Human8
- La base de données de référence de protéines humaines ( Human Protein Reference Database = HPRD ) est une base de données de protéines accessible via Internet. (wikipedia.org)
- Development of human protein reference database as an initial platform for approaching systems biology in humans », Genome Research, vol. 13, no 10, 2003, p. 2363-71 (PMID 14525934, PMCID 403728, DOI 10.1101/gr.1680803) Gandhi T.K.B. et al. (wikipedia.org)
- Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets », Nature Genetics, vol. 38, no 3, mars 2006, p. 285-293 (PMID 16501559, DOI 10.1038/ng1747) Mathivanan S. et al. (wikipedia.org)
- An evaluation of human protein-protein interaction data in the public domain », BMC Bioinformatics, vol. 2006, no 7, 2006, S19 (PMID 17254303, PMCID 1764475, DOI 10.1186/1471-2105-7-s5-s19) Mishra G. et al. (wikipedia.org)
- Human protein reference database-2006 update », Nucleic Acids Research, vol. 34, no Database issue, 2006, p. 411-414 (PMID 16381900, PMCID 1347503, DOI 10.1093/nar/gkj141) Mathivanan S. et al. (wikipedia.org)
- The V3 loop of the human immunodeficiency virus (HIV)-1 surface envelope glycoprotein gp120 is a sphingolipid-binding domain mediating the attachment of HIV-1 to plasma membrane microdomains (rafts). (amypore.com)
- Structure similarity searches with the combinatorial extension method revealed the presence of a V3-like domain in the human prion protein PrP and in the Alzheimer beta-amyloid peptide. (amypore.com)
- Solution Structure of the RBCC/TRIM B-box1 Domain of Human MID1: B-box with a RING 2006 et Solution Structure of the MID1 B-box2 CHC(D/C)C2H2 Zinc-binding Domain: Insights into an Evolutionarily Conserved RING Fold 2007 et Structure of the MID1 Tandem B-Boxes Reveals an Interaction Reminiscent of Intermolecular Ring Heterodimers 2008 . (vetopsy.fr)
Essential2
- HxuA/HxuB belongs to the so-called two-partner secretion systems (TPSs) that are characterized by a conserved N-terminal domain in the secreted protein which is essential for secretion. (univ-lille.fr)
- The dCtBP binding motif of Hairless is essential for the function of Hairless in vivo. (pasteur.fr)
Found2
- In each case, synthetic peptides derived from the predicted V3-like domain were found to interact with monomolecular films of galactosylceramide and sphingomyelin at the air-water interface. (amypore.com)
- They reveal that despite limited sequence identity, strong structural similarities are found between the β-helix motifs, consistent with the idea that the TPS domain plays a role not only in the interaction with the specific TpsB partners but also as the scaffold initiating progressive folding of the TpsA proteins at the bacterial surface. (univ-lille.fr)
Proteins1
- Moreover, biochemical studies have started to unravel the multiple direct molecular interactions between USH1 proteins. (medecinesciences.org)
Reveals2
- The structure reveals that HxuA301 folds into a β-helix domain with two extra-helical motifs, a four-stranded β-sheet and an N-terminal cap. (univ-lille.fr)
- La B-box de type 2 tourne alors de 90° par rapport à la B-box de type 1 ( Structure of the MID1 Tandem B-Boxes Reveals an Interaction Reminiscent of Intermolecular Ring Heterodimers 2008 ). (vetopsy.fr)
Activity2
- Haemophilus influenzae HxuA is a cell-surface protein with haem-haemopexin binding activity which is key to haem acquisition from haemopexin and thus is one of the potential sources of haem for this microorganism. (univ-lille.fr)
- Certains B-box de type 2 ne comporte qu'un seul atome de zinc chélaté par 2 cystéines et deux histidines comme XNF7 du xénope ( Enhancement of BRCA1 E3 Ubiquitin Ligase Activity through Direct Interaction with the BARD1 Protein 2002 ). (vetopsy.fr)
Structure1
- Here, the 1.5 Å resolution structure of the secretion domain of HxuA, HxuA301, is reported. (univ-lille.fr)
Contain1
- This screen yielded three ubiquitin-protein ligases, WWP1, WWP2, and AIP4, all of which belong to the HECT family and contain multiple WW domains. (timc.fr)
Contient2
- PhosphoMotif Finder contient un substrat kinase/phosphatase connu ainsi que des motifs de liaison extraits de la littérature publiée. (wikipedia.org)
- Le trimère de tri des protéines vacuolaire (VPS ou Vacuolar Protein Sorting) contient VPS35, VPS26A/VPS26B et VPS229, i.e. équivalent de Vps35, Vps26 et Vps29 de la levure ( Assembly and Solution Structure of the Core Retromer Protein Complex 2010 ). (vetopsy.fr)
Domaine3
- Nous avons également proposé un modèle cohérent des trois motifs glycine zippers individuels qui donnent leur nom au domaine (GlyZip)3 C-terminal des calcyanines. (sorbonne-universite.fr)
- Cependant, nous n'avons pu obtenir de modèle satisfaisant de l'assemblage des motifs glycine zipper (domaine (GlyZip)3), ni de leur interaction potentielle avec le domaine CoBaHMA, renforçant ainsi l'intérêt d'une étude expérimentale. (sorbonne-universite.fr)
- Au sein de ce complexe, Gag expose un résidu myristate amino-terminal et permet son interaction avec les bicouches lipidiques, stabilisée par l'interaction d'une région amino-terminale du domaine MA, chargée positivement (+ + +), avec les phospholipides membranaires. (inserm.fr)
Base3
- Adenovirus penton base protein is involved in virus internalization. (timc.fr)
- The first N-terminal xPPxY motif in the base protein sequence is indispensable for the interaction. (timc.fr)
- The binding parameters studied by surface plasmon resonance confirmed the interaction of base protein with three ubiquitin-protein ligases. (timc.fr)
Structure1
- Elle laisse le reste de la structure libre pour les engagements avec les membranes et pour les changements de conformation ( The retromer subunit Vps26 has an arrestin fold and binds Vps35 through its C-terminal domain 2006 ). (vetopsy.fr)