Loading...
  • illness
  • Although LD is now the most common arthropod-borne illness in the U.S. (more than 150,000 cases have been reported to the Centers for Disease Control and Prevention [CDC] since 1982), its diagnosis and treatment can be challenging for clinicians due to its diverse manifestations and the limitations of currently available serological (blood) tests. (aldf.com)
  • In Europe, associations between tick bites and several skin diseases had been known for decades, but it was not understood that various conditions were part of a single illness. (sfsbm.org)
  • burgdorferi
  • However, a correlation has been found which presents data suggesting that B. burgdorferi found in the United States is the most arthritogenic, whereas the B. afzelii and B. garnii found in Europe and Asia tend to give signs more consistent with dermatological and neuroborreliosis symptoms. (davidson.edu)
  • diagnosis
  • Due to the unrelenting efforts of people who are seeking a cure to this epidemic, many research efforts are underway today to improve testing and diagnosis as well as treatments for Lyme and associated diseases. (natcaplyme.org)
  • After a median follow-up of 51 months, patients with a diagnosis of Lyme disease that met the national surveillance case definition developed by the Centers for Disease Control and Prevention (CDC) had the same profile of symptoms and the same quality-of-life indicators as age-matched controls without Lyme disease. (sfsbm.org)
  • Therefore
  • The implication is that many of these individuals really did not have Lyme disease and therefore did not respond to the treatment . (sfsbm.org)
  • patients
  • Patients with neurodegenerative diseases and behavioral disorders often have systemic bacterial, viral, and/or fungal infections that are important in disease progression and severity. (townsendletter.com)
  • Generally, LD in its later stages can also be treated effectively, but because the rate of disease progression and individual response to treatment varies from one patient to the next, some patients may have symptoms that linger for months or even years following treatment. (aldf.com)
  • On the other hand, patients who were reported to have Lyme disease but who did not meet the CDC's case definition of Lyme disease had increased symptoms and worsening quality-of-life indicators. (sfsbm.org)
  • inflammatory
  • LD manifests itself as a multisystem inflammatory disease that affects the skin in its early, localized stage, and spreads to the joints, nervous system and, to a lesser extent, other organ systems in its later, disseminated stages. (aldf.com)
  • pathogenesis
  • In the last century, however, Dr. Alois Alzheimer did not require amyloid as the pathogenesis for either the disease or for the origin of its plaques. (borrelioosi.net)
  • progression
  • 8 Such infections may also cause disease progression, and since they are usually systemic, they could affect the immune system and other organ systems, resulting in systemic signs and symptoms. (townsendletter.com)
  • cause
  • 1-5 One of the biochemical changes found in essentially all neurological degenerative diseases is the over-expression of oxidative free radical compounds (oxidative stress) that cause lipid, protein, and genetic structural changes. (townsendletter.com)
  • The medical community's division over the cause and cure of persistent Lyme disease symptoms illustrates the indisputable and immediate need for unbiased research. (natcaplyme.org)
  • neurological
  • 1 These diseases are characterized by molecular changes in nerve cells that result in nerve cell degeneration and, ultimately, nerve dysfunction and cell death, resulting in neurological signs and symptoms and, eventually, dementia. (townsendletter.com)
  • found
  • This "Western blot" test identifies specific antibody proteins found in Lyme disease. (natcaplyme.org)
  • A long-term study of 212 Connecticut residents suspected of having Lyme disease found incidences of pain, fatigue, and difficulty with daily activities to be similar to 212 age-matched controls without Lyme disease . (sfsbm.org)
  • incidence
  • For the most part, the causes and mechanisms of this collection of brain diseases remain largely unknown, and they are increasing in incidence in the developed as well as the underdeveloped world. (townsendletter.com)
  • Europe
  • Up to a fifth of Lyme disease is caught while abroad - in particular, the USA, France, Germany, Austria, Scandinavia and eastern and central Europe. (patient.info)
  • Manifestations of what we now call Lyme disease were first reported in medical literature in Europe in 1883. (aldf.com)
  • Academy
  • The American Academy of Neurology (AAN) published a practice parameter in 2001 stating that steroids are probably effective and acyclovir (with prednisone) is possibly effective for the treatment of Bell palsy. (medscape.com)
  • [ 6 , 8 ] Guidelines from the American Academy of Otolaryngology-Head and Neck Surgery Foundation also recommend the use of corticosteroids. (medscape.com)
  • Guidelines from the American Academy of Otolaryngology-Head and Neck Surgery Foundation (AAO-HNSF) were issued in November 2013 that also support the AAN guidelines. (medscape.com)
  • specific
  • Doctors commonly adopt a two-tiered approach to testing for Lyme, so that if the first tier-test, the enzyme-linked immunosorbent assay (ELISA), results are positive, further testing with the more specific and accurate laboratory technique known as immunoblotting is used. (natcaplyme.org)
  • common
  • Lyme disease is less common in the UK. (patient.info)
  • Areas where it is most common tend to be centres of outdoor activity - in particular, the New Forest, Thetford Forest, the South Downs, Exmoor, the Lake District, the North York moors and the Scottish Highlands. (patient.info)