• To quantify by meta-analysis the genetic effect of the HLA-B5 or HLA-B51 (HLA-B51/B5) allele on the risk of developing Behçet's disease (BD) and to look for potential effect modifiers. (nih.gov)
  • Additional HLA-B alleles play a smaller role in disease risk: the HLA-B47 and HLA-B51 alleles can contribute to increased risk, whereas the HLA-B7 and HLA-B57 alleles might provide some small amount of protection against developing the condition. (medlineplus.gov)
  • Several versions of the HLA-B gene, particularly HLA-B51 , are associated with an increased risk of developing Behçet disease, a chronic inflammatory condition that affects many parts of the body. (medlineplus.gov)
  • Although many people with Behçet disease have the HLA-B51 variation, most people with this version of the HLA-B gene never develop the condition. (medlineplus.gov)
  • LMF-B51 model of Muffle Furnace is a microprocessor controlled furnace with steel sheet housing material and is efficiently designed for minimal space requirement in the laboratory. (labtron.uk)
  • The B51 is a standard Moto-Lita 9-bolt boss, available in polished or black finish. (moto-lita.co.uk)
  • The strength of the association between BD and HLA-B51/B5, and its consistency across populations of various ethnicities, lends further support to this allele being a primary and causal risk determinant for BD. (nih.gov)
  • Researchers do not know how HLA-B51 increases the risk of this disorder. (medlineplus.gov)
  • B51 or B-51 may refer to: HLA-B51, an HLA-B serotype Bundesstraße 51, a road in western Germany Martin XB-51, an American airplane Sicilian Defence, in the Encyclopaedia of Chess Openings B51 (New York City bus) This disambiguation page lists articles associated with the same title formed as a letter-number combination. (wikipedia.org)
  • The variants of ERAP1 identified in this study increase the risk of Behcet's disease, but only in those individuals with one specific HLA type, HLA-B51, which has previously been associated with Behcet's disease. (nih.gov)
  • 5. [Efficacy of TNF-alpha antagonist and other immunomodulators in the treatment of patients with ophthalmologic manifestations of Behcet's disease and HLA B51 positive vasculitis]. (nih.gov)
  • Several versions of the HLA-B gene, particularly HLA-B51 , are associated with an increased risk of developing Behçet disease, a chronic inflammatory condition that affects many parts of the body. (medlineplus.gov)
  • Although many people with Behçet disease have the HLA-B51 variation, most people with this version of the HLA-B gene never develop the condition. (medlineplus.gov)
  • People with Behçet's disease may have a gene (HLA-B51) that causes a problem in their immune system. (nih.gov)