• Assays can be very diverse, but generally involve the following general steps: Sample processing and manipulation in order to selectively present the target in a discernible or measurable form to a discrimination/identification/detection system. (wikipedia.org)
  • With dye-based detection such as SYBR Green I, primer dimers also affect assay specificity because the nonspecific DNA-binding dye will bind to the primers and be detected along with the desired product. (sigmaaldrich.com)
  • This firm also developed Click-iT EdU Microplate Assay that utilizes nucleoside analog EdU (5-ethynyl-2'-deoxyuridine) and a detection method that does not necessitate DNA denaturation. (news-medical.net)
  • An Enzyme-Linked Immunosorbant Assay (ELISA) for the semi-quantitative detection of IgA antibodies to tissue transglutaminase (endomysium) in human serum. (cdc.gov)
  • The assay, developed by the reference laboratory business of Quest's Focus Diagnostics subsidiary, is intended for the qualitative detection of Zika virus RNA in human serum specimens from certain individuals. (genomeweb.com)
  • If you are interested in a fluorometric detection kit, please check Nitric Oxide Assay Kit (Fluorometric) (ab65327) . (abcam.com)
  • However, data from 2 recently published papers, both of which utilize a new ultrasensitive assay (Simoa) for detecting C. difficile toxins A and B with sub-picogram limits of detection, strongly suggest the opposite. (asm.org)
  • Toxin assay fans could find solace in the exceptionally low limit of detection for toxin, as well as the possibility that perhaps the CDI-NAAT group was too inclusive of patients with low concentrations of toxin that didn't have as many (or any) bad CDI-related outcomes, and thus, were less important to detect. (asm.org)
  • The limit of detection for this assay is provided in the manufacturer's instructions for use and represented by the red lines in the images below (0.63 ng/mL for toxin A and 0.16 ng/mL for toxin B). Line placements are approximate, and the 2 tests were not directly compared. (asm.org)
  • These modified viral nanoparticles were used in immunochromatographic sandwich assays for the direct detection of IgE and of the penicillin-binding protein from Staphylococcus aureus (PBP2a). (nih.gov)
  • The limit of detection of this LFA was 0.13 ng/mL IgE, ∼100 times lower than those of previously reported IgE assays. (nih.gov)
  • The Solana Trichomonas Assay is a rapid in vitro diagnostic test for the qualitative detection of nucleic acids isolated from clinician-collected vaginal swab specimens or urine specimens obtained from asymptomatic or symptomatic patients to aid in the diagnosis of Trichomoniasis. (quidel.com)
  • The Solana Trichomonas Assay, when performed on the Solana instrument, allows for the rapid, accurate detection of Trichomonas. (quidel.com)
  • The assay utilizes helicase-dependent amplification (HDA) and fluorescent probe-based detection in the Solana instrument to determine assay results. (quidel.com)
  • The aim of this study in Egypt was to estimate the usefulness of an interferon-gamma release assay (IFN-γ) assay for the detection of latent TB infection in contacts of active TB cases. (who.int)
  • Thymidine Incorporation Assay BrdU offered by a company Thermo Fisher Scientific includes a nucleoside analog that is identified during active DNA synthesis by employing immunohistochemistry. (news-medical.net)
  • The transwell migration assay (a modification of the classical Boyden chamber assay) is frequently utilized to assess endothelial cell migration, which is one of the main in vitro assays in the repertoire of Thermo Fisher Scientific. (news-medical.net)
  • Thermo Fisher Scientific has launched a predictive assay that, it claims, can assess a drug candidate's potential to cause liver damage earlier than traditional methods. (outsourcing-pharma.com)
  • On the other hand, older generation qualitative assays, especially bioassays, may be much more gross and less quantitative (e.g., counting death or dysfunction of an organism or cells in a population, or some descriptive change in some body part of a group of animals). (wikipedia.org)
  • Among them, in vitro assays have been quantitative and expeditious as initial approximations that warrant further confirmation in vivo . (news-medical.net)
