• We have developed a DC enrichment platform, which uses the CMRF-44 (IgM) or CMRF-56 (IgG) monoclonal antibodies (mAb) to select BDC that express these antigens after a short overnight incubation. (nih.gov)
  • Assessment of the ability to produce functional antibodies can be obtained by measuring antibody responses to natural antigens or those antigens to which the population commonly is exposed. (medscape.com)
  • Isohemagglutinins are IgM antibodies to ABO blood group antigens that are polysaccharide. (medscape.com)
  • In children who have completed immunizations with diphtheria, pertussis, and tetanus (DPT) or Hib-conjugated vaccines, the antibody response to protein antigens can be tested in adults and older children by measuring IgG antibodies to tetanus or diphtheria toxoid and H influenzae type b (Hib) polysaccharide antigen. (medscape.com)
  • Approximately 80% of children have detectable antibodies to these antigens after 3 immunizations during their first year of life. (medscape.com)
  • Immunogenetics emerged in the 1930s as the study of genes controlling antigens (such as those of the various blood group systems) detected by antibodies. (wikipedia.org)
  • Klein, with his coworker Vera Hauptfeld and his wife Dagmar Klein, were the first to describe the product of the class II genes and identify them as the molecules that control level of antibodies synthesized in response to foreign antigens. (wikipedia.org)
  • Borrelia infections do not only show humoral immune responses by antibodies, but can activate T-lymphocytes at the same time. (arminlabs.com)
  • or actively by prior immunization of the recipient with graft antigens which evoke specific antibodies and form antigen-antibody complexes which bind to the antigen receptor sites of the T-cells and block their cytotoxic activity. (lookformedical.com)
  • Circulating precipitins (antibodies sensitized to antigen) seem not to have a primary etiologic role, and clinical history of allergy (such as asthma and seasonal allergies) is not a predisposing factor. (merckmanuals.com)
  • Expression of Ia and four other plasma membrane antigens was monitored by quantitative binding and radioautographic studies with 125 I-monoclonal antibodies. (rockefeller.edu)
  • For T-cell assays, peripheral blood mononuclear cells cultures were stimulated with vaccinia virus (panels A-C) or cytomegalovirus antigens (panels D-F), and intracellular IFN-γ synthesis was analyzed in CD3(+) T cells. (cdc.gov)
  • The in vitro effects of MSC-Exo on immune cell migration and responder T cell proliferation were examined by chemotactic assays and lymphocyte proliferation assays, respectively. (nature.com)
  • antigens, methods, and interpretation criteria for these assays differ from those for IGRAs approved previously by FDA. (cdc.gov)
  • The Blood TB Test (BTB) is currently based on two assays, a lymphocyte transformation assay and an ELISA to measure antibody formation against antigens (see below). (vin.com)
  • There is, at most, mixed evidence that THC and other cannabinoids are mutagenic in standard microbial assays, such as the Ames test, and there is contradictory evidence on whether the cannabinoids are clastogenic, i.e. produce breaks in chromosomes. (druglibrary.org)
  • ELISPOT assays were used to evaluate the production of IL-1, IL-4, IL-6, IL-10, IL-12 and TNF-α by human monocytes in response to the antigens. (biomedcentral.com)
  • In the transplant population, antigen assays or PCR is used (sometimes in conjunction with cytopathology) for diagnosis and treatment determinations. (medscape.com)
  • Overview of Allergic and Atopic Disorders Allergic (including atopic) and other hypersensitivity disorders are inappropriate or exaggerated immune reactions to foreign antigens. (merckmanuals.com)
  • They act as a surveillance system to detect foreign antigens and shape immunogenic or tolerogenic responses [ 1 ]. (biomedcentral.com)
  • Interferon (IFN)-γ synthesis by T cells after an in vitro stimulation with vaccinia antigens was analyzed in eight healthy donors selected as recently vaccinated, long-term vaccinated, and not vaccinated persons. (cdc.gov)
  • Chromosomal aberrations (hypo- and hyperdiploidy, deletions, breaks, and gaps) in peripheral lymphocytes and bone marrow cells are the predominant effects seen in humans. (cdc.gov)
  • In six patients and six controls allogenic mixed leucocyte reaction (AMLR) was performed using mDC and cord blood-derived naive T cells at a DC/T naive ratio of 1 : 200. (torvergata.it)
  • Moreover, proliferative response of allogenic naive T cells cultured with mDC was impaired in the patients (13471 +/- 9917.2 versus 40976 +/- 24527.2 cpm, P = 0.04). (torvergata.it)
