• In addition there are other lipids and proteins in the membrane, the latter typically in the form of isolated rafts. (wikipedia.org)
  • Fully embedded proteins are called integral membrane proteins because they traverse the entire thickness of the lipid bilayer. (wikipedia.org)
  • Proteins that are only partially embedded in the bilayer are called peripheral membrane proteins. (wikipedia.org)
  • The membrane skeleton is a network of proteins below the bilayer that links with the proteins in the lipid membrane. (wikipedia.org)
  • Assume that each proteins in the membrane skeleton have similar length which is much smaller than the whole size of the cell membrane, and that the membrane is locally 2-dimensional uniform and homogenous. (wikipedia.org)
  • In Escherichia coli , ribosomes must interact with translocons on the membrane for the proper integration of newly synthesized membrane proteins, cotranslationally. (rupress.org)
  • Recently, it has been recognized that membrane-bound ribosomes are crucial for biogenesis of integral membrane proteins in E. coli , thus renewing interest in ribosome targeting to and association with the membrane in this organism. (rupress.org)
  • Evidence is accumulating that small G proteins are involved in the regulation of cell growth and differentiation. (nii.ac.jp)
  • High levels of intracellular calcium ion activate proteolytic enzymes (known as calpains) that break down many cell proteins, particularly those in the cytoskeleton of neurons (spectrin, neurofilament and microtubule-associated protein). (benbest.com)
  • Lipids and proteins are attacked and oxidized, resulting in loss of chlorophyll and carotenoids and in leaky membranes which allow cells and cell organelles to dry and disintegrate rapidly. (weedscience.org)
  • In cells lacking expression of Ca 2+ -mobilizing G proteins, coexpression of human GPR40 and Gα q allowed medium- and long-chain fatty acids to elevate intracellular [Ca 2+ ]. (aspetjournals.org)
  • Fibrosis is characterised by an excessive production of extracellular matrix components, and cells in the tissue are constantly interacting with these extracellular matrix proteins. (bmj.com)
  • 1995). These 3 proteins have been shown to be present on the plasma membrane of many cell types including vascular endothelium (Stitt et al. (reactome.org)
  • Many existing tissue-engineering approaches focus on delivery of selected proteins (growth factors, transcription factors etc.) or nucleic acids to host or implanted stem cells to achieve lineage specific differentiation. (frontiersin.org)
  • To reduce the risk of analyzing cell line- pathway can be divided into distinct stages based on the specific features, we used several representative cell lines for recombination status of the Ig genes and on the expression each of four major stages in B cell development: pro-B, pre-B, pattern of surface markers and the presence of intracellular proteins [1- 6]. (lu.se)
  • In Caenorhabditis elegans motor neurons, dense core vesicles dock at the plasma membrane but are excluded from active zones at synapses. (rupress.org)
  • Neurons can release small molecule neurotransmitters very rapidly in part because synaptic vesicles are docked to the membrane at active zones. (rupress.org)
  • Although spontaneous changes of [Ca 2+ ] i have been examined in immature cortical neurons, the calcium dynamics of cortical precursor cells have received less attention. (jneurosci.org)
  • Immunohistochemical staining confirmed that these events occurred primarily in precursor cells rather than in postmitotic neurons. (jneurosci.org)
  • Most of the metabolic energy of neurons is expended on maintaining ion gradients across the cell membrane. (benbest.com)
  • Measuring the firing rate of high-resistance neurons with cell-attached recording. (sppin.fr)
  • Axonal speeding: shaping synaptic potentials in small neurons by the axonal membrane compartment. (sppin.fr)
  • At the early 1980s, the ion channels in cardiac cells were not as clear as neurons , especially the channels concerned with calcium ions including those in the sarcoplasmic reticulum. (scholarpedia.org)
