate cancer. (biomedcentral.com)
  • The team is establishing a Stanford University tissue bank of matched tumor and normal breast biopsy samples, mammography, ultrasound, magnetic resonance imaging studies, and blood samples. (canaryfoundation.org)
  • During a biopsy, a small sample of tissue is taken from your lump (tumour) for analysis in a laboratory. (rgcc-international.com)
  • Analysis of tumour tissue after pituitary surgery confirmed a silent gonadotroph adenoma with low proliferation index. (viamedica.pl)
  • The ocular tissue where these tumors arise, the uvea, is a densely pigmented layer that lies for the most part between the sclera and the retina. (medscape.com)
  • A benign neoplasm cannot be distinguished from a malignant neoplasm on the basis of cytologic analysis of a fine-needle aspiration (FNA) biopsy specimen. (medscape.com)
  • Discussion Orbital SFT is a generally benign neoplasm originating from the mesenchyme, uncommon in the orbit. (scitechnol.com)
  • Solitary fibrous tumour (SFT) is an uncommon neoplasm at the orbital level that behaves in benign way in most cases [ 1 ]. (scitechnol.com)
  • The terms 'neoplasm' and 'tumour' are used interchangeably. (who.int)
  • Although the classifications according to the clinical appearances and cell appearance in cytodiagnostics give indications of the biological behavior (benign or malignant) and thus the prospect of cure, this tumor disease is unpredictable and should be treated at an early stage. (wikipedia.org)
  • Of these, three displayed particularly aggressive biological behavior, whereas there were no clinical details provided for the others. (ox.ac.uk)
  • This study was designed to test the hypothesis that genetic deletions are a marker of invasive behavior and to identify the loci most commonly involved. (ox.ac.uk)
  • In addition, allelic deletion correlates with increasingly invasive behavior (modified Hardy classification), as 73% of grade 4 tumors compared to 33% of grade 3 and 9.5% of grade 1 and 2 tumors demonstrated LOH at any locus. (ox.ac.uk)
  • Early identification of tumors with likely invasive potential by means of genetic analysis (LOH) may provide useful information on potential tumor behavior and aid tumor management in a manner that is not possible using routine histological methods. (ox.ac.uk)
  • New insights emerged last decade that enriched our knowledge regarding the biological behavior of appendiceal neuroendocrine tumors (NETs), which range from totally benign tumors less than 1cm to goblet cell carcinomas which behave similarly to colorectal adenocarcinoma. (wjgnet.com)
  • Recent advances in biological research have brought the search for markers that can help to classify, characterize or understand the behavior of groups of pathologies. (bvsalud.org)
  • The ability of a tumor to resist chemotherapy treatment following an initial response. (ucsfhealth.org)
  • Adjuvant therapy may include chemotherapy, radiation therapy, hormone therapy, targeted therapy or biological therapy. (cancer101.org)
  • Adjuvant therapies can include biological therapy, chemotherapy, hormone therapy and radiotherapy. (rgcc-international.com)
  • Radiation therapy does not appear to be beneficial and the efficacy of chemotherapy has not been demonstrated in this type of tumour. (scitechnol.com)
  • Fine-needle aspiration (FNA) for cytologic examination usually is inadequate for the diagnosis of phyllodes tumors. (medscape.com)
  • Detail information about cause, symptoms, diagnosis and treatment of Benign Prostate Hypertrophy (BPH) BPH has been explained in Ayurvedic texts long back. (hpathy.com)
  • The aim of cytoreductive surgery is to confirm the diagnosis, define the extent of disease, and resect all visible tumor. (medscape.com)
  • Although cancer antigen 125 (CA125) is widely used in the clinical diagnosis of ovarian cancer detection, studies have shown that HE4 is superior to CA125 in the early diagnosis of ovarian cancer, especially for patients with benign ovarian cancer, HE4 is currently ovarian cancer The most sensitive tumor marker for diagnosis. (whdsbio.cn)
  • Immunohistochemical evidence for leiomyogenic markers coupled with the low mitotic rate, the lack of an infiltrating growth pattern, and the indolent clinical course led to the diagnosis of atypical leiomyoma with prominent myxoid change. (bmj.com)
