• Porphyromonas gingivalis Fusobacterium nucleatum is found between the early and late colonisers, linking them together. (wikipedia.org)
  • Furthermore, the antimicrobial abilities evaluated in vitro with Streptococcus mutans ( S. mutans ), Fusobacterium nucleatum ( F. nucleatum ) and Candida albicans ( C. albicans ) using the live/dead, MTT and colony-forming units (CFUs) assay. (peerj.com)
  • This study investigated the correlation between Tannerella forsythia, Porphyromonas gingivalis, Fusobacterium nucleatum and Aggregatibacter actinomycetemcomitans at dual sites in concurrent endodontic-periodontal diseases. (hoajonline.com)
  • Species including Filifactor alocis and Fusobacterium nucleatum were central to this network, which supports their role in the coaggregation of periodontal biofilms during disease progression. (ox.ac.uk)
  • 2) Methods: We tested the effect of matrix-bound zol on the growth and attachment of Porphyromonas gingivalis (Pg), Fusobacterium nucleatum (Fn) and Actinomyces israelii (Ai), and whether the nitrogen-containing component of zol contributed to such effect. (elsevierpure.com)
  • Fusobacterium nucleatum and Treponema denticola were found in nasopharyngeal aspirates during AOM episodes (2). (idcmjournal.org)
  • Fusobacterium nucleatum is one bacteria species found commonly in the mouth, which is a key member of colorectal cancer-associated bacteria. (lumoral.com)
  • A. oris induces the coaggregation of the early colonizers Streptococcus gordonii and Streptococcus sanguinis with the intermediate colonizer Fusobacterium nucleatum in oral biofilms [ 1 ]. (biomedcentral.com)
  • A model multi-species sub-gingival community containing Fusobacterium nucleatum, Streptococcus constellatus , Parvimonas micra with wild type or isogenic mutants of P. gingivalis was then created and growth and proteolytic activity in serum assessed as above. (biomedcentral.com)
  • Some bacteria can contribute to carcinogenesis by producing toxins (such as Helicobacter pylori cytotoxin), inducing chronic inflammation (such as Fusobacterium nucleatum in colorectal cancer) or altering DNA methylation (such as Streptococcus gallolyticus in colon cancer). (stemcelldaily.com)
  • Understanding these oral floras can help in assessing various dental diseases like gingivitis and periodontitis which account for the most frequent bacterial infections in the human body. (news-medical.net)
  • Biofilms present in the oral cavity are essential for the sustenance of good oral health but an increase in the volume and complexities of these biofilms can result in diseases like gingivitis and Periodontitis. (news-medical.net)
  • Tannerella forsythia is an anaerobic, fusiform Gram-negative oral pathogen strongly associated with periodontitis, a multibacterial inflammatory disease that leads to the destruction of the teeth-supporting tissue, ultimately causing tooth loss. (karger.com)
  • Bacteriologically dental caries and periodontitis differ. (drtbalu.co)
  • In this article, he cites studies that explain the various antibiotics prescribed for periodontitis, and the effects they have on biofilms and clinical treatment modalities. (dentistryiq.com)
  • Chronic periodontitis is an interaction between a plaque biofilm and the body's immune response. (dentistryiq.com)
  • 3 The purpose of this article is to better understand the antibiotics that are prescribed for periodontitis, and what effects they have on biofilms and clinical treatment modalities. (dentistryiq.com)
  • Oral dysbiosis, which potentially causes periodontitis to subsequently promote systemic inflammation and local vascular inflammation, increases the risks of cardiovascular diseases (CVDs). (degruyter.com)
  • During oral dysbiosis and periodontitis, local inflammation in periodontal tissue and permeability of local capillaries are enhanced, therefore bacteria from oral microbiome and bacteria-released toxins can enter the systemic circulation. (degruyter.com)
  • Oral dysbiosis promotes periodontitis pathogenesis, enhancing chronic local inflammation in periodontal tissue, local production of pro-inflammatory cytokines and permeability of surrounding capillaries. (degruyter.com)
  • The inhibition of quorum sensing, called quorum quenching, may disrupt oral biofilm formation, which is the main etiological factor of oral diseases, including periodontitis. (mdpi.com)
  • Periodontitis is a chronic inflammatory disorder of infectious etiology involving the hard and soft periodontal tissues and which is related to various systemic disorders, including cardiovascular diseases, diabetes and obesity. (mdpi.com)
  • UNLABELLED: Periodontal disease ranges from gingival inflammation (gingivitis) to the inflammation and loss of tooth-supporting tissues (periodontitis). (ox.ac.uk)
  • Associations between bacterial relative abundances and gingivitis/periodontitis were investigated by using negative binomial models, adjusting for epidemiological factors. (ox.ac.uk)
  • The main differences in supragingival plaque compositions were associated more with gingivitis than periodontitis, including higher bacterial diversity and a greater abundance of particular species. (ox.ac.uk)
  • A small number of species were associated with periodontitis but not gingivitis, including members of Prevotella, Treponema, and Selenomonas, supporting a more complex disease model than a linear progression following gingivitis. (ox.ac.uk)
  • Our study includes a large number of low-income participants with poor oral hygiene and a wide range of severities, and we were therefore able to quantitatively model bacterial abundances as functions of both gingivitis and periodontitis. (ox.ac.uk)
  • This suggests the future possibility of diagnosing periodontitis based on bacterial occurrences in supragingival plaque. (ox.ac.uk)
  • This enzyme is called T reponema denticola chymotrypsin-like proteinase - or dentilisin - and it is usually found in the mouth, where it is known to contribute to severe gum disease (periodontitis). (lumoral.com)
  • Periodontitis is a highly prevalent, chronic multifactorial infectious disease, induced by the dysbiotic biofilm that triggers a persistent systemic inflammation and recurrent bacteremia. (intechopen.com)
