• Peacock JM, Folsom AR, Arnett DK, Eckfeldt JH, Szklo M. Relationship of serum and dietary magnesium to incident hypertension: the Atherosclerosis Risk in Communities (ARIC) Study. (nutri-facts.org)
  • Furthermore, atherosclerosis and IA share risk factors, such as hypertension and smoking. (surgicalneurologyint.com)
  • Conversely, significant contributions from diabetes, hypertension, and lipodystrophy were not identified…… we found no evidence to suggest that the duration of HIV-1 infection, the level of prior immunodeficiency, or the degree of HIV-1 RNA replication affected the association between exposure to therapy and the risk of myocardial infarction. (natap.org)
  • Many individuals with diabetes experience impaired cardiac contractility that cannot be explained by hypertension and atherosclerosis. (diabetesjournals.org)
  • Diabetic cardiomyopathy, a diabetes-related myopathic state and a major cause of disability and morbidity for patients with diabetes, has been documented to lead to congestive heart failure even in the absence of any other risk factors such as hypertension or coronary artery disease, suggesting that diabetic cardiomyopathy is a specific cardiomyopathy associated with diabetes and independent of macrovascular complications. (diabetesjournals.org)
  • The specific objectives were to review the current evidence supporting management of ten major modifiable risk factors for prevention of stroke: hypertension, current smoking, diabetes, obesity, poor diet, physical inactivity, atrial fibrillation, excessive alcohol consumption, abnormal lipid profile and psychosocial stress/ depression. (cdc.gov)
  • 3 In this review, we discuss the biological functions of human APOE and its role in Alzheimer's disease (AD), Parkinson's disease (PD), cardiovascular diseases (CVD), multiple sclerosis (MS), type 2 diabetes mellitus (T2DM), vascular dementia (VD), and ischemic (occlusive) stroke (IS). (dovepress.com)
  • Diabetes mellitus (DM) could be classified as type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus (T2DM), gestational diabetes mellitus (GDM) and others according to etiology and pathology. (biomedcentral.com)
  • Type 2 diabetes mellitus (T2DM) and depression are significant public health and socioeconomic issues. (frontiersin.org)
  • Approximately 31% of patients with T2DM suffer from depressive symptoms, with 11.4% having major depressive disorders, which is twice as high as the prevalence of depression in patients without T2DM. (frontiersin.org)
  • Soon after the introduction of atypical antipsychotics, which antagonize serotonin receptors and dopamine D 2 receptors (D 2 R), numerous case reports appeared showing that the use of these drugs were associated with increased obesity and the development of type 2 diabetes mellitus (T2DM) ( 5 ). (frontiersin.org)
  • Conversely, the D 2 R agonist bromocriptine, which has been used for over 40 years to treat Parkinson's disease and hyperprolactinemia ( 6 ), was found to lower blood glucose levels and improve insulin sensitivity in patients with T2DM ( 7 ). (frontiersin.org)
  • The objective of this study was to assess the relationship between glycemic variability determined by a continuous glucose monitoring (CGM) system and the presence and severity of coronary artery disease (CAD) in patients with type 2 diabetes mellitus (T2DM). (biomedcentral.com)
  • In 344 T2DM patients with chest pain, coronary angiography revealed CAD (coronary stenosis ≥ 50% luminal diameter narrowing) in 252 patients and 92 patients without CAD. (biomedcentral.com)
  • The intraday glycemic variability is associated with the presence and severity of CAD in patients with T2DM. (biomedcentral.com)
  • In this study, we examined the parameters of glucose profile using continuous glucose monitoring system (CGMS) in T2DM patients with CAD, and established a correlation between glycemic variability and the severity of coronary artery disease assessed by coronary angiogram, using the Gensini score. (biomedcentral.com)
  • It is not clear whether microangiopathies are associated with subclinical atherosclerosis in type 2 diabetes mellitus (T2DM). (e-enm.org)
  • We investigated the relation of cardiac autonomic neuropathy (CAN) and other microangiopathies with carotid atherosclerosis in T2DM. (e-enm.org)
  • These results suggest that CAN is associated with carotid atherosclerosis, represented as CIMT and plaques, independent of the traditional cardiovascular risk factors in T2DM. (e-enm.org)
  • CAN or DR may be a determinant of subclinical atherosclerosis in T2DM. (e-enm.org)
  • The leading cause of death in type 2 diabetes mellitus (T2DM) is cardiovascular disease (CVD) [ 1 ]. (e-enm.org)
  • In patients with Type 2 diabetes mellitus (T2DM) parameters characterizing the degree of obesity significantly positively correlated with levels of CRP and CCL2. (medsci.org)
  • Both, obesity which is a major risk factor for the insulin resistance development and type 2 diabetes (T2DM), and the chronic hyperglycemia itself play an important role in its pathogenesis. (medsci.org)