  • This reactivity of chemicals to cutaneous the peptide reactivity assay ( 10 ), quantitative LC-MS was proteins is the basis for most, if not all, current nonanimal- exploited by Natsch et al. (cdc.gov)
  • Today we'll be discussing high-sensitivity troponin assays and how we use them or how we will be using them. (medscape.com)
  • So there is some degree of arbitrariness there, but most of the very high-sensitivity assays detect values in 80% to 100% of people, so it is very likely that those assays are substantially more sensitive. (medscape.com)
  • That said, the increased sensitivity of the assays does cause-for a larger number of patients-an earlier signal. (medscape.com)
  • Well, what's going to happen is that unstable angina , assuming the timing is right to look for a changing pattern of values-which is really key when you have high-sensitivity assays and particularly when we're detecting these other sources for cardiac injury-will go away, and you'll have [non-ST-elevation MI] non-STEMI. (medscape.com)
  • Timed amyloid seeding assay achieves or surpasses sensitivity of currently available tests for transmissible spongiform encephalopathies, according to a report in The Journal of Molecular Diagnostics . (medicalnewstoday.com)
  • A study in The Journal of Molecular Diagnostics describes an advanced assay that offers better sensitivity than currently available tests for detecting a prion disease affecting elk. (medicalnewstoday.com)
  • They compared the sensitivity of the new assay technique, the timed prion seeding assay (tASA), to other currently available tests (two bioassays in laboratory rodents and three commercially available TSE rapid tests). (medicalnewstoday.com)
  • The report describes time specifications for the assay to help avoid false-positive results (30 hours) or false-negative results in weakly-positive samples (48 hours), as well as the number of replications necessary for adequate sensitivity (2-12). (medicalnewstoday.com)
  • There are a number of factors that can be altered to obtain optimum assay performance and thereby lead to higher molecular sensitivity, specificity and precision. (sigmaaldrich.com)
  • Whenever primer dimer products are produced and amplified, they divert reaction components away from synthesis of the desired product, thereby reducing assay efficiency and sensitivity. (sigmaaldrich.com)
  • Davin M. Henderson (Colorado State University) and Carl Peters (BMG LABTECH) talked about how to optimize sensitivity and specifity in the RT- QUiC assay using BMG LABTECH plate readers. (news-medical.net)
  • In March, the FDA granted an EUA to the Trioplex Real-Time RT-PCR Assay , which was developed by the US Centers for Disease Control and Prevention and tests patient samples for Zika, chikungunya, and dengue virus infection. (genomeweb.com)
  • If the assay involves exogenous reactants (the reagents), then their quantities are kept fixed (or in excess) so that the quantity and quality of the target are the only limiting factors. (wikipedia.org)
  • Some reagents for the anti-Xa assay use a patient's own antithrombin, and other reagents add antithrombin exogenously to make a complex of heparin and antithrombin. (medscape.com)
  • Cells and subsequent assay reagents can be dispensed into assay plates using a non-contact, liquid dispenser (Equator™ HTS, Deerac Fluidics ) for accurate pipetting. (genengnews.com)
  • Claims relating to the performance of assays should be verified under the conditions of the study, including test samples, specific reagents and the instrument of choice. (sigmaaldrich.com)
  • However, all assays have a set of optimal conditions and these are dependent on the instrument, selected reagents (buffer conditions), primer concentration and/or annealing temperature (T a ), magnesium concentration and even ramp rate. (sigmaaldrich.com)
  • The Procleix® Ultrio Elite Assay is a qualitative in vitro nucleic acid amplification test to screen for human immunodeficiency virus type 1 (HIV-1) RNA,hepatitis C virus (HCV) RNA, and/or hepatitis B virus (HBV) DNA, and detect human immunodeficiency virus type 2 (HIV-2) RNA in plasma and serum specimens from individual human donors, including donors of whole blood, blood components, and source plasma, and from other living donors. (fda.gov)
  • Therefore in vitro angiogenesis assays should be viewed as a starting point rather than an endpoint for discovery. (news-medical.net)
