• Molecular
  • Walling DM, Andritsos LA, Etienne W, Payne DA, ARONSON JF, Flaitz CM, Nichols CM: Molecular markers of clonality and identity in Epstein-Barr virus-associated B-cell lymphoproliferative disease. (utmb.edu)
  • yellow fever
  • Malaria , dengue (or "breakbone fever," a severe, sometimes-deadly tropical disease transmitted by mosquitoes and accompanied by headache, rash, and severe joint pain), yellow fever , cholera , and a number of rodent-borne viruses are also appearing with increased frequency. (gcrio.org)
  • Forest
  • Semliki Forest virus (SFV) is an enveloped alphavirus that requires cellular membrane cholesterol for both membrane fusion and efficient exit of progeny virus from infected cells. (rupress.org)
  • The structure of the Semliki Forest virus revealed a structure that is similar to that of flaviviral glycoprotein E, with three structural domains in the same primary sequence arrangement. (wikipedia.org)
  • plasma membrane
  • Replication occurs within the cytoplasm, and virions mature by budding through the plasma membrane, where virus-encoded surface glycoproteins E2 and E1 are assimilated. (wikipedia.org)
  • endosome
  • SFV infects cells by cell surface receptor binding, uptake via receptor-mediated endocytosis, and low pH-triggered fusion of the virus membrane with that of the endosome. (rupress.org)
  • replication
  • These are translated directly from the full-length 42S genomic RNA and form the virus replicase responsible for RNA replication and transcription ( Takkinen, 1986 ). (pubmedcentralcanada.ca)
  • temperature
  • The rate at which the virus disseminate in the vector is limited by temperature of their environment which can be an important determinant of geographical and seasonal limits to transmission by the arthropods in the tropics. (biomedcentral.com)
  • Mutations in nsP2 that produce noncytopathic viruses or a temperature sensitive phenotypes cluster at the P2/P3 interface region. (wikipedia.org)
  • study
  • A study of this taxon suggests that this group of viruses had a marine origin - specifically the Southern Ocean - and that they have subsequently spread to both the Old and New World. (wikipedia.org)
  • spike
  • The srf-3 mutant emphasizes the relationship between the role of cholesterol in membrane fusion and virus exit, and most significantly, identifies a novel spike protein region involved in the virus cholesterol requirement. (rupress.org)
  • structure
  • A 1993 reform transformed the structure of public health care funding by shifting the burden of subsidy from providers to users. (wikipedia.org)
  • health
  • Since 1993, Grieder has been on the faculty and has conducted research at the medical school of the Uniformed Services University of the Health Sciences. (nih.gov)
  • Although this new system has widened population coverage by the social and health security system from 21% (pre-1993) to 56% in 2004 and 66% in 2005, health disparities persist, with the poor continuing to suffer relatively high mortality rates. (wikipedia.org)
  • spread
  • West Nile virus was accidentally introduced into the United States in 1999 and by 2003 had spread to almost every state with over 3,000 cases in 2006. (wikipedia.org)
  • small
  • Sequence analysis of the small RNA segment of guinea-pig passaged Pichinde virus variants. (utmb.edu)