Adhesion. Medical search. Frequent questions

Patients with leukocyte adhesion deficiency II can generally be treated as outpatients. (medscape.com)
Patients with leukocyte adhesion deficiency II manifest the Bombay phenotype (ie, negative for O and H blood group antigens with potential production of anti-H antibody). (medscape.com)
However, IgM and IgG serum levels are within the reference range in patients with leukocyte adhesion deficiency II. (medscape.com)

The engineering principle behind chemical adhesion in this sense is fairly straightforward: if surface molecules can bond, then the surfaces will be bonded together by a network of these bonds. (wikipedia.org)
In dispersive adhesion, also known as physisorption, two materials are held together by van der Waals forces: the attraction between two molecules, each of which has a region of slight positive and negative charge. (wikipedia.org)
Recent progress has resulted in identification and cloning of adhesion molecules and cytokines, which are important in cellular interactions and cell activation, respectively, and in identification of several cell types that produce cytokines. (nih.gov)
However, the precise relationships between adhesion molecules, cytokines and inflammation have not yet been elucidated. (nih.gov)
Cytokines may selectively induce expression of adhesion molecules. (nih.gov)
There are many other adhesion molecules and counterreceptors on endothelium and leukocytes, and many cytokines other than IL-4 that may influence expression of these molecules. (nih.gov)
Research Objectives and Scope The NIAID and the NHLBI are interested in sponsoring research projects to further understanding of the role of adhesion molecules and cytokines in inflammation, especially allergic inflammation. (nih.gov)
Areas of interest include, but are not limited to, the following: o Cloning the genes that encode adhesion molecules and identifying how these genes are regulated in various microenvironments and at various stages of inflammation. (nih.gov)
The discovery of the carcinoembryonic antigen (CEA) as a tumor marker for colorectal cancer some 50 years ago became the first step in the identification of a much larger family of 12 carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) with surprisingly diverse functions in cell adhesion, in intracellular and intercellular signaling, and during complex biological processes such as cancer progression, inflammation, angiogenesis, and metastasis. (nih.gov)
These fascinating proteins illustrate how a better understanding of the CEACAM family of cell adhesion molecules reveals their functional link to the underlying disease and lead to new monitoring and targeting opportunities. (nih.gov)
A multi-analyte quality control with target values and ranges supplied for 5 different adhesion molecules. (randox.com)
Increased worldwide prevalence of allergic eye pathologies has stimulated the identification of novel drug targets, including eosinophils and adhesion molecules. (frontiersin.org)
Accumulation of eosinophils in the eye is a key event in the onset and maintenance of allergic inflammation and is mediated by different adhesion molecules. (frontiersin.org)
This article reviews recent understanding of the role of adhesion molecules in eosinophil recruitment in the inflamed conjunctiva along with effective treatments for allergic conjunctivitis. (frontiersin.org)
In the following sections, we review eosinophil adhesion molecules and the mechanisms involved in the recruitment of eosinophils to the allergic conjunctiva. (frontiersin.org)
Mast cell degranulation also induces activation of vascular endothelial cells and expression of chemokines and adhesion molecules ( Ono and Abelson, 2005 ). (frontiersin.org)
Along each step of this process different cell adhesion molecules and their ligands mediate recognition between leukocytes and endothelial cells. (frontiersin.org)
Cadherin superfamily of adhesion molecules in primary lung cancer. (nih.gov)
Cadherins are Ca(2+-)dependent cell-cell adhesion molecules which interact with intracellular proteins called catenins. (nih.gov)
Cadherins are the most interesting adhesion molecules and among them most important is epithelial E-cadherin. (nih.gov)
Neutrophils are unable to aggregate and do not bind to intercellular adhesion molecules on endhothelial cells. (lu.se)

Cagdas D, Yilmaz M, Kandemir N, Tezcan I, Etzioni A, Sanal O. A Novel Mutation in Leukocyte Adhesion Deficiency Type II/CDGIIc. (medscape.com)