  • Delahanty L, Simkins SW, Camelon K. Expanded role of the dietitian in the diabetes control and complications trial: implications for clinical practice. (revistasad.com)
  • Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. (revistasad.com)
  • Other goals of diabetes management are to prevent or treat the many complications that can result from the disease itself and from its treatment. (wikipedia.org)
  • Using a large, population-based administrative cohort, we found little evidence that type 2 diabetes increases the risk of depression once comorbid diseases and the burden of diabetes complications were accounted for. (cmaj.ca)
  • 9 , 10 When associated with diabetes, depression increases the risks of work loss, 11 functional disability, 11 , 12 and micro- 13 and macrovascular complications, 14 and adds to health care costs. (cmaj.ca)
  • Such knowledge could influence clinical practice by suggesting who would most effectively be screened for depression and by evaluating ways to prevent people with diabetes from becoming depressed, in order to decrease both the patients' risk of complications and the cost of the ensuing treatments. (cmaj.ca)
  • The rheumatic manifestations may result from a direct effect of the hormones, the occurrence of several autoimmune phenomena in the same person (due to genetic or environmental influences), secondary to endocrine disease complications or effects of advanced glycation end products in the case of diabetes. (springer.com)
  • Previous studies have reached conflicting conclusions on this issue, some supporting our findings and others not, but an Editorial by Peter Sklar & Henry Mazur says taken in aggregate, the weight of the evidence suggests that HIV-infected patients treated with combination antiretroviral regimens are at increased risk for the development of premature atherosclerotic complications. (natap.org)
  • Whereas coma and seizures are well-recognized neurological sequelae of hypoglycaemia, much interest is currently focused on the potential for hypoglycaemia to cause dangerous and life-threatening cardiac complications, such as arrhythmias and myocardial ischaemia, and whether recurrent severe hypoglycaemia can cause permanent cognitive impairment or promote cognitive decline and accelerate the onset of dementia in middle-aged and elderly people with diabetes mellitus. (nature.com)
  • There is convincing experimental and clinical evidence that the generation of ROS is increased in both types of diabetes and that the onset of diabetes and its complications, including diabetic cardiomyopathy, are closely associated with oxidative stress ( 7 , 8 ). (diabetesjournals.org)
  • Glucose variability is one of components of the dysglycemia in diabetes and may play an important role in development of diabetic vascular complications. (biomedcentral.com)
  • Effects of glycemic excursions on vascular complications should not be neglected in diabetes. (biomedcentral.com)
  • This association conveys a significant increase in morbidity and mortality due to atherosclerosis, microvascular complications such as retinopathy, nephropathy and premature cardiovascular disease ( 6 , 7 ). (ispub.com)
  • Cardiac autonomic neuropathy (CAN) is one of the most common complications of diabetes, and represents a significant cause of morbidity and mortality in diabetic patients. (e-enm.org)
  • The dental management of these medically compromised patients can be problematic in terms of oral complications, dental therapy, and emergency care. (medscape.com)
  • The dental clinician needs to understand the potential complications that can occur as a consequence of dental treatment of a medically compromised patient and when pretreatment or post-treatment medication or emergency care is indicated. (medscape.com)
  • As summarized elsewhere (1), the combination of a declining birth rate and an increased average life span is expected to increase the proportion of the population aged 65 years and older in the United States from 12.4% in 2000 to 19.6% in 2030. (cdc.gov)
  • Globally, the number of older adults (aged 65 years and older) is projected to increase even more dramatically - more than doubling from 420 million in 2000 to 973 million in 2030 (1). (cdc.gov)
  • Recent studies in animal models report that UA may have a causal role in the development of atherosclerosis, whereas lowering uric acid levels prevented or reversed the features of the MetS [ 23 ]. (biomedcentral.com)
  • GLA also may help to prevent inflammation-related changes implicated in the development of atherosclerosis and cancer. (lifeextension.com)
  • crease in diabetes mellitus prevalence may put more per- sons at risk for malaria infection. (cdc.gov)
  • A decade ago, type 2 dia- those receiving documented treatment with antidiabetes betes mellitus prevalence in urban Ghana was 6.3% ( 4 ). (cdc.gov)
  • The overall prevalence of diabetes using American Diabetes Association 2003 criteria was 21.4% (4.1% newly detected). (who.int)
  • The age-adjusted prevalence of MetS in the United States increased from 29.2% to 34.2% from 1999 to 2006 3 . (nature.com)
