1989 15 chromosomes human pair 15. Medical search. Frequent questions

An important breakthrough in horse Y chromosome research came with the availability of new genomics tools and resources, such as large-insert genomic bacterial artificial chromosome (BAC) libraries (for review, see Rubes et al. (veteriankey.com)
The sequencing of the zebra finch Taeniopygia guttata genome, in combination with targeted bacterial artificial chromosome (BAC) sequencing, has allowed us to characterize an MHC from a highly divergent and diverse avian lineage, the passerines. (biomedcentral.com)

We have constructed a genetic linkage map of 17 markers on the long arm of human chromosome 21, including six genes and two anonymous loci with a variable number of tandem repeats. (johnshopkins.edu)
The yeast ML01 was modified using a shuttle vector containing a chromosome integration cassette with genes for malolactic enzyme, malate transporter (permease), regulatory genes and a sequence directing homologous recombination at a chromosomal locus (not specified in the FDA report), and the antibiotic phleomycin gene was used as a selectable marker via another plasmid. (i-sis.org.uk)
Interestingly, the first genome-wide CRISPR interference/activation screens to discover susceptibility genes of oxidative stress in induced pluripotent stem cell (iPSC)-derived human neurons identified PSAP. (nature.com)
When the genetic material within the living cells, i.e. genes are working properly, the human body can develop and function smoothly. (faqs.org)
Tn 10 has a composite structure and it is composed of a pair of insertion sequence elements (IS 10 ) flanking five genes. (wikimili.com)
The Tn 10 transposon is often used in genetics to transfer and select-for genes of interest from one organism into the chromosome of another. (wikimili.com)
Cytogenetic (FISH) evidence and the genome assembly itself place core MHC genes on as many as four chromosomes with TAP and Class I genes mapping to different chromosomes. (biomedcentral.com)
The deletion of varying lengths of chromosomal material along the short arm of chromosome 11 is the underlying defect, and developmental abnormalities are related to the contiguous loss of neighboring genes. (medscape.com)

Sequencing refers to determining the order of base pairs that make up the genome. (nature.com)
Diehn M, Bhattacharya R, Botstein D, Brown PO "Genome-Scale Identification of Membrane-Associated Human mRNAs. (openwetware.org)
To study the genomic divergences among hominoids and to estimate the effective population size of the common ancestor of human and chimpanzee we selected 53 autosomal intergenic noncoding DNA segments from the human genome and sequenced them in a human, chimpanzee, gorilla, and orangutan. (ncl.edu.tw)

Compared to autosomes and the X chromosome, relatively few numerical or structural cytogenetic abnormalities have been reported for ECAY. (veteriankey.com)
Abnormalities that affect autosomes (the 22 paired chromosomes that are alike in males and females) are more common than those that affect. (msdmanuals.com)

1970. p. 15-37. (cdc.gov)

The original anti-phleomycin plasmid did not contain a sequence allowing it to be integrated into the yeast chromosome and the plasmid was therefore unstable and frequently lost from the yeast cell [1]. (i-sis.org.uk)
F-plasmid has a parS sequence cluster ( parS F , also called sopC ) composed of twelve repeats of a 16 bp consensus sequence, each separated by 27 base-pair spacer sequences ( Helsberg and Eichenlaub, 1986 ). (biorxiv.org)

We thank Drs. H. Donis-Keller and P. Green of Collaborative Research, Inc., for providing the genotypic data for five loci on chromosome 21 (Donis-Keller et al. (johnshopkins.edu)
Genetic correlations between loci on different chromosomes can be high and can generate false positive linkage. (nervenet.org)
Recombinant inbred (RI) strains have been used to map a wide range of Mendelian loci and quantitative traits (Taylor, 1989). (nervenet.org)