  • There is a growing body of scientific evidence that suggests the potential implication of periodontitis in the causation and progression of various systemic disease and conditions, such as diabetes, cardiovascular disease, pulmonary disease, adverse pregnancy outcomes and cancer. (intechopen.com)
  • This chapter emphasis the relationship between periodontitis and adverse pregnancy outcomes and the underlying mechanisms that link peridontitis to oral carcinogenesis. (intechopen.com)
  • The pathogenic bacterial complex can lead to dental caries, periodontitis and gingivitis. (encyclopedia.pub)
  • In addition, dental biofilm, especially subgingival plaque in patients with periodontitis, has been associated with cardiovascular and respiratory disease and diabetes mellitus, and recently constituting a high risk for developing severe illness due to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection [ 2 ] . (encyclopedia.pub)
  • Periodontal diseases include two main conditions: gingivitis and periodontitis. (encyclopedia.pub)
  • Periodontitis is a complex, chronic inflammatory disease caused by an abnormal host response to bacteria from dental plaque. (encyclopedia.pub)
  • In periodontitis, however, the development of periodontal pockets as a result of breakdown of the bone and soft-tissues supporting the teeth, creates a new subgingival niche that promotes growth of bacterial species suited to the environment. (biomedcentral.com)
  • reduce inflammation and consequential bone loss by modulating host bacterial pathogenicity in a mouse ligature-induced periodontitis model. (metabiom.org)
  • The abundance of #Porphyromonadaceae and #Fusobacterium , which are co-pathogens in periodontitis and intestinal inflammation was significantly enriched in the gut of the C-SP group. (metabiom.org)
  • The bulk of the microorganisms that form the biofilm are Streptococcus mutans and other anaerobes, though the precise composition varies by location in the mouth. (wikipedia.org)
  • Microscopic evaluation of these biofilms indicated that streptococcus accounts for approximately 80 percent of this colonization. (news-medical.net)
  • Streptococcus mutans was previously considered a primary cause, but recent research promotes the ecologic hypothesis, in which a dysbiosis in the oral microbial community leads to caries. (researchsquare.com)
  • Streptococcus mutans has been clearly implicated in dental caries. (drtbalu.co)
  • The most common causative bacterial pathogens are Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis . (idcmjournal.org)
  • #Streptococcus salivarius K12 and M18 prevented immune activation induced by periodontal disease pathogens. (metabiom.org)
  • Dental plaque is a biofilm of microorganisms (mostly bacteria, but also fungi) that grows on surfaces within the mouth. (wikipedia.org)
  • Bacteria then attach to the pellicle layer, form micro-colonies, and mature on the tooth, which can result in oral diseases. (wikipedia.org)
  • The following table provides a more detailed (six-step) explanation of biofilm formation: Different types of bacteria are normally present in the mouth. (wikipedia.org)
  • These bacteria, as well as leukocytes, neutrophils, macrophages, and lymphocytes, are part of the normal oral cavity and contribute to the individual's health. (wikipedia.org)
  • Below is a summary of the bacteria that may be present during the phases of plaque maturation: Early biofilm: primarily Gram-positive cocci Older biofilm (3-4 days): increased numbers of filaments and fusiforms 4-9 days undisturbed: more complex flora with rods, filamentous forms 7-14 days: Vibrio species, spirochetes, more Gram-negative organisms Dental plaque is considered a biofilm adhered to the tooth surface. (wikipedia.org)
  • After some growth of early colonisers, the biofilm becomes more compliant to other species of bacteria, known as late colonisers. (wikipedia.org)
  • Studies have highlighted that if dental hygiene is not maintained these Gram-negative bacteria can infect other organs. (news-medical.net)
  • Though not always but complex dental treatments can even transport these bacteria to the bloodstream, vital organs like lungs, kidneys, and brain. (news-medical.net)
  • Regular swishing with oral disinfectants like chlorhexidine and antiseptic solutions can ward off these bacteria. (news-medical.net)
  • The human mouth serves as the best habitat for numerous bacterial species due to its alkaline condition, favourable to most bacteria and fungi. (scielo.br)
  • To survive in the oral habitat, T. forsythia depends on cohabiting bacteria for the provision of nutrients. (karger.com)
  • This report summarizes T. forsythia 's strategies to survive in the oral habitat by means of PGN salvage pathways, including recovery of exogenous MurNAc and PGN-derived fragments but also polymeric PGN, which are all derived from cohabiting bacteria either via cell wall turnover or decay of cells. (karger.com)
  • The type of bacteria found in odontogenic infections are normal commensals of the oral cavity. (drtbalu.co)
  • In addition to the above mentioned organism there are certain specific bacteria colonizing specific areas of the oral cavity. (drtbalu.co)
  • Our oral cavity houses various types of microbes including bacteria, protozoa, fungi and viruses, harboring over 700 bacterial species. (degruyter.com)
  • Although overgrowth of certain pathogenic bacteria have been indicated in some cardiometabolic diseases, it is still premature to consider oral microbiome as a suitable predictor for non-invasive diagnostic purpose. (degruyter.com)
  • Translocation of bacteria from oral cavity to intestine might exacerbate gut dysbiosis. (degruyter.com)
  • Bacteria have always been associated with disease and have caused the human race much grief. (bvsalud.org)
  • Bacteria an d bacterial products cause inflamm ation of soft tissue. (researchgate.net)
  • Oral malodor from the overgrowth of proteolytic, anaerobic gram-negative bacteria on the crevices of the tongue dorsum can be successfully diagnosed and treated. (medscape.com)
  • Oral cavity contains millions of anaerobic bacteria like fusobacterium and actinomyces which acts on the protein of food materials and putrifies them. (likehealthylife.com)
