Thirty-eight ortho-substituted polychlorinated biphenyls (PCBs), 13 persistent chlorinated pesticides, and selected pesticide metabolites are measured in serum by high-resolution gas chromatography/isotope-dilution high-resolution mass spectrometry (HRGC/ID-HRMS). (cdc.gov)
To test this hypothesis, we applied high-resolution mass spectrometry analysis to lipid samples obtained from the WT and evol40 strains grown in 1 g/L glucose (glucose), 0.75 g/L phenol (low phenol), or 1.5 g/L phenol (high phenol, evol40 only) as a sole carbon source. (biomedcentral.com)
HPLC is the form of liquid chromatography that is generally used in the pharmaceutical industry, as it can provide the precise results that are required. (europeanpharmaceuticalreview.com)
Although expected at first to be used as a complimentary method to gas chromatography, the pharmaceutical industry now almost exclusively uses HPLC as a chromatographic technique. (europeanpharmaceuticalreview.com)
High performance liquid chromatography (HPLC) is one of the most commonly used analytical techniques in pharma today10. (ddw-online.com)
Liquid9
Like liquid chromatography-mass spectrometry, it allows analysis and detection even of tiny amounts of a substance. (wikipedia.org)
To guarantee that goods pass certain standards, researchers, manufacturers and developers use various technical equipment and analytical techniques , including liquid chromatography, during the development process. (europeanpharmaceuticalreview.com)
Liquid chromatography, most commonly used for purification in the pharmaceutical industry (10), typically employs modified silica or polymer particles as a solid phase, with water, organic solvents, or a mixture of the two as a mobile phase. (ddw-online.com)
Hao C., Helm P.A., Morse D., Reiner E.J., Liquid chromatography-tandem mass spectrometry direct injection analysis of organophosphorus flame retardants in Ontario surface water and wastewater effluent. (dormaj.org)
Solvents2
In addition, replacement of petrochemical-derived hydrocarbon chromatography solvents with supercritical carbon dioxide, and the use of selective adsorbents and reactive resins, are presented as examples of greener approaches to the removal of impurities from pharmaceutical intermediates. (ddw-online.com)
Residual solvents were qualitatively and quantitatively monitored before, during, and following the microwaving step by static headspace-gas chromatography-mass spectrometry. (thevespiary.org)
Pharma4
club-captains.ru/dragon-pharma-winstrol-50-tri-mass-prohormone-review/ Gcms archives - welcome to vancouver's immigration blog. (saazestaan.com)
Several approaches are considered for 'greening' analytical chromatography, where small solvent savings multiplied across the hundreds or thousands of users found in a typical pharma company can add up to significant waste reduction. (ddw-online.com)
However, given the sheer number of analytical chromatography instruments in use throughout the pharma industry, the greening of analytical chromatography remains an important focus as well. (ddw-online.com)
Quadrupole4
In 1964, Electronic Associates, Inc. (EAI), a leading U.S. supplier of analog computers, began development of a computer controlled quadrupole mass spectrometer under the direction of Robert E. Finnigan. (wikipedia.org)
By 1966 Finnigan and collaborator Mike Uthe's EAI division had sold over 500 quadrupole residual gas-analyzer instruments. (wikipedia.org)
A variety of mass spectrometer types, including magnetic sector, quadrupole, time-of-flight, and ion trap, have and will continue to deepen our understanding of the formation and evolution of exploration targets like the surfaces and atmospheres of planets and their moons. (frontiersin.org)
Chromatograph4
The GC-MS is composed of two major building blocks: the gas chromatograph and the mass spectrometer. (wikipedia.org)
The gas chromatograph utilizes a capillary column whose properties regarding molecule separation depend on the column's dimensions (length, diameter, film thickness) as well as the phase properties (e.g. 5% phenyl polysiloxane). (wikipedia.org)
Combining the two processes reduces the possibility of error, as it is extremely unlikely that two different molecules will behave in the same way in both a gas chromatograph and a mass spectrometer. (wikipedia.org)
He distanced himself from research into performance-enhancing drugs until May 1960, or possibly as early as 1959 (conflicting testimonials). (sustanon-250.com)
Greenhouse gases2
At the same time, huge amounts of greenhouse gases have been emitted into the atmosphere, which have induced unexpected climate changes and global warming. (springeropen.com)
Continued exploitation of the world's fossil fuel reserves is unsustainable due to their depleted status and simultaneous steady accumulation of greenhouse gases in the atmosphere. (hindawi.com)
Spectrometer5
The first on-line coupling of gas chromatography to a mass spectrometer was reported in the late 1950s. (wikipedia.org)
The molecules are retained by the column and then elute (come off) from the column at different times (called the retention time), and this allows the mass spectrometer downstream to capture, ionize, accelerate, deflect, and detect the ionized molecules separately. (wikipedia.org)
The mass spectrometer does this by breaking each molecule into ionized fragments and detecting these fragments using their mass-to-charge ratio. (wikipedia.org)