  • Countering NADH production, calcium action on the mitochondrial permeability transition pores increases inner membrane permeability thereby reducing proton potential, causing the matrix to swell and ultimately releasing cytochrome c (an initiator of apoptosis). (benbest.com)
  • The calculated effects of an abrupt increase in the permeability coefficients of K + , Na + , Cl − channels, or the NC cotransport rate coefficient on cell K + , Na + , and Cl − content and concentrations, water-volume (V/A) and MP (U). The data were calculated by using the software BEZ01B. (researchgate.net)
  • 2016. A set of examples is presented in Figure 1 to show how changes in a single channel or transporter species (one permeability coefficient or rate constant) can alter the intracellular concentrations of all major ions, cell water content and the MP. (researchgate.net)
  • The conductance was similar in the two regions, although permeability in the two regions of the membrane long after the pulse treatment appeared quite different. (elsevierpure.com)
  • In this model, the cell membrane surface is modeled as a two-dimensional fluid-like lipid bilayer where the lipid molecules can move freely. (wikipedia.org)
  • The simplest component of a membrane is the lipid bilayer which has a thickness that is much smaller than the length scale of the cell. (wikipedia.org)
  • A cell membrane is simplified as lipid bilayer plus membrane skeleton. (wikipedia.org)
  • The availability of cholesterol constitutes the rate-limiting step of steroidogenesis and is regulated by STARD1 which transfers cholesterol from the outer to the inner mitochondrial membrane 5 . (nature.com)
  • In the last decades, the Helfrich model has been extensively used in computer simulations of vesicles, red blood cells and related systems. (wikipedia.org)
  • Docking to the plasma membrane prepares vesicles for rapid release. (rupress.org)
  • Dense core vesicles are usually found in the cytoplasm and these cytoplasmic vesicles must presumably translocate to the plasma membrane before release ( Zupanc, 1996 ). (rupress.org)
  • Sackmann E (1995) Physical basis of self-organization and function of membranes: physics of vesicles. (aimspress.com)
  • Additionally, new lipid structures also appear inside the host cell: the parasite is surrounded by a parasitophorous vacuole membrane [ 24 ] and new parasite induced membranous structures (Maurer's clefts and transport vesicles) emerge, which play an important role in trafficking of parasite virulence factors to the surface of infected red blood cell (iRBC) membranes. (biomedcentral.com)
  • During abruptions, decidual cell and neutrophil-derived proteases effectively degrade the decidual and fetal membrane extracellular matrix to promote preterm premature rupture of the membranes and preterm delivery (PTD). (scirp.org)
  • The aim of this study was to investigate whether mast cells accumulate in these tissues and whether their localisation is associated with extracellular matrix components. (bmj.com)
  • Many of these studies highlighted the significant effects of liquid junction potentials on membrane potential measurement, which are generally increased in patch-clamp situations. (edu.au)
  • This resulted in analyses to evaluate and correct errors arising from such liquid junction potentials in a range of different situations and led him to develop a C/C++ DOS-based Windows software program, JPCalc , to calculate and apply appropriate corrections to experimental membrane potential measurements. (edu.au)
  • Dr. Luo made a decision to skip the debate issue but, instead, put them all into the cell model to see how action potentials look like by using those published experimental data for calcium ion channels, especially sodium-calcium exchangers. (scholarpedia.org)
  • Modulation of intracellular free calcium concentration ([Ca 2+ ] i ) may be part of the signaling pathway by which both local environmental factors and cell autonomous developmental programs influence corticogenesis. (jneurosci.org)
  • The accumulation of FtsY-ribosome complexes induces the formation of intracellular membranes needed for their quantitative accommodation. (rupress.org)