  • The aim of this study was to analyze in vitro the predominance of direct or indirect presentation by depleting antigen-presenting cells in concordant and discordant xenogeneic combinations. (unige.ch)
  • Although dendritic cells (DCs) are the most potent antigen-presenting cells involved in numerous physiologic and pathologic processes, little is known about the signaling pathways that regulate DC activation and antigen-presenting function. (ox.ac.uk)
  • When DCs were fixed, this inhibitory effect of IKK2dn was lost, suggesting that IKK2 is involved in T-cell-derived signals that enhance DC antigen presentation during the allogeneic MLR period and does not have an effect on viability or differentiation state of DCs prior to coculture with T cells. (ox.ac.uk)
  • Finally, we investigated the impact of natural CD25(+) Treg cells on the production of T-helper (Th)1 and Th2 cytokines in mixed lymphocyte cultures between C57BL/6 CD4(+) CD25(-) T cells as responders and bm12 or (C57BL/6X bm12)F1 antigen-presenting cells as stimulators. (ox.ac.uk)
  • Finally, natural CD25(+) Treg cells inhibited the production of interleukin (IL)-2, interferon-gamma, IL-5, and IL-13 in mixed lymphocyte culture in a dose-dependent manner. (ox.ac.uk)
  • NK cells contribute to cancer immune surveillance not only by their direct natural cytotoxicity which is triggered rapidly upon stimulation through germline-encoded cell surface receptors, but also by modulating T-cell mediated antitumor immune responses through maintaining the quality of dendritic cells and enhancing the presentation of tumor antigens. (frontiersin.org)
  • Furthermore, similar to T cells, specific recognition and elimination of cancer cells by NK cells can be markedly enhanced through expression of chimeric antigen receptors (CARs), which provides an opportunity to generate NK-cell therapeutics of defined specificity for cancer immunotherapy. (frontiersin.org)
  • Here, we discuss effects of the GB tumor microenvironment on NK-cell functionality, summarize early treatment attempts with ex vivo activated NK cells, and describe relevant CAR target antigens validated with CAR-T cells. (frontiersin.org)
  • There is experimental evidence from in vitro studies of animal cells that some cannabinoids, including THC, can produce a variety of changes in cellular processes in vitro (i.e. in the test tube). (druglibrary.org)
  • Besides CD19 + CD138 − B cells, plasmablasts, and plasma cells were enriched in the tongue of mice colonized with C. albicans suggesting a potential role of B lymphocytes during oral fungal colonization. (frontiersin.org)
  • Soluble products from antigen stimulated Trypanosoma cruzi-immune spleen cells enhanced the expression of Ia antigens on proteose-peptone-elicited mouse peritoneal macrophages (Mphi). (rockefeller.edu)
  • The levels of three other non-major histocompatibility complex (MHC) antigens, including the trypsin-resistant Fc receptor, were similar in cells exposed to both sources of LK. (rockefeller.edu)
  • Patients were monitored for donor engraftment of myeloid and lymphoid cells, for clinical response by serial imaging, and for immunologic response by in vitro isolation of donor-derived CD8 + CTLs recognizing recipient minor histocompatibility (H) antigens. (aacrjournals.org)
  • Clones from three patients with a partial response or stable disease recognized antigens expressed on renal cell carcinoma tumor cells. (aacrjournals.org)
  • CD8 + CTL-recognizing minor H antigens on tumor cells can be isolated posttransplant and could contribute to the graft- versus -tumor effect. (aacrjournals.org)
  • Azathioprine acts to inhibit purine synthesis necessary for the proliferation of cells, especially leukocytes and lymphocytes. (illnesshacker.com)
  • The aim of our research was to determine how immunotherapy changes the proportion of lymphocyte subsets in dog peripheral blood and the levels of cytokines secreted by these cells during therapy. (mdpi.com)
  • This is due to the fact that certain amino acid sequences, so-called T-cell epitopes, when presented by antigen-presenting cells and recognized by helper T cells, will stimulate a powerful immune response. (genengnews.com)
  • Such peptides are believed to be "promiscuous" T-cell epitopes that bind to the HLA supertypes on the surface of antigen-presenting cells that are broadly represented in the world's population. (genengnews.com)
  • The use of CD20 as suicide gene was investigated in CMV specific T cells and in T cells genetically modified with an antigen specific T-cell receptor. (haematologica.org)
