Bcr. Medical search. Frequent questions

Cite this: BCR Is Unreliable Surrogate for Overall Survival in Prostate Cancer - Medscape - Sep 06, 2023. (medscape.com)
Noutati 2023 BCR prepares the sale of BCR Chișinău S.A. subsidiary to Victoriabank S.A. (victoriabank.md)

Bucuresti, 30 august 2011 - Banca Comerciala Romana (BCR) a acordat si primul bonus de loialitatea clientilor posesori de card Zambet BCR care l-au folosit in perioada mai-iulie 2011. (business-adviser.ro)
Banca Comerciala Romana (BCR), membra a Erste Group, este cel mai important grup financiar din Romania, incluzand operatiunile de banca universala (retail, corporate & investment banking, trezorerie si piete de capital), precum si societatile de profil de pe piata leasingului, managementului activelor, pensiilor private, a bancilor de locuinte si a serviciilor bancare prin telefonul mobil. (business-adviser.ro)
Banca Comerciala Romana (BCR) impreuna cu Transfond au incheiat un parteneriat cu Cheque Dejeuner pentru emiterea facturilor electronice. (business-adviser.ro)
Banca Comerciala Romana (BCR), membra a Erste Group, este cel mai important grup financiar din Romania, incluzand societatile de profil de pe piata leasingului, managementului activelor, pensiilor private si a bancilor de locuinte. (business-adviser.ro)

A significant minority of chronic myeloid leukaemia patients eventually develop resistance to imatinib, often as a result of point mutations within the BCR-ABL kinase domain. (bmj.com)

The BCR was updated in 2018 to reflect new requirements under the EU General Data Protection Regulation and is reviewed annually. (accenture.com)

BCR Chișinău is a subsidiary of Banca Comercială Română (BCR) in the Republic of Moldova, member of Erste Group. (wikipedia.org)

Facilitatea de retragere a numerarului în euro este disponibilă pentru posesorii de carduri de debit BCR persoane fizice la ATM-urile băncii amplasate atât în București, cât și în celelalte mari orașe. (bankingnews.ro)
Pentru clienții BCR care au carduri de debit în lei nu se va percepe un comision de retragere a numerarului, ci doar comisionul de conversie valutară standard. (bankingnews.ro)
Cardul BCR Zambet este primul card de debit contactless din lume, care are inclusa si aplicatia pentru plata transportului in comun. (business-adviser.ro)
La emiterea cardului BCR Zambet, fiecare client primeste cadou 10 lei in portofelul electronic pentru plata calatoriilor. (business-adviser.ro)
BCR este cel mai valoros brand financiar din Romania, dupa gradul de incredere al clientilor si dupa numarul celor pentru care BCR este principala institutie cu care fac banking. (business-adviser.ro)
BCR este banca Nr.1 din Romania pe piata cardurilor si a tranzactiilor bancare, clientii BCR avand la dispozitie cea mai mare retea nationala de ATM - peste 2.000 de bancomate si POS - peste 18.000 de terminale pentru plata cu cardul la comercianti, precum si servicii complete de Internet banking, phone-banking si e-commerce. (business-adviser.ro)
Parteneriatul dintre BCR si TRANSFOND in ceea ce priveste serviciul e-Factur@ continua astfel cea de-a treia directie de dezvoltare in domeniul serviciilor financiare bazate pe infrastructura tehnologica, pe langa serviciile de plati interbancare si linia de urgenta pentru carduri pierdute/furate (serviciul LUC). (business-adviser.ro)

BCR a vandut peste 10.000 de carduri Zambet BCR in primele trei luni de la lansare. (business-adviser.ro)

The abnormal BCR-ABL1 gene is formed when pieces of chromosomes 9 and 22 break off and trade places. (medlineplus.gov)

Accenture's UK BCR was approved in 2021 and since then Accenture has been able to rely on the UK BCR to make data transfers out of the UK. (accenture.com)