CD99 antigen (Cluster of differentiation 99), also known as MIC2 or single-chain type-1 glycoprotein, is a heavily O-glycosylated transmembrane protein that is encoded by the CD99 gene in humans. (wikipedia.org)
The tau protein exists as multiple protein isoforms in the adult human CNS, generated by alternative splicing of the MAPT gene. (researchsquare.com)
Tau is present in the adult human CNS as multiple protein isoforms generated by alternative splicing, with either 0, 1 or 2 N-terminal inserts (0N, 1N, 2N) and either 3 or 4 C-terminal repeats (3R, 4R)(4). (researchsquare.com)
The fate of yeast and plant DNA, as monitored by yeast chitinase gene and the plant chlorophyll a/b binding protein gene and micro-satellite markers showed that large DNA markers were present in must (the starting fermentation mixture of mainly yeast and grape juice), while the 250 base pair micro-satellites were present in both must and young wine for up to six months [9]. (i-sis.org.uk)
Klapholz-Brown Z, Walmsley GG, Nusse YM, Nusse R, Brown PO "Transcriptional program induced by wnt protein in human fibroblasts suggests mechanisms for cell cooperativity in defining tissue microenvironments. (openwetware.org)
For the phylogenetic relationships among the arboreal members of Cercopithecus , several types of molecular data, including X and Y chromosome DNA sequences, protein sequences and karyotypes, recognize a clade containing a cephus species group and a mitis group. (biomedcentral.com)
Macrophage stimulating protein (MSP) was discovered as a serum protein that promoted mouse macrophage motility ( 13 ), and was later purified to homogeneity from human plasma ( 14 ). (spandidos-publications.com)
Duplex PCR using primers based on the chromosome (Y) in accordance with the sex-determining gene DEAD-box Y-linked protein (DBY) simultaneously used with BMC1009 locus were amplified as an internal control per each reaction. (aejournal.ir)

V. faba has a diploid (2n) chromosome number of 12 (six homologous pairs). (wikipedia.org)

In some embodiments, the fitness is defined as a population genetic behavior, over multiple generations, of translocation chromosomes in populations comprising both translocation-bearing individuals and non-translocation-bearing individuals. (justia.com)
In some embodiments, the high frequency is defined as when translocation-bearing versions of chromosomes make up greater than about 90% of the total chromosomes in a population as compared to wild type versions of the chromosomes involved in generating the translocation. (justia.com)
In some embodiments, the rapid rate is defined as replacement of at least 90% of the wild type population chromosomes by the translocation-bearing altered insect population (translocation) after at most 5 generations. (justia.com)
In a balanced translocation, genetic material is exchanged with material from another nonhomologous chromosome, and the chromosome count is maintained at 46. (msdmanuals.com)
this is an unbalanced translocation, resulting in a chromosome count of 45. (msdmanuals.com)

The precise stoichiometry of tau isoforms is tightly regulated: the levels of 3R and 4R in the adult human CNS are approximately equal, and this appears to have a direct influence on neuronal viability, as mutations in MAPT that disrupt tau splicing are causative of frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP17T) (5,6). (researchsquare.com)

2009), chromosome flow sorting and microdissection technology, and various genomic DNA amplification systems (Telenius et al. (veteriankey.com)
Looking to the future, the pairing of integrative taxonomy approaches with multi-locus genomic sequencing and phenomic techniques, such as transcriptomics and proteomics, holds great potential to resolve many unknowns in fungal taxonomic classification. (frontiersin.org)

We previously localized a Quantitative Trait Locus for HPFH in an extensive Asian-Indian kindred to chromosome 6q23. (biomedcentral.com)

1994 ). In humans, there have been a number of recent studies demonstrating enhanced functions relevant to social behavior following oxytocin application in healthy adults (Heinrichs et al. (biomedcentral.com)

and human spermatogenic stem cell culture to treat azoospermia, and to preserve fertility in pre-pubertal boys undergoing cancer treatment. (infertile.com)
Cancer has been in existence longer than human beings, and man has been facing the illness ever since he made his appearance on Earth. (jcancer.org)
Amazingly, the first human cancer gene was cloned only thirty years ago. (jcancer.org)
The first description of human cancer can be found in the Edwin Smith Papyrus dated 3000 BC that illustrated a case of breast cancer. (jcancer.org)