  • Other in vitro angiogenesis assays that cover all angiogenic functions ( i.e. proliferation, migration, tube formation) include mouse metatarsal assay, embryoid assay and others. (news-medical.net)
  • Research was conducted to compare the results of an enzyme-linked immunosorbent assay (ELISA) to high-performance liquid chromatography (HPLC) for detecting fluometuron in the environment. (bioone.org)
  • Both kits employ the enzyme-linked immunosorbent assay, or ELISA, technique to detect the presence of the protease-resistant form of prion protein-the cause of BSE. (acs.org)
  • The capsid re- gion contained 18 nt substitutions, of which 12 were in the Surveillance Screening Assay VP1 region (online Technical Appendix Table, http://ww- wnc.cdc.gov/EID/article/21/10/15-0702-Techapp1.pdf). (cdc.gov)
  • GPLN) and the World Health Organization's Polio Eradi- screening assay. (cdc.gov)
  • The VDPV assays were found to be 100% specific VDPV screening assay. (cdc.gov)
  • 1 isolate was the VDPV screening assay used in the GPLN. (cdc.gov)
  • ProSpecT Campylobacter Microplate Assay. (fda.gov)
  • A potential contamination was noted in the conjugate in ProSpecT Campylobacter Microplate Assay. (fda.gov)
  • Complex IV Rodent Enzyme Activity Microplate Assay Kit (ab109911) is used to determine the activity of cytochrome c oxidase in a mouse sample with speed and simplicity. (abcam.com)
  • Some assays (e.g., biochemical assays) may be similar to chemical analysis and titration. (wikipedia.org)
  • This homogeneous, bioluminescent assay is easily scalable to 1,536-well plate formats. (genengnews.com)
  • Molecular Devices, at SLAS 2015, launched a homogeneous, no-wash assay to measure ligand- and voltage-gated potassium channel activity. (the-scientist.com)
  • This homogeneous assay is ideally suited for screening applications where assay automation is required. (fishersci.com)
  • An assay that has been designed such that all desirable design criteria were met ( PCR/qPCR/dPCR Assay Design ) is likely to perform well under a wide range of conditions. (sigmaaldrich.com)
  • The primer design can be reviewed with respect to the assay design guidance provided in PCR/qPCR/dPCR Assay Design . (sigmaaldrich.com)
  • A kinetic spectrophotometric assay involving the reactivity of electrophilic sensitizers to nitrobenzenethiol was evaluated. (cdc.gov)
  • 9 ) with the determination of the RC50 value being the marker reactivity of test chemicals as end point toxicology assays have of the potency of a chemical. (cdc.gov)
  • Nitric Oxide Assay Kit (Colorimetric) ab65328 provides an accurate, convenient measure of total nitrate/nitrite in a simple two-step process. (abcam.com)
  • This product is manufactured by BioVision, an Abcam company and was previously called K262 Nitric Oxide Colorimetric Assay Kit. (abcam.com)
  • Although there is a correlation between CDI and very high toxin concentrations, results for the 2 groups of patients are extensively overlapping, and one can see how many patients designated as CDI would be missed by the less sensitive assay. (asm.org)
  • Commercial IGF-I assays may not be fully discriminative of abnormalities in serum IGF-I concentrations in growth-hormone-related diseases," he said. (medscape.com)
  • The CDC Influenza SARS-CoV-2 (Flu SC2) Multiplex Assay is a real-time reverse-transcription polymerase chain reaction (rRT-PCR) laboratory test that can simultaneously detect and differentiate between influenza A, influenza B, and SARS-CoV-2 in upper or lower respiratory specimens. (cdc.gov)
  • Similarly, when multiple targets are to be detected simultaneously in multiplex reactions, assay conditions must be optimized to detect all targets equally. (sigmaaldrich.com)
  • For an assay kit to detect nitrite alone see Griess Reagent Kit ab234044 . (abcam.com)
  • What remains unclear, and is regularly (and at times heatedly) put to debate , is whether less sensitive toxin assays, which detect the actual C. difficile toxin proteins (A and B) that cause CDI, are effective at winnowing out carriage cases and identifying CDI when it really needs to be treated. (asm.org)
  • MARK W. SHANKLE , DAVID R. SHAW , and MICHELE BOYETTE "Confirmation of an Enzyme-Linked Immunosorbent Assay to Detect Fluometuron in Soil," Weed Technology 15(4), 669-675, (1 October 2001). (bioone.org)
