OrganismsDiseasesChemicals and Drugs
Erythema NodosumLeprosy, LepromatousErythemaLeprostatic AgentsAscophyllumLeprosyLeprosy, BorderlineSarcoidosisBehcet SyndromeLeprosy, MultibacillarySerositisUterine Cervical ErosionPyoderma GangrenosumTuberculosis, CutaneousMycobacterium lepraePeriarthritisScleral DiseasesThalidomideSkin DiseasesSeaweedPhaeophyta
LeprosumLeprosyInduratumSigns of erythema nodosumCause of erythema nodosumLesionsHypersensitivity reactionNodulesSHINSInflammatoryPrognosisTuberculosisBumpsSymptomsElevatum diutinumNodularSarcoidosisDiagnosisYersiniaInfectionScalpSignificanceInfectionsTenderCommonAcuteSubcutaneousSkinFeverClinicalOccurOutlookPregnancyPatientsTreatmentDoctorsIncludeConditionCasesExaminationConditions
Leprosum14
  • The treatment of erythema nodosum leprosum with B.663. (nih.gov)
  • The effect of stopping dapsone treatment for two months and then restarting it in full dosage in patients with moderately severe erythema nodosum leprosum. (nih.gov)
  • Histoid leprosy with erythema nodosum leprosum]. (nih.gov)
  • Interventions for erythema nodosum leprosum. (nih.gov)
  • Rationale use of Thalidomide in erythema nodosum leprosum - A non-systematic critical analysis of published case reports. (nih.gov)
  • THALOMID is indicated for the acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL). (nih.gov)
  • A Case of Lepromatous Leprosy With Erythema Nodosum Leprosum. (bvsalud.org)
  • Erythema nodosum leprosum is an immunologic reaction that occurs in patients with lepromatous leprosy . (bvsalud.org)
  • Given the patient 's clinical, laboratory , and histological findings, a diagnosis of lepromatous leprosy with a type 2 erythema nodosum leprosum reaction was established. (bvsalud.org)
  • Early recognition and treatment of leprosy are crucial to preventing chronic and disabling complications , especially in instances of systemic inflammatory responses such as erythema nodosum leprosum. (bvsalud.org)
  • Background : Erythema Nodosum Leprosum (ENL) recurrent is a serious complication of leprosy immunology, that cause the inflammation of the skin, nerves and other organs. (biomedscidirect.com)
  • In 1965, researchers first reported that thalidomide's anti-inflammatory effect could ease erythema nodosum leprosum (ENL), a painful condition in leprosy patients. (the-scientist.com)
  • Interestingly, at the time Thalomid was approved only for treatment of a side effect of leprosy called erythema nodosum leprosum (ENL). (foxbusiness.com)
  • Leprosum The treatment of erythema nodosum leprosum (ENL) reactions (type 2 reactions) depends on the severity of symptoms. (antiinfectivemeds.com)
Leprosy1
  • Medications associated with EN include: Omeprazole Sulfonamides Penicillins Bromides Hepatitis B vaccination Cancers associated with EN include: Non-Hodgkin's lymphoma (NHL) Carcinoid tumours Pancreatic cancer EN may also be due to excessive antibody production in lepromatous leprosy leading to deposition of immune complexes. (wikipedia.org)
Induratum1
  • Erythema nodosum and erythema induratum (nodular vasculitis): diagnosis and management. (medscape.com)
Signs of erythema nodosum2
  • The first signs of erythema nodosum are often flu-like symptoms such as a fever, cough, malaise, and aching joints. (wikipedia.org)
  • Low-grade fever and unexplained exhaustion are also signs of erythema nodosum. (facty.com)
Cause of erythema nodosum3
  • Additional evaluation should be performed to determine the underlying cause of erythema nodosum. (wikipedia.org)
  • In about half of cases, the exact cause of erythema nodosum is unknown. (medlineplus.gov)
  • Even though infections are the most common cause of erythema nodosum (EN), only certain microorganisms take the great interest such as streptococci in knowledge. (deu.edu.tr)
Lesions5
  • Erythema nodosum lesion in a person with light skin and tuberculosis A single lesion of erythema nodosum Several lesions of erythema nodosum in an individual with dark skin EN is associated with a wide variety of conditions. (wikipedia.org)
  • Erythema nodosum is a condition that forms painful lesions of bluish-red nodules which can resemble bruising on the skin in the shin area. (news-medical.net)
  • As some cases manifested erythema nodosum (EN)-like lesions, 14 specimens of EN were reviewed to identify features for differential diagnosis. (qxmd.com)
  • LDS may manifest as EN-like lesions. (qxmd.com)
  • After the medical provider has identified the lesions as erythema nodosum, you may discuss potential causes. (facty.com)
Hypersensitivity reaction2
  • Erythema nodosum is probably a delayed hypersensitivity reaction to a variety of antigens. (wikipedia.org)
  • Erythema Nodosum is a hypersensitivity reaction causing a localized inflammatory infiltrate that. (hpathy.com)
Nodules4
  • Erythema nodosum (EN) is an inflammatory condition characterized by inflammation of the fat cells under the skin, resulting in tender red nodules or lumps that are usually seen on both shins. (wikipedia.org)
