Abstract pathological improves cardiovascular cardiovascular physiological phenomena. Medical search. Frequent questions

Their concentration increases specifically and differently during various pathological states, including cardiovascular diseases ( table 1 ) [ 8 ]. (ersjournals.com)
However, the great challenge today is to delay the onset and severity of non-AIDS-defining comorbidities, which appear much earlier in HIV-infected individuals [ 5 ] and include cardiovascular diseases, diabetes mellitus , kidney, liver, and bone alterations, and neoplasia [ 4 - 8 ]. (hindawi.com)
Senescent cells affect tumour suppression, wound healing and possibly embryonic/placental development and a pathological role in age-related diseases. (wikipedia.org)
scholarship on "Effects of snoring and obstructive sleep apneas on attention and supervision and on the cardiovascular system" delivered by the Consortium for the management of the clinic for nervous and mental diseases, University of Bologna. (unibo.it)
Pathogenetic mechanisms and medical behaviours which can improve health in patients with dementia, Parkinson disease and motoneuron diseases" scientific coordinator: C. Caltagirone. (unibo.it)
Mitochondrial dysfunction has been proven to play a critical role in the pathogenesis of cardiovascular diseases. (frontiersin.org)
We hope this review will provide perspectives on mitochondrial-targeted therapeutics in cardiovascular diseases. (frontiersin.org)
The abnormal morphology and dysfunction of mitochondria have been proven as the principal mechanisms in the pathogenesis of cardiovascular diseases, such as heart failure, myocardial infarction, atherosclerosis, and hypertension ( 4 - 6 ). (frontiersin.org)
So mitochondria-targeted therapy is suggested to be a potential treatment strategy for cardiovascular diseases. (frontiersin.org)
However, clinical trials of these agents for cardiovascular diseases were hardly approved to carry out, even less to evaluate their clinical effectiveness and safety. (frontiersin.org)
Therefore, patients with cardiovascular diseases would fail to achieve the desired outcomes by using these mitochondrial-targeted drugs ( 5 ). (frontiersin.org)
Cardiovascular diseases are one of the leading causes of death globally and the most common pathological process is atherosclerosis. (openbiomedicalengineeringjournal.com)
Cardiovascular Diseases (CVDs) are the most common reason for death and they are considered to be one of the most important problems related to human health worldwide. (openbiomedicalengineeringjournal.com)
Immune dysregulation has been identified as a critical cause of the most common types of cardiovascular diseases (CVDs). (biomedcentral.com)
Many types of cardiovascular diseases (CVDs) are associated with complex immune responses that can significantly contribute to their progression and remission. (biomedcentral.com)
MS has been proven to be associated with an increased incidence of cardiovascular diseases and type 2 diabetes mellitus, leading to morbidity and mortality. (biomedcentral.com)
Manipulation of the gut microbiota through the administration of prebiotics or probiotics may assist in weight loss and reduce plasma glucose and serum lipid levels, decreasing the incidence of cardiovascular diseases and type 2 diabetes mellitus. (biomedcentral.com)
MS is closely related to lifestyle and central obesity, serving as a risk factor for metabolic diseases, such as type 2 diabetes and cardiovascular disease. (biomedcentral.com)
This review describes, analyzes and compares the effects of different types of diets in reducing the onset of typical Western countries non-communicable diseases (NCDs) (cardiovascular diseases, tumors, chronic respiratory diseases, diabetes, etc.), thus increasing the average lifespan. (iospress.com)
Cardiovascular diseases (CVDs) account for most NCDs deaths (17.7 million people annually), followed by cancers (8.8 million), respiratory diseases (3.9 million) and diabetes (1.6 million) [ 1 ]. (iospress.com)
It is very popular for its preventive use in several diseases: It seems to reduce the risk of the onset or decrease some phenomena related to inflammation, oxidative stress, and conditions of dysregulation of the immune response. (edu.mx)
Endotoxemia and systemic inflammation caused by intestinal mucosal barrier defects are risk factors for cardiovascular diseases. (xiahepublishing.com)
It can be enforced to identify phenomena related to the ANS in healthy subjects and patients with certain diseases, such as diabetes mellitus 8, 9 , chronic obstructive pulmonary disorder (COPD) 10 , epilepsy 11,12 and those referred to as "dynamical diseases 13 . (bvsalud.org)
The US Centers for Disease Control and Prevention (CDC), the Lancet Commission on Hypertension Group, Resolve to Save Lives (RTSL), and the World Hypertension League (WHL) share a collective goal of expanding the evidence base on hypertension, sodium, and trans fatty acid reduction strategies as a critical pathway to preventing and managing cardiovascular diseases. (cdc.gov)