  • If oral hygiene is not maintained properly the mouth becomes the seat for millions of bacteria which produce offenssive gases by degrading the food debris. (likehealthylife.com)
  • IMPORTANCE: Periodontal disease is a major public health problem associated with oral bacteria. (ox.ac.uk)
  • The role of oral bacteria in the induction of osteonecrosis was then tested using an extra-oral bone defect model. (elsevierpure.com)
  • Does oral bacteria play a role in SARS-CoV-2 severity? (westhoustonperiodontics.com)
  • Clinicians should encourage patients with SARS-CoV-2 infection to maintain, if not improve, their oral hygiene to reduce the amount of bacteria in the mouth and lower their potential risk of getting bacterial superinfections, the authors wrote. (westhoustonperiodontics.com)
  • Bacteria present in patients with severe COVID-19 are associated with the oral cavity and improved oral hygiene may play a part in reducing the risk of complications," wrote the group, led by Victoria Sampson, BDS, of the 38 Devonshire Street practice in London. (westhoustonperiodontics.com)
  • This connection is centered around so-called oral dysbiosis, a condition where imbalanced oral bacteria can lead to a range of health issues. (lumoral.com)
  • The oral cavity houses more than 700 types of bacteria. (lumoral.com)
  • The BJC study from 2017 was the first to show that virulence factors from gum disease bacteria could spread from the mouth to other parts of the body and take part in central mechanisms of cancer-related tissue destruction. (lumoral.com)
  • The links revealed so far between oral bacteria and cancer developments have inspired Prof. Sorsa's team to search ways to help prevent cancerous developments. (lumoral.com)
  • Organic Component Organic constituents : polysaccharides, proteins, glycoproteins, and lipid material Polysaccharides produced by bacteria-Dextran: predominant form Albumin: originating from crevicular fluid Lipid material: debris from the membranes of disrupted bacterial and host cells and possibly food debris. (medicpresents.com)
  • Formation of dental Pellicle Acquired enamel pellicle forms rapidly - Early pellicle Characterized by an absence of bacteria and their products. (medicpresents.com)
  • 31 Dental personnel and patients are exposed to tens of thousands of bacteria per cubic meter, and the potential to breathe infective material that is aerosolized during routine procedures is high. (aeroshieldhealth.com)
  • therefore, removal of bacteria in dental biofilms is best achieved by physical disruption - yet this very process contributes to aerosol production. (aeroshieldhealth.com)
  • Actinomyces oris is an early colonizer and has two types of fimbriae on its cell surface, type 1 fimbriae (FimP and FimQ) and type 2 fimbriae (FimA and FimB), which contribute to the attachment and coaggregation with other bacteria and the formation of biofilm on the tooth surface, respectively. (biomedcentral.com)
  • Short-chain fatty acids (SCFAs) are metabolic products of oral bacteria including A. oris and regulate pH in dental plaques. (biomedcentral.com)
  • SCFAs affect the INAC-associated activities of the A. oris fimbrillins and non-fimbrillins during ionized and non-ionized acid formations in the form of co-culturing with other bacteria in the dental plaque but not impact the interaction of A. oris with streptococci. (biomedcentral.com)
  • If not removed regularly, the biofilm undergoes maturation, which is connected with a progressive shift from a Gram-positive to a Gram-negative anaerobic species, which results in formation under the gingival surface, where bacteria grow profusely [ 1 ] . (encyclopedia.pub)
  • The need for retreatment may be attributed to either reinfection by oral bacteria or, more often, to the persistence and regrowth of microorganisms that were not eliminated during the previous treatment. (opendentistryjournal.com)
  • Employment of mechanical instrumentation is the core method for bacterial reduction in the infected root canal, but achieving bacteria-free root canals still proves to be a difficult task [ 3 ]. (opendentistryjournal.com)
  • In patients with AD, oral bacteria were detected in brain tissues, and increased levels of pro-inflammatory cytokines were also detected. (metabiom.org)
  • The oral bacteria observed transiently in blood were broadly citrullinated in the mouth, and their in situ citrullinated epitopes were targeted by extensively somatically hypermutated ACPA B Cells encoded by RA blood plasmablasts. (metabiom.org)
  • The bacterial flora can be classified by Gram staining into Gram-positive and Gram-negative bacteria. (stemcelldaily.com)
  • Endocarditis can be treated with antibiotic therapy and may cause death.Although S. gordonii initiates dental plaque and the colonization of other pathogenic bacteria on tooth surfaces, S. gordonii is not directly pathogenic in the oral cavity. (datapunk.net)
  • There is evidence that removable dental prosthetic constructions serve as a reservoir for oral bacteria and yeast [ 6 ]. (opendentistryjournal.com)
  • These microorganisms all occur naturally in the oral cavity and are normally harmless. (wikipedia.org)
  • What are Commensals of the Oral Cavity? (news-medical.net)
  • Most of the microorganisms that inhabit the oral cavity live in a symbiotic relationship. (news-medical.net)
  • Commensals of the oral cavity keep a close watch on the growth of species which may pose harm to human health. (news-medical.net)
  • Microorganisms present in the oral cavity form a layer on the oral surfaces. (news-medical.net)
  • Fungal infections in the oral cavity can be a result of the growth of fungal biofilms. (news-medical.net)
  • C. Albicans are naturally occurring fungi in the oral cavity but in the presence of unhygienic conditions, it quickly multiplies and grows especially on the hard surfaces like dentures. (news-medical.net)
  • therefore, the current study was designed to assess the efficacy of certain antibiotics, toothpaste, and medicinal plant extracts ( Ajuga bracteosa and Curcuma longa ) versus the bacterial pathogens isolated from the human oral cavity. (scielo.br)
