• Zeranol (α-zearalanol) is a metabolite of the mycoestrogen zearalenone, and is used as a growth promoter of livestock due to its strong estrogenic activity. (elsevierpure.com)
  • Zeranol (Zer) is a semi-synthetic derivative of Zearalenone, a myco-estrogen produced by Fusarium fungi, that is used in livestock to enhance meat production. (rutgers.edu)
  • Since 1985, the analysis of mycotoxins - ochratoxin A, zeranol and zearalenone has been part of the routine. (veinst.hr)
  • Zeranol is approved for use as a growth promoter in livestock, including beef cattle, under the brand name Ralgro (by Merck Animal Health) in the United States. (wikipedia.org)
  • Currently, at this printing, implants with active ingredients of estradiol and progesterone, and zeranol have been given FDA approval for use on potential replacement heifer calves. (steerplanet.com)
  • Both the 36 mg zeranol implants and the 10 mg estradiol - 100 mg progesterone type implants are examined. (steerplanet.com)
  • Average daily gain responses of approximately .1 pound per day can be expected with the zeranol and estradiol-progesterone implants in steer calves. (steerplanet.com)
  • Tripanichkul estradiol, progesterone, and zeranol are similarly to dangerous drugs. (surgicalproductsmag.com)
  • Zeranol is a non‑steroidal agent with potent estrogenic activity, which is widely used as a growth promoter for cattle in certain countries. (spandidos-publications.com)
  • Zeranol has approximately 30-33% the estrogenic effect of Estradiol. (thecattlesite.com)
  • Although zeranol may increase cancer cell proliferation in already existing breast cancer, dietary exposure from the use of zeranol-containing implants in cattle is insignificant. (wikipedia.org)
  • The present study hypothesized that aromatase expression and activity may be elevated by low dose zeranol exposure, providing a source of estrogens that may stimulate cell proliferation. (spandidos-publications.com)
  • The authors conclude that workers have a considerable exposure to zeranol which poses a potential health risk. (cdc.gov)
  • He tested positive for having taken the banned anabolic agent Zeranol, so today was handed an 8-year ban by the Independent Doping Tribunal Panel. (rugbydump.com)
  • Si les hormones androgènes sont connues pour leur rôle essentiel chez l'homme, celles-ci sont également présentes en plus faible quantité chez la femme. (danglar.com)
  • At low concentrations, zeranol accelerated the growth of ER-positive MCF-7 and KPL-1 human breast carcinoma cells, but did not affect the growth of ER-negative MDA-MB-231 cells. (elsevierpure.com)
  • At high concentrations, zeranol suppressed the growth of both ER-positive and -negative human breast carcinoma cells. (elsevierpure.com)
  • Thus, zeranol exerted dose-dependent biphasic effects on ER-positive human breast carcinoma cells, accelerating cell growth at low concentrations and inducing apoptosis at high concentrations. (elsevierpure.com)
  • Wipe samples showed zeranol concentrations up to 14mg per sample. (cdc.gov)
  • The effects of zeranol on cell proliferation were measured using the MTS assay, aromatase expression levels were determined by immunocytochemical staining and reverse transcription‑polymerase chain reaction, and aromatase enzyme activity and estrogen production were analyzed using corresponding assay kits. (spandidos-publications.com)
  • The results demonstrated that low dose zeranol (2‑50 nM) was able to significantly promote cell proliferation, aromatase mRNA expression, aromatase activity and estrogen production in primary cultured human breast preadipocytes, thus suggesting that zeranol may act as an aromatase activator. (spandidos-publications.com)
  • The Economist has established that the detection of Zeranol in one of the urine samples collected from two weaners led to the temporary closure of the feedlot. (economist.com.na)
  • Shedding light on the quarantine, Meatco's spokesperson Rosa Thobias said, "On 31 March 2016, we received the result of a [urine] sample taken on 25 June 2015, that indicated the presence of Zeranol. (economist.com.na)
  • The most common hormone ear implants contain zeranol or a mixture of trenbalone and estradiol. (foodfacts.org.za)
  • A previous report demonstrated that zeranol is comparable to natural 17β-estradiol (E2) and the synthetic estrogen diethylstilbestrol in its ability to transform MCF-10A normal human breast epithelial cells to a pre-cancerous phenotype in vitro ( 17 ). (spandidos-publications.com)
  • In the present study, we investigated the effects of zeranol on the growth of estrogen receptor (ER)-positive and -negative human breast carcinoma cells in vitro, and the molecules involved. (elsevierpure.com)
  • Zeranol according to Meatco, has been listed as a banned substance and its use has been prohibited by the both the European Union and the Namibian Government, the meat processor briefly explained. (economist.com.na)
  • Zeranol is a non-steroidal estrogen agonist that is approved for use as a growth promoter in livestock, including beef cattle, in various countries. (spandidos-publications.com)
  • Summary of trials where heifer calves were implanted once with Zeranol at 1 to 3 months of age. (steerplanet.com)
  • The findings of the present study suggest that zeranol promotes breast cancer cell growth by stimulating aromatase activation and increasing estrogen biosynthesis in adipose tissue. (spandidos-publications.com)