  • 1 , 2 The anti-tumor effect of DLI is mediated by donor T cells recognizing allo-antigens on the malignant cells of the recipient. (haematologica.org)
  • Donor T cells may also induce GvHD due to recognition of allo-antigens on non-malignant tissues of the patient. (haematologica.org)
  • T-cell receptor (TCR) gene transfer is an attractive strategy for rapid in vitro generation of high numbers of antigen specific T cells. (haematologica.org)
  • 4 In addition, TCRs for minor histocompatibility antigens, including HA-1 and HA-2, have been transferred to donor-derived virus-specific T cells to treat patients with hematologic malignancies after allogeneic stem cell transplantation. (haematologica.org)
  • Although human CD20 has previously been described as functional selection marker and suicide gene after retroviral transfer to T lymphocytes, 9 , 10 the specificities of these T cells were unknown, and therefore a potential effect of CD20 on antigen-specific T-cell functions could not be investigated. (haematologica.org)
  • EBV-transformed B cells (EBV-LCL) were cultured in IMDM (Cambrex, Verviers, Belgium) with 10% Fetal Bovine Serum (FBS). (haematologica.org)
  • CD71 antigen expression is low on normal resting lymphocytes and is expressed on all cells upon activation. (nordicmubio.com)
  • Novel surface antigens expressed on dividing cells but absent from non-dividing cells. (nordicmubio.com)
  • Natural killer cells activated in a human mixed lymphocyte response culture identified by expression of Leu-11 and class II histocompatibility antigens. (nordicmubio.com)
  • Intracellular staining of human peripheral blood mononuclear cells (PBMCs) with PCH101 antibody using the anti-human Foxp3 Staining Set and protocol reveals approximately 0.5-4% of lymphocytes staining, with the majority of staining occurring in the CD25^bright population. (thermofisher.com)
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. (thermofisher.com)
  • Endogenous superantigens responsible for inducing strong proliferative responses in T-cells in mixed lymphocyte reactions (see LYMPHOCYTE CULTURE TEST, MIXED). (bvsalud.org)
  • Dendritic cells (DCs) are professional antigen-presenting cells that have multiple subpopulations with different phenotypes and immune functions. (biomedcentral.com)
  • Finally, mononuclear cells isolated from lung (L-MCs), which are used as precursors for L-DCs, expressed more antigen-presenting cell-associated markers such as MHC class II and CD172α compared to their counterparts from blood. (biomedcentral.com)
  • Dendritic cells (DCs) are the most important antigen-presenting cells (APCs) in the body. (biomedcentral.com)
  • Similar results were obtained using biotinylated CMRF-56 mAb, an antibody identifying a comparable population in cultured PBMC. (nih.gov)
  • This assessment can also be done by measuring antibody responses following active immunization with protein or polysaccharide antigens. (medscape.com)
  • Therefore, antibody responses should be measured to polysaccharide antigens that are not present in the protein-conjugated pneumococcal vaccine. (medscape.com)
  • Alternatively antibody response to typhoid-Vi antigen can be measured following typhoid vaccine administration. (medscape.com)
  • The effect of antilymphocyte antibody on lymphocyte transformation. (eurekamag.com)
  • Indirect methods include detection of antigen or antibody, and measures of cellular reactivity against mycobacterial antigen. (vin.com)
  • The immunosuppressive effects of azathioprine involve a greater suppression of delayed hypersensitivity and cellular cytotoxicity tests than of antibody responses. (illnesshacker.com)
  • The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. (bdbiosciences.com)
  • This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. (thermofisher.com)
  • Applications Tested: This PCH101 antibody has been pre-titrated and tested by intracellular staining and flow cytometric analysis using the Foxp3/Transcription Factor Buffer Staining Set (cat. (thermofisher.com)
  • This antibody can be used at 5 µL (0.25 µg) per test. (thermofisher.com)
  • A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. (thermofisher.com)
  • Store undiluted at 4°C. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. (bdbiosciences.com)
  • Transplantation between genetically identical individuals, i.e., members of the same species with identical histocompatibility antigens, such as monozygotic twins, members of the same inbred strain, or members of a hybrid population produced by crossing certain inbred strains. (lookformedical.com)