If my doctor states that is took 45 min or more to do lysis of adhesions, then I bill for the main procedure with a 22 modifier and increase my fee. (aapc.com)
If you check CCI edits it does not allow you to bill for lysis of adhesions, even with a modifier, when performing many surgeries. (aapc.com)
I have a patient that had a Synovectomy& Debridement and a Lysis of Adhesions& Manipulation under Anestheia for a Shoulder surgery. (aapc.com)
Epidural lysis of adhesions is designed to release the tension on the nerves by reducing inflammation and dissipating scar tissues surrounding the nerves. (singhealth.com.sg)
Epidural Lysis of Adhesions - How to prevent? (singhealth.com.sg)

Subsequently, a subset of NCAM translocates from fibroblast growth factor receptor (FGFR) complexes outside lipid rafts into lipid rafts where it stimulates the non-receptor tyrosine kinase p59(Fyn) leading to the phosphorylation and activation of focal adhesion kinase and the assembly of integrin-mediated focal adhesions. (nki.nl)
Through the systematic application of various advanced light microscopy techniques, including super-resolution microscopy, we have described in greater detail the dynamic structure of focal adhesions, protein complexes through which cells attach to a surface. (eur.nl)
We show that the dynamics of focal adhesion proteins correlate with the position and orientation of a focal adhesion within the cell, that focal adhesions around the actin fibre attachment site have a higher density than other areas of the focal adhesion and that the ends of focal adhesions have a unique protein structure. (eur.nl)

Most commonly known as "scar tissue," adhesions are simply scar tissue that forms inside the body. (clearpassage.com)

Hysterosalpingography may help detect adhesions inside the uterus or fallopian tubes. (medlineplus.gov)
No tests are available to detect adhesions. (medlineplus.gov)

This condition, called labial adhesions (sticking together of labia), may occur in the early months of life. (healthychildren.org)
Usually labial adhesions do not cause symptoms, but sometimes they can lead to difficulty with urination and increase a child's risk of urinary tract infections . (healthychildren.org)
Good hygiene, such as giving your child daily sitz baths, is also important in the treatment and prevention of labial adhesions. (healthychildren.org)

Intraperitoneal microbial contamination drives post-surgical peritoneal adhesions by mesothelial EGFR-signaling. (nih.gov)
Di Zerega, G.S., Roth, R. and Johns, D.B. (2003) Quantitation of Peritoneal Adhesions and Correlation with Clinical Outcomes. (scirp.org)

Adhesions occur frequently after abdominal surgery and are the most common cause of bowel obstruction, chronic abdominal pain, and infertility. (medscape.com)
To reduce the formation of adhesions, a mechanical barrier composed of hyaluronic acid and carboxymethylcellulose was developed, to prevent adherence of tissues after abdominal surgery. (medscape.com)
Abdominal adhesions are common and often develop after abdominal surgery. (nih.gov)
People who have had abdominal surgery are more likely to have abdominal adhesions. (nih.gov)
To add insult to injury (on the adhesions front) in June I had abdominal surgery to repair my incisional hernia from my 2007 surgeries, and the pains have been worse. (cancer.org)
Q: I have adhesions as a result of a serious abdominal surgery several years ago. (clearpassage.com)

Adhesions in the pelvis may cause long-term (chronic) pelvic pain. (medlineplus.gov)
Pelvic adhesions that involve scarring of the fallopian tubes can lead to infertility and reproductive problems. (medlineplus.gov)
Abdominal and pelvic adhesions can cause chronic pain. (medlineplus.gov)
What are Pelvic Adhesions? (clearpassage.com)
Some women will never even know that they have pelvic adhesions. (clearpassage.com)
For others, pelvic adhesions lead to a variety of women's health conditions, including chronic pelvic pain and infertility. (clearpassage.com)