  • An assay is an investigative (analytic) procedure in laboratory medicine, mining, pharmacology, environmental biology and molecular biology for qualitatively assessing or quantitatively measuring the presence, amount, or functional activity of a target entity. (wikipedia.org)
  • e.g., pre-analytic steps in medical laboratory assays may contribute 32-75% of all lab errors. (wikipedia.org)
  • Assays purchased from skilled commercial providers still require validation within the laboratory in which they are being used. (sigmaaldrich.com)
  • Laboratory verification of assay quality ensures that the dPCR Copy Number PCR Assays deliver reliable results. (qiagen.com)
  • The new assay can potentially be performed at any CLIA high-complexity laboratory in the Quest Diagnostics network, which includes several dozen labs in the US and Puerto Rico. (genomeweb.com)
  • Get expert-designed custom single or multiplex dPCR and PCR assays. (qiagen.com)
  • dPCR Copy Number Assays are intended for molecular biology applications. (qiagen.com)
  • dPCR Copy Number Assays enable specific, accurate, reproducible and easy-to-interpret copy number change analysis for an individual gene or region of interest. (qiagen.com)
  • Assays for more than 200 targets have been dPCR wet-lab tested. (qiagen.com)
  • The dPCR Copy Number Assays are available in tube format as a ready-to-use 25x-concentrated assay. (qiagen.com)
  • dPCR wet-lab tested assays are flagged as such in the specific assay product view. (qiagen.com)
  • All dPCR Copy Number PCR Assays are designed for unique regions of the human genome. (qiagen.com)
  • The dPCR Copy Number Reference Assays (available separately) include a variety of references with different numbers of copies in the genome, making it possible to select the optimal normalization references for each analysis. (qiagen.com)
  • The dPCR Copy Number Assays are ready to use: just add the DNA sample and mastermix from the QIAcuity EG PCR Kit to the individual assays or reference assays in the QIAcuity Nanoplate. (qiagen.com)
  • To set up the dPCR experiment, add an aliquot of the genomic DNA sample (isolated from fresh, frozen or fixed samples) to the QIAcuity EG PCR Kit mastermix and the dPCR Copy Number Assay. (qiagen.com)
  • dPCR Copy Number Assays are highly suited for accurately detecting copy number alterations or variations at individual loci using DNA from fresh, frozen or fixed samples. (qiagen.com)
  • This rapid extraction process is demonstrated to be compatible with standard inductive coupled plasma mass spectrometry methods for uranium isotopic assay as well as screening techniques such as x-ray fluorescence. (osti.gov)
  • During the COVID-19 pandemic, state public health laboratories can authorize county or city laboratories in their state to perform the SARS-CoV-2 (Flu SC2) Multiplex Assay testing. (cdc.gov)
  • The U.S. Food and Drug Administration (FDA) issued an Emergency Use Authorization (EUA) for use of the Flu SC2 Multiplex Assay on July 2, 2020. (cdc.gov)
  • FDA granted an amendment to the EUA for the CDC Flu SC2 Multiplex Assay to expand the list of extraction instruments that may be used to prepare samples for testing. (cdc.gov)
  • Now, scientists in Argentina have developed a multiplex PCR assay that may simplify the process, and have demonstrated its potential by typing a large set of international samples. (genomeweb.com)
  • In the study published last week in PLoS Neglected Tropical Diseases , Shijman and his collaborators described a multiplex, TaqMan probe-based, real-time PCR assay for the six DTUs. (genomeweb.com)
  • The measured entity is often called the analyte, the measurand, or the target of the assay. (wikipedia.org)
  • We also developed an additional lateral flow assay for IgE, in which the analyte is sandwiched between immobilized anti-IgE antibodies and aptamer-bearing reporter phage modified with HRP. (nih.gov)
  • We introduce the modification of bacteriophage particles with aptamers for use as bioanalytical reporters, and demonstrate the use of these particles in ultrasensitive lateral flow assays. (nih.gov)
  • The assay is based on the principle that cAMP stimulates protein kinase A (PKA) holoenzyme activity, decreasing available ATP and leading to decreased light production in a coupled luciferase reaction (Figure 1). (genengnews.com)
