The stimulus properties of 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxymethamphetamine (MDMA) and several related compounds were compared to those of (+)-lysergic acid diethylamide (LSD) and mescaline (3,4,5-trimethoxyphenylethylamine) in a two-lever, water-reinforced, drug discrimination task. (erowid.org)
Phenethylamine3
The 2C is because its had a 2-carbon chain sticking off of the phenyl ring (which is why its a phenethylamine instead of an amphetamine), and I *assume* the B is because of the Br atom in the 4 position. (erowid.org)
2,5-Dimethoxy-4-methyl-amphetamine (STP): A New Hallucinogenic Drug" (PDF). (wikipedia.org)
A solution of 0.7 g 1-(2,5-dimethoxyphenyl-4-methyl)-2-propanone in 20 mL MeOH was treated with 6.0 g ammonium acetate, 0.3 g sodium cyanoborohydride, and 3 g Linde 3 A molecular sieves. (drugwiki.net)
The main active alkaloids are 1-methoxy-Demerol (1-Methyl-1-(4-hydroxy-7-yl)-Demerol), 7-, 8-Hydroxy-Demerol (7,8-di-Methoxy-Demerol and 2,3-methylenedioxy-Demerol (2,3-methylenedioxy-Demerol). (structuraldesignsolutions.com.au)
After standing at room temperature for 2 h, the crystalline 2,5-dimethoxy-4-methylamphetamine hydrochloride (DOM) was removed by filtration, washed with Et2O, and air dried to constant weight. (drugwiki.net)
2,5-Dimethoxy-4-methylamphetamine (also known as 2C-E , or colloquially as "Aquarust" and "Eternity") is a psychedelic substance and a substituted amphetamine. (anyrawchem.com)
20171
آخر تعديل لهذه الصفحة كان يوم 4 فبراير 2017، الساعة 11:13. (arabsciencepedia.org)
Agonist2
DOM is a selective 5-HT2A, 5-HT2B, and 5-HT2C receptor partial agonist. (wikipedia.org)
Central and peripheral injections of the 5-HT2 agonist, 1-2,5-dimethox. (erowid.org)
Methoxy3
Analogues where the methoxy groups at the 2,5- positions of the aromatic ring have been altered have also been synthesised and tested as part of an effort to identify the binding mode of DOM at the 5-HT2A receptor. (wikipedia.org)
Both the 2- and 5- O-desmethyl derivatives 2-DM-DOM and 5-DM-DOM, and the 2- and 5- ethyl analogues 2-Et-DOM and 5-Et-DOM have been tested, but in all cases were significantly less potent than the corresponding methoxy compound, showing the importance of the oxygen lone pairs in 5-HT2A binding. (wikipedia.org)
The drugs 2-, 3-, and 4-methoxy-N-methylamphetamine, 3-methoxy-4,5-methylenedioxy-N-methylamphetamine and 3,4-methylenedioxy-N-methylamphetamine are identified by spectroscopic techniques. (erowid.org)
Derivatives2
The analytical properties of these compounds are compared with the structurally similar 3,4-methylenedioxyamphetamine (MDA) derivatives, a popular series of drugs of abuse. (erowid.org)
The primary amine (MDP-2-B) and the N-substituted derivatives of MDP-2-B are separated by reversed-phase liquid chromatography under acidic mobile-phase conditions. (erowid.org)
Receptor2
Its psychedelic effects are mediated by its agonistic properties at the 5-HT2A receptor. (wikipedia.org)
Due to its selectivity, DOM is often used in scientific research when studying the 5-HT2 receptor subfamily. (wikipedia.org)
Methadone1
Inability of methadone to prevent the depletion of brain 5-hydroxyindo. (erowid.org)
Doses1
Doses are 12-24 mg, Duration is 4-8 hours. (erowid.org)
Ethyl2
The 2,6-dimethoxy positional isomer of DOM, known as Ψ-DOM, is also mentioned in PiHKAL as being active, as is the alpha-ethyl homologue Ariadne. (wikipedia.org)
The compounds are not completely resolved by gas chromatography on an HP-1 phase, and the separation is complicated by extensive thermal degradation of the N-hydroxy derivative (MDP-2-OHB). (erowid.org)
Compounds of the HMDA series have UV absorption properties similar to the MDAs because both series contain the same 3,4-methylenedioxyphenyl chromophore. (erowid.org)
STP was first synthesized and tested in 1963 by Alexander Shulgin, who was investigating the effect of 4-position substitutions on psychedelic amphetamines. (wikipedia.org)
Yet if you are given 5 dried grams of magic mushrooms or DMT or some other potent psychedelic, whoever you are, a freight train of significance is going to be coming your way in a matter of moments. (goodmedicine.org.uk)
2,5-Dimethoxy-4-methylamphetamine (2C-E) is a psychedelic substance, member of the 2C-x family of psychedelic phenethylamines. (anyrawchem.com)
Homologue1
This is the 2 carbon homologue of DOM (2C-B is to DOB as 2C-D is to DOM). (erowid.org)
To a solution of 54.9 g 2,5-dimethoxy-4-methylbenzaldehyde (see the recipe for 2C-D for its preparation) in 215 g glacial acetic acid there was added 19.5 g anhydrous ammonium acetate and 30.6 g nitroethane. (drugwiki.net)
As much H2O as possible was added (just short of a persistant cloudy oily character) and after a few additional h standing, the crystalline 1-(2,5-dimethoxy-4-methylphenyl)-2-nitropropene was removed by filtration and recrystallized from boiling acetic acid. (drugwiki.net)
To a well stirred suspension of 10.4 g powdered iron in 20 mL glacial acetic acid held at reflux temperature, there was added 4.9 g 1-(2,5-dimethoxy-4-methylphenyl)-2-nitropropene as a solid. (drugwiki.net)
The actions of d-lysergic acid diethylamide (L.S.D. 25).Part 2. (erowid.org)
The 1-(3,4-methylenedioxyphenyl)-3-butanamines (HMDAs) are prepared via reductive amination of the corresponding ketone with a series of low molecular weight alkylamines. (erowid.org)
Three regioisomeric 3,4-methylenedioxyphenethylamines having the same molecular weight and major mass spectral fragments of equivalent mass have been reported as components of clandestine drug samples in recent years. (erowid.org)
Ecstasy1
Accidental ingestion of 'Ecstasy' (3,4-methylenedioxymethylamphetamine. (erowid.org)
Hours1
2C-D has a potency of 20-60 mg and a duration of 4-6 hours. (erowid.org)
Effects3
Pharmacological and Toxicological Effects of B-3,4-Methylenedioxyamphe. (erowid.org)
Cardiovascular and neuroendocrine effects and pharmacokinetics of 3, 4. (erowid.org)
Cardiovascular Effects of 3,4-Methylenedioxymethamphetamine. (erowid.org)
Effect1
LSD: Its effect upon 5-hydroxytryptamine in embryonic development of X. (erowid.org)
Suspension2
A suspension of 9.5 g LAH in 750 mL well stirred anhydrous Et2O was held at reflux under an inert atmosphere, with the return of the condensed solvent passing through a Soxhlet thimble containing 9.5 g 1-(2,5-dimethoxy-4-methylphenyl)-2-nitropropene. (drugwiki.net)
After the addition of the nitrostyrene was complete, the stirred suspension was maintained at reflux for an additional 4 h, then cooled to room temperature and allowed to continue stirring overnight. (drugwiki.net)