The routine laboratory findings showed an elevated serum aspartate aminotransferase, alanine aminotransferase, creatine kinase and triglyceride levels. (degruyter.com)
Two markers of cellular metabolism, aspartate aminotransferase (AST) and creatine kinase (CK), were monitored to assess improvements in mitochondrial function. (globenewswire.com)
Horses with increased levels of the muscle enzymes creatine kinase (CK) and aspartate aminotransferase (AST) are the only ones truly tying up. (thehorse.com)
The researchers analyzed the blood for levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatine kinase (CK), and myoglobin (MB), which are associated with exercise-inuduced muscle damage. (nutraingredients.com)
At the end of the experiment, fish fed the modified diet displayed skeletal muscle degeneration, decreased red blood cell count, haemoglobin content and haematocrit, and increased crythrocyte fragility and plasma enzyme activity (aspartate aminotransferase and creatine kinase). (alr-journal.org)
A la fin de l'expérience, les poissons nourris avec l'aliment modifié montrent des lésions de dégénérescence du muscle squelettique, une diminution du nombre de globules rouges, du taux d'hémoglobine et de l'hématocrite, une augmentation de la fragilité érythrocytaire et de fortes activités enzymatiques plasmatiques (aspartate, aminotransferase et créatine kinase). (alr-journal.org)
Serum elevations of ALT activity are rarely observed, except in parenchymal liver disease, since ALT is a more liver-specific enzyme than aspartate aminotransferase (AST). (cdc.gov)
aspartate aminotransaminase (AST), alanine aminotransferase (ALT), based on central laboratory results b. (who.int)
Creatine5
Creatine kinase, aspartate amino-transferase, lactate dehydrogenase and Troponin T were determined by kit methods. (edu.pk)
Creatine kinase (CK), aspartate amino-transferase (AST), lactate dehydrogenase (LDH) were determined by kit methods supplied by Boehringer Mannheim. (edu.pk)
210 blood samples were taken in total, they were centrifuged, and the plasma analyzed of creatine kinase (CK), aspartate transaminase (AST), glucose and lactate. (slu.se)
Damaged muscles release creatine kinase and aspartate transaminase. (finishlinehorse.com)
Measurements of creatine kinase are used in the diagnosis and treatment of myocardial infarction, skeletal muscle diseases, and diseases of the central nervous system. (cdc.gov)
Inhibitor3
U0126 is a potent and selective non-competitive inhibitor of MAP kinase kinase. (rndsystems.com)
Identification of a novel inhibitor of mitogen-activated protein kinase kinase. (rndsystems.com)
3-NP reduced the level of cyclin-dependent kinase inhibitor p27 in striatum but not in cerebral cortex. (nih.gov)
Biosynthesis1
Regulation of aspartate family amino acid biosynthesis in Brevibacterium flavum. (rhea-db.org)
Tyrosine kinase2
Interaction of the tyrosine kinase Pyk2 with the N-methyl-D-aspartate receptor complex via the Src homology 3 domains of PSD-95 and SAP102. (neurotree.org)
Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in chronic phase (CP), previously treated with two or more tyrosine kinase inhibitors (TKIs). (nih.gov)
Histidine-aspartate3
HPts function in histidine-aspartate phosphorelays in which they mediate the signal from sensory kinases (usually membrane proteins) to RRs in the nucleus. (rcsb.org)
Prokaryotes commonly use a histidine-aspartate phosphorelay (HAP) system consisting of a histidine protein kinase (HPK) and a response regulator (RR). (igem.org)
he domain organization of selected histidine-aspartate-phosphorelay systems. (igem.org)
Receptors1
Regulation of calcium/calmodulin-dependent protein kinase II docking to N-methyl-D-aspartate receptors by calcium/calmodulin and alpha-actinin. (neurotree.org)
Aspartokinase1
Aspartate kinase or aspartokinase (AK) is an enzyme that catalyzes the phosphorylation of the amino acid aspartate. (wikipedia.org)
Threonine3
Lysine, threonine, methionine and isoleucine are synthesized from aspartate in a branched pathway in higher plants. (lancs.ac.uk)
Overproduction, purification, and characterization of recombinant bifunctional threonine-sensitive aspartate kinase-homoserine dehydrogenase from Arabidopsis thaliana. (rhea-db.org)
In plant, the first and the third steps of the synthesis of methionine and threonine are catalyzed by a bifunctional enzyme, aspartate kinase-homoserine dehydrogenase (AK-HSDH). (rhea-db.org)
Protein5
Calcium/calmodulin-dependent protein kinase II is associated with the N-methyl-D-aspartate receptor. (neurotree.org)
Protein kinase C regulates human pluripotent stem cell self-renewal. (rndsystems.com)
Specificity and mechanism of action of some commonly used protein kinase inhibitors. (rndsystems.com)
Protein kinase A anchor protein, nuclear localisation signal domain [Interproscan]. (ntu.edu.sg)
Additionally, we detected increased levels of active glycogen synthase kinase 3 β, a physiological kinase of TAU, in neurons derived from AD iPSCs, as well as significant upregulation of amyloid precursor protein (APP) synthesis and APP carboxy-terminal fragment cleavage. (biomedcentral.com)
Phosphorylation1
It demonstrated phosphorylation by the intracellular kinase domain of the cytokinin receptor MtCRE1. (rcsb.org)
NMDA1
Pharmacological experiments revealed that cyclin-dependent kinase activity and N-methyl-d-aspartate (NMDA) receptor were cooperatively involved in cell death by 3-NP in striatal neurons, whereas only NMDA receptor was involved in 3-NP-induced neurotoxicity in cortical neurons. (nih.gov)
Amino1
Aspartokinases are present only in microorganisms and plants, but not in animals, which must obtain aspartate-family amino acids from their diet. (wikipedia.org)
Pathway1
Aspartate kinase plays a key role in the control of the aspartate pathway. (lancs.ac.uk)
Assay2
The enzyme is very sensitive to manipulation and storage and the hydroxamate assay normally used to determine aspartate kinase activity has to be altered according to the plant species and tissue to be analyzed. (lancs.ac.uk)
We have optimized the assay for the determination of aspartate kinase in maize plants callus cell cultures. (lancs.ac.uk)
Muscle1
Parallèlement, de faibles valeurs en DL-alpha-tocophérol et une augmentation des teneurs en substances réagissant à l'acide thiobarbiturique sont observées dans le muscle et le foie. (alr-journal.org)
Activity1
In the case of temperature, 35°C was shown to be the optimum temperature for aspartate kinase activity. (lancs.ac.uk)
Domain4
Dimerisation and phosphoacceptor domain of histidine kinases. (embl.de)
This entry represents the dimerisation and phosphoacceptor domain found in some histidine kinases. (embl.de)
Histidine kinases usually have an N-terminal ligand-binding domain and a C-terminal kinase domain, but other domains may also be present. (embl.de)
These residues form a putative docking interface for either the receiver domain of the sensory kinase, or for the RR. (rcsb.org)
Sequence1
O63067 -- the paper describes a monofunctional hom but the sequence of O63067 is much longer and has a close homolog of functional aspartate kinase (due to alternative splicing? (lbl.gov)
Type1
Les dossiers de 622 patients âgés en moyenne de 58,3 ans (écart type 12,9) ont été étudiés. (who.int)
Patients1
Des stratégies préventives doivent être mises en œuvre afin d'améliorer le pronostic à long terme des patients libyens et de réduire la morbidité et la mortalité globales dues à la coronaropathie. (who.int)