  • The patient was referred to neurosurgery after confirming the diagnosis and because of intracranial invasion of the tumour. (scitechnol.com)
  • Unlike the invasive carcinomas, borderline ovarian tumors are characterized by cytoplasmic and nuclear atypia, (element of differential diagnosis with benign tumors), absence of stromal invasion, (element of differential diagnosis with malignant tumors), unusual degree of proliferation of the epithelial cells with cellular stratification including remarkable architectural atypia and the formation of papillary protuberances. (intechopen.com)
  • Consensus regarding the diagnosis, prognosis and treatment of canine and feline mammary tumors-2019. (scielo.br)
  • Diagnosis of malignant pleural effusion with combinations of multiple tumor markers: A comparison study of five machine learning models. (cdc.gov)
  • Its metastatic potential depends on the phenotype of the tumor cells, and it frequently disseminates before diagnosis. (medscape.com)
  • Benign microscopic breast changes known as atypical hyperplasia may increase a woman's risk of developing breast cancer. (ucsfhealth.org)
  • The World Health Organization (WHO) histologically classifies tumors into three grades: benign (I), atypical (II) and anaplastic (III) 2 . (nature.com)
  • Although most meningiomas are benign, 15-35% represents atypical or anaplastic forms 3 . (nature.com)
  • Skin nonmelanocytic tumor - Atypical fibroxanthoma (AFX), Rare, low grade, malignant cutaneous tumor of uncertain differentiation, first described in the 1960s by EB Helwig Atypical fibroxanthoma (AFX) is a dermal spindle-cell tumour that typically occurs on the head and neck of sun damaged older people. (netlify.app)
  • 2016-11-01 Atypical fibroxanthoma (AFX) is a dermal spindle-cell tumour that typically occurs on the head and neck of sun damaged older people. (netlify.app)
  • Morfological Codes ICD 3 Atypical proliferative papillary serous tumor (C56.9). (netlify.app)
  • 8463/1, Serous surface papillary tumor of Atypical fibroxanthoma. (netlify.app)
  • [ 5 ] The 2022 WHO classification of endocrine tumors has replaced the term Hürthle cell carcinoma with oncocytic carcinoma. (medscape.com)
  • The value of adjacent vessel sign in malignant breast tumors[J]. Diagn Interv Radiol, 2022, 28(5): 463-469. (med-sci.cn)
  • The extent of surgery in nonfunctioning pancreatic neuroendocrine tumors (NF-PNETs) has not well established, partly owing to the dilemma of precise prediction of lymph node metastasis (LNM) preoperatively. (springeropen.com)
  • Ovarian cancer is the most common cause of cancer death from gynecologic tumors in the United States. (medscape.com)
  • Some biological therapies stimulate or suppress the immune system to help the body fight cancer, infection, and other diseases. (cancer101.org)
  • Other biological therapies attack specific cancer cells, which may help keep them from growing or kill them. (cancer101.org)
  • Biomarker testing or tumor profiling reads the instruction manual of cancer cells to identify the mistakes, or genomic mutations that may cause your cancer to grow. (cancer101.org)
  • A bone scan may be used to diagnose bone tumors or cancer that has spread to the bone. (cancer101.org)
  • Some areas of active research include defining "molecular signatures" of disease, developing paradigms to image multiple markers of disease simultaneously, developing methods to image intracellular disease markers in breast cancer, and developing molecular imaging technologies that allow for intraoperative assessment of disease progression. (case.edu)
  • Human epididymis protein 4 (HE4) is a tumor cell surface antigen in female ovarian cancer. (whdsbio.cn)
  • Recent research demonstrates that tumors originate from the Cancer S tem Cells (CSCs) or Tumor Initiated Cells (TIC) [ 1 ], which are called breast cancer stem cells in breast cancer. (omicsonline.org)
  • A Gleason 6 Tumor: Is It Cancer, and Should It Be Treated? (ascopost.com)
  • A new controversial question has arisen in prostate cancer: Is a tumor with a Gleason 6 score a potential killer, or should it be left alone? (ascopost.com)
  • Is a Gleason 6 Tumor Cancer? (ascopost.com)
  • Likewise, cancer pathologies (both benign and malignant) will be investigated. (unige.it)
  • The tumour-like growth should be considered a type of skin cancer but it may behave in a benign fashion. (netlify.app)
