• locus
  • 1992. Molecular characterization of the mouse agouti locus. (jax.org)
  • Black horses were created with a modification of the agouti locus. (wikipedia.org)
  • The alleles at the B locus are related to the production of tyrosinase related protein 1 (TYRP1) and determine the degree to which an animal expresses tyrosinase, an enzyme related to the production of melanin, in its coat and skin (including the nose and paw pads). (wikipedia.org)
  • inhibitor
  • The motif is also found in some inhibitor proteins found in plants, but the plant and animal motifs are thought to be a product of convergent evolution. (wikipedia.org)
  • polypeptide
  • POMC is synthesized in the pituitary from the 285-amino-acid-long polypeptide precursor pre-pro-opiomelanocortin (pre-POMC), by the removal of a 44-amino-acid-long signal peptide sequence during translation. (wikipedia.org)
  • This invention relates to peptide analogs of agouti polypeptide and agouti-related polypeptide that are useful in modulating feeding behavior. (google.com)
  • The agouti gene was cloned in 1992 and was found to encode a 131 amino acid polypeptide (Bultman et al. (google.com)
  • The corresponding human polypeptide is 132 amino acids in length, and is about 25 percent identical to human agouti polypeptide. (google.com)
  • motif
  • The ICK motif is a very stable protein structure which is resistant to heat denaturation and proteolysis. (wikipedia.org)
  • primarily
  • Agouti-related protein is expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with lower levels of expression in the testis, kidneys, and lungs. (wikipedia.org)
  • sequences
  • The processing of POMC involves glycosylations, acetylations, and extensive proteolytic cleavage at sites shown to contain regions of basic protein sequences. (wikipedia.org)
  • dark
  • On an agouti background, Vps33a bf homozygotes have dark ears, opaque eyes, and the belly is lighter in color than is the rest of the coat. (jax.org)
  • background
  • WSB is characterized by a distinct and consistent white head blaze, variable ventral spotting and a slight coat dilution on the agouti background. (jax.org)
  • animal
  • The reliability of the information transmitted by those coloured traits acting as signals in animal communication has frequently been associated with the costs of producing or acquiring pigments. (royalsocietypublishing.org)
  • pattern
  • The pattern is used both in startle or deimatic displays and as a signal to warn off experienced predators. (wikipedia.org)