Advanced glycation end products (AGEs) are a consequence of oxidative stress which occur during normal physiological conditions such as aging. (hindawi.com)
Different findings (in vitro, in vivo, and clinical ones), summarized and analyzed in this review, have showed an important role of ALA in other various non-COVID physiological and pathological situations against "cytokines storm," chemokines secretion, oxidative stress, and dysregulation of immune cells that are also involved in the infection of the 2019 novel coronavirus. (edu.mx)

Patients with PH exhibited higher circulating levels of microparticles compared to control subjects and in vitro or in vivo generated microparticles can induce endothelial dysfunction, interfere with coagulation pathways or modulate inflammatory phenomenon. (ersjournals.com)
So far CVR-L-Arg has been used to study cerebral endothelial function in many pathological conditions such as stroke, migraine, etc. (hindawi.com)
In conclusion CVR-L-Arg is a promising noninvasive research method that could provide means for evaluation of cerebral endothelial function in physiological and pathological conditions. (hindawi.com)
Endothelial cells are highly metabolically active and play an important role in many physiological functions, including the control of vasomotor tone, blood cell trafficking, haemostatic balance, permeability, proliferation, and immunity. (hindawi.com)
Endothelial cell phenotypes are differentially regulated in space and time, giving rise to the phenomenon of endothelial cell heterogeneity. (hindawi.com)
Endothelial hyperpermeability induced by hyperglycemia is the initial step in the development of atherosclerosis, one of the most serious cardiovascular complications in diabetes. (springer.com)
Resveratrol also down-regulated the increased expressions of vascular endothelial growth factor (VEGF) and kinase insert domain receptor (KDR, or VEGF receptor-2) induced by high glucose. (springer.com)
In particular, it plays a vital role in the physiological and pathological activities of the three important cells, Endothelial cells, macrophages and vascular smooth muscle cells. (wjgnet.com)
Nowadays, more and more studies have revealed that cells in the cardiovascular system (such as cardiomyocytes, vascular smooth muscle cells, endothelial cells, et al. (frontiersin.org)

ABSTRACT The Arab world is experiencing an epidemic of obesity and type 2 diabetes mellitus. (who.int)

Notably, the innate and adaptive immune responses under physiological conditions are typically regulated with high sensitivity to avoid the exacerbation of inflammation, but any dysregulation can probably be associated with CVDs. (biomedcentral.com)
Many studies have further demonstrated that SARS-CoV-2 (COVID-19) has dramatically increased the risks of CVDs due to inflammation, so PGRN has drawn much more attention among scholars. (biomedcentral.com)
In all types of CVDs, inflammation has been further documented as one of the critical events in the initiation and spread of the pathological processes. (biomedcentral.com)

Distinguishing physiological arterial compression from pathological stenosis is essential. (ecrjournal.com)

Tegaserod, a selective agonist that acts at 5-HT4 receptors and increases small bowel transit, stimulates intestinal secretion and inhibits visceral afferent responses has proven effective in the treatment of chronic constipation in adults. (ac.ir)

Biomed 2 EU project "Clinico-pathological features and pathogenesis of fatal familial insomnia (FFI)" contract n° BMH4-CT96-0856. (unibo.it)

In the United States, the use of NSAIDs increased by 125% from 1999 to 2002. (biomedcentral.com)
John A. Durango, CO) Assignee(s): lining Biomedical, Inc. Denver, CO) Patent Number: 6,643,546 trend increased: February 13, 2002 oxygen: An support and population for rhythm of awake Cell transport from the proper end of the hyalinosis. (augenta.net)

The heart rate variability is a useful method to assess cardiac autonomic modulation in patients undergoing dental procedures, because knowledge of physiological conditions provides greater security to the professional as well as the possibility of a better plan treatment to patient benefit. (biomedcentral.com)
Pathological variants in TRPM4 gene have been linked to several cardiac phenotypes such as complete heart block (CHB), ventricular tachycardia, and Brugada syndrome (BrS). (frontiersin.org)
In conclusion, decreased or increased protein expression of several TRPM4 variants linked to cardiac conduction disorders or ventricular arrhythmias were found to be caused by altered TRPM4 half-life compared to the WT form. (frontiersin.org)
However, the physiological role for this channel in cardiac function remains unclear. (frontiersin.org)
book delphi developers guide: Journal of Cardiac Abstract. (augenta.net)
It is important to clearly delimit the adaptive of the pathological characteristics of the cardiovascular system of athletes, as we unfortunately witnessed frequent instances of sudden cardiac death of athletes, where often unrecognized causes of death are electrophysiological disorders. (studylib.net)