  • This phase I trial assessed the safety, efficacy, and immunologic responses to minor histocompatibility antigens following nonmyeloablative allogeneic hematopoietic cell transplantation as treatment for metastatic renal cell carcinoma. (aacrjournals.org)
  • Herpes simplex virus thymidine kinase (HSV-tk) is a well-established suicide gene that has been successfully used to control GvHD following donor lymphocyte infusions (DLI) after allogeneic stem cell transplantation. (haematologica.org)
  • As a result, cell proliferation may be inhibited, particularly in lymphocytes and leukocytes. (illnesshacker.com)
  • In vitro studies based on MCF-7 cell proliferation and induction of vitellogenin in primary culture of rainbow trout hepatocytes. (cdc.gov)
  • Bidirectional mixed cultures were performed with lymphocytes from healthy controls and allergic patients with different time periods of IT, and the supernatants obtained from chromatography were tested to determine their effect on IgE synthesis of normal lymphocytes. (cun.es)
  • Suppressor factors derived from allergic patients had no effect on IgE synthesis of normal lymphocytes. (cun.es)
  • Recently, the complete medical oncology field continues to be revolutionized with the launch of immune system checkpoint inhibitors, including T cell VEGFA inhibitory receptors such as for example cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) and designed cell loss of life-1 (PD-1) or its ligand (PDL-1). (nonamimaho.com)
  • Serum was tested for standard neutralization assay. (cdc.gov)
  • Flowcytometry and enzyme-linked immunosorbent assay (ELISA) tests were employed to evaluate subpopulation of T-lymphocytes and the levels of cytokines, respectively. (biomedcentral.com)
  • During her hospitalization,a thorougn evaluation was conducted to determine a possible infectious origin, including blood cultures, urinary antigen tests for L. pneumophila and S. pneumoniae, urine cultures, serum testing for atypical bacteria and major and minor hepatotropic viruses, Quantiferon TB Gold,and enzyme-linked immunosorbent assay (ELISA) for HIV, all of which returned negative results. (medicalandresearch.com)
  • A small aliquot of mycobacterial antigen is injected intradermally and the induration palpated or measured at 48 h (humans) or 72 h (humans, animals). (vin.com)
  • This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. (nordicmubio.com)
  • a dense mixed infiltrate of polymorphonuclear leucocytes, neutrophils, and eosinophils, but few lymphocytes, occupying both papillary and reticular dermis. (jcadonline.com)
  • mDC, derived from peripheral blood monocytes cultured for 6 days in presence of interleukin (IL)-4 and granulocyte-macrophage colony stimulating factor (GM-CSF) and stimulated with lipopolysaccharide (LPS) for the last 24 h, were phenotyped for the expression of the co-stimulatory molecules B7.1 and B7.2. (torvergata.it)
  • Methods that directly detect bacteria from clinical specimens include acid fast and fluorescent smears, culture, and nucleic acid amplification such as polymerase chain reaction (PCR). (vin.com)
  • We showed higher DTH, increased lymphocyte proliferation, decreased tumor growth and reduced JAK2/STAT3 phosphorylation in mice treated with naringenin and CPT. (biomedcentral.com)
  • More recent studies suggested that DCs derived from tissues without "danger" signal stimulation should be regarded as immature DCs, based on their major role in antigen uptake and endocytosis of antigens [ 11 , 14 ]. (biomedcentral.com)
  • Recently, we demonstrated that nuclear factor (NF)-kappaB activation is central to that process, as overexpression of IkappaBalpha blocks the allogeneic mixed lymphocyte reaction (MLR), an in vitro model of T-cell activation. (ox.ac.uk)
  • Quality Assurance also includes testing for sterility, pH, osmolority, presence, or absence of Mycoplasma, endotoxin and presence of Human Leukocyte Antigen (HLA Ag) by Complement Dependent Cellular Cytotoxicity (CDCC) and flow cytometry. (labquip.net)
  • Immunotherapy engages the immune system in the battle against cancer by taking advantage of the capacity of the T lymphocyte for antigen-directed cytotoxicity [ 14 ]. (biomedcentral.com)
  • PHS supports Mixed Lymphocyte Culture (MLC) and Mitogen (PHA) Response. (labquip.net)
  • Les numérations plaquettaire et leucocytaire ainsi que la concentration en cytokines (IL-2R, IL-8 et TNF-) ont été me- surées. (who.int)
  • We also present the data of our own research concerning evaluation of the prognostic role of cytokines and lymphocyte subpopulations in peripheral blood of the TNBC patients. (cttjournal.com)