  • RA patients are more likely to have thyroid-related antibodies, and some studies indicate an increased prevalence of thyroid diseases in RA. (springer.com)
  • Pregnant SLE patients are more prone to develop thyroid diseases and pospartum thyroitidis, and in case they suffer from thyroid disease, they have an increased prevalence of preterm delivery. (springer.com)
  • The prevalence of SS among patients with autoimmune thyroiditis is increased by two- to tenfold. (springer.com)
  • As a consequence, there has also been a marked increase in the prevalence of type 2 diabetes all over the world and this chronic metabolic disease is now considered as a coronary heart disease risk equivalent. (researchgate.net)
  • Aydin S, Mete B, Yilmaz M, Yenidünya G, Zaras R, Tunckale A, Tabak F. A patient with HIV infection presenting with diffuse membranous glomerulonephritis in a country with a low HIV prevalence--remarkable remission with therapy. (florence.com.tr)
  • 13 ] also demonstrated that the prevalence of the MetS increased according to serum UA levels only in women and in men without the Mets, suggesting that UA levels were an independent risk factor of carotid atherosclerosis. (biomedcentral.com)
  • The study was meant to estimate the prevalence of metabolic syndrome in patients with breast cancer and to establish its role as an independent risk factor on occurrence of breast cancer. (ijmpo.org)
  • Metabolic syndrome prevalence was found in 40.0% of breast cancer patients, and 18.0% of those in control group ( P = 0.02). (ijmpo.org)
  • Prevalence, characteristics and clinical diagnosis of maturity onset diabetes of the young due to mutations in HNF1A, HNF4A, and glucokinase: Results from the SEARCH for Diabetes in Youth. (medarhive.ru)
  • Long term diabetes and poor glycemic control are the most important risk factors for DN development ( DCCT Research Group, 1993 ). (scialert.net)
  • Although the pathophysiological mechanism of this increased mortality is unclear, it may be related to silent myocardial ischemia and subclinical coronary atherosclerosis [ 9 , 10 ]. (e-enm.org)
  • Carotid atherosclerosis as estimated by carotid intima-media thickness (CIMT) and plaques is considered to reflect an early stage of atherosclerotic disease and is therefore used as a surrogate marker for diabetic macroangiopathies [ 6 - 8 ]. (e-enm.org)
  • So far, studies on the relationship between diabetic microangiopathies and carotid atherosclerosis have yielded inconsistent results. (e-enm.org)
  • However, studies on the relationship between CAN and carotid atherosclerosis are few [ 11 , 12 ]. (e-enm.org)
  • Aassociations between carotid atherosclerosis and both urine albumin excretion (UAE) and glomerular filtration rate (GFR) in diabetic patients have been investigated, but these studies showed only inconsistent results [ 5 , 13 , 14 ]. (e-enm.org)
  • 12 ] showed in both males and females without the MetS that hyperuricemia is an independent risk factor for the incidence of carotid atherosclerosis imaged by ultrasound. (biomedcentral.com)
  • Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. (revistasad.com)
  • The presence of atherosclerotic plaque in some IAs and similar histological and biochemical features of aneurysms and atherosclerotic lesions suggest that atherosclerosis may be a mechanism in the pathogenesis of IAs. (surgicalneurologyint.com)
  • We designed the PRIZE study to evaluate the effects of febuxostat on a surrogate marker of cardiovascular disease risk, ultrasonography-based intima-media thickness of the carotid artery in patients with hyperuricemia. (biomedcentral.com)
  • Individuals were invited by letter to attend for assessment of their medical history, risk factor status, cognitive function and psychological profile, morbidity, and carotid intima-media thickness and plaque count as indices of atherosclerosis. (biomedcentral.com)
  • Obesity can be viewed as a state of long-term lipid disequilibrium that is marked by massive adipocyte hypertrophy and is a major risk factor for developing insulin resistance and type 2 diabetes. (jci.org)
  • However, even in the absence of the hyperglycaemic state which characterizes type 2 diabetic patients, non diabetic individuals with a specific form of obesity, named abdominal obesity, often show clustering metabolic abnormalities which include high triglyceride levels, increased apolipoprotein B, small dense low density lipoproteins and decreased high density lipoproteins-cholesterol levels, a hyperinsulinemic-insulin resistant state, alterations in coagulation factors as well as an inflammatory profile. (researchgate.net)
  • Post-mortem analyses of coronary arteries have indicated that obesity (associated with a high accumulation of abdominal fat measured at autopsy) was predictive of earlier and greater extent of large vessels atherosclerosis as well as increase of coronary fatty streaks. (researchgate.net)
  • Metabolic syndrome linked to abdominal obesity is also predictive of recurrent coronary events both in post-myocardial infarction patients and among coronary artery disease men who underwent a revascularization procedures. (researchgate.net)