  • The present study was undertaken to relate the co-expression of prostate-associated antigens, PSMA and PSA, with the degree of vascularization in normal and pathologic (hyperplasia and cancer) prostate tissues to elucidate their possible role in tumor progression. (biomedcentral.com)
  • We are testing several imaging alternatives, including a new PET imaging agent, enhanced ultrasound using targeted microbubbles, and photoacoustic imaging , for their ability to identify breast cancer early and to better distinguish cancer and benign conditions. (canaryfoundation.org)
  • Biological therapies use living organisms, or laboratory-produced synthetic versions, to treat cancer. (rgcc-international.com)
  • Biological therapies include immunotherapy, which stimulates the body's immune system to act against cancer cells within the body. (rgcc-international.com)
  • Other forms of biological therapy can include treatments to slow the growth and progress of tumours or introducing antibodies which can disrupt cancer cell activity. (rgcc-international.com)
  • This provides information on the sensitivity or resistance of the patient's tumour cells to certain cancer drugs and shows options for targeted therapy or an alternative treatment method with organic substances. (rgcc-international.com)
  • While some techniques only perform the task of cell nuclei segmentation and quantification, techniques that are capable of further detecting and classifying abnormal tumors (cell nuclei) that cause various types of cancer have also been proposed. (hindawi.com)
  • Shao Y, Sun X, He Y, Liu C, Liu H. Elevated levels of serum tumor markers CEA and CA15-3 are prognostic parameters for different molecular subtypes of breast cancer. (scielo.br)
  • Associations of a Breast Cancer Polygenic Risk Score With Tumor Characteristics and Survival. (cancercentrum.se)
  • Since 2016, when the updated fourth edition of World Health Organization (WHO) classification of tumors of the central nervous system was published, it has been emphasized to classify ependymomas by anatomic site and molecular signatures associated genetic alterations so that classification of the disease reflects its underlying biology. (bvsalud.org)
  • Also called molecular marker and signature molecule. (cancer101.org)
  • Molecular imaging, defined as the in vivo characterization of biological processes at the cellular and molecular level, is an attempt to image the molecular make-up of the macrofeatures currently visualized using "classical" diagnostic imaging techniques. (case.edu)
  • Specifically we are interested in designing novel imaging tools to image individual and multiple molecular markers of disease. (case.edu)
  • The understanding of cellular and molecular processes involved in tumour development and especially in tumour progression and metastasis in general, but also in each tumour and tumour subtype will increase the therapeutic options. (uroweb.org)
  • Several university hospitals established interdisciplinary molecular tumour boards, which is one of the steps in this direction," she said. (uroweb.org)
  • Two tumors can look alike under the microscope and have the same Gleason score, but they can have a different molecular profile and demonstrate different clinical behaviors. (ascopost.com)
  • Scholarly interests include investigation of molecular markers of human disease that provide diagnostic function, serve as targets for possible therapeutic manipulation, or provide insight into mechanisms of human disease. (stanford.edu)
  • conducted a comprehensive algorithm to identify MF based on clinical, histopathological, immunopathological, and molecular biological features. (iranjd.ir)
  • These markers, mainly signatures or combination of markers, can be defined in primary tumors to predict the risk of metastasis based on the individual biological background," said Prof. Dr. Kerstin Junker of the Clinic of Urology and Pediatric Urology at Saarland University Homburg/Saar (DE). (uroweb.org)
  • Overall, only about 33% of Hürthle cell tumors demonstrate signs of that invasive growth that indicates malignancy and the possibility of metastasis. (medscape.com)
  • The study was carried out in 6 normal, 44 benign prostatic hyperplastic and 39 cancerous human prostates. (biomedcentral.com)
  • A benign tumour is a medical term for a non-cancerous tumour. (rgcc-international.com)
