• inflammatory
  • To address these discrepancies, we assessed the differential role of IL-17 pathway in two models of fungal sepsis: intravenous infection with live Candida albicans , in which fungal growth is the main cause of mortality, and zymosan-induced multiple organ failure in which the inflammatory pathology drives the mortality. (biomedcentral.com)
  • cells
  • Zymosan A increased TNF-alpha production in RAW264.7 cells in a time and concentration dependent pattern with the optimal time and concentration occurring at 23 hr and 100 ug/mL zymosan A, respectively. (cdc.gov)
  • A gel shift assay was used to examine the DNA-binding activity of NFkB in the zymosan A- treated cells. (cdc.gov)