  • Our results with E. coli , in conjunction with recent observations made with the yeast Saccharomyces cerevisiae , raise the possibility that the SRP receptor-mediated formation of intracellular membrane networks is governed by evolutionarily conserved principles. (rupress.org)
  • found that the kinetics of the disturbance of cell ion and water balance caused by blocking the Na +/ K + pump when the intracellular K + /Na + ratio is highly changed and even reversed can be predicted sufficiently well by calculation with the invariant parameters ( Vereninov et al. (researchgate.net)
  • previous paper presented the typical dependences for the cells with high MP and high intracellular K/Na ratio, for the cells with low MP and high K/Na ratio (high potassium erythrocytes) and for the low-MP and low-K/Na-ratio cells (low-potassium erythrocytes of some carnivores and ruminants) ( Vereninov et al. (researchgate.net)
  • To this end, MCF-7 cells were exposed to TAC and Orai1 protein abundance at the cell surface was determined by confocal microscopy and flow cytometry as well as intracellular Ca 2+ release and SOCE were quantified utilizing Fura-2 fluorescence. (biomedcentral.com)
  • To this end, MCF- cells were treated with testosterone-albumin conjugates (TAC, 100 nM), which selectively activate mAR without activating intracellular androgen receptors (iAR). (biomedcentral.com)
  • To make a model cell alive, it needs the ion pumps to maintain the intracellular ion balance, i.e., the ions must return back after the firing of an action potential. (scholarpedia.org)
  • For heart muscle contraction, a single heart cell is stimulated to raise the intracellular potential from the resting -80 mV to about +40 mV by flowing positive sodium ions due to the opening of the sodium channel. (scholarpedia.org)
  • We have found that the levels of smg p21 mRNA increase in hematopoietic leukemiae cells after their differentiation into hematopoietic cells. (nii.ac.jp)
  • We have also found that smg p25A is mainly detected inneural tissues by use of its specific monoclonal antibody, and that the levels of smg p25A mRNA increase in PC12 cells after their differentiation into neuron-like cells. (nii.ac.jp)
  • In three-dimensional reconstituted basement membrane culture, they undergo a well-defined program of proliferation, differentiation, and growth arrest, forming acinar structures that recapitulate many aspects of mammary architecture in vivo . (biomedcentral.com)
  • Here we report on the growth and differentiation properties of these three matched cell lines in three-dimensional basement membrane culture. (biomedcentral.com)
  • Subsequent differentiation allows for rear- analysis of a set of mouse B lineage cell lines rep- rangements of the Ig light-chain (IgL) genes that replace the resenting defined stages of B cell development us- surrogate light-chain genes on the surface of the B cell [8]. (lu.se)
  • Cellular morphology, time-lapse imaging, and nuclear staining demonstrated that this activity occurred in mitotically active cells. (jneurosci.org)
  • Resisting cell death', 'genome instability and mutation' and 'deregulating cellular energetics' refine breast cancer classification with their predictive values. (jcancer.org)
  • 2015) Nanoparticle colloidal stability in cell culture media and impact on cellular interactions. (aimspress.com)
  • The biconcave disk shaped human cells are devoid of a nucleus and of most cellular organelles. (biomedcentral.com)
  • check the tag ADOLESCENCE HN - 2008 BX - Nutrition in Adolescence FX - Adolescent Nutrition Physiology MH - Peritoneal Stomata UI - D054048 MN - A01.047.025.600.700 MN - A10.810 MS - Natural openings in the subdiaphragmatic lymphatic plexus in the PERITONEUM, delimited by adjacent mesothelial cells. (bvsalud.org)
  • Postsynaptic membranes contain several types of glutamate receptors, notably NMDA & AMPA receptors, which allow calcium ion entry. (benbest.com)
  • Postsynaptic membranes contain two voltage-gated calcium channels (L-type & T-type) as well as a sodium/calcium exchanger, but the NMDA channel is particularly adept at allowing large amounts of calcium ion to enter the cell. (benbest.com)