[ 1-8 ] Although the majority of patients with intraabdominal adhesions experience no or very little symptoms, abdominal adhesions are a well-known cause of small-bowel obstruction, chronic abdominal pain, and infertility. (medscape.com)
Abdominal adhesions can cause intestinal obstruction and female infertility . (nih.gov)
Adhesions can sometimes cause infertility in women by preventing fertilized eggs from reaching the uterus. (medlineplus.gov)
The Wurns spoke with Dr. Ruscio about abdominal adhesions and how they are a commonly overlooked cause of SIBO (small intestinal bacterial overgrowth), IBS, chronic pain and infertility. (clearpassage.com)
If you are experiencing chronic pain, infertility, or small bowel obstruction, you may have adhesions. (clearpassage.com)
Adhesions can also cause infertility. (earthclinic.com)

The objective of the study was to determine the long-term effect of the use of a hyaluronic acid-carboxymethylcellulose membrane (Seprafilm) on the incidence of adhesions and subsequent small-bowel obstruction and chronic abdominal complaints after colorectal surgery (Hartmann's procedure). (medscape.com)
In the intestines, adhesions can cause partial or complete bowel obstruction . (medlineplus.gov)
Adhesions can cause pain, discomfort and even bowel obstruction. (earthclinic.com)

Antihistamines with multiple mechanisms of action can be effective during the early and late phases of allergic conjunctivitis by blocking the interaction between β 1 integrins and vascular cell adhesion molecule (VCAM)-1. (frontiersin.org)
Loss of expression of the cell-cell adhesion molecule E-cadherin is a hallmark of epithelial-mesenchymal transition (EMT) in development and in the progression from epithelial tumours to invasive and metastatic cancers. (nki.nl)
Here, we demonstrate that the loss of E-cadherin function upregulates expression of the neuronal cell adhesion molecule (NCAM). (nki.nl)
Activated leukocyte cell adhesion molecule: a novel biomarker for breast cancer. (nih.gov)
Activated leukocyte cell adhesion molecule (ALCAM) has been implicated in tumorigenesis. (nih.gov)

nearly every surgical intervention in the abdomen incites the formation of adhesions. (medscape.com)
Adhesions in the belly (abdomen) may cause a blockage of the intestines . (medlineplus.gov)
X-rays of the abdomen, barium contrast studies, and CT scans may help detect a blockage of the intestines caused by adhesions. (medlineplus.gov)
Abdominal adhesions are bands of scar-like tissue that form inside your abdomen . (nih.gov)
Abdominal adhesions can kink, twist, pull, or compress the intestines and other organs in the abdomen, causing symptoms and complications , such as intestinal obstruction or blockage. (nih.gov)
Abdominal adhesions develop in more than 9 out of every 10 people who have surgery that opens the abdomen. (nih.gov)
Almost everyone who has surgery on the abdomen gets adhesions. (medlineplus.gov)

The risk of forming adhesions is high after bowel or female organ surgeries. (medlineplus.gov)
However, the risk for more adhesions goes up with more surgeries. (medlineplus.gov)
My first surgeries were over 3 years ago, and I continued to have pain from adhesions. (cancer.org)
Considering the twofold effect in hemostasis and adhesion prevention, 4DryField ® PH is a very helpful tool especially in extensive and complicated surgeries. (scirp.org)
A problem for some after one or more surgeries are abdominal adhesions. (earthclinic.com)
If you have had multiple surgeries and many adhesions, you may need a large cloth to cover a large area. (earthclinic.com)

Menzies, D. and Ellis, H. (1990) Intestinal Obstruction from Adhesions-How Big Is the Problem? (scirp.org)

This Program Announcement (PA), Cytokines and Adhesion in Allergy and Inflammation, is related to the priority area of diabetes and chronic disabling diseases. (nih.gov)