  • RCC are subdivided into histologically defined subtypes, and the most common subtypes are clear cell RCC (70-75%), papillary RCC (10-15%), chromophobe RCC (5%) and the benign oncocytomas. (uroweb.org)
  • it is, however, not as great as with papillary tumors. (medscape.com)
  • PURPOSE: Resection beyond the contrast-enhanced zone contributed to reduce tumor burden and prolong survival in glioblastomas. (bvsalud.org)
  • AFX usually has a benign clinical course and complete tumor resection is generally curative. (netlify.app)
  • It is diagnosed using immunohistochemical technique and the treatment of choice is surgical resection of the tumour in order to prevent recurrences. (scitechnol.com)
  • Usually, local resection of the tumour is sufficient. (scitechnol.com)
  • However, in some situations, infiltration of the tumour requires more extensive resection of adjacent tissues. (scitechnol.com)
  • Primary Cutaneous Neuroendocrine Tumors Ceruminous gland tumors are discussed in Tumors of the Ear Canal. (merckvetmanual.com)
  • reticulum cell sarcomas, cutaneous nodular amyloidosis) are relatively common cutaneous tumors. (merckvetmanual.com)
  • Cutaneous tumors derived from the outer root sheath of hair follicles, which show trichilemmal keratinization, are trichilemmal, proliferating trichilemmal, and malignant proliferating trichilemmal cysts. (scitechnol.com)
  • Low expression of oncogene-induced senescence markers did not support senescence as the explanation for the tumour's low proliferative activity although it was in consonance with the hormonal activity. (viamedica.pl)
  • CONCLUSIONS: Applying en-bloc technique and achieving SMR, which could reduce tumor burden and did not increase additional complications, both had remarkedly positive effects on clinical outcomes in patients with primary supratentorial lobar glioblastomas. (bvsalud.org)
  • But we have to validate these highly potential markers in clinical trials as we are doing it for new therapeutics. (uroweb.org)
  • We present two clinical cases of patients aged 36 and 74 with an orbital solitary fibrous tumour (SFT). (scitechnol.com)
  • In the patch and plaque stages, it can mimic the clinical features of benign dermatoses. (iranjd.ir)
  • The treatment for renal parenchymal tumors has changed over time, and this trend continues today as a result of technological progress made with clinical research and improved diagnostic and therapeutic tools. (biomedcentral.com)
  • Allelic deletion in pituitary adenomas reflects aggressive biological activity and has potential value as a prognostic marker. (ox.ac.uk)
  • Thus, to improve overall survival, new diagnostic and prognostic markers are urgently needed. (univie.ac.at)
  • Besides blood cell gene expressions, tumor proliferation markers and tumor infiltrating leukocytes are promising prognostic biological markers in EOC patients. (univie.ac.at)
  • K17 is highly expressed in most cases of both invasive adenocarcinoma and in AIS and is a powerful, negative prognostic marker for patient survival. (medscape.com)
  • Stromal tumors of the ovary include germ-cell tumors, sex-cord stromal tumors, and other more rare types. (medscape.com)
  • Dichloromethane (DCM) is possibly carcinogenic to human s (Group 2B) based on sufficient evidence in experimental animals [lung and liver tumors in mice exposed by inhalation, and mammary tumors in rats (both sexes) exposed by inhalation]. (who.int)
  • Of the 11 loci investigated, 75% of the allelic deletions identified in invasive tumors were found at 4 loci: 11q13, 13q12-14, 10q, and 1p. (ox.ac.uk)
  • Twenty of 47 invasive tumors had evidence of at least 1 allelic deletion, whereas 14 of 20 had more than 1. (ox.ac.uk)
  • 0.05) in invasive tumors. (ox.ac.uk)
  • For recurrent, invasive tumors, more aggressive attempts at excision or electroporation may be required. (merckvetmanual.com)
  • It is a slowly growing tumor, usually benign, but displays a marked propensity for invasive growth. (curehunter.com)
  • 23 patients including EOC patients, patients with other malignancies and controls with benign gynecological diseases were compared. (univie.ac.at)
  • In hematological malignancies, tumor-derived EVs might reprogram the bone marrow environment, suppress antileukemic immunity, mediate drug resistance and interfere with immunotherapies. (nature.com)
