• infect
  • Each phage can only infect a specific bacterial host, as it has to be able to link with special structures on the surface of the bacterial cell. (blogspot.com)
  • rivers
  • If I suggested that a cure for the cholera outbreak in Haiti could be found in the same rivers thought to be responsible for the outbreak in the first place, most people would consider me crazy. (blogspot.com)
  • known
  • But with lingering questions about phages, which are often dubbed viral dark matter because so little is known about their biology, their use in mainstream medicine still faces many hurdles. (braintalkcommunities.org)
  • made
  • However, they were abandoned for general use in the West for several reasons: Medical trials were carried out, but a basic lack of understanding of phages made these invalid. (wikipedia.org)
  • cycle
  • Finally, the infected cell bursts - releasing the new crop of phages and starting another cycle of infection and phage reproduction. (blogspot.com)
  • treat
  • The first therapeutic usage of phage was in 1919, to treat a child with severe dysentery. (openwetware.org)
  • Another phage preparation, Agriphage, a phage product that is commercially available from Omnilytics , is used primarily to treat bacterial damage of tomatoes and peppers, and has been recognized as being compatible with organic food production. (blogspot.com)
  • patients
  • Is it absurd that phage biocontrol products are accepted in the West for prevention or treatment of contamination in food, but not available to patients suffering from antibiotic-resistant infections? (blogspot.com)
  • cell
  • This can be accomplished by that by modifying phage to express endonucleases and holins, which are toxic to the cell (chopping DNA and making non-catastrophic disruptions to the cellular membrane)[ 3 ]. (openwetware.org)