The results of these methods can be used to assess the likely performance of the sealant bead and to compare the adhesion of different substrate preparations and sealant materials. (astm.org)
When adhering in dry conditions adhesion is surface-insensitive 1 but when water is present the substrate wettability is relevant. (nature.com)
ISO 4624:2016 specifies three methods (i.e. one dolly or two dollies on a painted panel and two dollies, one as painted substrate) for determining the adhesion by carrying out a pull-off test on a single coating or a multi-coat system of paint, varnish or related product. (saiglobal.com)
Advantis solutions improve adhesion in three ways - as a primer between the substrate and subsequent coating, as a primer or tie coat between coating layers and as a stir-in formulation additive," said Doug Wagner, technology director in Eastman's coatings business. (eastman.com)
A coupling agent for the mechanical improvement of a synthetic composite can, for example, in some cases as well be used as an adhesion promoter between a coating and the substrate. (byk.com)
We designed an adhesion test to measure the pull-off force required to detach a pupa from a substrate and to evaluate the contact area covered by the glue. (biorxiv.org)

Tumor necrosis factor-α-primed mesenchymal stem cell-derived exosomes promote M2 macrophage polarization via Galectin-1 and modify intrauterine adhesion on a novel murine model. (nih.gov)
Clinical features of the predilection and severer sites of intrauterine adhesions. (nih.gov)
Clinical study on 2 types of intrauterine stents with different thickness and hardness in the treatment of moderate-to-severe intrauterine adhesions. (nih.gov)

These test methods have been found useful in comparing the adhesion behaviour of different coatings. (saiglobal.com)
Eastman is introducing the next generation of adhesion promoters to keep paint and coatings users compliant with regulatory changes. (eastman.com)
Eastman's Advantis adhesion promoters offer a simple alternative to help our customers remain compliant without the need for reformulation," said Tom Klug, segment market manager for Eastman's automotive coatings business. (eastman.com)
Our Advantis adhesion promoters are a solution that enables customers to avoid relabeling concerns of their current coatings products. (eastman.com)
Irrespective of the definition, these additives can positively influence the adhesion of coatings on aged paintwork, the tolerance towards of surface impurities, and the resistance to moisture and corrosion. (byk.com)
The Elcometer 506 are lightweight, portable, and easy-to-use adhesion testers available in analog or digital gauges and are suitable for measuring the pull-off adhesion of coatings up to 50MPa (7250psi) either on-site or in the laboratory. (aimil.com)
Testing coatings adhesion on concrete & low bond strength substrates such as concrete, wood, or other fibrous materials, a larger surface area of the dolly is required to improve accuracy, repeatability, and reproducibility. (aimil.com)

Advantis™ adhesion promoters limit or remove materials of concern, allowing formulators and end users to deliver dependable results while improving product sustainability and meeting regulatory requirements. (eastman.com)
Leveraging decades of proven science, Advantis was developed as an effortless, drop-in alternative to formulations that use traditional Eastman adhesion promoters. (eastman.com)
Advantis adhesion promoters are commercially available as solutions, water-based dispersions and solid resins. (eastman.com)
The objective of adhesion promoters and coupling agents is to create as many stable additional bonds on these phases. (byk.com)
We hear the terms adhesion promoters, couplers, coupling agents or modifiers, and it seems like the same additive could be used for different applications. (byk.com)

Adhesion is the tendency of dissimilar particles or surfaces to cling to one another (cohesion refers to the tendency of similar or identical particles/surfaces to cling to one another). (wikipedia.org)
Five mechanisms of adhesion have been proposed to explain why one material sticks to another: Adhesive materials fill the voids or pores of the surfaces and hold surfaces together by interlocking. (wikipedia.org)
Chemical adhesion occurs when the surface atoms of two separate surfaces form ionic, covalent, or hydrogen bonds. (wikipedia.org)
Adhesions are bands of scar-like tissue that form between two surfaces inside the body and cause them to stick together. (medlineplus.gov)
However, abdominal adhesions may cause these surfaces to become adherent, or stick together. (nih.gov)
Highlighting the significant contributions that surfaces, adhesive chemistry, polymer behavior, and mechanics make to measured adhesion, the course provides strategic insights for bonding success ranging from structural to soft matter adhesion. (adhesionsociety.org)

These 2 members mediate leukocyte adhesions to endothelial cells but they also serve as receptors for iC3b (inactivated C3b). (medscape.com)