The NDDB on its side offers technical assistance for balanced diet, increase in milk production etc and devised a plan known as National Dairy Plan (NDP) with a good span of 15 years hence. (paperzz.com)
The travelers were predominantly females (57%: 414/730), with a median age of 28 years (range 15-75). (mirnamimic.com)
In the last 15 years, efforts have been made to shift the discussion of species delimitation away from a preset list of criteria and toward an understanding of the community-level processes driving patterns of diversification ( de Queiroz, 2007 ). (frontiersin.org)
Surveillance data show that 85-90% of women reported to have primary and secondary syphilis in the United States are in the reproductive age group of 15-44 years. (glowm.com)
The strongest relationship between birthplace UV and melanoma was for 15-19 years of age at diagnosis. (cdc.gov)
AN - check the tag INFANT HN - 2008 FX - Child Nutrition FX - Infant Nutrition Physiology FX - Milk FX - Milk, Human DH - Adolescent Nutrition DI - 052508 MN - SP6.021.067 MS - Nutrition of persons 10 through 19 years of age. (bvsalud.org)
The collection of these reports provides details of the scientific activities over fifteen years, presented in the contexts of a number of themes that has characterized the work at the division. (lu.se)

This polymorphism is primarily attributed to the various amount of Y heterochromatin, though earlier studies also suggest variation in the euchromatic portion of the chromosome (Power, 1988). (veteriankey.com)

Unusually for a gene present on the X chromosome, the CD99 gene does not undergo X inactivation, and it was the first such pseudoautosomal gene to be discovered in humans. (wikipedia.org)
Therefore, microdissected Y-chromosome probes are good for FISH but not suitable for cloning and sequencing of the male-specific or pseudoautosomal regions of the chromosome. (veteriankey.com)

These syndromes result from the loss of chromosomal material from the short arm of chromosome 11. (medscape.com)
The pathogenic germline deletion of varying lengths of chromosomal material along the short arm of chromosome 11, including WT1 and PAX6 , is the underlying defect. (medscape.com)
WAGR syndrome is caused by the contiguous loss of chromosomal material from the short arm of chromosome 11. (medscape.com)

Numerous translocations have been observed uniquely in wine yeasts and such chromosome rearrangements involving transgenes can lead to unexpected toxicity in the final product [8]. (i-sis.org.uk)
This might be because rearrangements in the gene-poor Y chromosome have milder effect on the phenotype, as a result of which the affected individuals escape attention and are not subjected to cytogenetic analysis. (veteriankey.com)
The only true Y chromosome structural rearrangements, reported so far, are large-scale ECAY deletions in 64,XY sex reversal mares (Raudsepp et al. (veteriankey.com)

Subject A has a large deletion on chromosome 11 that removes one copy of the BDNF gene. (medscape.com)

The latter is a Y chromosome that has lost the short arm and replaced it with an identical copy of the long arm. (veteriankey.com)
Based on the amino acid sequence homology and biological activity in macrophages, Shimamoto et al ( 15 ) identified that HLP was identical to MSP ( 15 ). (spandidos-publications.com)

The probes have been used for molecular hybridizations (fluorescence in situ hybridization, or FISH) in clinical cytogenetics, Y chromosome mapping, sequencing, gene discovery, and comparative Y chromosome studies between the horse and other equids/ Perssodactyls. (veteriankey.com)

Additionally, there are two reports about infertile stallions having XXY sex chromosomes - an equine counterpart to human Kleinfelter syndrome (Kubien et al. (veteriankey.com)
In the other half, one parent (almost always the mother), who does not have Down syndrome, has only 45 chromosomes, one of which is t(14;21). (msdmanuals.com)