In the last decades, numerical simulations have been widely used to assess the blood flow behavior in stenotic arteries and, consequently, providing insights into the cardiovascular disease condition, its progression and therapeutic optimization. (openbiomedicalengineeringjournal.com)
Recently, the etiology of catamenial pneumothorax has been more accurately diagnosed because of increased awareness and interest in the disease. (intechopen.com)
Inhibition of these latter pathways may be a therapeutic target to prevent the elongation which is associated with increased binding of atherogenic lipids and the disease process of atherosclerosis. (openbiochemistryjournal.com)
In pediatric congenital heart disease (CHD) patients, manipulation of resident progenitor cells may provide important new approaches to improving outcomes. (stanford.edu)
Increased creatinine production and reduced renal clearance in patients with chronic kidney disease (CKD) are likely to lead to accumulation of inflammatory factors in the body. (xiahepublishing.com)
This review summarizes the major pathological factors linking obesity to diabetes, focussing on current epidemiological data related to obese diabetic patients in the Arab world, the etiology of the disease and the genetic determinants of diabetes and obesity. (who.int)

Atherosclerosis, one of the most serious cardiovascular complications of diabetes mellitus, occurs primarily in coronary arteries, lower extremities and extracranial carotid arteries. (springer.com)

The control of the cardiovascular system is accomplished in part by the autonomic nervous system (ANS), which is composed by the sympathetic and parasympathetic pathways that command the cardiovascular system by releasing neurotransmitters that increase or decrease heart rate (HR), respectively. (biomedcentral.com)
Genetic, environmental, behavioral and dietary factors influence the pathways that regulate aging and life expectancy, thus rendering longevity a very complex phenomenon. (iospress.com)

Studies have shown that cell-to-cell mitochondrial transfer plays an essential role in regulating cardiovascular system development and maintaining normal tissue homeostasis under physiological conditions. (frontiersin.org)
In pathological conditions, damaged cells transfer dysfunctional mitochondria toward recipient cells to ask for help and take up exogenous functional mitochondria to alleviate injury. (frontiersin.org)
can act as donors or recipients during mitochondrial transfer under physiological conditions ( 8 - 12 ). (frontiersin.org)
In vivo studies represent more accurately the physiological conditions and provide the most realistic data. (openbiomedicalengineeringjournal.com)
however, a progressive increase of sick people, elderly people in particular, which are affected by multiple chronic conditions [ 8 ], will render this approach less and less sustainable. (iospress.com)

On the other hand, the number of circulating hEPC is increased in hypoxia or acute myocardial infarction (AMI). (intechopen.com)
duration of rate by fire and Abstract for myocardial infection heart and volume. (augenta.net)
9 The theory that a decrease in compliance and an increase in fibrosis is associated with the discovery of a higher incidence of MB, is supported by other studies in which there was a higher incidence of MB in patients with left ventricular hypertrophy (LVH), the hallmark of which is the development of myocardial fibrosis. (ecrjournal.com)

These studies suggest novel mechanisms involved in the development of affective disorders, and highlight the noradrenergic system in the vBNST as a common substrate for the manifestation of pathological anxiety and addiction. (nature.com)

Modern lifestyles and trends that promote overconsumption and unhealthy practices have contributed to an increase in the annual incidence of diabetic AS worldwide, which has created a heavy burden on society. (wjgnet.com)
Metabolic syndrome (MS) comprises central obesity, increased plasma glucose levels, hyperlipidemia and hypertension, and its incidence is increasing due to changes in lifestyle and dietary structure in recent years. (biomedcentral.com)

exhibiting runners to investigate the inmunosuppressant-related book delphi developers guide to opengl 1999 instrument situation: the presenting Cardiovascular Outcomes in Nova Scotia( ICONS) heart. (augenta.net)
anastomosing Cardiovascular Outcomes in Nova Scotia articles. (augenta.net)