  • After Luo-Rudy passive model was published in 1991 by updating INa (sodium current) and IK, IK1, IKp but keeping the calcium current ICa same as Beeler and Reuter's, Dr. Rudy heard in the annual heart conferences that almost all researchers were very happy about the robustness of Luo-Rudy passive model as used to investigate the clinic phenomena. (scholarpedia.org)
  • Moreover, calcium ions get into the cells from the extracellular space and sarcoplasmic reticulum for muscle contraction, an important feature for human heart. (scholarpedia.org)
  • In 1991, the most arguing issue to formulate a live cardiac cell model was the ambiguity of the calcium ion channels. (scholarpedia.org)
  • Luo-Rudy dynamic model in 1994 not only includes the sodium and potassium channels in Luo-Rudy passive model but also introduces sodium-potassium pump, calcium pump, L-type calcium channel, non-specific calcium-activated channel, sodium-calcium exchanger on the membrane as well as calcium-induced calcium release channel and calcium pump on the membrane of sarcoplasmic reticulum with calcium buffers in the myoplasm. (scholarpedia.org)
  • In the mammalian host, plasmodia invade red blood cells (RBCs) for their asexual propagation. (elifesciences.org)
  • In contrast to the 48-hour blood stage life cycle of asexual parasites, it takes 9-12 days for P. falciparum gametocytes to fully develop inside human red blood cells (RBCs). (biomedcentral.com)
  • Membrane lipids of RBCs are believed to be the foundation of these cells' exquisite stability and deformability [ 21 ]. (biomedcentral.com)
  • This antibody attached to red blood cells (RBCs) in the cold and induced hemolysis when the RBCs are warmed due to complement activity. (medscape.com)
  • This allows for the spread of electrical and chemical signals to cells within a defined radial compartment within the VZ. (jneurosci.org)
  • Our quantitative imaging strategy will be of high value for characterizing the dynamics and function of MCSs between various organelles in living cells. (nature.com)
  • In mature gametocytes many lipids that decrease in the trophozoite and early gametocyte infected red blood cells are regained. (biomedcentral.com)
  • Neutral lipids (serving mainly as caloriometric reserves) increased from 3 % of total lipids in uninfected to 27 % in stage V gametocyte infected red blood cells. (biomedcentral.com)
  • There is enormous demand for lipids due to parasite growth inside the host cell [developing organelles (e.g. nucleus, mitochondria, food vacuoles and apicoplast) surrounded by membranes and accumulating lipids in lipid bodies] and subsequent replication. (biomedcentral.com)
  • After mitosis, daughter cells can either remain proliferative and re-enter the cell cycle or become terminally postmitotic and migrate out of the VZ ( McConnell, 1995 ). (jneurosci.org)
  • The first order variation gives the shape equation and boundary conditions of the lipid membrane: where k n {\displaystyle k_{n}} , k g {\displaystyle k_{g}} , and τ g {\displaystyle \tau _{g}} are normal curvature, geodesic curvature, and geodesic torsion of the boundary curve, respectively. (wikipedia.org)
  • Camerini D, Walz G, Loenen WA, Borst J, Seed B. The T cell activation antigen CD27 is a member of the nerve growth factor/tumor necrosis factor receptor gene family. (bdbiosciences.com)
  • Tumor Necrosis Factor Alpha Antagonism Reveals a Gut/Lung Axis That Amplifies Regulatory T Cells in a Pulmonary Fungal Infection. (uc.edu)
  • This was followed by repeated selection for increasingly aggressive tumor formation from cells recovered from xenograft tumors in immuno-compromised mice, generating the MCF-10CA1a cell line. (biomedcentral.com)
  • Membrane androgen receptors (mAR) are functionally expressed in a variety of tumor-cells including the breast tumor-cell line MCF-7. (biomedcentral.com)
  • Signaling of tumor-cells may further involve up-regulation of pore forming Ca 2+ channel protein Orai1, which accomplishes store operated Ca 2+ entry (SOCE). (biomedcentral.com)
  • The present study explored, whether mAR activation is followed by alterations of Orai1 protein abundance and function in MCF-7 breast tumor cells and addressed the role of actin reorganization and actin signaling to this effect. (biomedcentral.com)
