• The HFCS used in soft drinks has been shown to contain a higher fructose-to-glucose ratio than previously thought. (biomedcentral.com)
  • Apple juice naturally contains a high (≥2:1) fructose-to-glucose ratio. (biomedcentral.com)
  • Given these results, prior research and case-study evidence, it is reasonable to suggest that the two-fold higher asthma risk associated with 100% juice consumption is due to apple juice's high fructose-to-glucose ratio, and that the ~ 2.5/~ 3.5 times higher risk associated with soda/sports/fruit drinks intake is with the excess-free-fructose in HFCS. (biomedcentral.com)
  • Excess-free-fructose is fructose which occurs when the fructose-to-glucose ratio exceeds 1:1, as in HFCS and apple juice. (biomedcentral.com)
  • Most natural foods have a 1:1 fructose-to-glucose ratio. (biomedcentral.com)
  • When a combination of carbohydrates is ingested (e.g., glucose and fructose) oxidation rates of slightly more than 100 g/h can be achieved if large amounts of carbohydrate are ingested (e.g. (gssiweb.org)
  • Fructose 1,6-diphosphatase (FDPase) (also termed fructose 1,6-bisphosphatase) is a focal enzyme in gluconeogenesis via its conversion of fructose 1,6-diphosphate (FDP) to fructose 6-phosphate (F-6-P), which permits endogenous glucose production from gluconeogenic amino acids (eg, alanine and glycine), glycerol, or lactate. (medscape.com)
  • The fructose and glucose concentrations did not vary significantly, while the content of total soluble solids increased during both storage regimes. (frontiersin.org)
  • These levels are 0.1 g/L for Glucose + Fructose, and 0.05 g/L for malic acid. (awri.com.au)
  • Several other promising scientific studies now show that lipoic acid has a beneficial effect on a number of the factors involved in metabolic syndrome: it reduces triglyceride levels, lowers cholesterol, improves fasting plasma glucose, and causes weight loss in rodent models of obesity. (lifeextension.com)
  • Introduction of heterologous glucose- or fructose-proton symporters in an hxt 0 yeast background strain (derived from CEN.PK2-1C) restored growth on the corresponding sugar under aerobic conditions. (biomedcentral.com)
  • To apply this strategy to increase the ethanol yield on sucrose, we constructed a platform strain in which all genes encoding hexose transporters, disaccharide transporters and disaccharide hydrolases were deleted, after which a combination of a glucose-proton symporter, fructose-proton symporter and extracellular invertase ( SUC2 ) were introduced. (biomedcentral.com)
  • Coimmobilization of glycoamilase and glucose isomerase for one-step conversion of dextran to fructose. (scialert.net)
  • Fasting hypoglycaemia and metabolic acidosis associated with deficiency of hepatic fructose-1,6-diphosphatase activity. (medscape.com)
  • Fatal hepatic or renal injury following ingestion of fructose has been reported in these patients. (medscape.com)
  • Insufficient hepatic O 2 in animal and human studies has been shown to elicit a hepatorenal reflex in response to increased hepatic adenosine, resulting in the stimulation of renal as well as muscle sympathetic nerve activity and activating the renin angiotensin system. (surgicalneurologyint.com)
  • Hepatic fructose metabolism rapidly consumes ATP resulting in increased adenosine production and hyperuricemia as well as elevated renin release and sympathetic activity. (surgicalneurologyint.com)
  • For instance, in rats fed with fructose, hepatic AR is significantly upregulated, which is associated with impaired activation of Stat3 and suppressed activity of PPAR α in the liver [ 9 ]. (hindawi.com)
  • Recent research provides consistent evidence that the unexplained doubling of childhood asthma prevalence (1980-1995), its continued climb and 2013 plateau, may be associated with the proliferation of high-fructose-corn-syrup (HFCS) in the US food supply. (biomedcentral.com)
  • These subsidies have artificially lowered the cost of corn, and henceforth, products containing corn, such as HFCS (High Fructose Corn Syrup). (liberaterva.com)
  • The aim of this study was to investigate the influences of fermentable and commonly used unfermentable sugars, usually added during wort boiling to increase the beer's palate fullness, on oxidative processes during wort boiling, the SO 2 formation, palate fullness, flavor, and formation of specific aging compounds. (asbcnet.org)
  • These include small numbers of intake studies, differing approaches to analysing carbohydrate, a variety of terms used to describe sugars intakes and a dearth of information about starch intakes. (nature.com)
  • In this study, the facilitated diffusion transport system for hexose sugars of S. cerevisiae was replaced by hexose-proton symport. (biomedcentral.com)
  • Results from this study suggest applications that can be applied in other biological systems containing free amino acids and sugars. (peanutscience.com)