In leukocyte adhesion deficiency type 1, bacterial and fungal infections most commonly occur on the skin and mucous membranes such as the moist lining of the nose and mouth. (nih.gov)
Leukocyte adhesion deficiency type 1 is estimated to occur in 1 per million people worldwide. (nih.gov)

Adhesion Infographic Many people are unaware that they have adhesions - internal scar tissue that forms as part of the body's healing process. (clearpassage.com)
Used faithfully over time they can reduce scar tissue and adhesions. (earthclinic.com)
Abdominal adhesions are a type of scar tissue that causes your internal organs to "stick" together instead of move freely as they are intended to. (earthclinic.com)

1,2,3 However, a majority of people with abdominal adhesions do not develop symptoms or complications. (nih.gov)
If you have symptoms such as low back pain or pain shooting into your arms or legs, you may have nerve irritation secondary to epidural adhesions. (singhealth.com.sg)
Symptoms of leukocyte adhesion deficiency usually begin during infancy and include frequent infections in soft tissues, such as the gums, skin, and muscles. (msdmanuals.com)
Symptoms of leukocyte adhesion deficiency usually begin during infancy. (msdmanuals.com)

Here, we showed that membrane-targeted chloride intracellular channel 1 (CLIC1) spatiotemporally regulates the formation of cell-matrix adhesions and membrane protrusions through the recruitment of PIP5Ks to the plasma membrane. (jci.org)

Note 3: In surgery, adhesion is used when two tissues fuse unexpectedly. (wikipedia.org)
Adhesions can cause various disorders, depending on the tissues affected. (medlineplus.gov)
Adhesions cause tissues and organs to stick together. (medlineplus.gov)

Starting from birth, people with leukocyte adhesion deficiency type 1 develop serious bacterial and fungal infections. (nih.gov)
Thus, patients with this type of leukocyte adhesion deficiency manifest both severe bacterial infections and bleeding disorder. (medscape.com)
Dogs with canine leukocyte adhesion deficiency or CLAD, similar to children with LAD-1, suffer from recurrent bacterial infections and early death due to the absence of the CD18 integrin on leukocytes. (nih.gov)

Large size peritoneal trauma from extended surgery for high-grade expansive uterus pathology or endometriosis might result in severe diffuse bleeding and peritoneal adhesion formation with objectionable sequelae. (scirp.org)

Membrane protrusion and adhesion to the extracellular matrix, which involves the extension of actin filaments and formation of adhesion complexes, are the fundamental processes for cell migration, tumor invasion, and metastasis. (jci.org)

Changes in cell adhesion contribute to the initial migration and invasion of malignant tumor cells, the first steps leading to metastasis. (avivasysbio.com)
In later steps of metastasis, cell adhesion is vital for the entry of cancer cells into the blood, their survival, and their establishment at distant sites in the body. (avivasysbio.com)
This study reveals what we believe is an unrecognized mechanism that spatiotemporally coordinates the formation of both lamellipodium/invadopodia and nascent cell-matrix adhesions for directional migration and tumor invasion/metastasis. (jci.org)

2014) Consensus Recommendations on Adhesions (Version 2014) for the ESGE Adhesions Research Working Group (European Society for Gynecological Endoscopy): An Expert Opinion. (scirp.org)

This talk presents the anti-adhesion behaviors of solid hydrate particle at the water-oil interface under various surface-active agents. (aiche.org)

My guess is that it was poor adhesion to the oak strip - could be an issue of temperature of the hotmelt, condition of the band (dull blade will cause glazing on the wood that won't accept hotmelt well), or incorrectly adjusted pressure station. (woodweb.com)
4.7 The results of these methods are most useful in identifying sealant beads with poor adhesion. (astm.org)

As expected, under wet conditions, adhesion on a hydrophilic surface (glass) was lower than that on a hydrophobic surface (alkyl-silane monolayer on glass). (nature.com)
They can prevent adhesion of aqueous phase to the hydrophilic surface of the probe, and this anti-adhesive effect is not changed by an addition of sodium dodecyl sulfate (SDS). (aiche.org)