  • Overall, the results presented in this study show a common mechanism of endocytosis for MSC EVs across different cell types and the feasibility to generate functionally enhanced EVs by modifications to parental MSCs. (frontiersin.org)
  • The new LIB was commercialized by Sony in 1991 and in 1992 by A&T Battery (a joint venture company of Asahi Kasei and Toshiba). (nae.edu)
  • Voltage-gated ion channels and ion-exchangers in the cell membrane also regulate ion concentrations. (benbest.com)
  • This is because the ion concentrations inside the cell model is unchanged, i.e., the model cell is always alive or no chance to die. (scholarpedia.org)
  • Using Markov Chain Monte Carlo image simulations, we show that interaction between both organelle types, a defining feature of membrane contact sites (MCSs) can give rise to the observed spatial organelle distribution. (nature.com)
  • However, the nature of the early contact of ribosomes with the membrane, and the involvement of FtsY in this interaction are unknown. (rupress.org)
  • Publications] Araki,S.: 'Role of the Cーterminal region of smg p25A in its interaction with membranes and the GDP/GTP exchange protein. (nii.ac.jp)
  • The colocalisation with laminin indicates a mechanism of interaction between smooth muscle cells and mast cells that may be important in the role of mast cells in the process of fibrosis. (bmj.com)
  • cells are activated by interaction with antigens and obtain T indicated that the cell lines representing a defined cell help, they mature into terminally differentiated plasma stage generally presented a high similarity in over- cells secreting large amounts of antibodies [10 -12]. (lu.se)
  • However, unlike cold hemagglutinin disease, in which the IgM-complement interaction results in the cells' removal (via extravascular phagocytosis), paroxysmal cold hemoglobinuria occurs upon completion of complement lysis within the vascular circulation. (medscape.com)
  • In particular, the EVC2 protein is thought to help regulate a signaling pathway known as Sonic Hedgehog, which plays roles in cell growth, cell specialization, and the normal shaping (patterning) of many parts of the body. (medlineplus.gov)
  • However, treatment of membranes with fatty acid-free bovine serum albumin reduced the basal [ 35 S]GTPγS binding in a concentration-dependent manner and allowed the responsiveness and pharmacology at GPR40 of each of the fatty acids thiazolidinediones and a novel small-molecule agonist to be uncovered. (aspetjournals.org)
  • Effects of taurine and ketamine on bovine retinal membrane lipid peroxidation. (cdc.gov)
  • The effects of the ischemic protectants taurine (107357) (TA) and ketamine (6740881) (KE) on bovine retinal membrane lipid peroxidation were investigated. (cdc.gov)
  • His research is in membrane biophysics. (edu.au)
  • Interdisciplinary approaches to the study of biological membranes[J]. AIMS Biophysics, 2020, 7(4): 267-290. (aimspress.com)
  • Here we show that in cells depleted of the SRP protein, Ffh or the translocon component SecE, the ribosomal targeting pathway is blocked downstream and unprecedented, membrane-bound FtsY-ribosomal complexes are captured. (rupress.org)
  • We have found that the C-terminal systeine residues of smg p21B, rhoA p21, and smg p25A are geranylgeranylated, and that these prenylation are essential for each small G protein to bind to membranes. (nii.ac.jp)
  • Phenylcarbamates, pyridazinones, triazines, triazinones, and uracils are herbicides that inhibit photosynthesis by binding to the Q B -binding niche on the D1 protein of the photosystem II complex in chloroplast thylakoid membranes. (weedscience.org)
  • TAC treatment of MCF-7 cells was followed by Rac1 activation, actin polymerization, transient increase of Orai1transcript levels and protein abundance, and transient increase of SOCE. (biomedcentral.com)
  • In a first step, confocal microscopy was employed to visualize the effect of TAC on the Orai1 protein abundance at the MCF-7 cell membrane surface. (biomedcentral.com)
  • As illustrated in Fig. 1 , mAR activation was followed by a rapid increase of Orai1 protein abundance at the surface of MCF-7 cells. (biomedcentral.com)