  • Patients with FDPase deficiency typically present in the newborn period with symptoms or signs related to hypoglycemia and metabolic acidosis following ingestion of fructose. (medscape.com)
  • Human fructose-1,6-bisphosphatase gene (FBP1): exon-intron organization, localization to chromosome bands 9q22.2-q22.3, and mutation screening in subjects with fructose-1,6-bisphosphatase deficiency. (medscape.com)
  • Herzog B, Morris AA, Saunders C, Eschrich K. Mutation spectrum in patients with fructose-1,6-bisphosphatase deficiency. (medscape.com)
  • Identification of genetic mutations in Japanese patients with fructose-1,6-bisphosphatase deficiency. (medscape.com)
  • Enzyme deficiency decreases the rate of conversion of fructose-6-phosphate to fructose-1,6-diphosphate. (medscape.com)
  • Our bodies make oxalate as an end product of metabolism (primarily the metabolism of the protein amino acids glycine and serine, but also of vitamin C and possibly fructose). (veganhealth.org)
  • Regulation of metabolism: biochemical and genetic studies. (mpg.de)
  • The application of transgenic technology to the study of sink metabolism in potato. (mpg.de)
  • When challenged with D-fructose, patients lacking FDPase accumulate intrahepatocellular FDP, which inhibits gluconeogenesis and, if intracellular phosphate stores are depleted, inhibits glycogenolysis. (medscape.com)
  • After qualifying as a certified technician in preservation engineering (1991-1993), Thomas Kunz completed his basic studies in chemistry at the University of Applied Sciences, Isny (1994-1995), and his basic studies in food chemistry at Wuppertal University (1995-1998), before studying food technology at the University of Applied Sciences, Trier (1998-2002). (asbcnet.org)
  • Aspartame toxicity is often overlooked as a disease even though it has been reported countless times to independent organizations and scientists (Mission Possible 1994, Stoddard 1995). (utopiasilver.com)
  • Patients develop severe hypoglycemia with metabolic acidosis upon ingestion of fructose. (medscape.com)
  • 26 120 180 ] Body mass index (BMI) has been widely used to indicate the level of obesity, though recent studies have found that abdominal or visceral adiposity (vs subcutaneous), as reflected in the waist-to-hip ratio or waist circumference, is a strong criteria for predicting the risk of developing metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM). (surgicalneurologyint.com)
  • 17, 2020 Consuming high fructose corn syrup appears to be as bad for your health as consuming sugar in the form of fructose alone, according to a new study. (sciencedaily.com)
  • Unabsorbed excess-free-fructose in the gut may react with dietary proteins to form immunogens that bind asthma mediating receptors, and/or alter the microbiota towards a profile linked to lung disorders. (biomedcentral.com)
  • 19 Skoog S M, Bharucha A E. Dietary fructose and symptoms: a review. (thieme-connect.de)
  • Ingredients supplier Archer Daniels Midland (ADM) said on Thursday that it had reached a $400 million (€333m) settlement in an anti-trust case that claimed the US firm conspired to fix the price of the food sweetener high fructose corn syrup used expansively in food and soft drink products. (foodnavigator.com)
  • High fructose syrups, known as isoglucose in Europe, kicked off in the US in the 1970s when the country developed new technologies to process this bulk calorific sweetener. (foodnavigator.com)
  • A recent study ​ found that in the 20 years from 1970 to 1990 the consumption of the popular soft drink sweetener, high fructose corn syrup, leapt by a massive 1000 per cent. (foodnavigator.com)
  • Summary: Washed cells of Agrobacterium radiobacter prepared from a fructose-limited continuous culture (D 0.045 h -1 ) transported D-[U -14 C]fructose in a linear manner for up to 4 min at a rate several-fold higher than the rate of fructose utilization by the growing culture. (microbiologyresearch.org)
  • The national estimates produced from these studies describe the utilization of hospital ambulatory medical care services in the United States. (cdc.gov)
  • Thus, children have received high excess-free-fructose doses, the fructose type associated with fructose malabsorption. (biomedcentral.com)
  • People who eat a diet high in fructose, in the form of added sugar, are at increased risk of developing high blood pressure, or hypertension, according to a new study. (sciencedaily.com)
  • People who eat a diet high in fructose, in the form of added sugar, are at increased risk of developing high blood pressure, or hypertension, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN) . (sciencedaily.com)
  • Our study identifies a potentially modifiable risk factor for high blood pressure. (sciencedaily.com)
