Apoptosis ligands drug screening assays antitumor. Medical search. Frequent questions

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Anatomy29

Cell Line, Tumor Tumor Cells, Cultured Cells, Cultured Cell Line Mitochondria Jurkat Cells HL-60 Cells T-Lymphocytes HeLa Cells Dendritic Cells CD8-Positive T-Lymphocytes Killer Cells, Natural Fibroblasts Epithelial Cells U937 Cells Cell Nucleus K562 Cells T-Lymphocytes, Cytotoxic Macrophages HT29 Cells Cell Line, Transformed CD4-Positive T-Lymphocytes HCT116 Cells CHO Cells Cell Membrane Spleen Lymphocytes Lymphocytes, Tumor-Infiltrating Endothelial Cells

Organisms12

Mice, Nude Mice, Inbred C57BL Mice, Inbred BALB C Mice, Knockout Mice, SCID Mice, Transgenic Adenoviridae Rats, Sprague-Dawley Cricetinae Mice, Inbred C3H Mice, Inbred DBA Oncolytic Viruses

Diseases23

Leukemia P388 Neoplasms Melanoma, Experimental Neoplasms, Experimental Sarcoma 180 Colonic Neoplasms Necrosis Leukemia L1210 Melanoma Lung Neoplasms Disease Models, Animal Breast Neoplasms Prostatic Neoplasms Carcinoma, Lewis Lung Neovascularization, Pathologic Fibrosarcoma Sarcoma, Experimental Adenocarcinoma Liver Neoplasms Carcinoma, Hepatocellular Mammary Neoplasms, Experimental Neuroblastoma Ovarian Neoplasms

Chemicals and Drugs112

Ligands Apoptosis Regulatory Proteins Caspases Caspase 3 Antineoplastic Agents Fas Ligand Protein Proto-Oncogene Proteins c-bcl-2 Inhibitor of Apoptosis Proteins bcl-2-Associated X Protein X-Linked Inhibitor of Apoptosis Protein CD40 Ligand CASP8 and FADD-Like Apoptosis Regulating Protein Apoptosis Inducing Factor Caspase 9 Caspase Inhibitors TNF-Related Apoptosis-Inducing Ligand Caspase 8 Antibiotics, Antineoplastic Tumor Suppressor Protein p53 Membrane Glycoproteins Cytochromes c bcl-X Protein Annexin A5 Enzyme Inhibitors Proto-Oncogene Proteins Antineoplastic Agents, Phytogenic Tumor Necrosis Factor-alpha Cysteine Proteinase Inhibitors Amino Acid Chloromethyl Ketones Poly(ADP-ribose) Polymerases RNA, Messenger RNA, Small Interfering Receptors, TNF-Related Apoptosis-Inducing Ligand Reactive Oxygen Species Recombinant Proteins Membrane Proteins Carrier Proteins Cancer Vaccines NF-kappa B Proto-Oncogene Proteins c-akt Caspase 7 Neoplasm Proteins Cytochrome c Group Recombinant Fusion Proteins Receptors, Tumor Necrosis Factor Doxorubicin RANK Ligand Oligopeptides bcl-2 Homologous Antagonist-Killer Protein Myeloid Cell Leukemia Sequence 1 Protein Proteins Protein-Serine-Threonine Kinases BH3 Interacting Domain Death Agonist Protein DNA-Binding Proteins Antibodies, Monoclonal Staurosporine Indoles Intracellular Signaling Peptides and Proteins DNA Cisplatin Interferon-gamma Mitogen-Activated Protein Kinases Transcription Factors Antigens, CD bcl-Associated Death Protein Ceramides Fas-Associated Death Domain Protein Antigens, Neoplasm Enediynes Cytokines Cysteine Endopeptidases Protein Kinase Inhibitors Etoposide Thiazoles Caspase 2 Phosphatidylinositol 3-Kinases Peptides CD30 Ligand Cyclin-Dependent Kinase Inhibitor p21 Angiogenesis Inhibitors DNA Primers p38 Mitogen-Activated Protein Kinases Camptothecin Imidazoles Pyridines Receptors, Cell Surface Apoptotic Protease-Activating Factor 1 Pyrazines Tumor Necrosis Factors Nuclear Proteins Tumor Suppressor Proteins Interleukin-2 Paclitaxel Caspase 1 Hydrogen Peroxide Plant Extracts Sulfonamides OX40 Ligand Receptors, Death Domain Peptide Fragments Boronic Acids Oligonucleotides, Antisense 4-1BB Ligand Cell Cycle Proteins Adaptor Proteins, Signal Transducing Antigens, CD40 Tetrazolium Salts Growth Inhibitors Receptor, Epidermal Growth Factor Culture Media, Serum-Free Histone Deacetylase Inhibitors MAP Kinase Kinase Kinase 5