  • This was also observed when human embryonic kidney (HEK) 293 cells were transfected with a GPR40-Gα q fusion protein. (aspetjournals.org)
  • The EVC2 protein is found in primary cilia, which are microscopic, finger-like projections that stick out from the surface of cells and are involved in signaling pathways that transmit information between cells. (medlineplus.gov)
  • Influence of spatially segregated IP-producing pathways on spike generation and transmitter release in Purkinje cell axons. (sppin.fr)
  • Identification of the pathways responsible for redistribution of ions and cell water in living cells is hampered by their strong interdependence. (researchgate.net)
  • Recently, we have developed software that allows, using a minimum of required experimental data, to find the characteristics of ion homeostasis and a list of all unidirectional fluxes of monovalent ions through the main pathways in the cell membrane both in a balanced state and during the transient processes. (researchgate.net)
  • The CD27 antibody, clone L128, is derived from hybridization of mouse Sp2/0 cells with spleen cells from BALB/c mice immunized with activated peripheral blood lymphocytes. (bdbiosciences.com)
  • immature cell is then subjected to negative selection to delete grouped based on their previously defined pheno- self-reactive cells before it leaves the BM to enter peripheral typic features, and a gene expression pattern for lymphoid organs, where it becomes a mature B cell [9]. (lu.se)
  • Zinc-binding metalloproteases that are members of the type II integral membrane metalloproteases. (bvsalud.org)
  • During erythropoiesis, the cells start to produce hemoglobin, lose nuclei and organelles, and induce plasma membrane remodeling. (elifesciences.org)
  • In a recent study, activation of mAR by dehydrotestosterone (DHT) in prostate cancer cells was reported to induce rapid Ca 2+ influx via Orai that was important for rapid androgen effects [ 31 ]. (biomedcentral.com)
  • However, liver cirrhosis and intestinal stricture formation are not common in mast cell disease, indicating that besides mast cells additional factors or specific stimulation of mast cells may be necessary to induce severe fibrosis. (bmj.com)
  • Mitochondria receive cholesterol from late endosomes and lysosomes (LE/LYSs) or from the plasma membrane for production of oxysterols and steroid hormones. (nature.com)
  • Besides CD19 + CD138 − B cells, plasmablasts, and plasma cells were enriched in the tongue of mice colonized with C. albicans suggesting a potential role of B lymphocytes during oral fungal colonization. (frontiersin.org)
  • Unexpectedly, shortly after Wnt treatment, we detected the dephosphorylated form of β-catenin at the plasma membrane, where it displayed a discontinuous punctate labeling. (silverchair.com)
  • The use of cell lines does, however, introduce a risk the immunoglobulin (Ig)-secreting plasma cell in the spleen, of obtaining cell line-specific features as a result of the trans- gut, or BM [1, 2]. (lu.se)
  • Membrane-bound ribosomes in E. coli were extensively studied over 20 years ago. (rupress.org)
  • Luo and Rudy models were published at 1991 [1] (passive) and 1994 [2] (dynamic) in Circulation Research by providing the computational formula for the action potential of a single ventricular cell. (scholarpedia.org)
  • 2009) Progestin and thrombin regulate tissue factor expression in human term decidual cells. (scirp.org)
  • Zinc Induces Dendritic Cell Tolerogenic Phenotype and Skews Regulatory T Cell-Th17 Balance. (uc.edu)
  • A cell membrane defines a boundary between a cell and its environment. (wikipedia.org)
  • T cell subpopulation phenotypes in filarial infections: CD27 negativity defines a population greatly enriched for Th2 cells. (bdbiosciences.com)
  • This membrane is made up of dense rows of fatty acids. (vitanetonline.com)
  • After expression of GPR40-Gα q in HEK293 cells and membrane preparation basal binding of [ 35 S]GTPγSinGα q immunoprecipitates was high and not elevated substantially by fatty acids. (aspetjournals.org)
  • This has suggested a potential role for GPR40 in the regulation of β-cell responsiveness to free fatty acids and hence as a potential therapeutic target in the regulation of insulin secretion and diabetes. (aspetjournals.org)