Two mutations in the KINDLIN3 gene of a new leukocyte adhesion deficiency III patient reveal distinct effects on leukocyte function in vitro. (medscape.com)
Gene therapy for leukocyte adhesion deficiency. (medscape.com)
Mutations in the ITGB2 gene cause leukocyte adhesion deficiency type 1. (nih.gov)
ITGB2 gene mutations that cause leukocyte adhesion deficiency type 1 lead to the production of a β2 subunit that cannot bind with other subunits to form β2 integrins. (nih.gov)
Cell adhesion plays important roles in the normal functions of cells, contributing to cellular organization and structure, proliferation and survival, and gene expression. (avivasysbio.com)
This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. (nih.gov)

There is no single theory covering adhesion, and particular mechanisms are specific to particular material scenarios. (wikipedia.org)
We implement novel imaging methods and quantitative models to document the embryonic development of the C. elegans brain neuropil , and discover that differential adhesion mechanisms control precise placement of single neurites onto specific layers. (elifesciences.org)

We Decrease or Eliminate Adhesions Without Surgery Overview Adhesions, the internal scars that tend to form whenever the body heals, are a major problem for patients and their physicians. (clearpassage.com)
While these internal scars initially formed to help the body heal from tissue damage, adhesions tend to remain long after the initial tissue damage has passed. (clearpassage.com)
Scars or adhesions may form in the epidural space after an injury or back surgery. (singhealth.com.sg)

A novel genetic leukocyte adhesion deficiency in subsecond triggering of integrin avidity by endothelial chemokines results in impaired leukocyte arrest on vascular endothelium under shear flow. (medscape.com)
CD11a/CD18 (LFA-1) expressed on lymphocytes is known to play an important role in lymphocyte trafficking (adhesion to vascular endothelium), as well as interactions to antigen presenting cells (APC). (medscape.com)

Abdominal adhesions are the most common cause of obstruction of the small intestine . (nih.gov)

Preimplantation genetic diagnosis of leukocyte adhesion deficiency type I. Fertil Steril . (medscape.com)
Retinal researchers at the Institute for Genetic Medicine at Newcastle University (UK) and New Cells Biotech have achieved this by using low-adhesion cell culture conditions. (onenucleus.com)

The adhesion strength of the test core is determined by converting the maximum hydraulic pressure value, saved on the pressure gauge's digital display, to the maximum tensile stress acting normal to the core's failure surface. (cdc.gov)
Typical adhesion test results comparing tensile strength with shotcrete curing age are shown in Figure 4. (cdc.gov)
Both of these types of systems can be used to undertake a variety of other dentistry tests involving compression, tensile adhesion, and flexural tests. (instron.com)

Furthermore, we assessed the contribution of VWF to platelet adhesion, by measuring the ability of plasma from patients with cirrhosis to support adhesion of normal or patient platelets under flow conditions. (nih.gov)
Another reported type of leukocyte adhesion deficiency involves dysfunction in platelet aggregation in addition to a defect in leukocyte adhesion. (medscape.com)

What are the complications of abdominal adhesions? (nih.gov)

Also, special blood tests, including analysis of proteins on the surface of white blood cells (called flow cytometry), are used to diagnose leukocyte adhesion deficiency. (msdmanuals.com)