Over the years, these cardiovascular complications have been extensively studied by applying in vivo , in vitro and numerical methods ( in silico ). (openbiomedicalengineeringjournal.com)

With the increasing prevalence of diabetes mellitus, diabetic neuropathy has become the primary cause of chronic nephropathy cases. (xiahepublishing.com)

Although the exact role of cellular microparticles remains partially understood, there is increasing evidence to suggest an active role for microparticles in PH pathophysiology. (ersjournals.com)
Endothelium forms the inner cellular lining of blood vessels and plays an important role in many physiological functions including the control of vasomotor tone. (hindawi.com)
In this review, we summarized the mechanism of mitochondrial transfer in the cardiovascular system and outlined the fate and functional role of donor mitochondria. (frontiersin.org)
However, this inflammatory response has a dual function: it can play a protective role by increasing Aβ degradation and clearance, but it can also contribute to Aβ and tau overproduction and induce neurodegeneration and synaptic loss. (biomedcentral.com)
Here, we have reviewed recent studies concerning the role of the gut microbiota in metabolic syndrome and the effects of probiotic bacterial strains and prebiotics on the prevention or treatment of metabolic syndrome, such as their anti-obesity and anti-inflammatory effects and their ability to improve glycemic control and modulate serum lipids. (biomedcentral.com)

5 Prevalence is also increased in patients with hypertrophic cardiomyopathy (HCM) and in heart transplant recipients. (ecrjournal.com)

A high HRV is a sign of good adaptation, featuring a healthy individual, with efficient autonomic mechanisms, whereas low variability is often an indicator of abnormal and insufficient adaptation of the ANS, implying the presence of physiological malfunction in the individual [ 4 ]. (biomedcentral.com)
Methods: We conducted an in-silico sensitivity study on physiological and pathologi- cal mechanisms potentially underlying the clinical HCM phenotype. (kit.edu)
A combination of pathological mechanisms led to reduced and slower deformation of the LV and halved the longitudinal shortening of the LA. Conclusions: This study uses a computer model to determine the changes in LV deformation caused by pathological mechanisms that are presumed to underlay HCM. (kit.edu)

In 2005, undeveloped countries such as Costa Rica spent two million dollars on NSAIDs, which represented an increase of 25% from the expenditure in 2001 [ 6 ]. (biomedcentral.com)

Because Radiofrequency (RF) energy has been shown to renew and restore spatial structural arrangement of collagen fibers, treatment of ED with RF could lead to anatomical and physiological changes at the penile tissue level and could lead to improvement in the erectile mechanism. (researchgate.net)
The physiological importance for cell senescence has been attributed to prevention of carcinogenesis, and more recently, aging, development, and tissue repair. (wikipedia.org)
A fivefold increase in tissue stiffness caused a more homogeneous distribution of the strain values among 17 heart segments. (kit.edu)

We consulted the following databases: Medical Literature Analysis and Retrieval System Online (MEDLINE), Scientific Electronic Library Online (SciELO), Latin American and Caribbean Health Sciences (LILACS) and The Cochrane Library (Cochrane), using terms: "autonomic", "dentistry", "heart rate variability", "cardiovascular physiology" in English and Portuguese. (biomedcentral.com)

Phenomena of "sports heart", in sport medicine and medicine in general represents an important question, because of differentiation of this physiological hypertrophy from pathological, which occurs both in cardiological and noncardiological states. (studylib.net)

They demonstrated that transferring functional mitochondria of bone marrow-derived stem cells to defective parenchymal cells increases the aerobic respiration capacity of recipient mitochondria ( 7 ). (frontiersin.org)

We also discussed the advantage and challenges of mitochondrial transfer strategies, including cell-based mitochondrial transplantation, extracellular vesicle-based mitochondrial transplantation, and naked mitochondrial transplantation, for the treatment of cardiovascular disorders. (frontiersin.org)
Spinal cord injury, arthritis, back disorders, cerebral palsy, neuromuscular disorders, fibromyalgia, and other physiological problems also affect a person's ability to move, something that cannot always be adjusted with prosthetics alone 2 . (uab.edu)

Melatonin as a Medicament for the 24/7 Society: Normal and Pathological Aging -- 14. (nshealth.ca)
Combining the phenomenon of aging and good health is therefore one of the biggest social challenges of today's world. (iospress.com)
Aging is a biological and psychological phenomenon that affects the family and social level. (bvsalud.org)
Aging is a physiological process that involves all living things and is connected to the loss of skills, the way of life in the past, genetics, and emotional and psychological changes. (bvsalud.org)

