• Pharmacologic therapy includes anticoagulants, positive inotropic agents, and vasodilators. (medscape.com)
  • Currently, no evidence shows the use of prostanoids or their analogues as pulmonary vasodilators and sole therapeutic agents for the treatment of PPHN in neonates (age 28 days or less). (cochrane.org)
  • Other pulmonary vasodilators are used during the perioperative period as well as for long-term treatment. (acc.org)
  • Epoprostenol (prostacyclin), a naturally occurring prostaglandin, is a potent vasodilator and inhibitor of platelet aggregation. (medscape.com)
  • Apelin is a novel vasodilator peptide and the most potent inotropic agent discovered to date. (ed.ac.uk)
  • A potent vasodilator agent that increases peripheral blood flow. (curehunter.com)
  • Minoxidil A potent direct-acting peripheral vasodilator (VASODILATOR AGENTS) that reduces peripheral resistance and produces a fall in BLOOD PRESSURE. (scitoys.com)
  • Both vasoconstrictor and vasodilator neurohormones are stimulated and provide new therapeutic opportunities. (duke.edu)
  • These agents are useful to remove fluid and reduce preload and afterload in the treatment of heart failure. (medscape.com)
  • Clonidine hydrochloride USP tablets may be employed alone or concomitantly with other antihypertensive agents. (prescriptiondrugs.com)
  • With the advent of antihypertensive agents, the incidence of hypertensive emergencies in the United States has declined from 7% to approximately 1% of patients with hypertension. (medscape.com)
  • Details of antihypertensive drug therapy and compliance, intake of over-the-counter (OTC) preparations such as sympathomimetic agents, and use of illicit drugs such as cocaine are important elements of the medication history. (medscape.com)
  • The use of an oral inotropic agent is advocated in patients with right ventricular dysfunction that is associated with IPAH. (medscape.com)
  • Dipyridamole, a non-nitrate coronary vasodilator that also inhibits platelet aggregation, is combined with other anticoagulant drugs, such as warfarin, to prevent thrombosis in patients with valvular or vascular disorders. (pharmacycode.com)
  • An agent that causes an increase in the expansion of a bronchus or bronchial tubes. (ebi.ac.uk)
  • The positive inotropic and negative chronotropic effects of these agents are useful in the setting of left or right heart failure. (medscape.com)
  • These agents are also indicated to reduce the risk of hospitalization for heart failure in patients with type 2 diabetes mellitus who with either established cardiovascular disease or multiple cardiovascular risk factors. (medscape.com)
  • A piperazine derivative, PHOSPHODIESTERASE 5 INHIBITOR and VASODILATOR AGENT that is used as a UROLOGICAL AGENT in the treatment of ERECTILE DYSFUNCTION . (online-medical-dictionary.org)
  • Dipyridamole is also used in myocardial perfusion imaging, as an antiplatelet agent, and in combination with aspirin for stroke prophylaxis. (pharmacycode.com)
  • Vasodilator stress agents for myocardial perfusion imaging. (qxmd.com)
  • The use of vasodilators to counteract vasoconstriction in IPAH is based on both theory and on pathologic studies that implicate medial hypertrophy and vessel constriction in the pathogenesis of idiopathic pulmonary artery hypertension. (medscape.com)
  • If a pharmacologic stress test with a vasodilator such as adenosine or dipyridamole is to be performed, the patient should abstain from medications containing methylxanthines and beverages, food (such as chocolate), and medications containing caffeine for 12 h ( 2 ) to 24 h ( 3 , 4 ). (snmjournals.org)
  • Drugs reported to have triggered rosacea symptoms in some patients include topical steroids and oral vasodilators, ACE inhibitors and a cholesterol-lowering agent. (rosacea.org)
  • Epoprostenol is a strong vasodilator of all vascular beds. (medscape.com)
  • In both patients these lesions receded during the course of therapy with a selective arteriolar vasodilator, nifedipine.These observations are discussed in relation to the possible pathogenesis of the retinopathy seen in patientswith sickle cell anemia. (researchwithrutgers.com)
