Benign Symmetric Lipomatosis

  • Madelung's Disease (also called Multiple Symmetrical Lipomatosis [MSL], Benign Symmetric Lipomatosis or Lanois-Bensaude Syndrome) is a metabolic condition characterized by the growth of fatty masses around the face, back of the head, neck, upper arms, abdomen, back and upper leg in a very specific pattern or distribution. (
  • The National Organization for Rare Disorders briefly describes this rare disorder (also known as Multiple Symmetrical Lipomatosis, Benign Symmetric Lipomatosis or Lanois-Bensaude Syndrome) and lists further reference information. (
  • Madelung's disease (also known as benign symmetric lipomatosis, the Launois-Bensaude syndrome, and multiple symmetric lipomatosis) is a rare disorder of unknown cause. (


  • Diffuse lipomatosis of the thyroid with amyloid deposition. (
  • Conclusion: To our best knowledge, this patient represents the first reported case of diffuse lipomatosis of the thyroid gland causing goitre in a patient with AA amyloidosis. (


  • [ 1 ] They suggested that the man had a previously unreported neurocutaneous syndrome, which they termed encephalocraniocutaneous lipomatosis. (
  • Encephalocraniocutaneous lipomatosis has also become known under the term Fishman syndrome. (
  • In 2004, Cultrera et al described a female infant that showed significant overlap of encephalocraniocutaneous lipomatosis with oculocerebrocutaneous Delleman syndrome. (
  • Encephalocraniocutaneous lipomatosis: a rare neurocutaneous syndrome. (


  • Encephalocraniocutaneous lipomatosis (ECCL) is a rare, congenital, neurocutaneous disorder with unilateral lipomatous cutaneous neoplasms devoid of hair and ipsilateral ophthalmologic and neurologic malformations. (


  • Ayer RE, Zouros A. Encephalocraniocutaneous lipomatosis: a review of its clinical pathology and neurosurgical indications. (


  • To the editor: The interesting case of corticosteroid-induced epidural lipomatosis reported by Drs. Butcher and Sahn in the January 1979 issue (1) is very similar to that reported in a renal transplant recipient (2). (
  • Hauber K, Warmuth-Metz M, Rose C, Brocker EB, Hamm H. Encephalocraniocutaneous lipomatosis: a case with unilateral odontomas and review of the literature. (


  • Describes the form of Multiple Symmetric Lipomatosis (MSL) characterized by a collar of fat around the neck. (