Hematopoetic Stem Cell Transplantation in Neutrophil Disorders: Severe Congenital Neutropenia, Leukocyte Adhesion Deficiency and Chronic Granulomatous Disease. (medscape.com)
Leukocyte Adhesion Deficiency Type III: Clinical Features and Treatment With Stem Cell Transplantation. (medscape.com)
Nonmyeloablative hematopoietic stem cell transplantation corrects the disease phenotype in the canine model of leukocyte adhesion deficiency. (medscape.com)
Cell adhesion-based therapeutic strategies and the use of dissociated glucocorticoid in allergic conjunctivitis are also conceptualized. (frontiersin.org)
We have investigated the mechanism and activity of the human neuraminidase (NEU) isoenzyme, NEU3, on T cell adhesion receptors. (frontiersin.org)
Later steps of the process must arrest the cell (firm adhesion) to allow for transmigration. (frontiersin.org)
The prominent role of sialic acid in adhesion suggests that changes which affect sialoglycoconjugates (SGC) may be critical to regulation of cell-cell interactions. (frontiersin.org)
This session will focus on experimental and theoretical aspects of prokaryotic and eukaryotic cell adhesion/migration. (confex.com)
Papers may also include studies of matrix remodeling (proteolysis, contraction, synthesis), matrix-driven phenotype, or tissue architecture regulation of cellular processes, as well as evaluation of critical biomaterial design parameters for controlling cell adhesion and migration. (confex.com)
Studies have shown that Lipidure® coated plates promote the formation of a single spheroid in concave (U or V-shaped) wells, while other brands of plate lead to formation of satellite spheroids - indicating a higher degree of cell adhesion is taking place. (onenucleus.com)
For further information on the use of Lipidure® coated low adhesion plates for organoid cell culture please visit www.amsbio.com/Lipidure-Coat.aspx or contact AMSBIO now on +44-1235-828200 / +1-617-945-5033 / [email protected] . (onenucleus.com)
This contribution demonstrates a simple and reproducible method for fabricating surface-tethered polymer brushes that vary in grafting density for peptide adsorption and cell-adhesion studies. (aiche.org)
Variants of leukocyte adhesion deficiency have also been reported, including fully expressed but nonfunctional CD18 and an E selectin that is expressed but rapidly cleaved from the cell surface (only present in soluble form). (medscape.com)
During development, cell adhesion is important for the correct movements of cells modeling the embryo. (avivasysbio.com)
In the adult, appropriate cell adhesion is necessary for numerous physiological processes and can be deranged in many diseases, including cancer. (avivasysbio.com)
In response to migration-related stimuli, CLIC1 recruited PIP5K1A and PIP5K1C from the cytoplasm to the leading edge of the plasma membrane, where PIP5Ks generate a phosphatidylinositol 4,5-bisphosphate-rich (PIP2-rich) microdomain to induce the formation of integrin-mediated cell-matrix adhesions and the signaling for cytoskeleon extension. (jci.org)
Ablation of NCAM expression during EMT inhibits focal adhesion assembly, cell spreading and EMT. (nki.nl)
These results establish a mechanistic link between the loss of E-cadherin expression, NCAM function, focal adhesion assembly and cell migration and invasion. (nki.nl)

Bunting M, Harris ES, McIntyre TM, Prescott SM, Zimmerman GA. Leukocyte adhesion deficiency syndromes: adhesion and tethering defects involving beta 2 integrins and selectin ligands. (medscape.com)
Leukocyte adhesion deficiency type I (LAD I) is a failure to express CD18, which composes the common ß 2 subunit of LFA1 family (ß2 integrins). (medscape.com)

Depending on the location of the adhesions, a barrier may be placed at the time of surgery to help reduce the chance of the adhesions returning. (medlineplus.gov)
2) transformed into gel, 4DryField ® PH forms an adhesion prevention barrier. (scirp.org)
Dripped with saline solution, 4DryField ® PH immediately formed a viscous gel acting as a barrier for adhesion prevention. (scirp.org)
Safeguard the barrier properties in the laminate structure through the BOBST AluBond high metal adhesion process to provide the required shelf life for your packaging. (canadianpackaging.com)

Leukocyte adhesion deficiency (LAD) is a rare primary immunodeficiency. (medscape.com)
Leukocyte adhesion deficiency is an immunodeficiency disorder in which white blood cells (leukocytes) do not function normally, causing frequent soft-tissue infections. (msdmanuals.com)

Sealant formulations may fail in cohesion or adhesion when properly installed, and evaluated by this method. (astm.org)
Note 2 - Sealant formulations may fail in cohesion or adhesion when properly installed, and tested by this method. (astm.org)