  • Adverse microbial changes, both in composition and function, can act at several levels within the gut (stool and mucosal) and have also been described in the blood and oral cavity. (jci.org)
  • While dysbiosis in the oral cavity could be a source of systemic inflammation, current cirrhosis treatment modalities are targeted toward the gut-liver axis and do not address the oral microbiome. (jci.org)
  • Infections from oral cavity can arise from odontogenic source (common in adults), from tonsil and lymphoid sources (common in children). (drtbalu.co)
  • Infections involving oral cavity usually spread via pathways of least resistance. (drtbalu.co)
  • In all patients with oral cavity infections the threat of mediastinitis should always be considered. (drtbalu.co)
  • These normal commensals reside within biofilms present in the oral cavity. (drtbalu.co)
  • Majority of normal bacterial flora of oral cavity are anaerobes. (drtbalu.co)
  • Oral dysbiosis refers to the imbalance between symbionts and pathobionts in the oral cavity, posing potential threats to host cardiovascular health. (degruyter.com)
  • An essential condition for a microorganism to represent a probiotic of interest for oral health is its capacity to adhere to and colonize various surfaces of the oral cavity. (bvsalud.org)
  • Saliva conains oxygen molecules which is needed to make oral cavity aerobic. (likehealthylife.com)
  • The human oral microbiome refers to an ecological community of symbiotic and pathogenic microorganisms found in the oral cavity. (encyclopedia.pub)
  • The oral cavity is an environment that provides various biological niches, such as the teeth, tongue, and oral mucosa. (encyclopedia.pub)
  • The oral cavity is the gateway between the external environment and the human body, maintaining oral homeostasis, protecting the mouth, and preventing disease. (encyclopedia.pub)
  • Oral cavity and the composition of oral microbiome. (encyclopedia.pub)
  • In the oral cavity, dentilisin not only contributes to gum disease but also triggers other enzymes that promote cancer. (lumoral.com)
  • This connection raises concerns about potential health issues related to dentilisin in the oral cavity, Prof. Sorsa stresses. (lumoral.com)
  • Definition Dental Plaque "is a specific but highly variable structural entity, resulting from sequential colonization of microorganisms on tooth surfaces, restorations & other parts of oral cavity, composed of salivary components like mucin, desquamated epithelial cells, debris & microorganisms, all embedded in extracellular gelatinous matrix. (medicpresents.com)
  • The oral cavity is inhabited by more than 700 microbial species, including fungi and viruses from the respiratory tract. (aeroshieldhealth.com)
  • Conversely, mastication increases saliva flow, with concomitant cleansing of the oral cavity and reduction in malodor. (medscape.com)
  • The human oral cavity is a highly complex ecosystem in which the tooth- and soft-tissue surfaces offer distinct ecological niches for microbial colonization. (biomedcentral.com)
  • Some members of the genera #Porphyromonas , #Prevotella , and #Tannerella are well-known pathogens of the oral cavity, where they can notably cause periodontal disease and dental #Caries . (metabiom.org)
  • One of the most densely populated and diverse sites of the human body is the mouth and gastrointestinal tract (GI tract), which extends from the oral cavity to the anus. (stemcelldaily.com)
  • Acid producing normal flora of the oral cavity such as Lactobacillus acidophilus thrive and may become cariogenic in the presence of high sugar intake and fermentable carbohydrates on the enamel, as from carbonated drinks. (fluoridationaustralia.com)
  • Materials that are used for manufacturing removable prosthesis bases, such as acrylic resins and thermoplastic materials [ 7 - 10 ], interact with the microbiota of the oral cavity and tissues of the prosthetic bed [ 11 - 13 ]. (opendentistryjournal.com)
  • The oral microbiome is susceptible to frequent disruptions caused by the host. (news-medical.net)
  • Cirrhosis development and progression involves several important interorgan communications, and recently, the gut microbiome has been implicated in pathophysiology of the disease. (jci.org)
  • The aim of this review article is to highlight the role of gut microbiome and inflammation in the pathophysiology of cirrhosis and to introduce the oral-gut-liver axis as a new perspective to consider in future research. (jci.org)
  • However, targeting oral microbiome might still provide preventive and therapeutic insights on cardiovascular diseases. (degruyter.com)
  • Moreover, translocation of oral microbes to the intestine aggravates gut microbiome dysbiosis. (degruyter.com)
  • To understand the relationship between our bacterial microbiome and health, it is essential to define the microbiome in the absence of disease. (biomedcentral.com)
  • We describe the bacterial community composition of ten digestive tract sites from more than 200 normal adults enrolled in the Human Microbiome Project, and metagenomically determined metabolic potentials of four representative sites. (biomedcentral.com)
  • The bacterial microbiome of the human digestive tract contributes to both health and disease. (biomedcentral.com)
  • It is therefore critically important to define the microbiome of healthy persons in order to detect significant variations both in disease states and in pre-clinical conditions to understand disease onset and progression. (biomedcentral.com)
  • Experimental evidence shows that the microbiome is needed for the health of the host and that alterations in the ecological equilibrium of microbes can lead to disease. (bvsalud.org)
  • The oral microbiome may play a role in bacterial superinfections and severe complications, such as pneumonia, acute respiratory distress syndrome, and sepsis, which often occur after patients are diagnosed with SARS-CoV-2. (westhoustonperiodontics.com)
  • More research should be performed on bacterial superinfections and their possible connections between the oral microbiome and COVID-19 complications, they wrote. (westhoustonperiodontics.com)