Sometimes two different molecules can also have a similar pattern of ionized fragments in a mass spectrometer (mass spectrum). (wikipedia.org)
Calibration of mass spectrometer response factor vs. concentration is performed using calibration standards containing known concentrations of each 12 C compound and its corresponding 13 C internal standard. (cdc.gov)
Analytical3
Gas chromatography-mass spectrometry (GC-MS) is an analytical method that combines the features of gas-chromatography and mass spectrometry to identify different substances within a test sample. (wikipedia.org)
Although originally invented by Tswett as a purification technique, chromatography has evolved into one of the most widely used analytical technologies in the pharmaceutical industry. (ddw-online.com)
Analytical chromatography is typically performed using a stationary phase column of 4.6mm diameter and 25cm length at a mobile phase flow rate of about 1mL/min. (ddw-online.com)
Pharmaceutical industry1
In this article we focus on challenges and opportunities for greening chromatography, adsorption and other separation technologies currently used in the pharmaceutical industry. (ddw-online.com)
Detection2
Modern flight-capable mass spectrometers, in combination with various sample processing, separation, and ionization techniques enable sensitive detection of chemical biosignatures. (frontiersin.org)
Here, we delve into the search for extraterrestrial chemical and morphological biosignatures and examine several possible approaches to agnostic life detection using mass spectrometry. (frontiersin.org)
Analysis3
Therefore, when an identifying mass spectrum appears at a characteristic retention time in a GC-MS analysis, it typically increases certainty that the analyte of interest is in the sample. (wikipedia.org)
Mass spectrometry : gc-ms analysis with metams package. (saazestaan.com)
Agilent Technologies, a world-renowned brand, manufactures and markets instruments for laboratory testing, measurement and analysis such as gas chromatography systems, mass spectrometry systems, etc. (alternup-medical.com)
The discrimination effect was enhanced by the non-uniform adsorption of gas molecules on the top, side and bottom regions of the resonator. (researchgate.net)
Chromatography relies on the selective partition of different molecules between a stationary phase and a mobile phase, as depicted in Figure 1. (ddw-online.com)
Compounds1
Their capacity to produce mousy compounds was investigated using Stir Bar Sorptive Extraction-Gas Chromatography-Mass Spectrometry (SBSE-GC-MS) and a standardised N -heterocycle assay medium. (oeno-one.eu)
The purpose of this study was to develop and validate a single method for 15 of the HPHC listed PAHs using gas chromatographymass spectrometry (GC-MS). Several aspects of the instrumental method were critical to ensuring a robust method was developed. (enthalpy.com)
Solvent reduction, substitution or elimination has long been a major focus for many areas of green chemistry research (11), including dry cleaning, extractions and organic reactions and processing (12,13), and many of the approaches used in those areas are also useful in reducing solvent waste from chromatography. (ddw-online.com)
Instruments1
Bendix began marketing a gc-ms device in 1959, but the first commercial success was lkb instruments inc. 's model 9000, which debuted in 1965. (saazestaan.com)
Time1
On the other hand, in addition to monitoring multiple pollutants at the same time, electronic nose is one of the most efficient way to eliminate the influences of interfering gas and improve data accuracy (Speller et al. (researchgate.net)
Since its establishment in 1959, Kyocera has provided components for a wide range of markets including industrial equipment, communications devices, medical devices, and renewable energy equipment, and has supported the development of numerous other industries by utilizing technology cultivated over many years of research, development, and manufacturing of fine ceramics. (chemeurope.com)
Separation1
The technique of chromatography was invented by botanist Mikael Tswett in 1903, and originally used for the separation of plant pigments (8,9). (ddw-online.com)
Remains1
Oxymorphone was approved for use in the United States in 1959 and remains in clinical use. (nih.gov)
In contrast, preparative chromatography is carried out using much larger columns, sometimes in excess of 1 metre diameter, with mobile phase flow rates of many litres per minute. (ddw-online.com)
Life2
An important impetus for the continuing exploration of Mars, Europa, Enceladus, Titan, and Venus involves assessing the habitability of solar system bodies and, ultimately, the search for life-a monumental effort that can be advanced by mass spectrometry. (frontiersin.org)
Events in pregnancy, delivery, and infancy and long-term effects on globalquality of life: results from the Copenhagen Perinatal Birth Cohort 1959-61. (medscihypotheses.com)
Distribution1
AIR LIQUIDE is a French company and market leader in the distribution of gases for medical use as well as in the manufacture of medical suction devices, flow meters, humidifiers and medical furniture. (alternup-medical.com)
Properties1
Ustinov V.M. Effect of the parameters of AlN/GaN/AlGaN and AlN/GaN/InAlN heterostructures with a two-dimensional electron gas on their electrical properties and the characteristics of transistors on their basis. (iairas.ru)