  • Clinical and investigational evidence suggests that the increased breast cancer risk associated with greater abdominal visceral obesity may be related to anomalous insulin signaling through the insulin receptor substrate 1 pathway, leading to insulin resistance, hyperinsulinemia, and increased concentrations of endogenous estrogen and androgen. (ijmpo.org)
  • Disturbed lipid and carbohydrate metabolism are manifested by enhanced inflammation and endothelial dysfunction in patients with simply obesity. (medsci.org)
  • In patients with obesity and type 2 diabetes, altered serum concentrations of Il-10 seems to be dependent on the degree of insulin resistance and proinflammatory status. (medsci.org)
  • This review will summarize the updated research progress on APOE functions and its role in Alzheimer's disease, Parkinson's disease, cardiovascular diseases, multiple sclerosis, type 2 diabetes mellitus, Type III hyperlipoproteinemia, vascular dementia, and ischemic stroke. (dovepress.com)
  • Excess oxidative stress induces endothelial dysfunction and inflammatory reactions in vascular systems, leading to atherosclerosis. (biomedcentral.com)
  • It differs between organs and potentially also between different vascular beds within the same organ [ 1 ]. (hindawi.com)
  • Currently increasing importance is attributed to the inflammatory process as a crucial factor responsible for the progressive damage to vascular walls and progression of atherosclerosis in obese people. (medsci.org)
  • Cavalot F, Pagliarino A, Valle M. Postprandial blood glucose predicts cardiovascular events and all-cause mortality in type 2 diabetes in a 14-year follow up: lessons from the San Luigi Gonzaga diabetes study. (revistasad.com)
  • Over the last 40 years many studies have demonstrated a relation between survival and forced expiratory volume in 1 s (FEV 1 ) in general population samples, 1 2 and have shown that low FEV 1 is associated with high mortality from cardiovascular causes. (bmj.com)
  • 5 FEV 1 , however, does not define COPD and an association has also been identified between mortality and vital capacity. (bmj.com)
  • BACKGROUND: Plant-based dietary patterns are gaining more attention due to their potential in reducing the risk of developing major chronic diseases, including type 2 diabetes (T2D), cardiovascular disease (CVD), cancer, and mortality, while an up-to-date comprehensive quantitative review is lacking. (bvsalud.org)
  • the results could mortality, accounting for 63% and 9%, respectively, of 57 million inform policymakers of which risk factors need to be prioritized in deaths in 2008 [1]. (who.int)
  • The objective of our study was to evaluate whether people with diabetes have a greater incidence of depression than those without diabetes. (cmaj.ca)
  • The incidence of new-onset depression was similar in both groups (6.5 v. 6.6 per 1000 person-years among people with and without diabetes, respectively). (cmaj.ca)
  • Little information is currently available on the obverse of that temporal chain: the incidence of depression among people who have diabetes. (cmaj.ca)
  • We therefore conducted a population-based retrospective cohort study to evaluate the incidence of new-onset depression among people with diabetes, compared with those who do not have diabetes. (cmaj.ca)
  • The incidence of childhood onset type 1 diabetes is increasing in many countries in the world, at least in the under 15-year-old age group. (bvsalud.org)
  • There are strong indications of geographic differences in trends but the overall annual increase is estimated to be around 3%.Two international collaborative projects, the Diabetes Mondiale study (DiaMond)1 and the Europe and Diabetes study (EURODIAB) 2 have been instrumental in monitoring trends in incidence. (bvsalud.org)
  • Of the estimated 480,000 children with type 1 DM, 24% come from the South-East Asian Region, but the European Region, where the most reliable and up-to-date estimates of incidence are available, comes a close second (23%) 3 .The incidence rate of type 1 DM in India is 4.2/100,000 population per year. (bvsalud.org)
  • Diabetic patients with CAD were older, and more were male and cigarette smokers compared with the controls. (biomedcentral.com)
  • However, there have been no sufficient studies presented so far that specifically evaluated the relationship between glycemic variability and coronary artery disease in diabetic patients. (biomedcentral.com)
  • Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients by transient intensive insulin treatment. (florence.com.tr)
  • Although in all diabetic patients, GFR is initially normal or mildly elevated with no histological alterations, it progresses to produce thick glomerular basement membrane and expand to mesangial, followed by high glomerular capillary pressure and microalbuminuria. (scialert.net)
  • However, there is only limited evidence on the clinical implications of xanthine oxidase inhibitors on atherosclerotic cardiovascular disease in patients with hyperuricemia. (biomedcentral.com)