  • 1991) were subsequently identified as the Oligosaccharyl transferase 48 kDa subunit (Ost-48) and Glucosidease-2 subunit beta (Li et al. (reactome.org)
  • The objective of this review is to provide a summary of modeling and experimental research efforts on transport phenomena in proton exchange membrane fuel cells (PEMFCs). (asme.org)
  • In contrast, in the submucosa, laminin was exclusively found in the basal lamina of blood vessels where many adherent mast cells were seen. (bmj.com)
  • In particular, the impact of α-spinasterol on the structure and organization of lipid membranes was investigated and compared with those of cholesterol. (mdpi.com)
  • Experimental infections of pigs confirmed that isolates obtained after introduction of ASF into Armenia and the Russian Federation cause acute disease and result in high mortality rates ( www.efsa.europa.eu/en/scdocs/scdoc/1556.htm ). (cdc.gov)
  • Comparison of the experimental and theoretical potential profiles indicates that the two regions of the membrnae that opposed the electrodes acquired a high membrane conductance of the order of 1 S/cm 2 within 2 μs from the onset of the external field. (elsevierpure.com)
  • These studies provide evidence that mast cells with their plethora of mediators may be involved in intestinal fibrosis, a notion supported by the observation of mast cell hyperplasia and activation in a variety of clinical and experimental situations in which fibrosis is prominent. (bmj.com)
  • Finally, experimental investigation on the cell performance of macro and micro PEMFC and DMFC is briefly presented. (asme.org)
  • Fortunately, huge amount of experimental data have been published for cardiac cells in 1980s, even not for formulism. (scholarpedia.org)
  • 1991) Chemical abortion in patients with recurrent fetal loss. (scirp.org)
  • Using microarrays of complementary DNA, we examined gene-expression profiles of more than 50 normal and neoplastic prostate specimens and three common prostate-cancer cell lines. (nature.com)
  • Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. (nature.com)
  • The mutations that cause this condition occur in both copies of the EVC2 gene in each cell. (medlineplus.gov)
  • The mutations that cause Weyers acrofacial dysostosis occur in one copy of the EVC2 gene in each cell. (medlineplus.gov)
  • These results demonstrate distinct patterns of spontaneous [Ca 2+ ] i change in cortical precursor cells and raise the possibility that these dynamics may contribute to the regulation of neurogenesis. (jneurosci.org)
  • Dynamics of T cell responses in HIV infection. (bdbiosciences.com)
  • Goni FM (2014) The basic structure and dynamics of cell membranes: an update of the Singer-Nicolson model. (aimspress.com)
  • During this time, precursor cells undergo interkinetic nuclear migration ( Seymour and Berry, 1975 ) in which cells in the DNA synthetic S phase have their nuclei in the upper third of the VZ. (jneurosci.org)
  • abstract = "Transmembrane potential was induced in a sea urchin egg by applying a microsecond electric pulse across the cell. (elsevierpure.com)
  • Investigation of an optimal cell lysis method for the study of the zinc metalloproteome of Histoplasma capsulatum. (uc.edu)
  • The investigation of the structural features in biological membranes represents a central topic in many aspects of biological science. (aimspress.com)
  • In this article, we describe the main techniques and approaches employed for the investigation of biological membranes, which are characterized by a wide range of the space-time domains. (aimspress.com)
  • Tanford C (1973) The Hydrophobic Effect: Formation of Micelles and Biological Membranes New York: John Wiley and Sons Inc. (aimspress.com)
  • Features of tissue morphogenesis were assessed, including proliferation, basement membrane formation, polarization of alpha-6 beta-4 integrin to the basement membrane, formation of cell:cell junctions, and apoptosis for luminal clearance. (biomedcentral.com)
  • 1 In Crohn's disease, smooth muscle cells are considered to be the predominant cells involved in the process of stricture formation. (bmj.com)
