• myocardial
  • Brain natriuretic peptide: a marker of myocardial dysfunction and prognosis during severe sepsis," Critical Care Medicine , vol. 32, no. 3, pp. 660-665, 2004. (hindawi.com)
  • 17 18 19 In addition, most studies have based prediction on objective descriptors of LV size and performance, which reflect the impact of extrinsic and varying loading factors as well as intrinsic myocardial characteristics. (ahajournals.org)
  • angiotensin
  • 2 7 8 9 Moreover, ANP-(1-28) inhibits the hypertrophic effects of angiotensin II and transforming growth factor-β on postconfluent VSM cultured from adult rat aorta. (ahajournals.org)
  • Aldosterone synthesis is stimulated by several factors: increase in the plasma concentration of angiotensin III, a metabolite of angiotensin II increase in plasma angiotensin II, ACTH, or potassium levels, which are present in proportion to plasma sodium deficiencies. (wikipedia.org)
  • 1981
  • The discovery of ANP was reported in 1981, when rat atrial extracts were found to contain a substance that increased salt and urine output in the kidney. (wikipedia.org)
  • biological
  • J. E. Towne, C. M. Krane, C. J. Bachurski, and A. G. Menon, "Tumor necrosis factor- α inhibits aquaporin 5 expression in mouse lung epithelial cells," The Journal of Biological Chemistry , vol. 276, no. 22, pp. 18657-18664, 2001. (hindawi.com)
  • 5. Synthesis and biological activity of a natriuretic metabolite of diltiazem and its derivatives. (nih.gov)
  • Both biological and environmental factors appear to play a role. (wikipedia.org)
  • The most underlining factor researchers are starting to take notice of is that it may not just be a vanity, social, or media issue, but it could also be related to biological and or genetic components. (wikipedia.org)
  • ventricular
  • Ventricular transforming growth factor-β1 and types I and III collagen mRNA levels did not increase at 24 hours and began to increase by 1.4-, 2.8-, and 2.1-fold, respectively, at 3 days. (ahajournals.org)
  • responses
  • 4 5 6 ANP-(1-28) is the major circulating form of ANP, 3 and both ANP-(1-28) and CNP-(1-22) inhibit the hyperplastic responses of cultured adult VSM to serum and growth factors. (ahajournals.org)
  • cGMP
  • In 1985, it was discovered that cGMP was able to directly activate the light-dependent response of rod ion channels by studying light-adapted retina of frogs. (wikipedia.org)
  • Identification
  • Identification of factors responsible for this difference might provide insight into the pathophysiology of salt-sensitive hypertension and thereby suggest new therapeutic strategies. (ahajournals.org)
  • expression
  • However, molecular markers of hypertrophy (such as α-skeletal actin and atrial myosin light chain-1) were expressed with a wider distribution, suggesting that their induction was secondary to the expression of the transgene. (ahajournals.org)