  • ABSTRACT This study aimed to develop a simple risk score to identify individuals at high risk for undiagnosed diabetes in the Kuwaiti adult population and to assess the performance of previously published diabetes risk scores. (who.int)
  • ABSTRACT Associations of oral diseases with noncommunicable diseases such as diabetes, cardiovascular diseases, chronic respiratory diseases, osteoporosis and chronic renal failure are widely reported in the literature from developed countries. (who.int)
  • Ferrarini E. Physiology of glucose homeostasis and insulin therapy in type 1 and type 2 diabetes. (revistasad.com)
  • Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes. (revistasad.com)
  • The term diabetes includes several different metabolic disorders that all, if left untreated, result in abnormally high concentrations of a sugar called glucose in the blood. (wikipedia.org)
  • The treatment goals are related to effective control of blood glucose, blood pressure and lipids, to minimize the risk of long-term consequences associated with diabetes. (wikipedia.org)
  • 13 , 15 Diabetes with comorbid depression is also linked with poorer adherence to medications and self-care activities such as self-monitoring of blood glucose levels and adhering to a proper diet and exercise program. (cmaj.ca)
  • Prevention of hypoglycaemia is an important part of diabetes mellitus management and strategies include patient education, glucose monitoring, appropriate adjustment of diet and medications in relation to everyday circumstances including physical exercise, and the application of new technologies such as real-time continuous glucose monitoring, modified insulin pumps and the artificial pancreas. (nature.com)
  • Traditionally this has involved studying both central and peripheral molecules involved in hunger and satiety, such as leptin, orexin (also known as hypocretin), insulin, alpha-melanocyte-stimulating hormone (α-MSH), glucagon-like peptide -1 (GLP-1), amylin, glucose-dependent insulinotropic polypeptide (GIP, also known as a gastric inhibitory polypeptide), adiponectin and cholecystokinin (CCK). (frontiersin.org)
  • The patients had their saliva collected and evaluated for glucose, cholesterol, total protein and albumin. (bvsalud.org)
  • Therefore, in order to assess the risk of diabetes, it may be necessary to evaluate not only the mean level of glycemic control, but also the extent of glucose excursions. (biomedcentral.com)
  • Although all diabetic cells are exposed to elevated levels of plasma glucose, hyperglycemic damage is limited to those cell types that are unable to down regulate glucose transport into the cell (e.g., endothelial cells), leading to intra-cellular hyperglycemia ( Brownlee, 2001 ). (scialert.net)
  • We have studied the relationship between clinical and biochemical parameters and C-peptide and anti-inflammatory IL-10, as well as selected markers of inflammation and endothelial dysfunction such as: CCL2, CRP, sICAM-1, sVCAM-1 and E-selectin in obese women with various degree of glucose metabolism disturbance. (medsci.org)
  • Obese patients were spited in subgroups based on the degree of glucose metabolism disorder. (medsci.org)
  • Clinical Diabetes, 2004:22:169-72. (revistasad.com)
  • They are suggested in clinical practice guidelines released by various national and international diabetes agencies. (wikipedia.org)
  • The purpose of this study was to evaluate clinical and morphological factors affecting atherosclerosis of an aneurysm and identify the parameters that predict aneurysm stabilization. (surgicalneurologyint.com)
  • To investigate the relation between echocardiographic parameters and 24-hour ambulatory blood pressure monitoring (ABPM) in normoalbuminuric pre-hypertensive adults with type 1 diabetes mellitus (T1DM) without clinical evidence of nephropathy or cardiovascular autonomic neuropathy. (ispub.com)
  • There were no differences between the dipper and the nondipper T1DM pre-hypertensive patients with respect to age, gender, body mass index, clinical and ABPM for average day-time systolic and diastolic blood pressure levels. (ispub.com)
  • After written consent, these patients were divided into two groups according to the clinical parameters as healthy and disease (chronic periodontitis) groups. (bvsalud.org)
  • Several single gene disorders share clinical and radiologic characteristics with multiple sclerosis and have the potential to be overlooked in the differential diagnostic evaluation of both adult and paediatric patients with multiple sclerosis. (medscape.com)
  • Here we review single gene disorders that have the potential to mimic multiple sclerosis, provide an overview of clinical and investigational characteristics of each disorder, and present guidelines for when clinicians should suspect an underlying heritable disorder that requires diagnostic confirmation in a patient with a definite or probable diagnosis of multiple sclerosis. (medscape.com)
  • Patients with multiple sclerosis are classified according to their clinical phenotype, with ~85% following a relapsing-remitting course (relapsing-remitting multiple sclerosis) characterized by recurrent, acute neurological deficits punctuating periods of latency or remission (Lublin and Reingold, 1996). (medscape.com)