  • Ignited in the early 1990s the proposed settlement has its roots in a law case filed by over 20 plaintiffs, including soft drink giants Coca-Cola and PepsiCo, that accused the agribusiness of linking up with other manufacturers to fix prices of the sugar substitute, high-fructose corn syrup. (foodnavigator.com)
  • The monomeric protein (M r 34200 by SDS-PAGE and 37700 by gel-filtration FPLC) bound D-[U -14 C]-fructose stoichiometrically (1.17 nmol nmol FBP -1 ) and with high affinity (K D 0.49 μM) as shown by equilibrium dialysis. (microbiologyresearch.org)
  • The recent documentation of the very high potential of the sugar palm ( Borassus flabellifer) as a source of digestible energy for pig production (Khieu Borin and Preston 1995) has focussed attention on the palm species in general and their multi-purpose uses in particular. (cipav.org.co)
  • This theoretical concept is supported by experimental results in animals fed a high fructose diet to induce MetS. (surgicalneurologyint.com)
  • In this study, we found that high expression of GFAT1 was significantly associated with serum alpha-fetoprotein (AFP), serum alanine aminotransferase (ALT), tumor size, tumor encapsulation, T stage and TNM stage. (oncotarget.com)
  • The results of this study suggest that sugary drink consumption was associated with body weight gain among young children with high predisposition for future overweight. (cambridge.org)
  • Easy carbohydrates like high fructose corn syrup put a huge strain on insulin-producing cells in the pancreas. (utopiasilver.com)
  • Snack companies and fast food chains scramble to keep their businesses alive, introducing products with lower levels of high fructose corn syrup and saturated fats, marketed as "a safer snack. (splicetoday.com)
  • CONCLUSIONS: Nine influencing factors and a predictive model were proposed in this study, which could identify women who are at high risk of developing AUB-O. This finding highlights the importance of early screening and the lifelong management of ovulatory disorders for women. (bvsalud.org)
  • It is concluded that fructose is transported into A. radiobacter and related organisms via a periplasmic fructose/mannose-binding-protein-dependent active-transport system, in contrast to the phosphotransferase system used by many other species of bacteria. (microbiologyresearch.org)
  • Thankfully, studies have already shown that there are specific bacteria that are as effective as the drug and have no side effects. (vitanetonline.com)
  • Gibson & Roberfroid (1995) defined a prebiotic as a nondigestible food ingredient that beneficially affects the host by selectively stimulating the growth and activity of one or a limited number of bacteria in the gut, and thus improving host health. (scielo.org.za)
  • In vitro studies also revealed that GFAT1 promoted the proliferation, cell cycle progression, migration and invasion of HCC cells. (oncotarget.com)
  • Dr. Jalal's team found that people who consumed a diet of 74 grams or more per day of fructose (corresponding to 2.5 sugary soft drinks per day) had a 26%, 30%, and 77% higher risk for blood pressure levels of 135/85, 140/90, and 160/100 mmHg, respectively. (sciencedaily.com)
  • The aim of the present study was to examine the associations of sugary drink consumption and its substitution with alternative beverages with body weight gain among young children predisposed to future weight gain. (cambridge.org)
  • el-Maghrabi MR, Gidh-Jain M, Austin LR, Pilkis SJ: Isolation of a human liver fructose-1,6-bisphosphatase cDNA and expression of the protein in Escherichia coli. (drugbank.com)
  • The points in the figures showing no-observed-adverse-effect levels (NOAELs) or lowest-observed-adverse-effect levels (LOAELs) reflect the actual doses (levels of exposure) used in the studies. (cdc.gov)
  • Therefore, we tested the hypothesis that excess-free-fructose intake is associated with childhood asthma risk. (biomedcentral.com)
  • If you have a history of calcium-oxalate kidney stones or suspect you have hyperoxaluria, there are a few more things you can do such as limit oxalate as much as possible, add citrate to your diet (through orange or lemon juice, or calcium citrate), minimize added fructose and sodium, or try a probiotic supplement as described below. (veganhealth.org)
  • However, well-planned prospective randomized clinical studies need to be completed to see if low fructose diets will prevent the development of hypertension and its complications," said Dr. Jalal. (sciencedaily.com)
  • In the first study, diets containing 0 or 0.2% AOS (dry matter basis) were incubated for 24, 48 and 72 h with ruminal fluid to evaluate the in vitro dry matter disappearance (IVDMD) and fermentation characteristics. (scielo.org.za)
  • Cows were randomly assigned to the diets tested in the in vitro study. (scielo.org.za)
  • In this study the addition of AOS to dairy cow diets was investigated by measuring its influence on the in vitro dry matter disappearance (IVDMD) and in vitro fermentation of the diet, and this was followed by a study on its effect on milk production and of lactating dairy cows and the composition of the milk. (scielo.org.za)