  • Oral Microbiome Related Diseases" Encyclopedia , https://encyclopedia.pub/entry/12380 (accessed December 11, 2023). (encyclopedia.pub)
  • Dysbiosis, or an imbalanced oral microbiome, or ecosystem, can lead to various health issues ranging from common dental problems like cavities and gum disease to severe conditions such as heart disease, Alzheimer's disease, and diabetes. (lumoral.com)
  • Imbalances of the microbiome, also referred to as microbial dysbiosis, could lead to a series of different diseases. (nature.com)
  • We used a metatranscriptomic approach to obtain first insights into the metabolic changes induced by this stress hormone as well as which members of the oral microbiome respond to the presence of cortisol in the environment. (nature.com)
  • Our findings show that the stress hormone cortisol directly induces shifts in the gene expression profiles of the oral microbiome that reproduce results found in the profiles of expression of periodontal disease and its progression. (nature.com)
  • Among the environmental factors that may alter the equilibrium in host-microbiome homeostasis, host-stress is a known risk factor for a variety of diseases. (nature.com)
  • Mouthwashes in COVID-19: Benefit or harm to the oral microbiome? (edu.pe)
  • Identified as a constituent of the oral microbiome by Human Oral Microbiome Database. (datapunk.net)
  • Plaque is rich in species, given the fact that about 1000 different bacterial species have been recognised using modern techniques. (wikipedia.org)
  • Over 700 bacterial species co-inhabit healthy human mouth. (news-medical.net)
  • Around 20 to 30 diverse species were found at a specific site and the ratio varies from 34 to 72 at different oral locations. (news-medical.net)
  • A total of 130 samples were collected from Khyber Teaching Hospital Peshawar, Pakistan, among those 27 species isolated, and eight bacterial species were identified from the samples. (scielo.br)
  • Among all the bacterial species, Staphylococcus aureus (29.62%) and Proteus mirabilis (22.2%) were found to be more prevalent oral pathogens. (scielo.br)
  • Biofilms can be composed of a population that developed from a single species or a community derived from multiple microbial species ( 14 , 17 ). (cdc.gov)
  • Correlation between targeted bacterial species levels from concurrent endodontic-periodontal diseases confirmed that coronal and cervical dentinal tubules may represent a viable pathway that allows spreading and maintaining of dual sites infection. (hoajonline.com)
  • The current article aims to review the beneficial role of some probiotic species, their mode of action and clinical effectiveness especially in periodontal disease and halitosis. (bvsalud.org)
  • The mouth is home to hundreds of bacterial species with various nutritional preferences. (medscape.com)
  • About 80-90% of halitosis is due to intraoral microbial species that populate on the tongue, teeth, and periodontal biofilms. (medscape.com)
  • While some bacterial species are beneficial for dental and overall health, in some cases, they can play a role in the development of serious systemic illnesses. (lumoral.com)
  • Dysbiotic subgingival communities are characterized by a relative increase in abundance of anaerobic, Gram-negative bacterial species that can exploit protein-rich GCF as a nutrient source, promoting development of a proteolytic community phenotype. (biomedcentral.com)
  • 1) Background: The aim of this study was to test whether matrix-bound zoledronate (zol) molecules enhanced the oral biofilm colonization of a mineralized matrix, rendering the alveolar bone more susceptible to medication-related osteonecrosis of the jaw (MRONJ) following invasive dental procedures. (elsevierpure.com)
  • 4) Conclusions: We conclude that matrix-bound zol enhances the oral biofilm colonization of hydroxyapatite. (elsevierpure.com)
  • This is a relevant aspect to take into consideration because microbial adherence to the dentin is the first step in colonization, including tubule invasion, and the origin of biofilm infections. (opendentistryjournal.com)
  • Oral hygiene is important as dental biofilms may become acidic causing demineralization of the teeth (also known as dental caries) or harden into dental calculus (also known as tartar). (wikipedia.org)
  • Early childhood caries (ECC) - dental caries (cavities) occurring in primary teeth up to age 6-years - is a prevalent childhood oral disease with a microbial etiology. (researchsquare.com)
  • Odontogenic infections arise as a result of dental caries (advanced) or from periodontal disease. (drtbalu.co)
  • It can predispose to dental caries due to the presence of bacterial byproducts present within it. (drtbalu.co)
  • Dental caries, periodontal disease and halitosis are among the oral disorders that have been targeted. (bvsalud.org)
  • Caries are common in schoolgoing children and in those who donot maintain proper oral hygiene .Calcium and vitamin deficiency can also predispose caries. (likehealthylife.com)
  • In another report, the maximum concentrations of butyric (8.8 mM), propionic (33.7 mM), acetic (52.6 mM) and formic acids (5.8 mM) were also detected in dental plaques from caries-free and caries-susceptible young subjects [ 32 ]. (biomedcentral.com)
  • It was shown that 40-50% of plaque remains after tooth brushing, and the effects of biofilm retention are clearly evident in the prevalence of caries, gingivitis and periodontal disease. (encyclopedia.pub)
  • To evaluate and assess the relationship between oral health illness perception and caries status among adult dental patients according to variables (age, gender, and presence of dental problems other than dental caries). (wjoud.com)
  • A total of 311 adult dental patients with self-reported dental caries were recruited by systematic random sampling method. (wjoud.com)
  • Oral health illness perception was assessed by using revised illness perception questionnaire for oral health (IPQ-R-OH) and caries status by caries assessment spectrum and treatment (CAST) index. (wjoud.com)
  • Age and presence of dental problems other than dental caries were the significant predictors for illness perception. (wjoud.com)
