Stephania contains tetrandrine, a potent smooth muscle relaxant. (wikipedia.org)
The root contains many isoquinoline alkaloids: tetrandrine (0.6-0.9%), fangchinoline (0.5%), cyclanoline (0.1%) and dimethyltetrandrine iodide (muscle relaxant). (wikipedia.org)
The main active alkaloids are: tetrandrine (12 to 23 grams/kg) and fangchinoline (0.3-3 mg/kg). (wikipedia.org)
3. Tetrandrine and fangchinoline, bisbenzylisoquinoline alkaloids from Stephania tetrandra can reverse multidrug resistance by inhibiting P-glycoprotein activity in multidrug resistant human cancer cells. (nih.gov)
10. Simultaneous determination of tetrandrine and fangchinoline in herbal medicine Stephania tetrandra S. Moore by liquid chromatography with electrochemical detection. (nih.gov)
11. Natural Bis-Benzylisoquinoline Alkaloids-Tetrandrine, Fangchinoline, and Cepharanthine, Inhibit Human Coronavirus OC43 Infection of MRC-5 Human Lung Cells. (nih.gov)
17. An overview on the chemistry, pharmacology and anticancer properties of tetrandrine and fangchinoline (alkaloids) from Stephania tetrandra roots. (nih.gov)
19. Ultra high performance liquid chromatography with tandem mass spectrometry method for the determination of tetrandrine and fangchinoline in rat plasma after oral administration of Fangji Huangqi Tang and Stephania tetrandra S. Moore extracts. (nih.gov)
Tetrandrine, an alkaloid from S. tetrandra exhibits anti-hypertensive and sleep-enhancing effects in SHR via different mechanisms. (bvsalud.org)
A plant species of the genus STEPHANIA , family MENISPERMACEAE , that contains tetrandrine and bisbenzylisoquinoline alkaloids. (nih.gov)
Fangchinoline1
1. Anti-hyperglycemic effect of fangchinoline isolated from Stephania tetrandra Radix in streptozotocin-diabetic mice. (nih.gov)
Moore3
6. Therapeutic efficacy of Stephania tetrandra S. Moore for treatment of neovascularization of retinal capillary (retinopathy) in diabetes--in vitro study. (nih.gov)
18. Inhibitory effects of Stephania tetrandra S. Moore on free radical-induced lysis of rat red blood cells. (nih.gov)
Furthermore, total alkaloids from Stephania tetrandra S. Moore, total flavonoids from Astragalus mongholicus Bunge and total flavonoids from Glycyrrhiza uralensis Fisch. (doctorpenguin.com)
Menispermaceae1
Stephania tetrandra is a herbaceous perennial vine of the family Menispermaceae native to China and Taiwan. (wikipedia.org)
Radix1
14. Synergistic Inhibition of Acetylcholinesterase by Alkaloids Derived from Stephaniae Tetrandrae Radix, Coptidis Rhizoma and Phellodendri Chinensis Cortex. (nih.gov)
Plant1
Then a scientist was able to synthesize or copy this plant alkaloid into a chemical drug without using the original tree bark for manufacturing the drug. (rain-tree.com)
Structure2
13. Comprehensive profiling of Stephania tetrandra (Fangji) by stepwise DFI and NL-dependent structure annotation algorithm-based UHPLC-Q-TOF-MS and direct authentication by LMJ-HRMS. (nih.gov)
The alkaloids whose structure has been established to the present all belong to steroidal alkaloids of pregnane type. (go.jp)