Treatment for AA typically involves off-label use of topical, intralesional, and systemic corticosteroids as well as non-steroidal treatments such as topical immunotherapy, topical minoxidil, topical irritants such as anthralin, and systemic immunosuppressants such as cyclosporine or methotrexate [ 3 ]. (springer.com)
Treatment is with combinations of drugs applied topically, taken orally, or injected into the scalp and can include corticosteroids, anthralin, minoxidil, topical immunotherapy (ie diphenylcyclopropenone), or systemic immunosuppressants. (msdmanuals.com)
Effects of anthralin4
The aims of the present study were to investigate the effects of anthralin on hair growth in balding C3H/HeJ mice affected by an AA-like disease and to study the underlying mechanisms. (unboundmedicine.com)
It appears that anthralin may be an effective therapy for C3H/HeJ mice with AA and certain cytokines may be involved in the therapeutic effects of anthralin on restoring hair regrowth in AA-affected C3H/HeJ mice. (unboundmedicine.com)
However, numerous studies have demonstrated antiproliferative and anti-inflammatory effects of anthralin on psoriatic and normal skin. (globalrph.com)
The anti-proliferative effects of anthralin appear to result from both an inhibition of DNA synthesis as well as from its strong reducing properties. (globalrph.com)
Antipsoriatic2
Modification of bases in calf thymus DNA by treatment with the antipsoriatic drug anthralin was studied. (uni-regensburg.de)
In particular, 1,8-Dihydroxy-9,10-anthraquinone is the precursor for the important topical antipsoriatic drug anthralin, 1,8-dihydroxy-9-anthrone, There are 28 ways of choosing two of the 8 possible hydrogens, but because of the four-fold symmetry of the 9,10-anthraquinone core there are only 10 distinct isomers. (wikipedia.org)
Coal tar1
Ointments such as coal tar, anthralin, non-steroidal vitamin D3 (calcipotriol), and steroid creams are also useful. (pediatriconcall.com)
Zithranol Shampoo contains 1% anthralin in a shampoo base containing glyceryl monolaurate, glyceryl monomyristate, citric acid, sodium hydroxide, FD&C Blue #1, Macare® G-2C, and purified water. (globalrph.com)
Zithranol Shampoo (anthralin 1%) microcrystalline-encapsulated system is supplied in tubes. (globalrph.com)
Use of Zithranol Shampoo is contraindicated in patients who are hypersensitive to anthralin or to any ingredient in this preparation. (globalrph.com)
Usually prescribed as a topical cream or shampoo, anthralin can also help clear away scaly skin and smooth skin. (sesamecare.com)
Ointment1
Affected C3H/HeJ mice were treated daily for 10 weeks on half of the dorsal skin with 0.2% anthralin and the contra-lateral side was treated with the vehicle ointment. (unboundmedicine.com)
Structural1
A variety of structural analogues of anthralin were also tested at 75 μM and were either weaker or stronger hydroxylating agents. (uni-regensburg.de)
Irritation1
After 20 to 60 minutes, anthralin is washed off to avoid skin irritation. (dermadvance.gr)
Treatment2
An RNase protection assay (RPA) showed that expression of tumor necrosis factor-alpha (TNF-alpha) and -beta were inhibited by anthralin upon successful treatment. (unboundmedicine.com)
Treatment of calf thymus DNA with anthralin significantly enhanced the amount of modified bases above control levels. (uni-regensburg.de)
Cell growth1
Anthralin is a man-made tar that is used to slow skin cell growth. (sesamecare.com)
Avoid1
Follow your doctor's directions when using anthralin to avoid adverse effects or staining. (sesamecare.com)
Action1
The pharmacological implications of these characteristics of the action of anthralin on DNA bases are discussed. (uni-regensburg.de)
Dithranol3
Tretinoin and anthralin/dithranol used concurrently with Rogaine may increase its absorption. (umc-cares.org)
After that, an anthralin (dithranol) treatment with a contact time of 20 minutes is used. (thermalhotelharkany.eu)
Dithranol (also called anthralin) is derived from synthetic drug Chrysarobin. (thepsoriasisprogram.com)
Topical anthralin1
2. Fluorescence remission spectroscopy of psoriatic lesions and the effect of topical anthralin therapy. (nih.gov)
Retinoids1
Other topical therapies include vitamin D-based medicines, retinoids (related to vitamin A), coal tar, anthralin (another tar product), phosphodiesterase 4 (PDE4) inhibitors, and medicines activating the aryl hydrocarbon receptor (AhR). (nih.gov)
Doctor's1
Follow your doctor's directions when using anthralin to avoid adverse effects or staining. (sesamecare.com)
Messy2
Disadvantages of using Anthralin are that it is messy and can stain clothing and skin. (healthy-skincare.com)
Tar and Anthralin are old and messy, but they work. (uchicago.edu)
Medicines1
Other medicines when if new hair growth from anthralin application happens, it is usually visible within eight to 12 weeks. (hewedi.com)
Skin2
Anthralin is a man-made tar that is used to slow skin cell growth. (sesamecare.com)
Anthralin can irritate the skin, so it is usually applied to the affected skin and then washed off after a prescribed period of time. (sesamecare.com)
Drug1
In particular, 1,8-Dihydroxy-9,10-anthraquinone is the precursor for the important topical antipsoriatic drug anthralin, 1,8-dihydroxy-9-anthrone, There are 28 ways of choosing two of the 8 possible hydrogens, but because of the four-fold symmetry of the 9,10-anthraquinone core there are only 10 distinct isomers. (wikipedia.org)
Hair loss1
The hair loss is being treated with anthralin, which causes the brownish hyperpigmentation and can induce hair regrowth. (mountsinai.org)