pairs of autosomes

  • Normally, humans have 46 chromosomes, namely 22 pairs of autosomes and 1 pair of sex chromosomes. (medindia.net)
  • Each organism of a species is normally characterized by the same number of chromosomes in its somatic cells, 46 being the number normally present in humans, including 22 pairs of autosomes and the two sex chromosomes (XX or XY), which determine the sex of the organism. (thefreedictionary.com)

female sex

  • For example, a child with female sex organs may not start having periods . (ballysillangrouppractice.co.uk)
  • It is a condition characterized by male-to-female sex reversal in the presence of a normal 46,XY karyotype. (abcam.cn)
  • An ovarian segment can be preserved in people who are given a female sex assignment. (medscape.com)
  • Clitoral recession, vaginoplasty, and labioscrotal reduction are necessary for people with ovotesticular disorder of sexual development who are given a female sex assignment. (medscape.com)

karyotype

  • Androgen insensitivity refers to the inability of the body of an individual with a 46, XY karyotype (usually leading to normal male development) to properly respond to male sex hormones (androgens). (nih.gov)

chromosomes

  • Some people have XY (male) chromosomes, but their external genitals may appear entirely female or atypical. (ballysillangrouppractice.co.uk)
  • Some people have neither XY nor XX chromosomes - for example, they may only have one X chromosome (XO), or they may have an extra chromosome (XXY). (ballysillangrouppractice.co.uk)
  • In females, both sex chromosomes are X chromosomes (XX), while in males, there is one X and one Y chromosome (XY). (medindia.net)
  • Klinefelter s Syndrome occurs as the result of an error during the formation of an egg or a sperm that results in a person having a XXY combination or 47 chromosomes instead of the normal 46. (medindia.net)
  • The sex chromosomes are labeled X and Y. Karyotyping is useful in determining the presence of chromosome defects. (thefreedictionary.com)
  • Cytogenetic disorders with visible chromosomal abnormalities are evidenced by either an abnormal number of chromosomes or some alteration in the structure of one or more chromosomes. (thefreedictionary.com)
  • Either trisomy or monosomy involving the sex chromosomes yields relatively mild abnormalities. (thefreedictionary.com)

chromosomal

  • Klinefelter's Syndrome (KS) is a sex chromosomal disorder like Turner s syndrome. (medindia.net)
  • Klinefelter's Syndrome, which affects 1 in 500 to 1 in 1000 live births, is a sex chromosomal genetic disorder where the affected males have an extra X chromosome. (medindia.net)
  • The prevalence of chromosomal disorders cannot be fully and accurately determined because many of these disorders do not permit full embryonic and fetal development and therefore end in spontaneous abortion. (thefreedictionary.com)

Reversal

  • Diseases associated with AKR1C4 include 46Xy Sex Reversal 8 and Prostate Cancer . (genecards.org)
  • Defects in NR0B1 are the cause of 46,XY sex reversal type 2 (SRXY2) [MIM: (abcam.cn)
  • Genes within the dosage-sensitive sex reversal region are, therefore, not essential for testis development, but, when present in a double dose, interfere with testis formation. (abcam.cn)

androgen

  • Partial androgen insensitivity syndrome (PAIS) is a disorder of sex development that affects the growing reproductive and genital organs of a fetus. (nih.gov)
  • One possible cause is androgen insensitivity syndrome (AIS) , where the body ignores androgens or is insensitive to them, so external development is female. (ballysillangrouppractice.co.uk)
  • Adrenal androgen precursors are converted in the gonads and peripheral target cells to sex steroids that act via nuclear androgen and estrogen receptors. (mhmedical.com)
  • With the exception of 46,XX individuals with CAH or documented maternal androgen excess, most patients with genital ambiguity require surgical exploration for diagnostic confirmation and removal of contradictory gonadal tissue. (medscape.com)

androgens

genes

  • This occurs because of a difference with your genes and/or how you respond to the sex hormones in your body. (ballysillangrouppractice.co.uk)
  • See also 'Mutant p53: one name, many proteins' by William A. Freed-Pastor and Carol Prives, in Genes and Development, 2012, Volume 26, 1268-86. (edwardbetts.co.uk)

normally

  • Their sex organs are normally either male or female, but they may not go through normal sexual development at puberty. (ballysillangrouppractice.co.uk)

reproductive

  • Find out about disorders of sex development (DSDs), a group of rare conditions where the reproductive organs and genitals don't develop as expected. (ballysillangrouppractice.co.uk)
  • Although gender assignment in the newborn period should be based on the individual's potential for normal sexual function and the potential for future reproductive function, most cases of ovotesticular disorder of sexual development are diagnosed during the adolescent period. (medscape.com)