As a result, cells expressing different forms of BCR/ABL were recruited for the present study, including K562 (human wild‑type) or TCCY‑T315I (human imatinib‑resistant) and the Ba/F3‑(T315I/E279K/Y253H) (mouse BCR/ABL point mutation‑transfected cells). (spandidos-publications.com)
Interestingly, AVM appeared to be more sensitive to imatinib‑resistant (T315I, Y253H, and E279K) than wild‑type BCR/ABL cells, indicating its potential to overcome imatinib‑resistant severe issues in CML. (spandidos-publications.com)
Thus, cells expressing different forms of BCR/ABL were recruited for the present study, including K562 [human wild-type (WT)] or TCCY-T315I [human imatinib-resistant (IR)] and the Ba/F3-(T315I/E279K/Y253H) (mouse BCR/ABL point mutation-tranfected cells). (spandidos-publications.com)
however, the T315I BCR-ABL mutant has proved resistant to all available TKIs. (bmj.com)
An assay facilitating early identification of BCR-ABL T315I would therefore aid in identifying high-risk patients who may benefit from alternative therapy. (bmj.com)
The data show that Scorpions PCR enables rapid screening for BCR-ABL T315I in chronic myeloid leukaemia patients and is appropriate for use in a clinical setting. (bmj.com)
T315I mutated BCR-ABL is the main cause of the resistance mediated by imatinib and second generation BCR-ABL inhibitor. (jcancer.org)
Here, we determined the effect of Jiyuan oridonin A (JOA), an ent -kaurene diterpenoid compound, on the differentiation blockade in imatinib-sensitive, particularly, imatinib-resistant CML cells with BCR-ABL-T315I mutation by cell proliferation assay, apoptosis analysis, cell differentiation analysis, cell cycle analysis and colony formation assay. (jcancer.org)
We found that JOA at lower concentration significantly inhibited the proliferation of CML cells expressing mutant BCR-ABL (T315I mutation included) and wild-type BCR-ABL, which was due to that JOA induced the cell differentiation and the cell cycle arrest at G0/G1 phase. (jcancer.org)
Mechanistically, the cell differentiation mediated by JOA may be originated from the inhibition of BCR-ABL/c-MYC signaling in CML cells expressing wild-type BCR-ABL and BCR-ABL-T315I. (jcancer.org)

Lista completă a tuturor echipamentelor la care se pot efectua aceste operațiuni bancare este disponibilă pe site-ul BCR. (bankingnews.ro)
BCR are in plan si dezvoltarea optiunii de transmitere a facturii electronice prin intermediul serviciului internet banking catre destinatarii finali", a declarat Valentin Florin Galatanu, directorul executiv al Directiei Tranzactii Bancare din cadrul BCR. (business-adviser.ro)

JOA displayed the activity of inhibiting the BCR-ABL and promoted differentiation of not only imatinib -sensitive but also imatinib -resistant cells with BCR-ABL mutation, which could become a potent lead compound to overcome the imatinib -resistant induced by inhibitors of BCR-ABL tyrosine kinase in CML therapy. (jcancer.org)
BCR-ABL oncogene encodes a BCR-ABL tyrosine kinase (TK), which triggers different downstream targets including c-Myc, STAT5 and CrkL, which participated in the control of cell differentiation, proliferation, migration and other cellular behaviors [ 3 - 5 ]. (jcancer.org)
For most patients with CML, BCR-ABL tyrosine kinase inhibitors (TKIs) have turned the an inevitably fatal disease into a manageable condition. (jcancer.org)
Therefore, imatinib was a paradigm of targeted therapies, which due to that imatinib inhibits the phosphorylation of BCR-ABL then suppress the activation of BCR-ABL tyrosine kinase [ 6 ]. (jcancer.org)

BCR ofera gama completa de produse si servicii financiare prin intermediul unei retele de 48 de centre de afaceri dedicate companiilor si 668 de unitati retail localizate in majoritatea oraselor din intreaga tara cu peste 10.000 de locuitori. (business-adviser.ro)
Cheque Dejeuner este a doua companie din industria tichetelor de masa care se inroleaza in serviciul e-Factur@ pus la dispozitie de Transfond prin intermediul BCR. (business-adviser.ro)

Focusing on preventing BCR-ABL activation is quite efficient, as imatinib has demonstrated, but may not be the optimal option. (spandidos-publications.com)

The ipsogen BCR-ABL1 Mbcr Controls Kit provides high, low, and negative controls for qualitative validation of RNA purification, reverse transcription, and quantitative PCR of BCR-ABL1 Mbcr b2a2 or b3a2 transcripts using real-time PCR on the Rotor-Gene Q and other real-time PCR instruments. (qiagen.com)