  • We investigate and discuss tumour biology in light of increased 18F-FDG avidity in a symptom-free, 70-year-old male patient, previously treated for two different malignancies (lung and rectal). (viamedica.pl)
  • Special attention should be paid to evaluation of 18F-FDG avid pituitary adenomas in patients with multiple malignancies, bearing in mind that avidity does not always mirror its biological behaviour. (viamedica.pl)
  • Tumour development, histology and grade of breast cancers: prognosis and progression. (who.int)
  • The link between chronic inflammation and tumor progression/promotion. (unige.it)
  • therefore, definitive differentiation of Hürthle cell carcinoma from Hürthle-cell adenoma is based on vascular invasion and/or capsular invasion, as well as on permanent histologic sections or extrathyroidal tumor spread and lymph node and systemic metastases. (medscape.com)
  • The novel MRI-based model considering regular shape of primary tumor and short axis of largest lymph node in the regional area can accurately predict lymph node metastases preoperatively in NF-PNETs patients, which might facilitate the surgeons' decision on risk stratification. (springeropen.com)
  • 2 cm or those with positive lymph nodes, while for tumors of 1-2 cm, lymphadenectomy should be considered [ 9 ]. (springeropen.com)
  • 1 A recent literature review found only 22 cases of benign leiomyogenic tumours arising in the nose and paranasal sinuses. (bmj.com)
  • Benign tumours can cause medical problems if left untreated. (rgcc-international.com)
  • Differentiation of malignant from benign pleural effusions based on artificial intelligence. (cdc.gov)
  • The granules are stored histamine, heparin as well as cytokines such as tumor necrosis factor-α. (wikipedia.org)
  • This strategy was used to better understand the underlying mechanisms of meningioma malignancy, aid in the development of novel therapies and markers of poor prognosis. (nature.com)
  • Borderline ovarian tumors represent 10-20% of epithelial ovarian neoplasm's [ 5 ] with an incidence of 1.8-4.8 out of 100.000 women per year [ 6 ] and typically have an excellent prognosis. (intechopen.com)
  • Unfortunately, for men between the age of 40 and 59, nearly 60% can be shown to already be suffering from benign prostatic hyperplasia ( Homeopathy Treatment for Benign Prostate Hypertrophy ) or prostate enlargement. (hpathy.com)
  • Benign prostatic hyperplasia (formerly called hypertrophy) in some ways is the male equivalent of menopause. (hpathy.com)
  • We measured erbB mRNA in thyroid tissues of benign and malignant thyroid tumors or Graves' disease using Genescan. (fujita-hu.ac.jp)
  • A biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. (cancer101.org)
  • In the other hand, the profile (PSA-, PSMA+) expression levels increased from normal to prostate tumor tissues. (biomedcentral.com)
  • AKAP12 knockdown in benign meningioma cells SF4433 increases proliferation, cell cycle, migration, invasion, and confers an anaplastic profile. (nature.com)
  • B) At histological examination, the tumour consisted of a proliferation of spindle shaped, pleomorphic cells with eosinophilic cytoplasm in a prominent myxoid background. (bmj.com)
  • Five pituitary tumors have previously been reported to harbor multiple allelic deletions. (ox.ac.uk)
  • Accordingly, we studied two cohorts of pituitary tumors, classified radiologically as invasive or noninvasive, for loss of heterozygosity (LOH). (ox.ac.uk)
  • Furthermore, in some tumors we identified a breakpoint between markers intragenic and extragenic to the retinoblastoma gene (Rb1) on chromosome 13q, suggesting that tumor suppressor genes other than or in addition to Rb1 may be involved in pituitary tumorigenesis. (ox.ac.uk)
  • However, the continuous knowledge which was added by studying these tumors for nearly a century strengthen the notion that the above term was inaccurate or inadequate to describe several parameters of this heterogeneous group of gastrointestinal tumors (including the appendiceal one). (wjgnet.com)
  • NF‑PNETs are associated with heterogeneous biological behaviors ranging from indolent to highly aggressive [ 6 ]. (springeropen.com)
  • Of the 6 tumors with only 1 deletion, 5 involved the 11q13 locus, suggesting that this is an early change in the transition from noninvasive to invasive adenoma. (ox.ac.uk)
  • The average survival time for malignant tumors is only four months, whereas for benign tumors it is over two years. (wikipedia.org)