  • Addressing the need to define steadfast analytical performance criteria for prion amyloid seeding assays (ASAs), researchers developed a method to measure prion protein conversion time (from normal cellular form to prion form) by a combination of statistical analyses to obtain a prion-detecting ASA with a known degree of confidence. (medicalnewstoday.com)
  • It is a conversion assay that uses recombinant prion-related protein as a substrate and detects conversion via changes in fluorescence. (medicalnewstoday.com)
  • In general, a DEL has been considered as a massive binding assay to identify physical binders for individual protein targets. (nature.com)
  • An important question in the field of infectious disease diagnostic testing is whether or not Clostridium difficile ( C. difficile ) toxin protein assays (hereafter, toxin assays) differentiate C. difficile infection (CDI) from mere carriage of toxigenic C. difficile in the GI tract. (asm.org)
  • This assay is intended to be used in conjunction with licensed tests for detecting antibodies to HIV-1, HIV-2, HCV, and hepatitis B core antigen, and with licensed tests for hepatitis B surface antigen (HBsAg). (fda.gov)
  • This assay is not intended for use on cord blood specimens. (fda.gov)
  • Since the Mint made no specimens for public sale, these Assay Commission medals have become very collectible and valuable, with some years not known in private collections. (scvhistory.com)
  • The assay measures cAMP levels in cells by monitoring cAMP production in response to the effects of a test compound on GPCRs. (genengnews.com)
  • After the compounds are dispensed into the assay plates, cells of interest are added. (genengnews.com)
  • A majority of endothelial cell assays utilize human umbilical vein endothelial cells or bovine aortic endothelial cells - not because these types of cells are good representatives of vascular conditions in vivo , but primarily because they are relatively easy to harvest from large blood vessels. (news-medical.net)
  • At the moment, the most popular tube formation assays involve plating human umbilical vein endothelial cells or bovine aortic endothelial cells with Matrigel. (news-medical.net)
  • The FLIPR Potassium Assay Kit directly measures potassium channel function using a thallium-sensitive indicator dye that passively diffuses into cells as an acetoxymethyl ester. (the-scientist.com)
  • You can use the media you know, the microplates in which you cultured your cells, and plug these assays into your lab's (or at least a neighboring lab's) existing plate reader. (agilent.com)
  • The problem, which is highlighted ​ in the FDA's critical path initiative, is that liver cells used to test for toxicity lose their activity very rapidly, limiting the amount of assays that can be performed and thereby reducing accuracy. (outsourcing-pharma.com)
  • Review the mitochondrial assay guide , or the full metabolism assay guide to learn about more assays for metabolites, metabolic enzymes, mitochondrial function, and oxidative stress, and also how to assay metabolic function in live cells using your plate reader. (abcam.com)
  • Plates containing confluent 3T3 fibroblasts were exposed to the various media for 24h, at 37°C with 5% CO2, and cell viability was evaluated by a multiparametric assay assessing sequentially, on the same cells, mitochondrial activity (XTT), membrane integrity (neutral red test), and total cell density (crystal violet dye exclusion test). (bvsalud.org)
  • The simultaneous evaluation of different cell viability parameters, in a multiparametric assay, may identify more accurately any possible cytotoxic effects of storage media with immortalized cells intimately related to the in-vivo tissue. (bvsalud.org)
  • In order to sift through today's complex compound libraries, drug developers need high-throughput assays that are easy to use, sensitive, precise, cost-effective, and able to accurately identify promising drug candidates quickly. (genengnews.com)
  • Implementing this miniaturized, high-throughput GPCR assay allows cost-effective screening to identify lead modulators of GPCR signaling. (genengnews.com)
  • The assay achieves this by measuring multiple biomarkers derived from a range of hepatic cell lines simultaneously using Thermo's ToxInsight IVT image cytometry platform. (outsourcing-pharma.com)