  • In the absence of pathognomonic clinical findings or a definitive laboratory test, the diagnosis of multiple sclerosis remains challenging in many patients, and diagnostic criteria emphasize the caveat of 'no better explanation' for a patient's clinical presentation and MRI findings. (medscape.com)
  • Vitamin E supplementation improves endothelial function in type I diabetes mellitus: A randomized placebo-controlled study. (scialert.net)
  • Oral magnesium therapy improves endothelial function in patients with coronary artery disease. (nutri-facts.org)
  • 41 ] Rupture of an IA occurs in relatively young people and has a high fatality and morbidity rate, but the majority of patients with incidentally detected IA have a benign course. (surgicalneurologyint.com)
  • Diabetes is a methabolic disease characterized by hyperglycemia, with high morbidity and mortility worldwide. (scialert.net)
  • Hypothyroidism contributes to the increased risk for cardiovascular diseases and metabolic syndrome in RA patients and may be correlated with RA disease activity and response to treatment. (springer.com)
  • It has been over 30 years since Reaven first described metabolic syndrome, which commonly affects overweight individuals ( 1 ). (frontiersin.org)
  • Metabolic syndrome is more prevalent in breast cancer patients and is an independent risk factor for breast cancer. (ijmpo.org)
  • May also increase vagal cardiac input in POTS patients. (medscape.com)
  • Cardiac transplant is a widely accepted therapy for select patients with end stage cardiovascular disease. (lidsen.com)
  • Maturity-Onset Diabetes of the Young: What Do Clinicians Need to Know? (medarhive.ru)
  • Maturity-onset diabetes of the young (MODY): How many cases are we missing? (medarhive.ru)
  • Natural antioxidants for prevention of atherosclerosis. (scialert.net)
  • Conclusively, the IRS-1 gene polymorphism Gly972Arg should be considered as an important factor in the prevention and treatment of ischemic stroke. (biomedcentral.com)
  • A case-control study of 1,466 urban adults in Ghana tory and socioeconomic background, underwent physical found that patients with type 2 diabetes mellitus had a 46% examination, and provided venous blood and urine samples increased risk for infection with Plasmodium falciparum . (cdc.gov)
  • Logistic re- adults with and without type 2 diabetes mellitus residing gression produced adjusted odds ratios (aORs), and 95% in Kumasi, Ghana. (cdc.gov)
  • Postchallenge hyperglucemia in a national sample of U.S. adults with type 2 diabetes. (revistasad.com)
  • Increasing vitamin K intake has been shown to increase carboxylation of extra-hepatic VKD proteins in apparently healthy adults, as well as those with osteoporosis and atherosclerosis. (vitamindwiki.com)
  • According to the most recent national survey data, over half of the adults in China are either overweight (34.3%) or obese (16.4%) [ 1 ]. (biomedcentral.com)
  • Fructosamine reflects the glycemic control over the previous 1-2 weeks and has been correlated positively with serum albumin and serum total protein5. (bvsalud.org)
  • ISIS-4: a randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58,050 patients with suspected acute myocardial infarction. (nutri-facts.org)
  • 4-7 In the setting of coronary artery disease, several studies have shown the efficacy of magnesium infusion in patients with acute myocardial infarction, 4 vasospastic angina, 5 and unstable angina. (bmj.com)
  • No patients had a history of prior myocardial infarction, heart failure, or other serious diseases. (bmj.com)
  • Atherosclerosis is now understood to be an inflammatory disorder with key components of the innate immune system being intimately involved in the initiation and progression of plaques on the artery wall, and in triggering an acute coronary event such as myocardial infarction[ 14 ]. (biomedcentral.com)
  • Type 2 diabetes mellitus increases susceptibil- ceiving documented antihypertension treatment or having ity to common infections ( 5 ). (cdc.gov)
  • Although diabetes mellitus has a strong association with the presence of depression, it is unclear whether diabetes itself increases the risk of developing depression. (cmaj.ca)
  • Damage can be attributed to ROS production, and diabetes increases ROS production via angiotensin II and flavoprotein enzyme‐dependent pathways. (diabetesjournals.org)
  • Rheumatoid arthritis is the most common coexisting autoimmune disorder in patients with Grave's disease and Hashimoto thyroiditis. (springer.com)
  • Heart disease, diabetes, some cancers, rheumatoid arthritis and mental illness are examples of the burden of ill-health that is carried disproportionately by deprived communities[ 1 ]. (biomedcentral.com)
  • Of the 1,466 study participants, 675 (46%) had type agricultural areas ( 6 ). (cdc.gov)
  • UK Prospective Diabetes Study Group. (revistasad.com)
  • We recently conducted a large, population-based, nested case- control study 21 that suggested an association between a history of depression and the onset of type 2 diabetes, but this increased risk was limited to people no older than 50 years. (cmaj.ca)