BCR Chișinău is one of the first foreign capital owned banks in Moldova, which is a member of an international financial group. (wikipedia.org)
BCR Chișinău started its activity on 22 October 1998 as a universal bank serving both companies and individuals, with a shareholder's capital of 24 million MDL, which was increased further to 728.13 million MDL. (wikipedia.org)
BCR Chișinău serves both companies and individuals. (wikipedia.org)
The unique shareholder of BCR Chișinău is Banca Comercială Română, the biggest financial institution in Romania by total assets, loans and deposits portfolio. (wikipedia.org)
BCR Chișinău management is organized on two levels: executive management - Executive Committee, formed of 3 executive members and supervision - Supervisory Board, formed of 5 members, nonexecutives (are not involved in current company decisions). (wikipedia.org)
Until all approvals are received, BCR Chișinău and Victoriabank will operate independently, after which BCR Chișinău will be integrated into Victoriabank network. (victoriabank.md)
BCR Chișinău has over 13,000 active clients, 110 employees and four branches, two in Chișinău, one in Cahul and one in Bălți. (victoriabank.md)
BCR Chișinău is a solid and performing bank, a model of good governance with quality services and products that bring added value to customers. (victoriabank.md)
I am grateful to my colleagues at BCR Chișinău for all their passion and dedication and for the support they have given to their clients over the years. (victoriabank.md)
For BCR, this decision is part of our strategy to focus exclusively on our business development in Romania, while for all stakeholders - colleagues, customers, and partners - the acquisition of BCR Chișinău by Victoriabank marks the opening of a new ecosystem of partnerships and business synergies. (victoriabank.md)
BCR Chișinău has over 13,000 active customers, and Victoriabank's merger is based on the consolidation and accessibility of the services we offer to our customers, through greater territorial coverage. (victoriabank.md)
Victoriabank and BCR Chișinău have a similar business model, with dedicated products and services both for retail and corporate clients. (victoriabank.md)

The purpose of this kit is to provide the necessary reagents to prepare full length Human TCR and BCR libraries from single cells in combination with a targeted mRNA assay. (bdbiosciences.com)

A BCR-ABL1 genetic test uses a sample of blood or bone marrow to look for an abnormal gene called BCR-ABL1 . (medlineplus.gov)
The abnormal BCR-ABL1 gene is made when two separate genes merge together and become one gene. (medlineplus.gov)
It attaches (fuses) to part of the BCR gene on chromosome 22. (medlineplus.gov)
This makes the abnormal fusion gene, BCR-ABL1 . (medlineplus.gov)
But the abnormal BCR-ABL1 gene has instructions for an abnormal protein. (medlineplus.gov)
An abnormal BCR-ABL1 gene is an acquired genetic change. (medlineplus.gov)
Some medicines target the protein made by the BCR-ABL1 gene. (medlineplus.gov)
If your health care provider thinks you may have a type of leukemia that involves the BCR-ABL1 gene , you may need a BCR-ABL1 genetic test to make a diagnosis. (medlineplus.gov)
An abnormal chromosomal translocation known as t(9;22) results in the establishment of the Philadelphia chromosome, which contains the BCR-ABL gene, culminating in the development of this syndrome ( 1 ). (spandidos-publications.com)
Here, we determined the cooccurrence and independent prognostic relevance of 3 recently identified prognostic features: BCR-ABL1-like gene signature, deletions in IKZF1, and high CRLF2 messenger RNA expression (CRLF2-high). (eur.nl)

The High p210 Control represents a high BCR-ABL p210 transcript level, the Low p210 Control corresponds to a reduced level of p210 expression compared to the high control level, and the Negative BCR-ABL p210 & p190 Control does not contain BCR-ABL p210 transcript. (qiagen.com)

Biochemical recurrence (BCR) falls short as a reliable surrogate for overall survival in localized prostate cancer trials and may not be a suitable primary endpoint. (medscape.com)
In trials of localized prostate cancer, BCR remains a controversial surrogate endpoint for overall survival. (medscape.com)
Prentice criteria and the two-stage meta-analytic approach were used to assess BCR as a surrogate endpoint for overall survival. (medscape.com)
BAFF increased NOTCH2 expression on B cells , augmenting BCR responsiveness to surrogate antigen and NOTCH ligand . (bvsalud.org)

The results revealed that AVM inhibited the phosphorylation of BCR/ABL and their subsequent molecular signals including AKT and MAPK activation. (spandidos-publications.com)

Pana acum, aproape 60% dintre cei care au luat un card BCR Zambet au intre 18 si 35 de ani. (business-adviser.ro)

http://www.publika.md/bcr-chisinau-in-parteneriat-cu-asociatia-businessului-european_947481.html Archived 2016-03-03 at the Wayback Machine 2. (wikipedia.org)