  • Erythema nodosum is characterised by 1-2-inch (25-51 mm) nodules (rounded lumps) below the skin surface, usually on the shins. (wikipedia.org)
  • The ESR is initially very high and falls as the nodules of erythema nodosum. (wikipedia.org)
  • Â Erythema nodosum (EN) is an inflammation of the skin fat typically presenting as reddish tender nodules on the lower legs and disappearing in few weeks. (cdc.gov)
SHINS3
  • Classic presentation of erythema nodosum with nodular red swellings over the shins. (medscape.com)
  • Erythema nodosum is most common on the front of the shins. (medlineplus.gov)
  • Erythema nodosum often looks like painful lumps or bruises, generally on the shins. (facty.com)
Inflammatory6
  • Significance of erythema nodosum and pyoderma gangrenosum in inflammatory bowel diseases: a cohort study of 2402 patients. (medscape.com)
  • Erythema nodosum is an inflammatory disorder. (medlineplus.gov)
  • Sarcoid, an inflammatory condition of unknown cause that can affect almost any organ, and inflammatory bowel disease (cause also unknown) may both also be associated with erythema nodosum . (diagnose-me.com)
  • Erythema nodosum is an inflammatory reaction in the layer of fat under your skin. (msdmanuals.com)
  • Erythema nodosum can be treated with medicines such as oral steroids, immunosuppressants, nonsteroidal anti-inflammatory drugs (NSAIDs). (news-medical.net)
  • Erythema nodosum is an inflammatory disorder involving the deep dermis layer of skin and subcutaneous fat septa that underlies the skin. (glutenfreeworks.com)
Prognosis1
  • The long-term prognosis of the condition is good because erythema nodosum does not affect the internal organs. (facty.com)
Tuberculosis5
  • Infections associated with EN include: Streptococcal infection which, in children, is by far the most common precipitant Primary infection of tuberculosis Mycoplasma pneumoniae Histoplasma capsulatum Yersinia Lymphogranuloma venereum (LGV), caused by the bacteria Chlamydia trachomatis Epstein-Barr virus Coccidioides immitis (Valley fever) Cat scratch disease Autoimmune disorders associated with EN include: Inflammatory bowel disease (IBD): about 15% of patients develop erythema nodosum. (wikipedia.org)
  • Mert A, Ozaras R, Tabak F, Ozturk R. Primary tuberculosis cases presenting with erythema nodosum. (medscape.com)
  • Chlamydia, tuberculosis , and other bacterial and fungal infections may also be associated with erythema nodosum, but fungal infections involving only the skin, such as athlete's foot , are not. (diagnose-me.com)
  • Erythema nodosum is not an allergic reaction to these conditions or drugs, nor does it contain any infectious organisms such as tuberculosis bacilli or strep germs. (diagnose-me.com)
  • Our data confirm the predominance of streptococcal infections among the etiologic factors while also considering tuberculosis as a causative factor among children with EN in Turkey. (turkishjournalpediatrics.org)
Bumps1
  • Doctors can usually tell you have erythema nodosum by looking at the bumps on your skin. (msdmanuals.com)
Symptoms3
  • Contact your provider if you develop symptoms of erythema nodosum. (medlineplus.gov)
  • What are the symptoms of erythema nodosum? (msdmanuals.com)
  • There are various symptoms and treatments of erythema nodosum, but always make sure to follow up with your doctor regarding the best way to treat your condition. (facty.com)
Elevatum diutinum2
  • What Is Erythema Elevatum Diutinum? (glutenfreeworks.com)
  • Erythema elevatum diutinum is a rare leucocytoclastic vasculitis thought to be caused by an immune response that is characterized by inflammation, a rash, and scarring of small blood vessels of the skin. (glutenfreeworks.com)
Nodular3
  • Less common variants of erythema nodosum include: Ulcerating forms, seen in Crohn's disease Erythema contusiforme, when a subcutaneous hemorrhage (bleeding under the skin) occurs with an erythema nodosum lesion, causing the lesion to look like a contusion (bruise) Erythema nodosum migrans (also known as subacute nodular migratory panniculitis), a rare form of chronic erythema nodosum characterized by asymmetrical nodules that are mildly tender and migrate over time. (wikipedia.org)
  • Erythema nodosum is also known as subacute nodular migratory panniculitis. (facty.com)
  • EN is the most frequent clinical form of acute nodular panniculitis and it is considered an epiphenomenon relative to various infectious and non-infectious stimuli. (unicatt.it)
Sarcoidosis1
Diagnosis3
  • Lipodermatosclerosis: a clinicopathologic study of 17 cases and differential diagnosis from erythema nodosum. (qxmd.com)
  • Therefore LDS should be included in the differential diagnosis of EN. (qxmd.com)
  • You may also need a biopsy to examine the affected skin and fully confirm the diagnosis of erythema nodosum. (facty.com)
Yersinia1
  • Erythema nodosum and exudative pharyngitis are suggestive of Yersinia infection. (medscape.com)
Infection2
  • If your erythema nodosum is caused by an infection, doctors will treat the infection. (msdmanuals.com)