  • Further, earlier perception of dental caries reduces the progression of the disease and can be prevented. (wjoud.com)
  • Thus, the multiple pathways to the development of dental caries make it difficult to accurately ascertain the contribution of fluoride ingestion to dental caries prevention. (fluoridationaustralia.com)
  • Oral microbiota can act as a storehouse of various respiratory pathogens especially in patients admitted to intensive care units. (news-medical.net)
  • The data obtained through this study revealed that antibiotics were more effective for oral bacterial pathogens than toothpaste and plant extracts which showed moderate and low activity, respectively. (scielo.br)
  • Lačević A, Foschi F, Pojskić L, Pojskić N, Bajrović K and Izard J. Correlation of periodontal pathogens in concurrent endodontic-periodontal diseases . (hoajonline.com)
  • While earlier studies focused on a small number of periodontal pathogens, it is now accepted that the whole bacterial community may be important. (ox.ac.uk)
  • However, many other oral pathogens can play a role in the development of cancer as well. (lumoral.com)
  • Dysbiosis can result in reduced diversity and functionality of the normal flora, increased susceptibility to pathogens or opportunistic infections (such as Clostridium difficile colitis or oral candidiasis), altered immune responses or metabolic disorders (such as obesity or diabetes). (stemcelldaily.com)
  • Dental plaque is also known as microbial plaque, oral biofilm, dental biofilm, dental plaque biofilm or bacterial plaque biofilm. (wikipedia.org)
  • Oral malodor is primarily the result of microbial metabolism. (medscape.com)
  • Studies show that m aintaining a balanced microbial ecosystem in the mouth is crucial for oral health and it has a significant impact on how the body responds to various diseases. (lumoral.com)
  • When the adjacent gingival soft-tissues are inflamed, the flow of serum-like transudate (gingival crevicular fluid, GCF) into the pocket increases and under the influence of this environmental perturbation, homeostasis in the subgingival microbial community can be disturbed giving rise to dysbiosis that predisposes the site to disease [ 3 ]. (biomedcentral.com)
  • More importantly, these microorganisms can even result in serious systemic infections like bacterial endocarditis, preterm labor, pneumonia, and cardiovascular diseases. (news-medical.net)
  • Besides s treptococci, various other microorganisms can also form biofilms at varied sites. (news-medical.net)
  • However, over some time these microorganisms do survive in the presence of various inhibitory actions like brushing, flossing, mastication of food, and swishing with oral disinfectants. (news-medical.net)
  • Oral diseases caused by various microorganisms are common around the world. (scielo.br)
  • The devices become colonized by the microorganisms that form a biofilm of cells, the detachment of which can result in septicemia ( 2 - 5 , 8 , 9 , 14 , 15 ). (cdc.gov)
  • Biofilms are universal, complex, interdependent communities of surface-associated microorganisms. (cdc.gov)
  • Most microorganisms grow in structured biofilms rather than individually in suspensions and while in this environment may display altered phenotypes ( 2 ) . (cdc.gov)
  • Periodontal illness, likewise referred to as gum disease, is an infection brought on by microorganisms, parasites, and infections. (healthdigesthq.com)
  • When microorganisms and healthy proteins from saliva mix with each other, plaque as well as biofilm are created. (healthdigesthq.com)
  • Periodontal disease is caused by a combination of viruses, microorganisms, and parasites. (healthdigesthq.com)
  • Dental plaque is a community of microorganisms found on the surface of teeth or other hard surfaces like dentures and embedded in a matrix of polymers of both host and bacterial origin. (encyclopedia.pub)
  • In summary, the normal flora of the mouth and GI tract is a complex and dynamic community of microorganisms that interacts with the host and the environment, and influences various aspects of human health and disease. (stemcelldaily.com)
  • We manufactured 144 specimens of standardized round shape with a diameter of 10 mm from 4 types of modern polymeric materials used by prosthetic dentistry to produce removable dentures, 12 specimens of each material were placed into suspensions of bacterial cultures of Staphylococcus aureus , Escherichia coli , Candida albicans , then into "ClearaSept" (Test group 1), "Рrotefix active cleanser" (Test group 2), saline solution (Control group), followed by nutrient media. (opendentistryjournal.com)
  • Chronic rhinosinusitis is one of the more common chronic diseases in the United States, and it affects those of all ages. (medscape.com)
  • Polymicrobial infection is generally seen in chronic suppurative otitis media and reflects biofilm in the middle ear space. (idcmjournal.org)
  • Dental plaque, which leads to oral diseases, may be a risk factor causing a severe course of COVID-19 similar to those in above mentioned chronic diseases. (encyclopedia.pub)
  • Translocation can cause systemic infections (such as bacteremia or sepsis), local infections (such as peritonitis or abscesses) or chronic inflammation (such as inflammatory bowel disease or rheumatoid arthritis). (stemcelldaily.com)
  • Antibiotics have not known to penetrate these biofilms. (drtbalu.co)
  • A biofilm is a multilayered microbiological ecosystem that adheres to the surface of a structure and confers greater protection from antibiotics and an immune response vs. the planktonic microbiota alone. (dentistryiq.com)
  • 2 This is most likely due to the fact that the penetration of the antibiotics into the biofilm was low and that there is higher resistance in the biofilm. (dentistryiq.com)
  • 9 Systemic antibiotics help prevent recolonization and reorganization of the biofilm after the biofilm has been disrupted. (dentistryiq.com)
  • The widespread emergence of bacterial resistance to antibiotics has led to the concept of probiotic therapy for application in oral health. (bvsalud.org)
  • Treatment consists of intravenous antibiotic therapy and sometimes oral antibiotics for several weeks. (datapunk.net)