Adhesions in joints, tendons, or ligaments make it harder to move the joint. (medlineplus.gov)
Adhesion in elastic joints is well understood, with models like the JKR (Johnson-Kendall-Roberts), DMT (Derjaguin-Muller-Toporov), and Maugis-Dugdale exhibiting excellent agreement with experiments. (materialstoday.com)

After initial diagnosis and stabilization, patients with leukocyte adhesion deficiency I can usually complete parenteral antibiotics in the home setting. (medscape.com)
Cox DP, Weathers DR. Leukocyte adhesion deficiency type 1: an important consideration in the clinical differential diagnosis of prepubertal periodontitis. (nih.gov)

This work highlights the need to utilize morphology and surface chemistry in developing successful synthetic adhesives with desirable adhesion and self-cleaning properties. (nature.com)

Etzioni A. Leukocyte adhesion deficiencies: molecular basis, clinical findings, and therapeutic options. (medscape.com)

Currently, 18 subtypes have been reported: 12 are type I (dysfunctional lipid-linked oligosaccharide precursor synthesis), and 6 are type II (dysfunctional trimming/processing of the protein-bound oligosaccharide), including leukocyte adhesion deficiency II (CDG-IIc). (medscape.com)
This protein plays a role in signal transduction by interacting with fibroblast growth factor receptors, N-cadherin and other components of the extracellular matrix and by triggering signalling cascades involving FYN-focal adhesion kinase (FAK), mitogen-activated protein kinase (MAPK), and phosphatidylinositol 3-kinase (PI3K). (nih.gov)

Seprafilm is a bioresorbable membrane developed to prevent the formation of adhesions. (medscape.com)
A hallmark of leukocyte adhesion deficiency type 1 is the lack of pus formation at the sites of infection. (nih.gov)
With images compiled from a presentation at a conference of physicians, the video provides an in-depth overview of the biomechanics of adhesion formation and the ways in which manual physical therapy can be an effective treatment. (clearpassage.com)

LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rap1 activation and impaired stabilization of integrin bonds. (medscape.com)
This leukocyte adhesion deficiency variant is associated with defective expression of the Rap-1 activator CalDAG-GEFI. (medscape.com)

In particular, they investigated the adhesion behaviour between polydimethylsiloxane (PDMS) and a glass colloidal probe, using a fracture mechanics approach. (materialstoday.com)
When force curves were acquired at low speeds, they found that adhesion behaviour was consistent across all the samples. (materialstoday.com)

Anatomy41

Organisms6

Diseases7

Chemicals and Drugs125

Analytical, Diagnostic and Therapeutic Techniques and Equipment23

Phenomena and Processes50

Disciplines and Occupations2

Technology, Industry, Agriculture6

Information Science4

Patients with leukocyte adhesion defi3

Molecules21

Leukocyte Adhesion Deficienc1

Lysis of Adhesions5

Focal adhesions3

Tissue Adhesions1

Detect adhesions2

Labial Adhesions3

Peritoneal adhesions2

Abdominal surgery6

Pelvic6

Infertility6

Bowel obstruction3

Molecule5

Abdomen7

Surgeries6

Intestinal obstruction1

Cytokines1

Substrate6

Intrauterine3

Coatings7

Promoters5

Surfaces6

Endothelial cells1

Occur2

Scar tissue3

Symptoms4

Intracellular1

Tissues3

Bacterial3

Uterus1

Actin1

Metastasis3

Endoscopy1

Anti-adhesion1

Poor adhesion2

Hydrophilic surface2

Gene6

Mechanisms2

Scars3

Vascular2

Obstruction1

Genetic2

Tensile3

Platelet2

Complications1

Proteins1

Cell18

Integrins2

Barrier4

Immunodeficiency2

Cohesion2

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Diagnosis2

Desirable1

Therapeutic1

Protein2

Formation3

Associated with defective2

Behaviour2