  • These agents competitively bind to endothelin-1 (ET-1) receptors ET A and ET B in endothelium and vascular smooth muscle, inhibiting vessel constriction and elevation of blood pressure. (medscape.com)
  • Maximal vasodilator capacity was examined by measuring minimal vascular resistance during peak reactive hyperemia after release from 10 minutes of arterial occlusion. (elsevierpure.com)
  • Clonidine hydrochloride USP is a centrally acting alpha-agonist hypotensive agent available as tablets for oral administration in three dosage strengths: 0.1 mg, 0.2 mg and 0.3 mg. (prescriptiondrugs.com)
  • to test this approach in patients undergoing vasodilator stress tests with MDCT imaging in combination with the new vasodilator stress agent Regadenoson. (drugpatentwatch.com)
  • Particular features of these procedures include hemostasis of extended surfaces and wide-awake, conscious patients, and a combination of anesthetic agents and local vasoconstrictors is needed. (intechopen.com)
  • We examined maximal vasodilator capacity of forearm resistance vessels in 23 normotensive young men (mean blood pressure 94 ± 0.4 mm Hg, mean ± SE) with hypertensive relatives (age 24 ± 0.1 years) and in 17 normotensive subjects (mean blood pressure 85 ± 0.4 mm Hg) with no family history of hypertension (age 24 ± 0.1 years). (elsevierpure.com)
  • Vasodilator therapy has been an important advance: combination hydralazine and nitrate therapy was initially shown to be efficacious in improving survival, and more recently, angiotensin-converting enzyme (ACE) inhibitors, in the form of enalapril, have shown incremental benefit on survival over this combination. (duke.edu)
  • Agents for hypertensive emergencies are given parenterally as it is critical to reduce the blood pressure immediately because at that stage it could be life threatening. (drugs.com)
  • Generally, agents used in hypertensive emergencies are vasodilators, which widen blood vessels and reduce blood pressure. (drugs.com)
  • If tachycardia is excessive, it may be necessary to use a beta-blocking agent concomitantly. (pharmacycode.com)
  • When RV failure occurs following LVAD implantation, the mainstay of treatment is inotropic and pulmonary vasodilator support while volume status is optimized. (acc.org)
  • [2] The development of pharmacological agents (antibiotics, vasodilators, antioxidant, and Vitamins) has enhanced the healing of acute as well as chronic wounds. (esamskriti.com)
  • Phenoxybenzamine is a long-acting, adrenergic, alpha-receptor blocking agent which can produce and maintain "chemical sympathectomy" by oral administration. (pharmacycode.com)
  • Co-administration with Other Vasodilators or Negative Chronotropic Agents: Use with caution due to additive pharmacodynamic effects. (nih.gov)
  • Although, on balance, the weight of evidence concerning the long-term efficacy of inotropic agents has been disappointing, especially as it relates to their unfavorable effects on survival, recent information on vesnarinone, an agent with a complex and diversified mechanism of action, suggests that with appropriate doses, improved symptoms and survival are possible. (duke.edu)
  • We confirmed the previous findings that increasing metabolic vasodilator stimulus by performing intermittent handgrip exercise during 10 minutes of arterial occlusion did not augment peak dilation. (elsevierpure.com)
  • A combination of anesthetic agents and local vasoconstrictors is needed. (intechopen.com)
  • Caffeine and methylxanthines block the adenosine receptors on arterial smooth muscle cells, thus limiting the effectiveness of these vasodilator agents ( 4 ). (snmjournals.org)
  • In animal studies, captopril did not alter the pressor responses to a number of other agents, including angiotensin II and norepinephrine, indicating specificity of action. (nih.gov)
  • Amiodarone is a vasodilator which was found to be an effective anti-arrhythmic agent and is consequently in common usage. (radiopaedia.org)