• Y. pestis is thought to be descended from Y. pseudotuberculosis, differing only in the presence of specific virulence plasmids. (wikipedia.org)
  • The Yop-Ysc T3SS is a critical component of virulence for Yersinia species. (wikipedia.org)
  • However, there were no genomic data on the Yersinia species with more limited virulence potential, frequently found in soil and water environments. (biomedcentral.com)
  • This work underscores the importance of the acquisition of horizontally transferred genes in the evolution of Y. pestis and points to virulence determinants that have been gained and lost on multiple occasions in the history of the genus. (biomedcentral.com)
  • Proteogenomic discovery of sORF-encoded peptides associated with bacterial virulence in Yersinia pestis. (nih.gov)
  • Against the assumptions of historians and scientists for over a century and what continues to be inscribed in medical and history texts alike, the Black Death was not the same disease as that rat-based bubonic plague whose agent (Yersinia pestis) was first cultured at Hong Kong in 1894. (historycooperative.org)
  • citation needed] Several complete genome sequences are available for various strains and subspecies of Y. pestis: strain KIM (of biovar Y. p. medievalis), and strain CO92 (of biovar Y. p. orientalis, obtained from a clinical isolate in the United States). (wikipedia.org)
  • Yersinia - Taxon details on Integrated Taxonomic Information System (ITIS). (wikimedia.org)
  • Similar to other Yersinia species, it tests negative for urease, lactose fermentation, and indole. (wikipedia.org)
  • It also hosts two other plasmids, pPCP1 (also called pPla or pPst) and pMT1 (also called pFra) that are not carried by the other Yersinia species. (wikipedia.org)
  • Y. pestis was discovered in 1894 by Alexandre Yersin, a Swiss/French physician and bacteriologist from the Pasteur Institute, during an epidemic of the plague in Hong Kong. (wikipedia.org)
  • Yersinia pestis is a parasite of its host, the rat flea, which is also a parasite of rats, hence Y. pestis is a hyperparasite. (wikipedia.org)
  • Following introduction into a human through flea bite [ 16 ], Y. pestis is engulfed by macrophages and taken to the regional lymph nodes. (biomedcentral.com)
  • citation needed] A comprehensive and comparative proteomics analysis of Y. pestis strain KIM was performed in 2006. (wikipedia.org)
  • Yersinia genomes had a similar global partition of protein functions, as measured by the distribution of Cluster of Orthologous Groups families. (biomedcentral.com)
  • Soman was originally developed as an insecticide in Germany in 1944. (cdc.gov)
  • Like Y. pestis , the enteropathogenic Yersiniae can escape macrophages and multiply outside host cells, but unlike their more virulent cogener, they only usually cause self-limiting inflammatory diseases. (biomedcentral.com)
  • Antonie van Leeuwenhoek Journal of Microbiology and Serology , 1944-12-01, 10, 1: 15-16. (wikimedia.org)
  • Y. pestis was discovered in 1894 by Alexandre Yersin, a Swiss/French physician and bacteriologist from the Pasteur Institute, during an epidemic of the plague in Hong Kong. (wikipedia.org)
  • In 1943 and 1944, plague came back in several Mediterranean towns and ports and was considered as a serious danger for the Allied Forces. (nih.gov)
  • Yersinia pestis, the causative agent of plague, is a nonmotile, gram-negative coccobacillus that persists in the natural environment in sylvatic cycles. (cdc.gov)
  • The complex genomic diversity of Yersinia pestis on the long-term plague foci in Qinghai-Tibet plateau. (nih.gov)
  • citation needed] Several complete genome sequences are available for various strains and subspecies of Y. pestis: strain KIM (of biovar Y. p. medievalis), and strain CO92 (of biovar Y. p. orientalis, obtained from a clinical isolate in the United States). (wikipedia.org)
  • pFra codes for a phospholipase D that is important for the ability of Y. pestis to be transmitted by fleas. (wikipedia.org)
  • Detection of Rickettsia felis , Rickettsia typhi , Bartonella species, and Yersinia pestis in fleas (Siphonaptera) from Africa. (medscape.com)
  • Yersinia pestis biovar Microtus str. (up.ac.za)
  • Together, these plasmids, and a pathogenicity island called HPI, encode several proteins that cause the pathogenesis for which Y. pestis is famous. (wikipedia.org)
  • Many novel sRNAs were identified from Y. pestis grown in vitro and in the infected lungs of mice suggesting they play role in bacterial physiology or pathogenesis. (wikipedia.org)
  • Numerous antiphagocytic factors protect Y. pestis from human immune responses and allow reproduction and spread of the bacteria ( 6 ). (cdc.gov)
  • The Library's foundation collection , donated to the University by Mr Whipple in 1944, comprises approx. (cam.ac.uk)