Analytical, Diagnostic and Therapeutic Techniques and Equipment34

Drug Screening Assays, Antitumor Xenograft Model Antitumor Assays In Situ Nick-End Labeling Flow Cytometry Blotting, Western Neoplasm Transplantation Transfection Melanoma, Experimental Neoplasms, Experimental Reverse Transcriptase Polymerase Chain Reaction Immunohistochemistry Immunotherapy Transplantation, Heterologous Models, Molecular Models, Biological Lymphocyte Activation Disease Models, Animal Inhibitory Concentration 50 Genetic Therapy Immunotherapy, Adoptive Tumor Burden Immunoblotting Injections, Intralesional Microscopy, Fluorescence Sarcoma, Experimental Antineoplastic Combined Chemotherapy Protocols Mammary Neoplasms, Experimental Oncolytic Virotherapy Drug Evaluation, Preclinical Gene Knockdown Techniques Enzyme-Linked Immunosorbent Assay Binding, Competitive Culture Media, Serum-Free Coculture Techniques

Phenomena and Processes51

Apoptosis Signal Transduction Cell Survival DNA Fragmentation Cell Proliferation Enzyme Activation Dose-Response Relationship, Drug Cell Division Transfection Protein Binding Drug Synergism Cell Cycle Down-Regulation Time Factors Phosphorylation Cell Death Up-Regulation Amino Acid Sequence Binding Sites Gene Expression Regulation, Neoplastic Membrane Potential, Mitochondrial Necrosis DNA Damage Gene Expression Genes, bcl-2 Drug Resistance, Neoplasm Gene Expression Regulation Mutation Molecular Structure Protein Structure, Tertiary Kinetics Lymphocyte Activation Structure-Activity Relationship Inhibitory Concentration 50 Cell Differentiation Base Sequence RNA Interference Cytotoxicity, Immunologic Genetic Vectors Oxidative Stress Cell Growth Processes Cell Movement Protein Conformation Transcription, Genetic Cell Adhesion Cell Cycle Checkpoints Protein Transport MAP Kinase Signaling System Autophagy Binding, Competitive Genes, p53

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science

Ligands Apoptosis Apoptosis Regulatory Proteins Caspases Cell Line, Tumor Caspase 3 Drug Screening Assays, Antitumor Antineoplastic Agents Xenograft Model Antitumor Assays Fas Ligand Protein Proto-Oncogene Proteins c-bcl-2 Inhibitor of Apoptosis Proteins Tumor Cells, Cultured Signal Transduction Cell Survival DNA Fragmentation In Situ Nick-End Labeling bcl-2-Associated X Protein X-Linked Inhibitor of Apoptosis Protein Cell Proliferation Cells, Cultured CD40 Ligand Mice, Nude Mice, Inbred C57BL Cell Line CASP8 and FADD-Like Apoptosis Regulating Protein Apoptosis Inducing Factor Caspase 9 Flow Cytometry Caspase Inhibitors TNF-Related Apoptosis-Inducing Ligand Caspase 8 Antibiotics, Antineoplastic Enzyme Activation Dose-Response Relationship, Drug Mitochondria Tumor Suppressor Protein p53 Membrane Glycoproteins Blotting, Western Mice, Inbred BALB C Cell Division Neoplasm Transplantation Transfection Cytochromes c bcl-X Protein Protein Binding Drug Synergism Cell Cycle Leukemia P388 Annexin A5 Enzyme Inhibitors Neoplasms Proto-Oncogene Proteins Melanoma, Experimental Molecular Sequence Data Antineoplastic Agents, Phytogenic Down-Regulation Neoplasms, Experimental Tumor Necrosis Factor-alpha Sarcoma 180 Time Factors Cysteine Proteinase Inhibitors Jurkat Cells Amino Acid Chloromethyl Ketones Poly(ADP-ribose) Polymerases RNA, Messenger Phosphorylation RNA, Small Interfering HL-60 Cells Cell Death Up-Regulation Mice, Knockout Amino Acid Sequence Receptors, TNF-Related Apoptosis-Inducing Ligand Reverse Transcriptase Polymerase Chain Reaction Reactive Oxygen Species Recombinant Proteins T-Lymphocytes Membrane Proteins Binding Sites Carrier Proteins Gene Expression Regulation, Neoplastic Mice, SCID Cancer Vaccines Colonic Neoplasms Immunohistochemistry NF-kappa B Proto-Oncogene Proteins c-akt Caspase 7 Membrane Potential, Mitochondrial Necrosis Neoplasm Proteins DNA Damage Immunotherapy Mice, Transgenic Adenoviridae Leukemia L1210 Gene Expression Genes, bcl-2 Drug Resistance, Neoplasm

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