Loading...
  • equina
  • En este trabajo comunicamos un método rápido que permite la amplificación del genoma completo del subtipo 2 (H3N8) del virus de la influenza equina. (scielo.org.ar)
  • El producto obtenido por esta técnica puede ser clonado y utilizado posteriormente en reacciones de secuenciación o de PCR anidada con la finalidad de lograr un diagnóstico rápido y la caracterización del virus de la influenza equina tipo A. Este ensayo de detección puede llegar a ser una valiosa herramienta para el diagnóstico y el análisis de muestras de campo, así como para la realización de estudios moleculares. (scielo.org.ar)
  • vaccine
  • In the 1980s, the virus was characterized, and researchers speculated that it was related to a reassortant influenza A(H1N1) virus vaccine strain, A/PR-8/34 + A/USSR/77, generated in a Soviet laboratory and administered to humans in Mongolia and possibly transmitted from vaccinated humans to camels in a reactivated form ( 5 , 6 ). (cdc.gov)
  • Spread of the disease has been associated with the movement of people, pets, horse equipment and tack where proper biosecurity procedures have not been followed Subclinical infection with virus shedding can occur in vaccinated horses, particularly where there is a mismatch between the vaccine strains and the virus strains circulating in the field. (wikipedia.org)
  • Live attenuated influenza virus vaccine. (blogspot.com)
  • pandemic
  • H3N8 has been identified as the probable cause of the 1889-1890 flu pandemic in humans, and also another epidemic in 1898-1900. (wikipedia.org)
  • Before the identification of H3N8 as the likely cause of the 1889 pandemic, the H2N2 subtype was most commonly suggested as the likely cause. (wikipedia.org)
  • The origin of the 1918 pandemic influenza A virus (IAV) and the reasons for its unusual severity are two of the foremost biomedical mysteries of the past century. (pnas.org)
  • The source, timing, and geographical origin of the 1918-1920 pandemic influenza A virus have remained tenaciously obscure for nearly a century, as have the reasons for its unusual severity among young adults. (pnas.org)
  • Our results suggest that the 1918 pandemic virus originated shortly before 1918 when a human H1 virus, which we infer emerged before ∼1907, acquired avian N1 neuraminidase and internal protein genes. (pnas.org)
  • Hence, although the swine lineage was a direct descendent of the pandemic virus, the post-1918 seasonal H1N1 lineage evidently was not, at least for HA. (pnas.org)
  • The influenza pandemic of 1918-1920 killed an estimated 50 million people, most during a single wave late in 1918 ( 1 , 2 ). (pnas.org)
  • The very elderly, moreover, suffered less influenza-related mortality during the pandemic than in 1911-1917 ( 5 ). (pnas.org)
  • phylogenetic
  • The phylogenetic results, combined with these other lines of evidence, suggest that the high mortality in 1918 among adults aged ∼20 to ∼40 y may have been due primarily to their childhood exposure to a doubly heterosubtypic putative H3N8 virus, which we estimate circulated from ∼1889-1900. (pnas.org)
  • strain
  • In the low virulent strains limited to the respiratory tract, this site is usually a unique arginine (eg: HA1-PEKQI-R 329 -GI-HA2 of the strain A/equine/Miami/1963 (H3N8)/AAA43164). (biomedcentral.com)
  • strains
  • In the Ectodomain, the mutation N/154 2 /T deleted the NGT glycosylation site at position 154 for both strains A/equine/Essaouira/2/2004(H3N8) and A/equine/Essaouira/3/2004(H3N8). (biomedcentral.com)
  • neuraminidase
  • Influenza viruses type A can be further subdivided in different serologically differentiated subtypes according to the structure and composition of two antigenic glycoproteins located in the surface of the virion: haemagglutinin (HA) involved in binding of the virus to host cells and neuraminidase (NA) implicated in release of virus from infected cells. (scielo.org.ar)
  • different
  • The virus can survive in the environment, on different surfaces, for up to 48 hours. (wikipedia.org)
  • It then undertakes a selective review of different strategies of vaccination against equine influenza that have been developed over the last two decades and discusses factors that may influence the efficacy of vaccination. (blogspot.com)
  • responsible
  • Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. (rcsb.org)
  • virion
  • This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. (rcsb.org)
  • known
  • Because little is known about the ecology of influenza viruses in camels, 460 nasal swab specimens were collected from healthy (no overt illness) Bactrian camels in Mongolia during 2012. (cdc.gov)
  • However
  • However, the virus doesn't survive outside of a horse for long The virus is delicate within the environment and easily killed by heat, cold, desiccation, and disinfectants. (wikipedia.org)
  • EQUINA
  • En este trabajo comunicamos un método rápido que permite la amplificación del genoma completo del subtipo 2 (H3N8) del virus de la influenza equina. (scielo.org.ar)
  • El producto obtenido por esta técnica puede ser clonado y utilizado posteriormente en reacciones de secuenciación o de PCR anidada con la finalidad de lograr un diagnóstico rápido y la caracterización del virus de la influenza equina tipo A. Este ensayo de detección puede llegar a ser una valiosa herramienta para el diagnóstico y el análisis de muestras de campo, así como para la realización de estudios moleculares. (scielo.org.ar)