  • Five patients had progressive disease, two patients had stable disease, and one patient experienced a partial response after receiving donor lymphocyte infusions and IFN-α. (aacrjournals.org)
  • The purified BDC elicited strong allogeneic mixed leukocyte reactions and HLA classes II- and I-restricted antigen-specific primary immune responses. (nih.gov)
  • Ikappa B kinase 2 but not NF-kappa B-inducing kinase is essential for effective DC antigen presentation in the allogeneic mixed lymphocyte reaction. (ox.ac.uk)
  • It is likely that L-DCs play an important role in antigen uptake and processing of respiratory pathogens and are major contributors to respiratory tract immunity and may be ideal tools for future in vitro or ex vivo studies. (biomedcentral.com)
  • Hepatitis B is not a reliable antigen for testing immune competence because of the high frequency of nonresponders in the population, particularly in persons older than 40 years. (medscape.com)
  • These tests give us information about the cellular immune response towards Borrelia antigens. (arminlabs.com)
  • An immune response with both cellular and humoral components, directed against an allogeneic transplant, whose tissue antigens are not compatible with those of the recipient. (lookformedical.com)
  • Cigarette smoking seems to delay or prevent development, perhaps through down-regulation of the lung's immune response to inhaled antigens. (merckmanuals.com)
  • Immune LK selectively enhanced expression of Ia and, to a lesser extent, H-2D relative to control LK from antigen-stimulated noninfected spleen. (rockefeller.edu)
  • For immune defense, the respiratory tract contains DCs that function as a robust antigen presentation system. (biomedcentral.com)
  • Test collection (clean and/or archival tissues, PBMC, serum, plasma, stool, etc.) at particular CP 316311 factors of treatment is certainly important for analyzing feasible biomarkers and learning the systems of responsiveness, level of resistance, relapse and toxicity. (nonamimaho.com)
  • IgE synthesis is controlled not only by antigen-specific mechanism but also by other factors which selectively affect the IgE isotype. (cun.es)
  • Lymphokine enhances the expression and synthesis of Ia antigens on cul" by Ralph M. Steinman, Natalia Nogueira et al. (rockefeller.edu)
  • Azathioprine inhibits DNA synthesis and, as a purine antimetabolite, exerts its effect on activated lymphocytes, which requires purines during their proliferative phase. (illnesshacker.com)
  • Assessment of responses to polysaccharide antigens is important in patients older than 18-24 months because these responses may be deficient in some patients who can respond normally to protein antigens. (medscape.com)
  • Flow cytometric analysis of T-cell responses to smallpox antigens after recent smallpox vaccination and in long-term vaccinated or not vaccinated persons. (cdc.gov)
  • The ability of EpiScreen to detect possible autoimmune responses early on in testing is now well documented. (genengnews.com)
  • The patient was subjected to immunological tests (i.e., purified protein derivative, venereal disease research laboratory, anti-human immunodeficiency virus 1/2, anti-hepatitis B surface antigen, anti-hepatitis B core, anti-Epstein-Barr virus, Chagas [ELISA]) and was diagnosed nonreactive. (jcadonline.com)
  • Polystyrene ELISA or cell culture plates should not be used. (biolegend.com)
  • Transport media are usually not used for throat culture, which is principally performed for bacterial isolation, but are essential for the handling of specimens to identify viral antigens and immunoglobulins. (medscape.com)
  • It may be nonspecific as in the administration of immunosuppressive agents (drugs or radiation) or by lymphocyte depletion or may be specific as in desensitization or the simultaneous administration of antigen and immunosuppressive drugs. (lookformedical.com)
  • Third, if cannabinoids have immunosuppressive effects, then this would have mixed implications for their therapeutic use. (druglibrary.org)
  • 3 Autologous lymphocytes genetically modified with the TCR for MART-1/Melan-A have been adoptively transferred to patients with advanced melanoma. (haematologica.org)
  • in which repeated exposure to antigen in genetically susceptible people leads to acute neutrophilic and mononuclear alveolitis, followed by interstitial lymphocytic infiltration and granulomatous reaction. (merckmanuals.com)
  • Please see Best Protocols Section (Staining intracellular Antigens for Flow Cytometry) for staining protocol (refer to Protocol B: One-step protocol for intracellular (nuclear) proteins). (thermofisher.com)
  • Precipitins were strongly positive against lovebird droppings, but were negative against other avian antigens. (ersjournals.com)