  • For tumors resistant to radiation and for those animals unable to receive radiation therapy, systemic treatment with administration of chemotherapeutic agents, including melphalan, chlorambucil, cyclophosphamide, and glucocorticoids, have been recommended and have yielded long-term survival. (merckvetmanual.com)
  • Such meetings are beneficial because they present an interdisciplinary view on specific urological tumour diseases including not only standard therapy recommendations but also modern knowledge about future directions," Junker said. (uroweb.org)
  • A retrospective study by Kawashima et al suggested that intravoxel incoherent motion (IVIM) MRI could differentiate phyllodes tumors from fibroadenomas by comparing the apparent diffusion coefficient (ADC) values. (medscape.com)
  • This study demonstrated a way to differentiate MF from other benign dermatoses in the early stages by measuring the CD7 marker. (iranjd.ir)
  • In addition, mast cells may contribute to the development and growth of other skin tumors due to their large repertoire of biologically active substances. (wikipedia.org)
  • In addition, we learned that not only tumour cells but also the tumour microenvironment (or tumour stroma) including fibroblasts, endothelial cells and immune cells are important players in tumorigenesis and should be used for biomarker discovery and therapy targets," said Junker. (uroweb.org)
  • Furthermore, other cells at the interface of the innate and the adaptive immune system (e.g cytokine-induced killer cells (CIK) or invariant natural killer T-cells (iNKT)) are important mediators in antitumor-, autoimmune-, and antimicrobial responses and tumor surveillance. (nature.com)
  • No, due to the blood-brain barrier, tumour cells cannot enter the bloodstream. (rgcc-international.com)
  • This means that we cannot obtain and isolate any tumour cells from the blood sample. (rgcc-international.com)
  • Is it possible to measure circulating tumour cells (CTC) in patients with lymphoma or leukaemia? (rgcc-international.com)
  • Yes, patients with lymphoma or leukaemia can use an RGCC test to measure the number of circulating tumour cells (CTC) they have. (rgcc-international.com)
  • Soluble mesothelin-related proteins released into the serum by mesothelial cells are being studied as possible tumor markers for disease detection and monitoring, but the false-positive rate may limit their effectiveness. (msdmanuals.com)
  • The human renal cell carcinoma cell line A498 under hypoxia/normoxia was used as an experimental model in vitro and the biological characteristics and mitochondrial function of the cells were assessed. (biomedcentral.com)
  • Tumor-induced glaucoma may be produced by obstruction of outflow pathways by pigment cells (pigment dispersion syndrome), melanin-laden macrophages (melanomalytic glaucoma), or tumor cells. (medscape.com)
  • [ 18 ] Further exploration of the biology of phyllodes tumor may lead to the development of targeted treatments. (medscape.com)
  • Junker said genetic analyses have confirmed that these subtypes are characterized by different chromosomal alterations which suggest that each subtype represents a distinct tumour entity with different tumour biology. (uroweb.org)
  • Thus, this course focuses on the biology of benign and malignant neoplasias. (unige.it)
  • A type of radiation therapy in which radioactive material sealed in needles, seeds, wires, or catheters is placed directly into or near a tumor. (cancer101.org)
  • When tumors are multiple or when surgical excision is not feasible, radiation therapy appears to be the best secondary treatment. (merckvetmanual.com)
  • Radiation is used as adjuvant to treat progressive tumors since there are no efficient chemotherapies for the management of high-grade tumors that fail treatments. (nature.com)
  • Intervention such as radiation treatment or surgery is offered if evidence of a more aggressive or growing tumor develops. (canaryfoundation.org)
  • related chemical compounds, physical agents (such as radiation) and biological factors (such as viruses). (who.int)
  • A small (N = 12) single-institution retrospective study by Johnson et al reported disproportionate rates of aggressive histopathologic features among Black women with phyllodes tumor as compared with non-Black women. (medscape.com)
