• amino acid
  • It was reported that tandem amino acid repeats have many functions of stabilizing proteins [ 1 ], maintaining conformation [ 2 ], elevating activity, and increasing half-life of proteins in blood or tissues. (hindawi.com)
  • Following the leucine rich repeat domain is the acidic residue-rich sequence containing sulfated tyrosines, the highly O-glycosylated macroglycopeptide, a stalk region of about 40 to 50 residues, a single transmembrane sequence and finally a cytoplasmic tail containing 96 amino acid residues which includes serine residues such as Ser587, Ser590 and Ser609 that can be phosphorylated. (wikipedia.org)
  • allele
  • These data are therefore a virtually irrefutable demonstration of the reality of race - a purely statistical analysis of allele frequencies [genetic differences from one group to another] gives results that are essentially identical to the racial groupings established by traditional anthropology. (amren.com)
  • ribosomal
  • To resolve a well-supported eumalacostracan phylogeny and obtain a robust tree, it will be necessary to look beyond the most commonly utilized sources of data (nuclear ribosomal and mitochondrial sequences). (wikipedia.org)
  • Ribosomal DNA (rDNA) is a DNA sequence that codes for ribosomal RNA. (wikipedia.org)
  • genes
  • Also, simple sequence repeats were found in the transcriptome with many linked to terpene pathway genes including the genes potentially involved in aroma biosynthesis. (frontiersin.org)
  • 1999). "Prediction of the coding sequences of unidentified human genes. (wikipedia.org)
  • For example, small RNA viruses infecting animals (picornaviruses) and those infecting plants (cowpea mosaic virus) were compared and turned out to share significant sequence similarity and, in part, the order of their genes. (wikipedia.org)
  • The four genes that code for the components of the receptor in humans have a simple organization in which the coding sequence is contained within a single exon. (wikipedia.org)
  • 1995
  • The United Kingdom's National DNA Database (NDNAD) was set up in 1995 using the Second Generation Multiplex (SGM) DNA profiling system (SGM+ DNA profiling system since 1998). (wikipedia.org)
  • The first complete genome sequence of a cellular organism, that of Haemophilus influenzae Rd, was published in 1995. (wikipedia.org)
  • expansions
  • Many human diseases have been reported to be associated with trinucleotide repeat expansions including Huntington's disease. (wikipedia.org)
  • copies
  • In this study, T α 1 which was composed of three repeated copies of T α 1 was fuse-expressed with thioredoxin (trx) in E. coli TOP10 strain and purified by heat treatment and Q-Sepharose Fast Flow ion-exchange chromatography. (hindawi.com)
  • Each set is measured and the number of repeat copies is recorded. (wikipedia.org)
  • motifs
  • The new method utilizes known LRR structures to recognize and align new LRR motifs in TLRs and incorporates multiple sequence alignments and secondary structure predictions. (biomedcentral.com)
  • Each of the six major TLR families is characterized by their constituent LRR motifs, their repeat numbers, and their patterns of cysteine clusters. (biomedcentral.com)
  • phylogenetic analysis
  • Mining of transcriptome data and subsequent phylogenetic analysis led to identification of terpene synthases, pyrophosphatases, alcohol dehydrogenases, aldo-keto reductases, carotenoid cleavage dioxygenases, alcohol acetyltransferases, and aldehyde dehydrogenases, which are potentially involved in essential oil biosynthesis. (frontiersin.org)
  • In cases for sibling species, comparison of the rDNA segment including ITS tracts among species and phylogenetic analysis are made satisfactorily. (wikipedia.org)
  • replication
  • When DNA polymerase encounters a direct repeat, it can undergo a replication slippage. (wikipedia.org)
  • Slippage occurs through five main stages: In the first step, DNA polymerase encounters the direct repeat during the replication process. (wikipedia.org)
  • DNA polymerase reassembles its position on the template strand and resumes normal replication, but during the course of reassembling, the polymerase complex backtracks and repeats the insertion of deoxyribonucleotides that were previously added. (wikipedia.org)
  • Tandem repeats (the main influence for slippage replication) can be found in coding and non-coding regions. (wikipedia.org)
  • Inverted repeats are principally found at the origins of replication of cell organism and organelles that range from phage plasmids, mitochondria, and eukaryotic viruses to mammalian cells. (wikipedia.org)
  • The replication origins of the phage G4 and other related phages comprise a segment of nearly 139 nucleotide bases that include three inverted repeats that are essential for replication priming. (wikipedia.org)
  • strains
  • Novel insights into the genomic basis of citrus canker based on the genome sequences of two strains of Xanthomonas fuscans subsp. (ufl.edu)
  • licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative C ommons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestri cted use, distributi on, and reproductio n in any medium, provided the original work is properly cited.Research articleNovel insights into the genomic basis of citrus canker based on the genome sequences of two strains of Xanthomonas fuscans subsp. (ufl.edu)
  • Genotypically identical strains (sequence type ST8, spa -type t024, MLVA-type 4698, enterotoxin A FRI100) were isolated in 10 patients, shiitake mushrooms, cured ham, and in three members of staff. (eurosurveillance.org)
  • Non-enterotoxigenic strains with livestock-associated sequence type ST398 were isolated from three food items and two members of staff. (eurosurveillance.org)
  • 1989
  • The creation of a national DNA database within the U.S. was first mentioned by the Technical Working Group on DNA Analysis Methods (TWGDAM) in 1989. (wikipedia.org)
  • strand
  • The newly synthesized strand then detaches from the template strand and pairs with another direct repeat upstream. (wikipedia.org)
  • This results in some repeats found in the template strand being replicated twice into the daughter strand. (wikipedia.org)
  • evolutionary
  • The old algorithm is limited in its application because there are many overlaps between different repeat units which result in false evolutionary relationships. (biomedcentral.com)
  • The different coding regions of the rDNA repeats usually show distinct evolutionary rates. (wikipedia.org)
  • polymerase
  • Retrotransposons are commonly grouped into three main orders: TEs with long terminal repeats (LTRs), which encode reverse transcriptase, similar to retroviruses Long interspersed nuclear elements (LINEs, LINE-1s, or L1s), which encode reverse transcriptase but lack LTRs, and are transcribed by RNA polymerase II Short interspersed nuclear elements do not encode reverse transcriptase and are transcribed by RNA polymerase III [Note : Retroviruses can also be considered TEs. (wikipedia.org)
  • bacterial
  • Furthermore, the super-repeat in the TLR7 family suggests strongly that "bacterial" and "typical" LRRs evolved from a common precursor. (biomedcentral.com)
  • transposons
  • They define the boundaries in transposons and indicate regions capable of self-complementary base pairing (regions within a single sequence which can base pair with each other). (wikipedia.org)
  • Terminal inverted repeats have been observed in the DNA of various eukaryotic transposons, even though their source remains unknown. (wikipedia.org)
  • present
  • Frasch and colleagues suggested that tandem repeats present in Trypanosoma cruzi transsialidase stabilized the catalytic activity. (hindawi.com)
  • In addition, repeats present on T . cruzi shed proteins increased trans-sialidase half-life in blood from 7 to almost 35 h [ 3 ]. (hindawi.com)
  • The present invention relates to parallel genotyping (or other sample analysis) of multiple patients by direct sample immobilization onto microspheres of an array. (google.ca)
  • The present invention is directed to materials and methods for the identification and analysis of intermediate tandem repeat sequences in DNA, wherein an intermediate tandem repeat (ITR) sequence is a region of a DNA sequence containing at least one five to seven base repeat unit appearing in tandem. (google.com.au)
  • Only in samples in which the gammabacterial clade SAR86 was present more than 1% non-Legionella sequences were observed. (biomedcentral.com)
  • However, an affected individual will have 36- 121 repeats present. (wikipedia.org)
  • As many as 21 of these long repeats can be present, accounting for 230 kDa of the total mass and two-thirds of the filamentous region. (wikipedia.org)
  • platelet
  • The concomitant expression of all three subunits is required to allow the effective expression of GPIb-IX on the platelet cell surface and analysis of receptor expression in transfected Chinese hamster ovary (CHO) cells has further supported that the interaction between these subunits also acts to stabilize them. (wikipedia.org)
  • Thus
  • Thus, recombination occurring at a pair of inverted sites will invert the DNA sequence between the two sites. (wikipedia.org)
  • chromosome
  • 1998). "Report of the Third International Workshop on Y Chromosome Mapping 1997. (wikipedia.org)
  • Very stable chromosomes have been observed with comparatively fewer numbers of inverted repeats than direct repeats, suggesting a relationship between chromosome stability and the number of repeats. (wikipedia.org)
  • distinct
  • The limited recombination of the sequences between two distinct sequence elements known as conservative site-specific recombination (CSSR) results in inversions of the DNA segment, based on the arrangement of the recombination recognition sequences on the donor DNA and recipient DNA. (wikipedia.org)
  • locus
  • An individual who is not affected by Huntington's disease will have 6-35 tandem repeats at the HD locus. (wikipedia.org)
  • If both strands, inherited from the parents, contain the same number of repeats at that locus the person is said to be homozygous at that locus. (wikipedia.org)
  • widely
  • They are widely used for DNA profiling in cancer diagnosis, in kinship analysis (especially paternity testing) and in forensic identification. (wikipedia.org)