  • The acceleration of ER-positive cell growth by low-dose zeranol involved the down-regulation of p21 Cip1 (a cyclin-dependent kinase inhibitor), which resulted in cell cycle progression. (elsevierpure.com)
  • Environmental and breathing zone samples were analyzed for zeranol (26538443) at Manufacturing Chemists, Incorporated (SIC-2879, SIC- requested by the State Industrial Hygiene Compliance Section to assist in evaluating the occurrence of breast symptoms, weight gain, and gynecomastia in employees and their children. (cdc.gov)
  • Blood samples were analyzed for zeranol metabolites. (cdc.gov)
  • No zeranol metabolites were found in blood samples. (cdc.gov)
  • Zeranol may be found as a contaminant in fungus-infected crops. (wikipedia.org)
  • There is no current Federal standard for zeranol. (cdc.gov)
  • Of the two animals sampled only one tested positive for Zeranol. (economist.com.na)
  • The Zeranol positive case was his third positive dope test during his playing career within a 10-year period, however the player's first positive case was ruled a No Fault decision and he then received a reprimand," Saids said. (rugbydump.com)
  • They are three of course happening endocrines which are estradiol, Lipo-Lutin and testosterone and three synthetically produced endocrines which are zeranol, trenbolone and melengestrol. (lyceecharlesdegaulle.eu)
  • They are three naturally occurring hormones which are estradiol, progesterone and testosterone and three synthetically produced hormones which are zeranol, trenbolone and melengestrol. (essaymonster.net)
  • A female endocrine zeranol, 17 beta-estradiol and melengestrol acecate ( MGA ) are normally used to engraft or shoot into cattles for industry utilizations. (lyceecharlesdegaulle.eu)
  • A female hormone zeranol, 17 beta-estradiol and melengestrol acecate (MGA) are commonly used to implant or inject into cows for industry uses. (essaymonster.net)
  • Radioimmunoassay of the anabolic agent zeranol II. (zju.edu.cn)
  • There is any doubt testing, namely estradiol E2, estradiol benzoate, zeranol, trenbolone acetate for sample processing, published protocols were combined considering unconjugated, glucuronic acid-, sulfo- and alkaline-labile conjugated steroid metabolites. (bootb.com)
  • Estrogens consist either of the naturally occurring estradiol-17β, a synthetic version called estradiol benzoate or an estrogen-like compound called zeranol. (beefweb.com)
  • Andarine and ostarine), tibolone, zeranol and zilpaterol. (ourcowsva.com)
  • Blood samples were analyzed for zeranol metabolites. (cdc.gov)
  • No zeranol metabolites were found in blood samples. (cdc.gov)
  • With widespread human dietary exposure and growing experimental evidence of endocrine-disrupting properties, a comprehensive review of the impact of ZEN, zeranol, and their metabolites on the female reproductive system is warranted. (nih.gov)
  • The objective of this systematic review was to summarize the in vitro, in vivo, and epidemiological literature and evaluate the potential impact of ZEN, zeranol, and their metabolites (commonly referred to as mycoestrogens) on female reproductive outcomes. (nih.gov)
  • Experimental research suggests that ZEN and zeranol disrupt the endocrine and reproductive systems, leading to infertility, polycystic ovarian syndrome-like phenotypes, pregnancy loss, and low birth weight. (nih.gov)
  • El cardarine (también conocido como endurobol o gw- 501516) es una sustancia que fue desarrollada en los años 90 para prevenir y curar la formación de You must also remember to train according to the intake of ostarine, cardarine que es. (riinalaerre.com)
  • Although zeranol may increase cancer cell proliferation in already existing breast cancer, dietary exposure from the use of zeranol-containing implants in cattle is insignificant. (wikipedia.org)
  • The Randox Food Diagnostics Zeranol ELISA test kit offers excellent cross reactivity screening zearalone derivative growth promoter residues in meat. (randox.com)
  • A high affinity polyclonal antibody-based enzyme linked immunosorbent assay (ELISA) was developed for the quantification of zeranol in bovine urine . (zju.edu.cn)
  • Thirty-six bovine urine samples spiked with zeranol (ranging from 0.2 to 10 μg/ml) were detected by the ELISA and liquid chromatography (LC) method, and good correlations were obtained between the two methods ( R 2 =0.9643). (zju.edu.cn)
  • We conclude that this improved ELISA is suitable tool for a mass zeranol screening and can be an alternative for the conventional LC method for zeranol in bovine urine . (zju.edu.cn)
  • Development and evaluation of immunoassay for zeranol in bovine urine[J]. Journal of Zhejiang University Science B, 2007, 8(12): 900-905. (zju.edu.cn)
  • Validation of screening method for residues of diethylstilbestrol, dienestrol, hexestrol, and zeranol in bovine urine using immunoaffinity chromatography and gas chromatography/mass spectrometry. (zju.edu.cn)
  • Zeranol: a review of the metabolism, toxicology, and analytical methods for detection of tissue residues. (zju.edu.cn)
  • There is no current Federal standard for zeranol. (cdc.gov)
  • Zeranol is a semi-synthetic product derived from the naturally occurring mycotoxin zeralenone. (randox.com)
  • Heidenhain Zeranol, https://www.adeptum.de/adeptum-alternative-zu-proscar-pflanzlich an dysphony tilidine, grated anthropoidal foregoing loners Useful Site outside a illuminates. (adeptum.de)