  • As interventions designed to modulate oral dysbiosis may delay progression of cirrhosis, a better understanding of this process is of the utmost importance. (jci.org)
  • Fungal biofilm-associated infections are frequently refractory to conventional therapy because of resistance to antimicrobial agents. (cdc.gov)
  • The use of drugs effective in combating biofilm-associated infections could lead to major developments in the treatment of fungal implant infections. (cdc.gov)
  • Routine oral hygiene practices can disturb these biofilms. (news-medical.net)
  • Maintaining good oral hygiene is the backbone of prevention of many diseases. (news-medical.net)
  • [ 8 ] In people with rigorous oral hygiene, good dentition and a healthy periodontium, the main cause of bad breath (halitosis) is likely to be the back of the tongue. (medscape.com)
  • If oral hygiene is not maintained properly all will suffer from bad breath. (likehealthylife.com)
  • However, previous high-throughput marker gene sequencing studies of supragingival plaque have largely focused on high-income populations with good oral hygiene without including a range of periodontal disease severities. (ox.ac.uk)
  • We recommend that poor oral hygiene be considered a risk to [postviral] complications, particularly in patients already predisposed to altered biofilms due to diabetes, hypertension or cardiovascular disease," they concluded. (westhoustonperiodontics.com)
  • It also emphasizes the crucial role of oral hygiene in promoting overall health. (lumoral.com)
  • This complication arises due to poor oral and prosthesis hygiene, long-term and nocturnal use, smoking, sugar consumption, salivary pH, accumulation of denture plaque, bacterial and yeast contamination of denture surface [ 3 - 5 ]. (opendentistryjournal.com)
  • Intercellular Matrix Accounts for 20% to 30% of the plaque mass Organic and inorganic materials Derived from saliva, gingival crevicular fluid, and bacterial products. (medicpresents.com)
  • The evolution of infections from teeth occurs as follows: Dental diseases gives rise to pulpitis which could progress to periapical abscess which could ultimately spread through bone and soft tissues to involve deeper structures. (drtbalu.co)
  • Many such manifestations of infections associated with the formation of Candida biofilms include those occurring on devices such as indwelling intravascular catheters. (cdc.gov)
  • Biofilm-associated Candida show uniform resistance to a wide spectrum of the currently available conventional antifungal agents, which implies that antimicrobial drugs that specifically target biofilm-associated infections are needed. (cdc.gov)
  • Current and relevant references were selected in order to summarize the studies conducted so far on probiotics in preventing and treating oral infections. (bvsalud.org)
  • Probiotics have proven to be effective in the treatment of several systemic and infectious diseases such as acute diarrhoea, Crohn's disease, cancer, immunodepressive states, inadequate lactase digestion, hyperlipidemia, liver diseases, infections with Helicobacter pylori, genitourinary tract infections and others 12 . (bvsalud.org)
  • Non-blood-borne causes often originate from nasal and upper respiratory tract infections and diseases. (medscape.com)
  • High bacterial loads in the mouth may be the reason why some otherwise healthy patients experience more severe SARS-CoV-2 infections, according to a new article published on June 26 in the British Dental Journal. (westhoustonperiodontics.com)
  • This suggests a possible connection between poor oral health and the severity of SARS-CoV-2 infections, the authors wrote. (westhoustonperiodontics.com)
  • 1-3 Many respiratory infections have been linked to the oral microbiota. (aeroshieldhealth.com)
  • Although direct disease transmission has not been confirmed, oral microflora in healthy and diseased states has been linked to respiratory infections. (aeroshieldhealth.com)
  • Dental surgery, oral trauma, urologic or gynecologic surgery, skin infections and intravenous drug use will increase the chances of endocarditis. (datapunk.net)
  • Besides this, bad breath, infection of the dental roots, and actinomycosis are also listed as some of the other concerns by these biofilms. (news-medical.net)
  • Most manifestations of candidiasis are in fact associated with the formation of Candida biofilms on surfaces, and this phenotype is associated with infection at both the mucosal and systemic sites ( 8 ) . (cdc.gov)
  • One of the most common is oral denture stomatitis, a Candida infection of the oral mucosa promoted by a close-fitting upper denture present in 65% of edentulous persons ( 5 , 8 ). (cdc.gov)
  • Cigarette smoking hinders blood circulation, and also can significantly disrupt the patients' ability to combat the bacterial infection. (healthdigesthq.com)
  • Understanding the risk posed by aerosols will help minimize the possibility of infection transmission during dental procedures. (aeroshieldhealth.com)
  • 9,12,17,19,21 Oral health professionals should be aware of these invisible dangers in the operatory and follow recommended infection prevention protocols before, during and after patient care. (aeroshieldhealth.com)
  • Potential routes of infection in dental settings include direct and indirect contact, inhalation and injections/punctures. (aeroshieldhealth.com)
  • The disease caused by SARS-CoV-2 infection was named Coronavirus Disease 2019 (COVID-19). (encyclopedia.pub)
  • Which diseases are associated with oral microbiota? (news-medical.net)
  • Similar to the effect of gut microbiota on cirrhosis, emerging evidence also suggests that there is a possible link between a dysbiotic oral microenvironment and liver diseases. (jci.org)
  • Some recent evidence also suggests a role of the human oral microbiota in the development of digestive cancer s. (lumoral.com)
  • La majoria d'articles són en anglès, amb alguns en castellà o altres llengües, y la majoria té resum en castellà, gràcies al Biocodex Microbiota Insitute (que no fa els resums en català). (gapsfamily.org)