This article is part of a Special Issue entitled: Molecular Genetics of Human Reproductive Failure. (infertile.com)

The purpose of this review is to summarize science-based new treatments for human reproductive failure and future developments. (infertile.com)

Soen Y, Mori A, Palmer TD, Brown PO "Exploring the regulation of human neural precursor cell differentiation using arrays of signaling microenvironments. (openwetware.org)

The movement of the body accompanies the human being since the prenatal period and for it to be perfected and specialized, a multifactorial system that encompasses bodily responses and the capacity for perception must be fully functioning. (bvsalud.org)

Disruptions to tau splicing are associated with a number of tauopathies, however, in vitro and in vivo models to understand the consequences of disrupted tau splicing have been lacking, due in part to species differences in tau splicing and the developmental regulation of tau in human neurons. (researchsquare.com)
The directed differentiation of induced pluripotent stem cells (iPSC) into specific neuronal subtypes provides an unlimited supply of human neurons that can be used to study disease mechanisms. (researchsquare.com)

1989) was a pseudo-hermaphrodite, and the most recent case (our unpublished data) was an intersex with ambiguous external genitalia. (veteriankey.com)
14 , 15 , 16 , 17 , 18 , 19 A recent review of US studies with HIV seroprevalence data among syphilis patients highlights the high HIV seroprevalence in this population. (glowm.com)
This study focuses on two subjects: the divergences between human and the great apes, and an in-depth research of the divergence between human and chimpanzee using a relatively large data set. (ncl.edu.tw)
These data are discussed in terms of three exposure periods: acute (14 days or less), intermediate (15-364 days), and chronic (365 days or more). (cdc.gov)

Sood R, Zehnder JL, Druzin ML, Brown PO "Gene expression patterns in human placenta. (openwetware.org)

The switch from maternal to zygotic developmental programs is associated with large-scale modification of chromosomes. (biomedcentral.com)

Rubins KH, Hensley LE, Wahl-Jensen V, Daddario Dicaprio KM, Young H, Reed DS, Jahrling PB, Brown PO, Relman DA, Geisbert TW "The temporal program of peripheral blood gene expression in the response of non-human primates to Ebola hemorrhagic fever. (openwetware.org)
Palmer C, Diehn M, Alizadeh AA, Brown PO "Cell-type specific gene expression profiles of leukocytes in human peripheral blood. (openwetware.org)

need Ethical humans n't internal as R-modules? (hawksawblades.com)

They were known as cohesive ends because they could form complementary base pairs with any other end produced by the same enzyme. (faqs.org)
AMINO ACID MEASUREMENTS Human studies Reduced GABA uptake during microdialysis has been mentioned and there are reports of reduced levels of GABA in the CSF of chronic epileptics and of its synthesising enzyme glutamic acid decarboxylase GAD) in some samples of temporal lobe tissue removed during surgery to alleviate focal seizures. (forexassessment.com)

Genomes of individuals strains typically incorporate 45-55 recombinations between parental chromosomes. (nervenet.org)

However, over half of the recombination events in either sex occur distally, in 21q22.3, although this region accounts for only about 15% of the physical length of chromosome 21. (johnshopkins.edu)

When CD99 expression is knocked down in human cells with Ewing's sarcoma and those cells are grafted onto mice, tumor and bone metastasis development is reduced. (wikipedia.org)
Relevant of mutagenicity and clastogenici- angiosarcomas of the liver, which carcinogens discussed in this chap- ty, including the induction of sister are rare tumours, were identified in ter do not include pharmaceutical chromatid exchange (SCE), chro- humans, rats, and mice exposed to drugs classified in Group 1, which mosomal aberrations (CA), and mi- vinyl chloride. (who.int)
or each of these agents, carcinogenicity in rats and/or mice, els, differences in exposure con- there was sufficient evidence of car- for example for the liver (aflatoxins, ditions between studies in animals cinogenicity from studies in rats and/ trichloroethylene [TCE], and vinyl and in humans, or limitations in Part 1 · Chapter 1. (who.int)