  • All phyllodes tumors contain a stromal component that can vary significantly in histologic appearance from one lesion to another. (medscape.com)
  • ii) the characteristics of the immune system in elderly subjects usually characterized by both a de-regulation of inflammatory processes and by a reduced capability to react against pathogens and tumor. (unige.it)
  • Chemical analogues and compounds with biological or physical characteristics similar to those of suspected carcinogens may also be considered, even in the absence of data on a possible carcinogenic effect in humans or experimental animals. (who.int)
  • The current method of diagnosing canine osteosarcoma is done with a CT scan, followed by a biopsy to determine if the tumor is benign or malignant, a procedure that is invasive and costly. (oregonstate.edu)
  • Homeopathy for Prostate Enlargement (BENIGN HYPERTROPHY OF PROSTATE GLAND) with indications of commonly used homeopathy medicines. (hpathy.com)
  • This gland when affected by vitiated vata causes a disease called "vataashteela" (or benign prostate hypertrophy). (hpathy.com)
  • This deregulation may result in production of prostate specific markers such as the secreted protease prostate-specific antigen (PSA) and the cell surface prostate-specific membrane antigen (PSMA) [ 4 ]. (biomedcentral.com)
  • subsequently, this group of tumors of the ovary were classified in 1973 by the World Health Organization as "low malignant potential ovarian tumor" [ 2 ] and, finally, in 2003 WHO separates them from carcinomas and call them borderline tumors. (intechopen.com)
  • Proliferating Trichilemmal Tumor (PTT) is an uncommon append age al skin tumor that affects mainly elderly women. (scitechnol.com)
  • [ 16 ] In general, benign phyllodes tumors demonstrate a markedly increased number of regular fusiform fibroblasts in the stroma. (medscape.com)
  • a classification based on pathological and histological data has been proposed to predict the biological behaviour of the PEComas, but not yet validated [2]. (fortuneonline.org)
  • Histiocytic tumors are derived from the mononuclear-phagocytic and histiocyte system[ 1 - 3 ]. (oncotarget.com)
  • Tumors for which surgical removal is not possible or only incompletely possible can also be treated with tyrosine kinase inhibitors. (wikipedia.org)
  • [ 29 ] Adam et al concluded that the surgical margin should be at least 5 mm regardless of tumor grade. (medscape.com)
  • Most of these tumors are locally confined, and complete but conservative surgical excision is the treatment of choice. (merckvetmanual.com)
  • A literature survey confirmed that such a tumour is extremely rare at this site, but the biological behaviour seems to be similar to its uterine counterpart. (bmj.com)
  • Any of various biological or biochemical indicators that serve to detect exposures to carcinogenic processes or to predict carcinogenic disposition. (ucsfhealth.org)
  • Finally, the role of inflammation in biological aging processes will be assessed. (unige.it)
  • To know how the response affects both the biological and the pathological processes in the elderly subjects. (unige.it)
  • Role of Inflammation in Biological Aging Processes. (unige.it)
  • Androgens are the main physiologic anabolic steroid hormones and normal testosterone levels are necessary for a range of developmental and biological processes, including maintenance of muscle mass. (frontiersin.org)
  • Types of biological therapy include immunotherapy (such as vaccines, cytokines, and some antibodies), gene therapy, and some targeted therapies. (cancer101.org)
  • The chronic inflammatory process is one of the factors involved in many pathologies involving older people (such as ATS, AD, tumors, and type 2 diabetes). (unige.it)
  • Renal function indexes, serum inflammatory factors, and tumor markers were evaluated. (biomedcentral.com)
  • Nursing based on oxygen administration decreased the value of renal function indexes, serum inflammatory factors, and tumor markers in renal cell carcinoma patients. (biomedcentral.com)
  • In 1907, Oberndorfer[ 1 ] first introduced the term "carcinoid" to describe "little carcinomas" of the small intestine which were thought (by him at that time) to be probably benign. (wjgnet.com)
  • A study investigating a malignant phyllodes tumor with whole genomic and proteomic analysis revealed chromosome mutations, amplifications, and deletions. (medscape.com)