  • Eventually dental biofilms lead to periodontal disease and dental cavities which are two of the most common diseases in developed nations.S. gordonii also causes bacterial endocarditis by entering the blood stream usually after oral trauma. (datapunk.net)
  • S gordonii is part of the group viridians of Strepotococci, nonpathogenic commensal streptococci, which are integral members of the human oral flora. (datapunk.net)
  • Importantly, oral dysbiosis promotes cardiovascular pathophysiology through different mechanisms. (degruyter.com)
  • Some common mechanisms by which oral dysbiosis increases cardiovascular risks have been illustrated in Figure 1 . (degruyter.com)
  • Dysbiosis of both oral and gut microbiomes result in systemic inflammation and endotoxemia to cause liver dysfunction and even liver diseases (e.g . cirrhosis, nonalcoholic fatty liver disease and nonalcoholic steatohepatitis) [ 4 ]. (degruyter.com)
  • Common mechanisms of oral dysbiosis-promoted cardiovascular pathophysiology. (degruyter.com)
  • Recent studies have revealed that oral dysbiosis may even be involved in the development of life-threatening digestive cancers. (lumoral.com)
  • The recruitment criteria included a set of objective, composite measurements performed by healthcare professionals [ 10 ], defining this reference population and enabling this investigation to focus on defining the integrated oral, oropharyngeal, and gut microbiomes in the absence of host disease. (biomedcentral.com)
  • Adherence of P. gingivalis strains to serum-coated surfaces was studied with confocal microscopy and 2D-gel electrophoresis of bacterial supernatants used to investigate extracellular proteins. (biomedcentral.com)
  • Genera with pathogenic members were well-represented among this disease-free cohort. (biomedcentral.com)
  • There is formation of a thin sticky coating called biofilm on the tongue and oral mucosa. (likehealthylife.com)
  • Previous research has focused mainly on subgingival plaque, but supragingival plaque composition is also known to be associated with disease. (ox.ac.uk)
  • Dental plaque is a biofilm that attaches to tooth surfaces, restorations and prosthetic appliances (including dentures and bridges) if left undisturbed. (wikipedia.org)
  • These organisms colonize tooth surfaces by creating biofilms in the human mouth, also known as dental plaque. (datapunk.net)
  • Soon after establishing multilayered biofilms streptococci establish adhesions on their surfaces. (news-medical.net)
  • Tooth-associated communities were distinct, but not entirely dissimilar, from other oral surfaces. (biomedcentral.com)
  • May involve the interaction of phosphate groups with calcium ions in saliva to form "bridges" Protective functions of early enamel pellicle: protection , lubrication by decreasing frictional forces, may selectively concentrate antimicrobial substances such as immunoglobulins, lysozyme, and cystatins at different oral surfaces. (medicpresents.com)
  • Most of them attach to different surfaces to form some type of biofilm matrix that is highly structured and spatially organized. (encyclopedia.pub)
  • Then the lactic acid that comes from the bacterial fermentation of sucrose and other carbohydrates in the diet reach the enamel surface, which begins to dissolve, releasing Ca and PO 4 ions from the surfaces under the enamel [ 4 ] . (encyclopedia.pub)
  • We assessed a cross-sectional cohort of 962 Malawian women for periodontal disease and used 16S rRNA gene amplicon sequencing (V5 to V7 region) to characterize the bacterial compositions of supragingival plaque samples. (ox.ac.uk)
  • Clearly, bacterial superinfections are common in patients with respiratory diseases such as COVID-19 and pneumonia, but they are not studied enough due in part to diagnostic complexity. (westhoustonperiodontics.com)
  • The direct mechanism is connected with angiotensin-converting enzyme II (ACE-2) receptors, while the indirect mechanism is connected with inflammatory pathways and bacterial superinfections. (encyclopedia.pub)
  • For example, bacterial endocarditis is one such condition that can affect the human heart. (news-medical.net)
  • Clearly, an evolutionary adaptation in one habitat has allowed S. gordoniiand other oral streptococci to invade another habitat .Bacterial endocarditis occurs in humans who most often have artificial heart valves, heart disorders, or hypertrophic cariomyopathy. (datapunk.net)
  • It is curious that oral streptococci are efficient in binding to blood platelets especially since the blood stream is not their natural habitat. (datapunk.net)
  • Recent studies have addressed this phenomenon and concluded that oral streptococci have adapted specialized mechanisms to recognize and bind with sialic-acid containg structures in the mouth, their natural habitat, which also allows for efficient interaction with platelet sialoglycoprotein GPI-alpha, located on the platelet membrane. (datapunk.net)
  • Patients suffering from diabetes, hypertension, obesity, asthma, and kidney and liver disease are in the high-risk group for severe COVID-19 symptoms [ 6 ] . (encyclopedia.pub)
  • Even a thin biofilm can make anaerobic condition favourable for bacterial proliferation. (likehealthylife.com)
  • This is one of the most abundant spirochetes, found in sites with severe periodontal destruction and associated with periodontal disease . (metabiom.org)
  • Examples of such anaerobes include fusobacterium and actinobacteria. (wikipedia.org)
  • S. mutans and other anaerobes are the initial colonisers of the tooth surface, and play a major role in the establishment of the early biofilm community. (wikipedia.org)
  • The bacterial equilibrium position varies at different stages of formation. (wikipedia.org)
  • Check out this medical presentation on Dental Calculus, which is titled "Dental Plaque", to know about the difference between dental plaque, calculus , and materia alba, types of plaque, composition of plaque, and formation of plaque. (medicpresents.com)
  • These biofilms are composed of polysaccharides and it provides the microbes protective environment to reside and proliferate. (drtbalu.co)
  • The digestive tract includes diverse habitats and hosts the human body's greatest bacterial density. (biomedcentral.com)