• myocardial
  • Brain natriuretic peptide: a marker of myocardial dysfunction and prognosis during severe sepsis," Critical Care Medicine , vol. 32, no. 3, pp. 660-665, 2004. (hindawi.com)
  • 17 18 19 In addition, most studies have based prediction on objective descriptors of LV size and performance, which reflect the impact of extrinsic and varying loading factors as well as intrinsic myocardial characteristics. (ahajournals.org)
  • angiotensin
  • 2 7 8 9 Moreover, ANP-(1-28) inhibits the hypertrophic effects of angiotensin II and transforming growth factor-β on postconfluent VSM cultured from adult rat aorta. (ahajournals.org)
  • Aldosterone synthesis is stimulated by several factors: increase in the plasma concentration of angiotensin III, a metabolite of angiotensin II increase in plasma angiotensin II, ACTH, or potassium levels, which are present in proportion to plasma sodium deficiencies. (wikipedia.org)
  • 1981
  • The discovery of ANP was reported in 1981, when rat atrial extracts were found to contain a substance that increased salt and urine output in the kidney. (wikipedia.org)
  • receptor
  • Binding of a natriuretic peptide induces a conformational change in the receptor that causes receptor dimerization and activation. (wikipedia.org)
  • Zheng M, Morgan-Lappe SE, Yang J, Bockbrader KM, Pamarthy D, Thomas D, Fesik SW , Sun Y. Growth inhibition and radiosensitization of glioblastoma and lung cancer cells by small interfering RNA silencing of tumor necrosis factor receptor-associated factor 2 . (vanderbilt.edu)
  • Estrogen receptor (ER) has been shown to transactivate other transcription factors in this manner, despite the absence of an estrogen response element (ERE) in the proximal promoter region of the gene. (wikipedia.org)
  • biological
  • J. E. Towne, C. M. Krane, C. J. Bachurski, and A. G. Menon, "Tumor necrosis factor- α inhibits aquaporin 5 expression in mouse lung epithelial cells," The Journal of Biological Chemistry , vol. 276, no. 22, pp. 18657-18664, 2001. (hindawi.com)
  • 5. Synthesis and biological activity of a natriuretic metabolite of diltiazem and its derivatives. (nih.gov)
  • Both biological and environmental factors appear to play a role. (wikipedia.org)
  • The most underlining factor researchers are starting to take notice of is that it may not just be a vanity, social, or media issue, but it could also be related to biological and or genetic components. (wikipedia.org)
  • responses
  • 4 5 6 ANP-(1-28) is the major circulating form of ANP, 3 and both ANP-(1-28) and CNP-(1-22) inhibit the hyperplastic responses of cultured adult VSM to serum and growth factors. (ahajournals.org)
  • ventricular
  • Ventricular transforming growth factor-β1 and types I and III collagen mRNA levels did not increase at 24 hours and began to increase by 1.4-, 2.8-, and 2.1-fold, respectively, at 3 days. (ahajournals.org)
  • cGMP
  • In 1985, it was discovered that cGMP was able to directly activate the light-dependent response of rod ion channels by studying light-adapted retina of frogs. (wikipedia.org)
  • Identification
  • Identification of factors responsible for this difference might provide insight into the pathophysiology of salt-sensitive hypertension and thereby suggest new therapeutic strategies. (ahajournals.org)
  • expression
  • However, molecular markers of hypertrophy (such as α-skeletal actin and atrial myosin light chain-1) were expressed with a wider distribution, suggesting that their induction was secondary to the expression of the transgene. (ahajournals.org)