What is a BCR-ABL1 genetic test? (medlineplus.gov)
There are different types of BCR-ABL1 genetic tests. (medlineplus.gov)
Certain types of BCR-ABL1 testing may also be used to help plan treatment for these blood cancers. (medlineplus.gov)
During treatment, BCR-ABL1 tests may be used to see if cancer treatment working. (medlineplus.gov)
Why do I need a BCR-ABL1 genetic test? (medlineplus.gov)
See how well your treatment is working (if treatment is helping, the number of cells with BCR-ABL1 genes will decrease. (medlineplus.gov)
BCR-ABL1 ) quantitative testing is recommended for patients with either chronic myeloid leukemia (CML), a hematopoietic stem cell disease, or acute lymphoblastic leukemia (ALL), an aggressive type of leukemia of either B- or T-lineage immature lymphoid cells. (arupconsult.com)
BCR-ABL1-like, IKZF1-deleted, and CRLF2-high cases constitute 33.7% of BCR-ABL1-negative, MLL wild-type BCP-ALL cases, of which BCR-ABL1-like and IKZF1 deletion (co)occurred most frequently. (eur.nl)
Higher cumulative incidence of relapse was found for BCR-ABL1-like and IKZF1-deleted, but not CRLF2-high, cases relative to remaining BCP-ALL cases, reflecting the observations in each of the cohorts analyzed separately. (eur.nl)
No relapses occurred among cases with CRLF2-high as single feature, whereas 62.9% of all relapses in BCR-ABL1-negative, MLL wild-type BCP-ALL occurred in cases with BCR-ABL1-like signature and/or IKZF1 deletion. (eur.nl)
Both the BCR-ABL1-like signature and IKZF1 deletions were prognostic features independent of conventional prognostic markers in a multivariate model, and both remained prognostic among cases with intermediate minimal residual disease. (eur.nl)
The BCR-ABL1-like signature and an IKZF1 deletion, but not CRLF2-high, are prognostic factors and are clinically of importance to identify high-risk patients who require more intensive and/or alternative therapies. (eur.nl)

Cum pot activa serviciul BCR Alert? (bcr.ro)
BCR claseaza serviciul e-Factur@ in gama produselor cu valoare adaugata oferite clientilor corporate, pozitionand banca intr-o noua etapa in relatia cu clientul. (business-adviser.ro)

BAFF Tg B cells had significantly increased protein levels of the proximal BCR signaling molecule SYK, and high SYK protein was maintained by BAFF after in vitro BCR activation or when alloantigen was present in vivo. (bvsalud.org)
It functions as a negative regulator of CELL PROLIFERATION and NEOPLASTIC CELL TRANSFORMATION and is commonly fused with cellular abl protein to form BCR-ABL FUSION PROTEINS in PHILADELPHIA CHROMOSOME positive LEUKEMIA patients. (bvsalud.org)

It is thus concluded that AVM inhibits the activity of BCR/ABL and their subsequent molecular signals, including AKT and MAPK, resulting in cytotoxicity via apoptosis. (spandidos-publications.com)

Acum poți retrage euro de la bancomatul BCR. (bankingnews.ro)

Pe 30 noiembrie și 1 decembrie , hub-urile BCR vor fi închise, cu excepția celor din mall-uri . (bcr.ro)

https://web.archive.org/web/20120626023550/http://www.bizmedia.md/Banci/BCR-Chisinau-ofera-credite-cu-garantii-din-partea-statului.-VEZI-AICI-cum-e-posibil.html 4. (wikipedia.org)

Chronic myeloid leukemia (CML) results from BCR-ABL oncogene, which blocks CML cells differentiation and protects these cells from apoptosis. (jcancer.org)
Chronic myeloid leukemia (CML) is a clonal expansion of the progenitor hematopoietic stem cells arising from the existence of the fusion BCR-ABL oncogene, that represents 15%-20% of the newly diagnosed cases of leukemia patients [ 1 - 2 ]. (jcancer.org)

Additionally, several resistance mechanisms, such as BCR-ABL genomic amplification, are considered ( 4 ). (spandidos-publications.com)