  • In older youngsters, joint pain or a red skin lump (erythema nodosum) on the lower legs may develop after the infection itself has gone away. (healthychildren.org)
Scalp1
  • The association of EN with dermatophytosis of the scalp is infrequent, with only 15 cases reported in the Literature. (unicatt.it)
Significance1
  • The real significance of erythema nodosum lies in the possibility of a serious underlying disease. (diagnose-me.com)
Infections4
  • Finally, all kinds of infections, ranging from the common, such as strep throat, to the uncommon, such as coccidioidomycosis (a fungal disease mostly seen in the southwestern U.S.), may be associated with erythema nodosum. (diagnose-me.com)
  • Known causes of EN include infections, drugs, and other general diseases. (cdc.gov)
  • Our aim was to examine the frequency and type of infections in EN, to determine the characteristics of patients with an infectious etiology, and to discuss the role of these microbes in EN pathology in the context of their interactions with humans. (deu.edu.tr)
  • Firstly, transient conditions such as vasculitis, post-vaccinal arthritis or erythema nodosum might be due to the deposition of immune complexes containing viral antigen and anti-hepatitis B antibodies, as seen in some hepatitis B infections, or to hypersensitivity to components of the vaccine like thimesoral or yeast proteins. (bmj.com)
Tender1
  • Erythema nodosum usually presents as reddish, painful, tender lumps about the size of a dime or quarter, situated on the front of the legs, below the knees. (facty.com)
Common3
  • How Common is Erythema Nodosum? (facty.com)
  • Erythema nodosum is not a common disease. (facty.com)
  • We will discuss the common causes of erythema nodosum. (afaig.com)
Acute2
  • Sullivan R, Clowers-Webb H, Davis MD. Erythema nodosum: a presenting sign of acute myelogenous leukemia. (medscape.com)
  • Differentiating the acute LDS from the early EN is more difficult. (qxmd.com)
Subcutaneous1
  • Wilk M, Zelger BG, Hayani K, Zelger B. Erythema Nodosum, Early Stage-A Subcutaneous Variant of Leukocytoclastic Vasculitis? (medscape.com)
Skin2
  • Erythema annulare centrifugum (EAC) is a skin condition that causes red spots to form on the feet. (afaig.com)
  • Erythema nodosum (EN), which is a rare skin manifestation among children, is precipitated by a range of infectious and non-infectious diseases. (turkishjournalpediatrics.org)
Fever1
Clinical3
  • Erythema nodosum is a fairly uncommon, but distinctive, clinical syndrome. (diagnose-me.com)
  • The cause of this EN cluster could not be found despite an extensive search for known causative agents based on patient interviews, clinical presentation, laboratory tests (serology) and chest radiographs. (cdc.gov)
  • The purpose of this study was to evaluate the epidemiology, etiology, clinical manifestations and course of EN among children. (turkishjournalpediatrics.org)
Occur2
  • Sometimes, erythema nodosum may occur during pregnancy. (medlineplus.gov)
  • Even though erythema nodosum can occur at any age, it is prevalent in people between the ages of 20 and 30 years. (facty.com)
Outlook1
  • What is the Outlook for People with Erythema Nodosum? (facty.com)
Pregnancy1
  • Is Erythema Nodosum Connected to Pregnancy? (facty.com)
Patients6
  • There is an association with the HLA-B27 histocompatibility antigen, which is present in 65% of patients with erythema nodosum. (wikipedia.org)
  • Erythema nodosum and Sweet's syndrome in patients with glandular tularemia. (nih.gov)
  • Twenty-five patients from a rural community in New Mexico were diagnosed with EN during the winter 2007âˆ'2008. (cdc.gov)
  • Charts of 81 patients with EN who were seen between 2003 and 2017 were retrospectively reviewed. (deu.edu.tr)
  • Unit of Infectious Diseases, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey Cengiz AB, Kara A, Kanra G, Seçmeer G, Ceyhan M. Erythema nodosum in childhood: evaluation of ten patients. (turkishjournalpediatrics.org)
  • A total of 10 patients diagnosed with EN between January 2000 and March 2004 at Hacettepe University İhsan Doğramacı Children's Hospital, Pediatric Infectious Diseases Outpatient Clinic, were studied retrospectively. (turkishjournalpediatrics.org)
Treatment2
  • Compression stockings as an effective treatment for erythema nodosum: Case series. (medscape.com)
  • Since the erythema itself is not dangerous and heals without treatment, doctors will spend most of their time and effort trying to rule out an underlying cause. (diagnose-me.com)
Doctors2
Include1
  • Drugs that can cause erythema nodosum include penicillin (in all its forms), sulfa drugs, and oral contraceptives. (diagnose-me.com)
Condition1
  • Many people suffer from this condition, which is known as erythema nodosum. (afaig.com)
Cases3
Examination1
  • Erythema nodosum (EN) was confirmed by histological examination of a nodule and then we combined therapy with 1 mg Kg(-1) day(-1) of prednisone. (unicatt.it)
Conditions1