  • The information in this article contains billing, coding, or other guidelines that complement the Local Coverage Determination (LCD) for 4Kscore® Assay L36763. (cms.gov)
  • However, assays typically involve biological material or phenomena that are intrinsically more complex in composition or behavior, or both. (wikipedia.org)
  • They then used the new assay to type 307 different biological samples and 39 cultured stocks of T. cruzi . (genomeweb.com)
  • Drug targets of such importance require well-designed assays that can speed up the discovery of novel drug candidates. (genengnews.com)
  • Since it is usual to run the assay on a selected instrument and under standard buffer conditions, most optimization procedures are focussed on modification of primer binding kinetics using primer concentration or annealing temperature (T a )/melting temperature (T m ). (sigmaaldrich.com)
  • Current thallium-based potassium ion channel assays require multiple buffer or media replacements, making them slow and cumbersome, and prone to well-to-well variation. (the-scientist.com)
  • Included in this kit for performance of the activity assay are buffer, detergent, substrate, and 96-well microplate with monoclonal antibody pre-bound to the wells of the plate, allowing for a stream-lined assay. (abcam.com)
  • Assays requiring high specificity are particularly vulnerable when performed without optimization and adequate controls. (sigmaaldrich.com)
  • Positive results obtained with the screens will be confirmed with an immunohistochemistry assay, an expensive test that requires five days for results. (acs.org)
  • An assay usually aims to measure an analyte's intensive property and express it in the relevant measurement unit (e.g. molarity, density, functional activity in enzyme international units, degree of effect in comparison to a standard, etc. (wikipedia.org)
  • This assay is not intended for use as an aid in diagnosis of infection with HIV-1, HIV-2, HCV or HBV. (fda.gov)
  • The assay detected a few mixed infections, but the incidence of mixed infection in patients is actually unknown, since previous typing was usually done from culture, allowing a single DTU to dominate. (genomeweb.com)
  • Plot of C. diff Toxin A concentrations detected using ultra sensitive Simoa assay, in NAAT positive patients, with and without C. diff infection. (asm.org)
  • Subjects diagnosed as latent TB infection by IFN-γ assay (QuantiFERON®-TB Gold In-Tube) were 5.9% of controls, 31.0% of casual contacts and 33.3% of close contacts. (who.int)
  • The most commonly used methodology is the chromogenic assay, which uses a chromophore-linked substrate of factor Xa. (medscape.com)
  • The Western blot assay is a method in which individual proteins of an HIV-1 lysate are separated according to size by polyacrylamide gel electrophoresis. (cdc.gov)
  • R46064 gave false-negative test results cation Initiative (GPEI) accord high priority to detecting because the isolate had a Sabin3 vaccine sequence in the re- all vaccine-derived polioviruses (VDPVs) because they are gions corresponding to the probe and primers of the VDPV neurovirulent and have the potential to cause outbreaks of assay (online Technical Appendix Figure 2). (cdc.gov)
  • Validation of primer design is particularly important when adopting primers from a previous publication or using a commercially supplied assay. (sigmaaldrich.com)
  • USDA had announced in mid-March that it would for the first time use rapid assays in its BSE testing program, which aims to examine brain tissue from 201,000 to 268,000 slaughtered cattle over a 12- to 18-month period ( C&EN, March 22, page 7 ). (acs.org)
  • Cellular metabolism shouldn't be viewed as a complicated workflow, especially with Agilent's new MitoXpress and pH-Xtra assays. (agilent.com)
  • The peptide depletion assay developed skin sensitization perspective, understanding and predicting early by Gerberick et al. (cdc.gov)
  • Similarly, after the assay is completed the results must be documented, verified and communicated-the post-analytic steps. (wikipedia.org)
  • As with any multi-step information handling and transmission system, the variation and errors in reporting final results entail not only those intrinsic to the assay itself but also those occurring in the pre-analytic and post-analytic procedures. (wikipedia.org)