Retragerile vor fi disponibile începand din luna septembrie la aproximativ 100 de ATM-uri din înteaga țară, urmând ca, până la finele anului, peste 300 de aparate din rețeaua BCR să ofere această facilitate. (bankingnews.ro)
BCR este banca Nr.1 in Romania dupa valoarea activelor (peste 16 mld EUR), banca Nr.1 dupa numarul de clienti si banca Nr.1 pe segmentele de economisire si creditare. (business-adviser.ro)

The trials used different definitions of BCR ― the older American Society of Therapeutic Radiation and Oncology definition, and the more current Phoenix criteria. (medscape.com)
Our findings compel studies of therapeutic targeting of BAFF and BCR pathways in patients with cGVHD. (bvsalud.org)

There was a decrease in ODE-induced lung tissue CD11c+CD11b+ exudative macrophages and compensatory increase in CD8+ T cells in lavage fluid of BCR KO animals. (cdc.gov)

Acasă Business Adviser Comunicate BCR isi consolideaza pozitia de furnizor de servicii de facturare electronica in. (business-adviser.ro)

ODE-induced lymphoid aggregates failed to develop in BCR KO mice. (cdc.gov)

By employing BAFF transgenic (Tg) mice donor cells , we addressed whether high BAFF contributed to BCR activation in cGVHD. (bvsalud.org)

At 48 months, BCR was associated with significantly increased mortality risk: 2.46-fold increased risk for dose escalation, 1.51-fold greater risk for short-term ADT, and 2.31-fold higher risk for ADT prolongation. (medscape.com)

cGVHD manifestations in mice were associated with high BAFF/B- cell ratios and persistence of B- cell receptor (BCR)-activated B cells in peripheral blood and lesional tissue . (bvsalud.org)
B cells and serum immunoglobulins were not detected in BCR KO animals. (cdc.gov)

To comply with these European and UK requirements, Accenture has implemented a set of data privacy rules known as Binding Corporate Rules for Data Controllers (BCR). (accenture.com)
Accenture's EU BCR has been in place since 2009, following an approval process conducted by the European Union data privacy regulators. (accenture.com)
Accenture's Lead Supervisory Authority for the EU BCR is the Irish Data Protection Commission. (accenture.com)
The main objective of this event is to identify differences between the current EU BCRs and the ICO's new UK version, and to take the initiative to encourage the ICO and the European Data Protection Board (EDPB) to have harmonised BCR schemes with mutual recognition in a way that enhances the role of BCRs as a model for global data protection. (privacylaws.com)
In parallel, the EDPB is seeking to refresh its own approach to BCR authorisations in order to hopefully streamline the process further, while in the UK, the Government is looking at the most appropriate model to facilitate international data flows in a way that still provides for the protection of personal data. (privacylaws.com)

BAFF promotes heightened BCR responsiveness and manifestations of chronic GVHD after allogeneic stem cell transplantation. (bvsalud.org)
We demonstrate that pathologic production of BAFF promotes an altered B- cell compartment and augments BCR responsiveness. (bvsalud.org)

CONCLUSIONS: Lung tissue staining for citrullinated and MAA modified proteins were increased in ODE-treated WT animals, but not BCR KO mice. (cdc.gov)

METHODS: Using an established animal model, C57BL/6 wild-type (WT) and B-cell receptor (BCR) knock-out (KO) mice were repetitively treated with intranasal inhalation of swine confinement organic dust extract (ODE) daily for 3 weeks and lavage fluid, lung tissues, and serum were collected. (cdc.gov)

Overall, "these results strongly suggest that BCR-based endpoints should not be the primary endpoint in randomized trials conducted for localized [prostate cancer]," the authors concluded. (medscape.com)
RESULTS: ODE-induced neutrophil influx in lavage fluid was not reduced in BCR KO animals, but there was reduction in TNF-alpha, IL-6, CXCL1, and CXCL2 release. (cdc.gov)

20232

Banca Comerc4

Mutations1

20181

Erste Group1

Pentru7

Carduri1

Chromosomes 9 and 221

20211

T315I10

Bancare2

Tyrosine4

Prin intermediul2

Imatinib1

Ipsogen1

Chișinău12

Assay1

Gene10

P1901

Surrogate4

Phosphorylation1

Dintre1

20161

ABL112

Serviciul2

Protein2

Inhibits1

Acum1

Celor1

Https1

Leukemia2

Resistance1

Peste2

Therapeutic2

Decrease1

Servicii1

Lymphoid1

Activation1

Significantly1

Cells2

Data5

Promotes2

Tissue1

Wild-type1

Results2