  • Methods: 32 children with type 1 diabetes mellitus formed the study group (DC) and 32 non-diabetic children formed the control group (ND). (bvsalud.org)
  • The cholesterol-fed LDLR-/- mice offer a new model for the study of environmental and genetic factors that modify the processes of atherosclerosis and xanthomatosis. (jci.org)
  • A multi-center, open label, crossover designed prospective study evaluating the effects of lipid lowering treatment on steroid synthesis in patients with Type 2 diabetes (MODEST STUDY). (florence.com.tr)
  • This study aims to identify insulin receptor substrate 1 (IRS-1) gene polymorphism Gly972Arg as the risk factor for ischemic stroke among Indonesian subjects. (biomedcentral.com)
  • The case-control study was conducted by matching the gender and race on 85 cases of patients with ischemic stroke and 86 healthy non-stroke control subjects. (biomedcentral.com)
  • The current study addresses the question on whether IRS-1 gene polymorphism Gly972Arg acts as the risk factor for ischemic stroke among Indonesian subjects. (biomedcentral.com)
  • The inclusion criteria for ischemic stroke patients was acute ischemic stroke cases with onset of stroke within 7 days, aged 35-75 year old, Malay race, and treated in the Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia, and provided written consent to be enrolled in the study. (biomedcentral.com)
  • Written informed consent was obtained from all patients before the study. (bmj.com)
  • Anderson showed an association between the FEV 1 /FVC ratio and survival in New Guinea, 6 but neither Friedman 3 in his original study nor Lange in the Copenhagen Heart Study 4 showed a convincing association with cardiovascular end points. (bmj.com)
  • PRIZE will be the first study to provide important data on the effects of febuxostat on atherosclerosis in patients with asymptomatic hyperuricemia. (biomedcentral.com)
  • Patients affected by histologically confirmed breast cancer either pre- or post-menopausal were recruited for the study. (ijmpo.org)
  • The purpose of the present study was to examine the psychosocial, behavioural and biological determinants of ill health within population groups in Glasgow that differed in socioeconomic status and in their propensity to develop chronic disease especially coronary heart disease and Type 2 diabetes mellitus. (biomedcentral.com)
  • Of the total of 230 outpatients approached to participate in the study, 100 eligible patients were selected as per the selection criteria. (bvsalud.org)
  • Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice. (jci.org)
  • The results suggest the probable active participation of higher concentrations of C-peptide in the intensification of inflammatory and atherogenic processes in obese patients with type 2 diabetes. (medsci.org)
  • METHODS: The nationwide Japanese KD survey contained substantial information on KD patients with CALs detected at admission and who received standard IVIG treatment within 10 days of disease onset. (cdc.gov)
  • Approximately 15% of patients follow a primary progressive or progressive relapsing course from disease onset, usually characterized by symptoms of progressive myelopathy (gait instability, spasticity, bladder symptoms) and cognitive impairment. (medscape.com)
  • Assessing the metabolic control of the patient has traditionally been done through testing of glycosylated hemoglobin, fructosamine, and glycoalbumin along with other criteria such as Body Mass Index, microalbuminuria and dyslipidemia 6-7 . (bvsalud.org)
  • Gluten seems a potentially important determinant in type 1 diabetes (T1D) and type 2 diabetes (T2D). (mdpi.com)
  • Chronic overexpression of MT or acute in vitro treatment with the flavoprotein inhibitor diphenyleneiodonium or the angiotensin II type I receptor antagonist losartan eliminated excess ROS production in diabetic cardiomyocytes. (diabetesjournals.org)
  • Evaluation of the left ventricular systolic and diastolic functions by echocardiography in patients with acute leukemia. (florence.com.tr)
  • Both MK-4 and the long-chain MKs are present in the diet in minute (mcg) amounts (see Table 1: Micrograms of Vitamin K Present in Foods). (vitamindwiki.com)
  • In wild type littermates fed the same diet, the total plasma cholesterol remained (jci.org)
  • No such changes were seen in the LDLR-/- mice on a normal chow diet, nor in wild type mice that were fed either a chow diet or the high-fat diet. (jci.org)
  • High iron intake in the diet might increase the risk of heart disease in females with type 2 diabetes . (webmd.com)
  • Health-conscious individuals try to reduce this type of fat in their diet. (lifeextension.com)
  • In most studies, thyroid diseases (mainly hypothyroidism) are more common in SLE patients. (springer.com)
  • Oral diseases are included among the on NCD in this Region and to stress the World Health Organization (WHO) defini- importance of oral health issues in medicine tion of chronic diseases [ 1 ], and the im- in relation to the risk of NCD. (who.int)