  • In 1964, a group of 10 experts appointed by the Surgeon General issue a report that summarizes all existing studies on energy-dense, large-portion diets linked to obesity and declare them a health hazard to the American public. (splicetoday.com)
  • To examine whether increased fructose consumption has contributed to rising rates of hypertension, Diana Jalal, MD (University of Colorado Denver Health Sciences Center) and her colleagues analyzed data from the National Health and Nutrition Examination Survey (2003-2006). (sciencedaily.com)
  • In contrast, fructose possesses a higher ability to generate the open-chain-structure, resulting in stronger reducing properties. (asbcnet.org)
  • Prolonged growth of A. radiobacter in fructose-limited continuous culture led to the selection of a novel strain (AR100) which overproduced a fructose-binding protein (FBP) and showed an increased rate of fructose transport. (microbiologyresearch.org)
  • Moreover, the sugar-negative platform strain constructed in this study acts as a valuable starting point for future studies on sugar transport or development of cell factories requiring specific sugar transport mechanisms. (biomedcentral.com)
  • Abstract Background Most studies focused on the benefits of lycopene on serum lipids but no studies have been specifically designed to assess the role of a tomato sauce from vine-ripened tomatoes on patients affected by polygenic hypercholesterolemia. (researchgate.net)
  • The unprecedented doubling of childhood asthma prevalence from 1980 to 1995, its continued climb and 2013 plateau, mainly due to plateauing prevalence among non-Hispanic black children [ 1 ], has been described by the US Center for Disease Control (CDC) as mysterious [ 2 ]. (biomedcentral.com)
  • Obesity has been ruled out as a cause, as a recent CDC study found that the unexplained rise in asthma prevalence was among normal weight children [ 3 ]. (biomedcentral.com)
  • Study participants answered questions related to their consumption of foods and beverages such as fruit juices, soft drinks, bakery products, and candy. (sciencedaily.com)
  • A large number of clinical studies have demonstrated that a significant percentage of patients with MetS have durable remission of comorbidities within days of bariatric surgery, calorie restriction (diet), or implantation of an endoluminal plastic sleeve that prevents nutrient contact with the proximal gastrointestinal mucosa, as discussed below. (surgicalneurologyint.com)
  • Over 15 randomized clinical studies have shown that intravenous administration of 300-600 mg of lipoic acid a day greatly improves nerve function and relieves pain symptoms in diabetic neuropathy patients. (lifeextension.com)
  • Researchers are striving to identify environmental factors that might be responsible for the development of hypertension, and they suspect that fructose may play a role. (sciencedaily.com)
  • I suspect there plenty of opportunity to further study Sucralose than has already been performed. (dossy.org)
  • In the lysosomes, the "non-canonical" pathway of LKB1-mediated AMPK activation is carried out through dissociation of fructose 1,6-bisphosphate from aldolase. (encyclopedia.pub)
  • Solomon DH, Raynal MC, Tejwani GA, Cayre YE: Activation of the fructose 1,6-bisphosphatase gene by 1,25-dihydroxyvitamin D3 during monocytic differentiation. (drugbank.com)
  • A controlled fasting study or D-fructose challenge under the supervision of a pediatric endocrinologist in the hospital setting permits recapitulation of the presentation to confirm the diagnosis. (medscape.com)
  • A growing number of studies have addressed the patterns and functions of microbial communities in the waters of different ecosystems. (frontiersin.org)
  • The results suggest that cutting back on foods and beverages containing a lot of fructose (sugar) might decrease one's risk of developing hypertension. (sciencedaily.com)
  • The newly developed "Chapon" method (MBAA 2011) demonstrates that at low pH (4.2), the strongest reducing potential results from isomaltulose followed by fructose, Vitalose®, and maltotriose. (asbcnet.org)
  • 2007). However, other studies do not support these results, probably due to the fact that prebiotics are rapidly fermented by ruminal microorganisms. (scielo.org.za)
  • All data collected from studies were converted to daily servings (S/D). Mean and standard deviations of the included results were combined by performing meta-analysis with a random effects model. (who.int)
  • It contains descriptions and evaluations of toxicological studies and epidemiological investigations and provides conclusions, where possible, on the relevance of toxicity and toxicokinetic data to public health. (cdc.gov)