  • NEW YORK (Reuters Health) - Results from six insulin-like growth factor I (IGF-I) commercial immunoassays vary considerably and could result in different classification of patients with growth hormone disorders, according to a cross-sectional assay. (medscape.com)
  • Even when assays give different results, they would be expected to classify a given patient in the same way (high, normal or low values). (medscape.com)
  • These results confirm that, even when using normative values established in the same population of healthy subjects, IGF-I results obtained with different assays in a given individual, whether healthy (as in the VARIETE study), or having a growth hormone-related disorder (as in the present study), are sometimes very different, potentially leading to patient misclassification," the researchers conclude. (medscape.com)
  • It is not possible, according to the results of this study, to recommend one assay or the other," they note. (medscape.com)
  • IGF-I results should be therefore interpreted in an appropriate clinical context, and patient's monitoring during diagnostic work-up and therapeutic management should use the same IGF-I assay. (medscape.com)
  • Indeed, there is a need to increase precision of commercial IGF-I assays, as IGF-I results act as marker of disease and guide future changes in usually costly treatments. (medscape.com)
  • The information sheet describes how the Xpert MTB/RIF assay works, its advantages, how the results should be interpreted, what it means if RIF resistance is detected, not detected, or is indeterminate. (cdc.gov)
  • The factor IX assay is a blood test that measures the activity of factor IX. (medlineplus.gov)
  • Sound energy enables the dispensing of droplets of test compounds in 2.5-nL increments directly from source plates to the assay plates. (genengnews.com)
  • The factor VII assay is a blood test to measure the activity of factor VII. (medlineplus.gov)
  • The researchers will now use this assay for molecular epidemiology, and have published the primer and probe sequences "so everybody can reproduce the test for their own interests," Shijman said. (genomeweb.com)
  • The Bio-Rad kit is the most widely used BSE assay in Europe and is used almost exclusively in Japan to test all its slaughtered animals. (acs.org)
  • Singulex has received the CE mark for its Sgx Clarity cTnI assay, an ultra-sensitive test that measures cardiac troponin at lower levels than most existing assays. (aacc.org)
  • L'objectif de la présente étude conduite en Égypte était d'évaluer l'utilité d'un test de quantification de la libération d'interféron gamma (IFN‑γ) pour le dépistage des infections tuberculeuses latentes chez les contacts de patients atteints de tuberculose active. (who.int)
  • The development of angiogenesis assays was a pivotal step in the discovery of proangiogenic and antiangiogenic molecules. (news-medical.net)
  • In one run of the assay M molecules are tested, generating 2 M N data points. (physicsforums.com)
  • The assay is often repeated multiple times on certain molecules. (physicsforums.com)
  • The most reliable among them calculates proliferation by direct measurement of DNA synthesis, and thymidine incorporation assay is often cited as a reference model. (news-medical.net)
  • The anti-factor Xa assay is designed to measure plasma heparin (unfractionated heparin [UH] and low-molecular weight heparin [LMWH]) levels and to monitor anticoagulant therapy. (medscape.com)
  • Fig. 1: General scheme and key considerations in realizing functional DEL assays. (nature.com)
  • Fig. 5: Strategies for functional DEL assays. (nature.com)
  • Extraction methods enabling faster removal and concentration of uranium compounds for improved trace and low-level assay are demonstrated for standard surface sampling material in support of nuclear safeguards efforts, health monitoring, and other nuclear analysis applications. (osti.gov)
  • Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) Network: NIH Molecular Libraries Screening Centers Network (MLSCN) Grant Proposal Number: MH081277-01 Assay Provider: John C. Reed, Sanford-Burnham Medical Research Institute, San Diego, CA Apoptosis plays an essential role in many aspects of normal development and physiology, becoming dysregulated in myriad diseases characterized by insufficient or excessive cell death. (bindingdb.org)