• Sixty-five microorganisms were isolated, among which 56.9% were coagulase-negative Staphylococcus, 26.2% were Gram-negative bacilli, 7.7% were Enterococcus faecalis, and 6.2% were Candida parapsilosis. (bvsalud.org)
  • Thereafter, their antimicrobial properties against Enterococcus faecalis, Staphylococcus epidermidis, and Staphylococcus aureus (clinical and reference strains) were analyzed in the dark and after exposure to visible light (VIS). (bvsalud.org)
  • Antimicrobials used in food industries, bio-preservatives or antibacterial peptides like Nisins, pediocin, mersacidin, mutacin and lactacin have proved to be active against Vancomycin Resistant Enterococci and Methecillin Resistant Staphylococcus aureus strains, have instance of potential therapeutic strategy to kill bacterial infections and multidrug-resistant bacteria (Papagianni and Anastasiadou, 2009, Nishie et al. (bbrc.in)
  • Staphylococcus aureus is a Gram-positive spherically shaped bacterium , a member of the Bacillota , and is a usual member of the microbiota of the body, frequently found in the upper respiratory tract and on the skin . (mdwiki.org)
  • Furthermore, the immobilization of LF to mucosal surfaces containing sulfated glycans such as heparan sulfate or its closely related analogs, including galactose-rich polysaccharide (a water-soluble fraction from agar) and carrageenans, were found to enhance the antimicrobial spectrum of LF multi-fold. (ift.org)
  • The 5D Health Protection Group Ltd commits to developing new antimicrobial and antibiofilm agents by 2022. (cdc.gov)
  • These new antimicrobial and antibiofilm technologies will treat wound and medical device related infections, and will provide an alternative treatment to antibiotic classes in which bacterial resistance is high. (cdc.gov)
  • Herein, we present mercaptophenylboronic acid (MBA)-modified gold nanoclusters with well-defined molecular formulas and structure (Au44(MBA)18) and excellent antibacterial activities against various drug-resistant bacteria such as vancomycin-resistant Enterococcus faecalis (VRE). (bvsalud.org)
  • Recent trends suggest that if an effective alternate to antibiotics is not found quickly then the very existence of mankind could come under threat .The safety profile of bacteriocins is much superior to antibiotics. (bbrc.in)
  • The CDC estimates that up to 70% of human bacterial infections in the Western world are caused by biofilms. (joyfulpetlife.com)
  • Patients with biofilm-based infections can heal, but poor nutrition, oxygenation or blood perfusion, or white cell dysfunction, can prevent healing. (joyfulpetlife.com)
  • Note: The National Institutes of Health estimates that 80% of refractory infections in both humans and animals are attributable to biofilm colonies. (joyfulpetlife.com)
  • Acitenobacter baumannii is resistant to aminoglycosides and is responsible for many serious infections found in hospital settings. (joyfulpetlife.com)
  • Although biofilms are a normal occurrence, they can also be harmful to both humans and animals. (joyfulpetlife.com)
  • Biofilms are part of the normal complement of microbes in many healthy animals. (joyfulpetlife.com)
  • Acetyl-11-keto-β-boswellic acid (AKBA), which exhibited the most potent antibacterial activity, was further evaluated in time kill studies, mutation prevention frequency, postantibiotic effect (PAE) and biofilm susceptibility assay against oral cavity pathogens. (biomedcentral.com)
  • The current research targeting microbial biofilm inhibition has attracted a great deal of attention, and the search for effective antimicrobial agents against these oral pathogens could lead to identification of new agents for the prevention of dental caries and periodontal diseases arising out of dental plaque formation [ 6 ]. (biomedcentral.com)
  • Bacterial biofilm formation is a major persistent threat, as it increases morbidity and mortality, thereby imposing heavy economic pressure on the healthcare sector. (frontiersin.org)
  • Bacterial biofilms also strengthen biofouling, affecting shipping functions, and the offshore industries in their natural environment. (frontiersin.org)
  • The development of intact biofilms is very critical for the spreading and persistence of bacterial infections in the host. (frontiersin.org)
  • Therefore, this review discusses the current understanding of antibiotic resistance mechanisms in bacterial biofilm and intensely emphasized the novel therapeutic strategies for combating biofilm mediated infections. (frontiersin.org)
  • Bacterial biofilms can attach to various materials such as metals, glass surfaces, plastic wares, tissues, and clinical devices. (frontiersin.org)
  • Bacterial biofilms housing dormant persister cells are innately tolerant to antibiotics and disinfectants, yet several membrane-active agents are known to eradicate tolerant bacterial cells. (nih.gov)
  • Therefore, biofilms are more often associated with a lower sensitivity of bacterial cells to antibiotics, resulting in prolonged infections and the development of AMR [ 17 ]. (springeropen.com)
  • The advent of novel strategies for treating and preventing biofilm formation has gained a great deal of attention. (frontiersin.org)
  • The forthcoming experimental studies will focus on these recent therapeutic strategies that may lead to the development of effective biofilm inhibitors than conventional treatments. (frontiersin.org)
  • Biofilm formation is a major concern in various sectors and cause severe problems to public health, medicine, and industry. (frontiersin.org)
  • This stimulated research is a rapidly growing field for applicable control measures to prevent biofilm formation. (frontiersin.org)
  • Furthermore, AKBA inhibited the formation of biofilms generated by S.mutans and Actinomyces viscosus and also reduced the preformed biofilms by these bacteria. (biomedcentral.com)
  • It is a key contributor to the formation of biofilms associated with dental caries disease. (biomedcentral.com)
  • We tested our panel of membrane-active agents against MRSA stationary cultures and found 1 to rapidly eradicate MRSA stationary cells by 4 log units (99.99 %) in 30 min. (nih.gov)