  • More than 50 MSc and Ph.D. studies were completed under his supervision, and more than 10 postdoctoral fellows conducted research under his guidance. (ku.ac.ae)
  • 1995) considered that the concentration of free SO 2 remaining in the wine after the delay in racking was too low to sufficiently protect the wine. (awri.com.au)
  • Although most studies have focused on the micro-biological composition of the dental biofilm, the concentration of calcium, inorganic phosphate, fluoride, and extracellular insoluble polysaccharides is also related to its cariogenicity. (bvsalud.org)
  • Because T2DM is clinically much predominant than T1DM, in this current study, we wanted to determine whether AR also affects PPAR α in the liver of T2DM db/db mouse models. (hindawi.com)
  • Fluoroquinolone therapy and idiosyncratic acute liver injury: a population-based study. (greenmedinfo.com)
  • Methods In this cross-over study, we evaluated a population of 108 ambulatory patients affected by polygenic hypercholesterolemia of both gender, who were allocated to a tomato sauce (namely OsteoCol) 150 ml/day or a sterol-enriched yogurt (containing sterols 1.6 g/die) treatment, for 6 weeks. (researchgate.net)
  • METHODS: In this multicenter case-control study, 391 women with AUB-O and 838 controls who came from nine hospitals in Zhejiang province were recruited between April 2019 and January 2022. (bvsalud.org)
  • Despite this, a study from the Harvard School of Public Health found that people following a plant-based eating pattern had a lower occurrence of kidney stones ( 59 ). (veganhealth.org)
  • [ 1 ] In a study of phosphofructokinase-deficient mice, the authors found that because the animals' erythrocytes retained only 50% of their phosphofructokinase activity, severe hemolysis, significant decreases in 2,3-bisphosphoglycerate levels (impairing the extraction of oxygen from hemoglobin), and compensatory reticulocytosis and splenomegaly occurred. (medscape.com)
  • The study involved 4,528 US adults 18 years of age or older with no prior history of hypertension. (sciencedaily.com)
  • The genetic background of the studied cultivars/breeding lines have a higher impact on the flavor variation than the two common household storage conditions when storing ripe fruits and taking the entire post-harvest handling into account. (frontiersin.org)
  • The LSRO staff and Co-Project Officers met with the Expert Consultants between December 1993 and March 1995 to obtain background information on the NNMRRP, to review analyses of NNMRRP data prepared for this report, and to review drafts of the report. (cdc.gov)
  • The aim of this study was to compare the lipid-lowering effect of a novel functional tomato sauce with a well-known functional food with a lipid-lowering effect, i.e. a sterol-enriched yogurt. (researchgate.net)
  • [ 2 ] They reported the dramatic clinical picture of acidosis in response to D-fructose challenge. (medscape.com)
  • An immunologically similar protein to FBP was produced by Agrobacterium tumefaciens and various species of Rhizobium following growth on fructose. (microbiologyresearch.org)
  • Prof. Banat has also held several administrative positions at various universities, including Department Head, Dean of Research, Dean of Graduate Studies, and Acting Dean of Natural Resources Engineering. (ku.ac.ae)
  • This was a cross-sectional study of 142 patients identified by community screening. (scienceopen.com)
  • Findings from other studies have shown different possible mechanisms of how COVID-19 and DM aggravate the severity of each other. (jhsmr.org)
  • On a related subject, studies have shown the importance of the timing of racking post-MLF. (awri.com.au)
  • Scientific studies provide evidence that soft drinks are directly related to weight gain. (utopiasilver.com)
  • Further studies with cows earlier in lactation are necessary to evaluate the effects of AOS on milk yield and milk components. (scielo.org.za)
  • Kaur R, Dahiya L, Kumar M. Fructose-1,6-bisphosphatase inhibitors: A new valid approach for management of type 2 diabetes mellitus. (medscape.com)
  • These studies provided a number of findings that impacted his field of research. (ku.ac.ae)
  • In consideration of the reduction properties, the sugar profile of the wort should be characterized by a low content of fructose and maltotriose. (asbcnet.org)
  • This study provides a proof-of-concept for the replacement of the endogenous hexose transporters of S. cerevisiae by hexose-proton symport, and the concomitant decrease in ATP yield, to greatly improve the anaerobic yield of ethanol on sugar. (biomedcentral.com)
  • Ten studies with 67 093 children were included in this review. (who.int)
  • Seventy-two iGAS outbreaks in LTCFs were identified, from individual outbreak reports ( 1 - 14 ) or summary data identified in surveillance studies or reviews ( 6 , 13 , 15 - 20 ), or laboratory studies ( 16 ). (cdc.gov)