• cytoplasm
  • Consistent with this, we have demonstrated previously by confocal microscopy that uncoated virus cores within the cytoplasm lack the IMV surface protein D8L, and we show here that intracellular cores lack the surface protein coat and lipid membrane. (ox.ac.uk)
  • vesicular
  • The cytopathogenicity of vesicular stomatitis virus (VSV) has been attributed mainly to the host shut-off activity of the viral matrix (M) protein, which inhibits both nuclear transcription and nucleocytoplasmic RNA transport, thereby effectively suppressing the synthesis of type I interferon (IFN). (microbiologyresearch.org)
  • Lassa virus (Arenaviridae) Lymphocytic choriomeningitis virus (Arenaviridae) Hantavirus (Bunyaviridae) Marburg Virus (Filoviridae) Ebola virus (Filoviridae) Influenza (Orthomyxoviridae) Measles (Paramyxoviridae) Mumps virus (Paramyxoviridae) Human respiratory syncytial virus (Paramyxoviridae) Parainfluenza (Paramyxoviridae) Rabies (Rhabdoviridae) Vesicular stomatitis virus (Rhabdoviridae) The genome for negative-stranded RNA virus (NSV) consists of one to several single-stranded RNAs, which are assembled into complexes. (wikipedia.org)
  • infectious
  • Vaccinia virus (VV) morphogenesis commences with the formation of lipid crescents that grow into spherical immature virus (IV) and then infectious intracellular mature virus (IMV) particles. (ox.ac.uk)
  • Therefore, the purified RNA of a negative sense virus is not infectious by itself, as it needs to be converted to a positive sense RNA for replication. (wikipedia.org)
  • Cells
  • Examination of thin sections of Epon-embedded, VV-infected cells by use of a high-angular-tilt series of single sections, serial-section analysis, and high-resolution digital-image analysis detected only a single, 5-nm-thick lipid bilayer in virus crescents, IV, and IMV particles that is covered by a 8-nm-thick protein coat. (ox.ac.uk)
  • The complexity of negative-sense single-stranded RNA viruses carries into its ability to suppress the innate immune response of the cells it infects and the construction of a capsid, which is unique to the varying classifications of negative-sense single-stranded RNA viruses. (wikipedia.org)
  • single
  • A negative-sense single-stranded RNA virus (or (-)ssRNA virus) is a virus that uses negative sense, single-stranded RNA as its genetic material. (wikipedia.org)
  • Single stranded RNA viruses are classified as positive or negative depending on the sense or polarity of the RNA. (wikipedia.org)
  • In addition, negative-sense single-stranded RNA viruses have complex genomic sequences, cell cycles, and replication habits that use various protein complexes to arrange in specific conformations and carry out necessary processes for survival and reproduction of their genomic sequences. (wikipedia.org)