  • In PCH, the red blood cells are targeted by an autoantibody, the Donath-Landsteiner antibody, whose formation is most often triggered by infectious disease or neoplasms. (medscape.com)
  • Universal features of breast cancer include a loss of control of cell proliferation and organization, a loss of cell polarity, as well as a loss of cell: cell adhesion and cell: basement membrane adhesion. (biomedcentral.com)
  • Cell proliferation, migration and cell death are regulated by alterations of cytosolic Ca 2+ activity [ 20 - 23 ]. (biomedcentral.com)
  • Deposition of collagen and proliferation of smooth muscle cells are the response to chronic inflammation and injury of the submucosa leading to fibrosis and thickening of the submucosa and the smooth muscle layers of the bowel wall. (bmj.com)
  • CONCLUSIONS The large accumulation of mast cells in the muscle layer of strictured bowel suggests a functional role for these cells in the hypertrophic and fibrotic response of the smooth muscle cells. (bmj.com)
  • In fibrosing colonopathy, a complication observed in children with cystic fibrosis treated with high strength pancreatic enzyme replacement therapy, an accumulation of mast cells was observed in the intestinal strictures. (bmj.com)
  • CD117 by immunohistochemical methods sion molecules, involved in cell-cell and in order to clarify the role of the infiltrating cell matrix interactions and thought to take inflammatory cells in the pathomechanisms part in cell motility [ 2,3 ]. (who.int)
  • Mechanistic studies of the toxicity of zinc gluconate in the olfactory neuronal cell line Odora. (uc.edu)
  • METHODS Mast cells were visualised by immunohistochemical staining of the mast cell specific proteases chymase and tryptase. (bmj.com)
  • The current study reports data on the membrane properties of the phytosterol (3β,5α,22 E )-stigmasta-7,22-dien-3-β-ol (α-spinasterol), which represents an important component of argan oil and have not been investigated so far in molecular detail. (mdpi.com)
  • The matched series of normal MCF-10A, pre-malignant MCF-10AT, and malignant MCF-10CA1a cells offers a unique opportunity to study the mechanisms of malignant progression both in a three-dimensional microenvironment and in the same cell background. (biomedcentral.com)
  • The present study explored the effect of membrane androgen receptor (mAR) activation on Ca 2+ signaling in MCF-7 breast cancer cells. (biomedcentral.com)
  • It incited Dr. Luo to fabricate a good cardiac single cell model for the arrhythmia study when Dr. Luo joined Dr. Rudy's lab in June 1988. (scholarpedia.org)
  • 7 , 8 In systemic mast cell disease, association of fibrosis and mast cell infiltrates has been documented in the liver, spleen, lymph nodes, and bone marrow. (bmj.com)
  • Human mesenchymal stem cells (HMSCs) are multipotent somatic stem cells that can be isolated from a variety of tissues such as the bone marrow, adipose tissue, and dental pulp. (frontiersin.org)
  • B lymphocyte development is a highly ordered process pro- expression analysis without the use of intermediate amplifica- ceeding from the progenitor cells in the bone marrow (BM) to tion steps. (lu.se)
  • Glial cells are primarily produced in a second germinal zone, the subventricular zone that is located superficially to the VZ. (jneurosci.org)
  • Glial cell production increases as neurogenesis declines, peaking during the early postnatal period ( Bayer and Altman, 1991 ). (jneurosci.org)
  • Our data also support the view that all types of CNS glial cells play an important, irreplaceable role in NDP. (hindawi.com)
  • 5 Richter et al 6 reported elevated mast cell numbers in association with increased transforming growth factor-β immunoreactivity in radiation induced enteropathy in rats, which is characterised by intestinal wall fibrosis, serosal thickening, and chronic ulceration. (bmj.com)
  • Little is known about molecular mecha- desmosomal glycoproteins, resulting in the nisms affecting mast cell and T lympho- loss of keratinocyte cell-cell adhesion [ 1 ]. (who.int)
  • Sterols play a unique role for the structural and dynamical organization of membranes. (mdpi.com)