FOS reduces fecal pH, increases the water, holding capacity of stool and fecal weight and decreases intestinal transit time. (ac.ir)

progression: A high-risk growth pumping from form of Abstract or heart of the important exercise( identification bladder) in the T and need results, and charged by an treatment in contribution invention hormone. (augenta.net)

This is not a physiological model, it just looks at how manipulating delta psi with substrate/inhibitors controls ROS generation. (blogspot.com)

SPORTS HEART SYNDROME Abstract „Sports heart syndrome" represents morphological, functional and electrophysiological changes that appear a consequence of adaptation cardiovascular system onto physical training in maximum load zone. (studylib.net)
Referring to frequent examples of sudden heart death of sportsmen, it is of an extreme value to dissimilitude changes onto the heart that arise as a consequence of adaptation to physical activity, from the changes that are characteristical for different pathological states. (studylib.net)

The decline in functional capacity is a heterogeneous phenomenon in the elderly. (mdpi.com)

The knowledge of physiological responses involved in oral treatment is important for providing an appropriate treatment plan for the patient, and, thus, increased security to the dentist. (biomedcentral.com)
Extremely important thing, both for doctors and trainers is the diference between symptoms and results of sports heart comparing to pathological states that can be life threatening, because there is a crucial difference between prohibition of active sports training and prohibition of sport activities in general. (studylib.net)
An important strategy for achieving this goal is to increase opportunities for investigators in low and middleincome countries to contribute their studies in these areas to the scientific literature. (cdc.gov)

Cellular senescence is a phenomenon characterized by the cessation of cell division. (wikipedia.org)

Peripheral Innervation of Neuroendocrine-Immune System: The Challenges to Change a Physiological Paradigm -- 8. (nshealth.ca)

The phenomenon of intercellular mitochondrial transfer has been discovered in the cardiovascular system. (frontiersin.org)

Upon addition of cycloheximide, WT-TRPM4 decayed with a half-life of ~20 h, while loss-of-expression variants showed a ~30% increase in degradation rate, with a half-life close to 12 h. (frontiersin.org)

1999 ). Report showed that VEGF increased the permeability through caveolae-mediated transcellular pathway in the blood-tumor barrier (Zhao et al. (springer.com)

The sympathetic branch increases HR, promoting reduced RR intervals and decreasing heart rate variability. (biomedcentral.com)

Plus, because it becomes obvious in the later months of the study (from HbA1c values) that insulin is going to have to be added back in, at this time the rate of weight gain might actually increase (dramatically), but we can't know that. (blogspot.com)

Patients with long-standing type 2 diabetes and obesity on IT can, with sufficient weight loss achieved through a low-energy TDR intervention, reduce insulin burden and improve QoL. (blogspot.com)

Overdiagnosis by "consensus-2" criteria has potential to be problematic, but underdiagnosis by "consensus-1" criteria seems the far larger problem given (1) increasing appreciation that MCAS is prevalent (up to 17% of the general population), and (2) most MCAS patients, regardless of illness duration prior to diagnosis, can eventually identify treatment yielding sustained improvement. (degruyter.com)
La présente analyse récapitule les facteurs pathologiques majeurs liant l'obésité au diabète, en se concentrant sur les données épidémiologiques actuelles relatives aux patients diabétiques obèses dans le monde arabe, l'étiologie de la maladie et les déterminants génétiques du diabète et de l'obésité. (who.int)

Anatomy2

Diseases1

Chemicals and Drugs1

Phenomena and Processes33

Information Science2

Health Care1

Diseases24

Oxidative stress2

Endothelial9

Type 2 diabet1

CVDs3

Stenosis1

Secretion1

Pathogenesis1

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Cardiac6

Disease6

Atherosclerosis1

Pathways2

Conditions5

Myocardial3

Manifestation1

Incidence2

Outcomes2

Complications1

Diabetes mellitus1

Role5

Prevalence1

Mechanisms3

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Tissue3

Autonomic1

Occurs1

Mitochondria1

Disorders2

Aging4

Intestinal1

Progression1

Substrate1

Consequence2

Functional1

Important3

Cellular1

Immune1

System1

Degradation1

Pathway1

Heart1

Study1

Insulin1

Patients2