The cohesive ends generated by the restriction endonuclease made it possible to join double helical DNA fragments from different sources by complementary base-pairing. (faqs.org)
The 6-9 base pairs that flank the sequence also influence selection of the insertion site. (wikimili.com)
The results are reliable, there are two bands 280-310 (polymorphic band) and 180 base pairs (bp) in male deer and 280-310 (polymorphic band) base pairs (bp) in female deer showed. (aejournal.ir)
Despite being an inherent characteristic of human life, movement needs a base, which is the perception of the body itself, and the possibilities of movement based on the notion of the body. (bvsalud.org)

In this chapter, electrophilic agents nogenicity from studies of exposed (benzene, 1,3-butadiene, and eth- include direct-acting electrophilic humans. (who.int)

The average sequence divergence was only 1.24% ± 0.07% for the human-chimpanzee pair, 1.62% ± 0.08% for the human-gorilla pair, and 1.63% ± 0.08% for the chimpanzee-gorilla pair. (ncl.edu.tw)
ParABS partition systems, comprising the centromere-like DNA sequence parS, the parS -binding ParB-CTPase and the nucleoid-binding ParA-ATPase, ensure faithful segregation of bacterial chromosomes and low-copy-number plasmids. (biorxiv.org)

LOAELs or NOAELs should also help in determining whether or not the effects vary with dose and/or duration, and place into perspective the possible significance of these effects to human health. (cdc.gov)

All of the chemicals discussed of this chemical was raised to carci- lung and the nasal cavity were iden- here are IARC Group 1 agents and nogenic to humans (Group 1) based tified as target organs in humans as such can be characterized as on strong mechanistic evidence and rats, respectively. (who.int)

Since the long arm of ECAY carries the MSY and the PAR, the cells with i(Y) are genetically similar to those with Y chromosome disomy (YY). (veteriankey.com)
Faithful segregation of replicated chromosomes is essential for efficient proliferation of cells. (biorxiv.org)

mediating resistance to colistin, in isolates obtained from Jörg Overmann, Alexander Goesmann, humans and animals ( 1 ). (cdc.gov)
Public health officials and others concerned with appropriate actions to take at hazardous waste sites may want information on levels of exposure associated with more subtle effects in humans or animals (LOAELs) or exposure levels below which no adverse effects (NOAELs) have been observed. (cdc.gov)

the wild species has pods that are 5 to 10 cm (2 to 4 in) long and 1 cm diameter, but many modern cultivars developed for food use have pods 15 to 25 cm (6 to 10 in) long and 2-3 cm thick. (wikipedia.org)
They are round to oval and have a 5-10 mm diameter in the wild plant, but are usually flattened and up to 20-25 mm long, 15 mm broad and 5-10 mm thick in food cultivars . (wikipedia.org)

Anatomy66

Organisms8

Diseases26

Chemicals and Drugs29

Analytical, Diagnostic and Therapeutic Techniques and Equipment26

Psychiatry and Psychology1

Phenomena and Processes174

Disciplines and Occupations2

Technology, Industry, Agriculture2

Information Science4

Health Care1

Bacterial artificial2

Genes8

Genome3

Autosomes2

19701

Plasmid2

Loci3

Protein8

Homologous1

Translocation5

Parkinsonism1

Genomic2

Quantitative1

19941

Cancer4

Years7

Variation1

Pseudoautosomal2

Chromosomal3

Rearrangements3

Deletion1

Identical2

Hybridization1

Syndrome2

Genetics1

Reproductive1

Precursor1

Accompanies1

Neurons2

Data4

Placenta1

Developmental1

Gene expression2

Ethical1

Enzyme2

Typically1

Region1

Mice3

Base4

Studies1

Sequence2

Significance1

Group1

Cells2

Animals2

Long2