  • Human magnesium deficiency (including conditions which show few overt symptoms) is relatively common, with only 32% of the United States meeting the RDA-DRI,[1] and has been implicated in the development of a number of human illnesses such as asthma, osteoporosis, and ADHD. (spagyricarts.com)
  • Recognition of a single-gene disorder as causal for a patient's 'multiple sclerosis-like' phenotype is critically important for accurate direction of patient management, and evokes broader genetic counselling implications for affected families. (medscape.com)
  • Early, accurate diagnosis is critical to effective patient management and counselling, but assignment of an incorrect diagnosis of multiple sclerosis remains a frequent concern. (medscape.com)
  • 80% of patients with multiple sclerosis and may be considered as supporting evidence, but are neither completely sensitive nor specific for multiple sclerosis. (medscape.com)
  • Diabetes mellitus type 1 results when the pancreas no longer produces significant amounts of the hormone insulin, usually owing to the autoimmune destruction of the insulin-producing beta cells of the pancreas. (wikipedia.org)
  • 15,16 The results can be a profound reduction in the impact of inflammation on cardiovascular disease, lung function, autoimmune conditions, and metabolic abnormalities including diabetes. (lifeextension.com)
  • Colclough H, Percy J, Benford M. Levels of FPG and HbA1c control and the relationship to BMI in T2D patients treated with basal insulin and OAD therapy, presented at the 2012 72nd Scientific Session at the American Diabetes Association Meeting , 8-12 June, Philadelfia, USA. (revistasad.com)
  • Heart transplant remains the gold standard therapy for patients with end stage heart disease and offers improved survival and quality of life. (lidsen.com)
  • Moreover, phosphodiesterase 4D (PDE4D) [ 13 ], and 5-lipoxygenase gene activating protein (ALOX5AP) [ 14 ], were shown to be significantly related with ischemic stroke due to progressive changes in the walls of blood vessels resulting in the increased atherosclerosis process. (biomedcentral.com)
  • In older patients (≥65 years of age), multivariate logistic regression revealed that only diabetes was associated with stabilized aneurysms ( P = 0.027). (surgicalneurologyint.com)
  • In multivariable adjusted logistic regression analysis, the patients who presented with CAN showed an odds ratio [OR] of 8.6 (95% confidence interval [CI], 1.6 to 44.8) for CIMT thickening and an OR of 2.9 (95% CI, 1.1 to 7.5) for carotid plaques. (e-enm.org)
  • As of November 1, 2011 the world's population is estimated to be 7 billion. (medscape.com)
  • [ 2 ] In healthy women, 80% of testosterone is bound to sex hormone binding globulin (SHBG), 19% is bound to albumin, and 1% circulates freely in the blood stream. (medscape.com)
  • This data file comprises the data collected by the NHAMCS in 1993. (cdc.gov)
  • These results provide useful information in determining treatment and follow-up strategies, especially in older patients. (surgicalneurologyint.com)
  • As the blood vessels are blocked in the excess coagulation of the plaques results in choking and heart failure in the time of birth (Figure 1) . (omicsonline.org)
  • Results Survival was strongly associated with forced vital capacity (FVC) after adjustment for FEV 1 , but not the other way round. (bmj.com)
  • We identified 31 635 people with diabetes and 57 141 without. (cmaj.ca)
  • Several investigations 5 - 8 have documented that people with diabetes experience depression from 1.3 to 3 times as often as those without the disorder. (cmaj.ca)
  • Taking an extract of black and green tea by mouth doesn't improve blood sugar levels in people with diabetes. (medlineplus.gov)
  • Plasmodium falci- tive of symptoms, malaria parasites were counted per 500 parum malaria alone causes an estimated 1 million deaths leukocytes on Giemsa-stained thick blood fi lms. (cdc.gov)
  • The proposed score had 87% sensitivity and 64% specificity in predicting undetected diabetes using only 4 questions (age, waist circumference, use of blood pressure medication and diabetes in a sibling). (who.int)
  • Adult patients who were diagnosed as T1DM and pre-hypertensive were categorized as dippers and non-dippers on the basis of 24-hour ambulatory blood pressure measurement and their echocardiographic parameters were compared. (ispub.com)
  • The advent of 24-hour ambulatory blood pressure (ABPM) monitoring has made it possible to record blood pressure (BP) during daily activities and during sleep ( 1 ). (ispub.com)
  • Elevated blood pressure levels are more frequently observed in patients with Type 1 diabetes mellitus (T1DM) than in the general population ( 5 , 6 , 7 ). (ispub.com)
  • Cerebral endothelium is probably one of the most specific types since it is the crucial element of the well-known blood-brain barrier. (hindawi.com)
  • To compare and evaluate the relationship between anemia and periodontitis by estimation of peripheral blood between healthy patients and chronic periodontitis patients. (bvsalud.org)