Deficiency

  • Disorders of the adrenal cortex are characterized by deficiency or excess of one or several of the three major corticosteroid classes. (mhmedical.com)

gonadal

  • Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. (abcam.cn)
  • HHG is a condition resulting from or characterized by abnormally decreased gonadal function, with retardation of growth and sexual development. (abcam.cn)
  • Ovotesticular disorder of sexual development can only be confirmed with gonadal biopsy results. (medscape.com)
  • It allows preservation of gonadal tissue concordant with sex of rearing, and removal of all discordant tissue. (medscape.com)

hormone

  • This can mean they don't produce enough testosterone, the sex hormone responsible for the development of male characteristics and important for maintaining bone strength, sex drive and fertility in men. (ballysillangrouppractice.co.uk)
  • Sex hormone replacement might be required for those with pubertal delay. (medscape.com)

fertility

  • This should be performed to allow for maximal gender-specific development and to increase fertility potential. (medscape.com)

adrenal gland

  • XL-AHC is a developmental disorder of the adrenal gland that results in profound hormonal deficiencies and is lethal if untreated. (abcam.cn)

normal

  • Sex may also be difficult because the vagina is shorter than normal. (ballysillangrouppractice.co.uk)
  • Normal sexual development is seen in infancy and childhood. (medindia.net)
  • Although the onset of puberty is not delayed, the post-pubertal developments are inadequate in comparison to normal males. (medindia.net)
  • But now we're seeing people who don't even want it listed as a disorder, they want it listed as just a normal thing. (fark.com)

genetic

  • Monosomy involving an autosome usually results in the loss of too much genetic information to permit sufficient fetal development for a live birth. (thefreedictionary.com)

embryonic

  • May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency. (abcam.cn)

demonstrate

  • These skills demonstrate Donald's level of __________ development. (studystack.com)

type

cognitive

  • Physical, cognitive, psychosocial development are what social scientists call the three __________ of the self. (studystack.com)
  • Standardized ginkgo leaf extracts, such as EGb 761 ( Tebonin forte , Schwabe), have been used in clinical trials for cognitive and circulatory disorders at daily doses of 120 to 240 mg of extract. (drugs.com)

sexual development

  • Because most cases of ovotesticular disorder of sexual development are diagnosed during adolescence, gender usually is not reassigned. (medscape.com)

individuals

  • More severely affected individuals may have female external genitalia with an abnormally large clitoris, partial fusion of the labia and gynecomastia (excessive development of male breasts). (nih.gov)
  • Note=XY individuals with a duplication of part of the short arm of the X chromosome and an intact SRY gene develop as females. (abcam.cn)

syndrome

  • Although most patients with Klinefelter's Syndrome have only one extra X chromosome in their cells, approximately 10% of the patients have different forms of the disorder. (medindia.net)

example

  • This is an example of the interaction between which two types of development? (studystack.com)
  • The invention enables non-invasive prenatal diagnosis including for example sex determination, blood typing and other genotyping, and detection of pre-eclampsia in the mother. (google.ca)

condition

people

  • People who feel they are the wrong sex are driven crazy by people like you, usualy in their own family. (fark.com)
  • As posted elsewhere, we have disorders in the mind that make people insist that they are an amputee and their limbs aren't supposed to be there. (fark.com)

changes

  • A preschool program that is designed to focus on the change and stability in a child's mental abilities constantly notes changes in the child's __________ development. (studystack.com)
  • I can't recall wtf it was but sex changes were a one hour through=patient operation. (fark.com)

child

  • Child development is the scientific study of the processes that human beings undergo from the moment of conception through adolescence. (studystack.com)
  • Dietrich Tiedemann and Charles Darwin used the information obtained from __________ to support their early theories about child development. (studystack.com)

frequently

  • Hypogonadotropic hypogonadism (HHG) is frequently associated with this disorder. (abcam.cn)

given

  • A __________ is a specific time during development when a given event, or lack of an event, has the greatest impact. (studystack.com)

removal

  • The treatment may entail removal of my hand if no other option came up, but it is still a disorder. (fark.com)

delay

  • Sometimes there is dyslexia, delay in speech and development. (medindia.net)

events

  • autoimmune disorders, infection, infarction, or by iatrogenic events such as surgery or hormonal suppression. (mhmedical.com)