  • The present observation identifies a new causative agent for hypersensitivity pneumonitis and highlights the importance of a thorough environmental history and of searching for precipitins against antigens directly extracted from the patient's environment. (ersjournals.com)
  • LK-induced Ia-bearing Mphi were tested as primary mixed leukocyte reaction stimulators. (rockefeller.edu)
  • Hypersensitivity pneumonitis is a syndrome of cough, dyspnea, and fatigue caused by sensitization and subsequent hypersensitivity to environmental (frequently occupational or domestic) antigens. (merckmanuals.com)
  • Over 300 antigens have been identified as triggers for hypersensitivity pneumonitis. (merckmanuals.com)
  • in farmers, in whom chronic bronchitis is far more common, occurs independently of smoking status, is linked to thermophilic actinomycete exposure, and leads to findings similar to those of hypersensitivity pneumonitis on diagnostic testing. (merckmanuals.com)
  • causes dyspnea in people previously sensitized to an inhaled antigen, but features such as airflow obstruction, airway eosinophilia, and differences in triggering antigens distinguish it from hypersensitivity pneumonitis. (merckmanuals.com)
  • Hypersensitivity pneumonitis (HP) is an immunologically mediated lung disease due to the repetitive inhalation of antigens. (ersjournals.com)
  • Hypersensitivity pneumonitis (HP) is an immunologically mediated lung disease caused by inhaled antigens that provoke lymphocytic inflammation and granulomatous lesions in the peripheral airways and surrounding interstitium. (ersjournals.com)
  • A: "At the moment, there are cellular based tests on the market. (arminlabs.com)
  • If a large amount of cellular material is seen in the transport medium (cloudy appearance), the specimen is centrifuged for 5 minutes at full speed and the supernatant used for tissue culture inoculation. (medscape.com)
  • The only truly effective treatment is early recognition of the causative antigen and control of exposure. (ersjournals.com)
  • Genetic mapping of the loci controlling the class I and class II antigens of the mouse showed them to be part of a cluster, which Klein mapped to the chromosome 17 and for which he championed the name major histocompatibility locus, Mhc. (wikipedia.org)
  • They are encoded by mouse mammary tumor viruses that have integrated into the germ line as DNA proviruses (MINOR LYMPHOCYTE STIMULATORY LOCI). (bvsalud.org)
  • In this study, we tested the effect of local administration of human MSC-Exo on established EAU in the same species. (nature.com)
  • HIV-1 Vif appears to be required in the course of the late levels of virus manufacturing for the suppression of an innate antiviral phenotype that resides in human T lymphocytes . (hoxyl.pl)
  • We investigated the use of human CD20 as suicide gene in T-lymphocytes. (haematologica.org)
  • It has been suggested that cytokine acc leukoreduction prevents transmission of cyc cumulation in plasma of platelet concenc tomegalovirus and decreases alloimmunizac trates (PC) during storage may contribute tion to human leukocyte antigen (HLA), it to development of nonchaemolytic febrile does not prevent allergic reactions. (who.int)
  • All patients achieved initial mixed hematopoietic chimerism with two patients rejecting their graft and recovering host hematopoiesis. (aacrjournals.org)
  • 5 - 8 A drawback of TCR gene therapy is the formation of mixed TCR dimers, consisting of transgenic and endogenous TCR α and β chains. (haematologica.org)
  • Borrelia burgdorferi LFA-1 (Lymphocyte Function Antigen 1): Own body protein + Borrelia burgdorferi sensu stricto (shared epitope). (arminlabs.com)
  • Although acid fast smears of clinical specimens or histologic examination of tissues can detect mycobacteria, species identification requires either confirmation by culture or DNA probes. (vin.com)
  • Lymphocyte transformation is measured by incubating lymphocytes with mycobacterial antigens, typically 1 µg of PPD derived from M. bovis, in the presence of radiolabeled thymidine (a nucleic acid precursor). (vin.com)
  • It seems that these tests will be used in the future, apart from serological tests. (arminlabs.com)
  • Depending on the phylogenetic disparity, direct or indirect antigen presentation is predominant. (unige.ch)
  • Each unit is tested and found negative for: HBsAg, HCV, HIV-1, HIV-2, HIV-1Ag or HIV 1-NAT, ALT, and syphilis by FDA-Approved Methods. (labquip.net)
  • This material was tested and found to be non-reactive for hepatitis B Surface Antigen (HBsAg), Anti-HIV and Hepatitis C. (labquip.net)