• The vasodilative response to the endothelium-dependent vasodilator, methacholine chloride, was depressed in the hypercholesterolemic group, whereas endothelium-independent vasodilation, induced by nitroprusside, was similar in each group. (jci.org)
  • Sixteen healthy, nonsmoking women were studied, each on four occasions during one 24-h period (2:00 PM, 8:00 PM, 2:00 AM, and 8:00 AM). Endothelial function was assessed by ultrasound determinations of flow-mediated vasodilation (FMD%) in the brachial artery. (lu.se)
  • We have shown that nanoparticle inhalation impairs endothelium-dependent vasodilation in coronary arterioles. (cdc.gov)
  • L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans. (jci.org)
  • It is concluded that endothelium-dependent vasodilation is impaired in hypercholesterolemic humans. (jci.org)
  • Vascular complications are responsible for the excess mortality associated with diabetes ( 1 ), and impaired endothelium-dependent vasodilation has been described in humans and in animal models of the disease ( 2 - 6 ). (diabetesjournals.org)
  • abstract = 'Aims: The aim of this study is to examine whether colchicine improves β adrenoceptor-mediated vasodilation in humans by conducting a double-blinded, placebo-controlled intervention study. (ku.dk)
  • Studies in isolated rodent arteries have shown that colchicine can enhance β adrenoceptor-mediated vasodilation, but this has not been determined in humans.Methods: Middle-aged men with essential hypertension were randomly assigned firstly to acute treatment with either 0.5 mg colchicine (n=19) or placebo (n=12). (ku.dk)
  • The results provide novel translational evidence for a transient enhancing effect of colchicine on β adrenoceptor-mediated vasodilation in humans with essential hypertension. (ku.dk)
  • These results suggest the presence of functional α 7 -nAChRs on postganglionic sympathetic adrenergic nerve terminals of SCG origin, which mediate nicotine-induced neurogenic NOergic vasodilation. (aspetjournals.org)
  • Adenosine (ADO) is one of several endogenous substances known to mediate muscle vasodilation during exercise. (concordia.ca)
  • These studies demonstrate that beta(1)-adrenergic receptors play a dominant role in the murine vascular system to mediate vasodilation. (meltingpointathens.com)
  • At lower levels of circulating epinephrine, β-adrenoceptor stimulation dominates, producing an overall vasodilation. (meltingpointathens.com)
  • Vasodilation directly affects the relationship between mean arterial pressure, cardiac output, and total peripheral resistance (TPR). (wikipedia.org)
  • Significant vasodilation in the arterial splanchnic district is crucial for an increase in portal flow. (karger.com)
  • Conversely, even prolonged intra-arterial infusion of secretin does not release pancreatic stores of histamine: In fact, endogenous synthesis and release of histamine seem to play no role in the regulation of functional vasodilation in the pancreas. (erowid.org)
  • Atropine (250-550 mcg) inhibits vasodilation and decreases the secretory response of the pancreas to secreting Previous intra-arterial injection of bradykinin restores the secretory response of the pancreas, thus showing that inhibitory effect of, of the atropine on the secretory response of the pancreas to secretin is partly mediated by inhibition of secretin-induced vasodilation. (erowid.org)
  • Biossays of sera extracted from arterial and venous chest blond on guinea pig ileum seem to indicate that vasodilation in the pancreatic vascular bed These is acompanied by release of active bradykinin into the venous effluent. (erowid.org)
  • The vasodilator responses to isoprenaline, acetylcholine and sodium nitroprusside were determined as well as arterial pressure, arterial compliance and plasma inflammatory markers.Results: Acute colchicine treatment increased isoprenaline (by 38% for the highest dose) as well as sodium nitroprusside (by 29% main effect) -induced vasodilation but had no effect on the response to acetylcholine. (ku.dk)
  • These approaches to the mechanism of vasodilation are not mutually exclusive. (wikipedia.org)
  • Here, we investigated the mechanism of the vasodilation effect of wogonin on isolated rat thoracic aortas. (niscpr.res.in)
  • Nerve cells do so by releasing neuromediators such as substance P (SP), which acts on both the vascular bed to cause vasodilation and increase permeability, and on skin cells to promote the release of pro-inflammatory cytokines including some interleukins (IL-1 and IL-8) and tumor necrosis factor-alpha (TNF-α). (cosmeticsandtoiletries.com)
  • We aimed to determine: 1) the concentration of polyphenols in Spanish red wines, 2) the vasodilatory properties of those wines in relation with their polyphenol concentrations and 3) the vasodilation induced by some of these polyphenols in rat aortic rings. (lacienciadelvino.com)
  • Reactive vasodilation was not observed. (nau.edu)
  • Putting it in simple terms, vasodilation is a process that relaxes the blood vessel walls to allow veins and arteries to attain a slightly larger diameter. (labmeeting.com)
  • How Does Vasodilation Rid the Muscles of Unwanted Chemicals? (labmeeting.com)
  • Such feelings are very hard to "work through", but whenever the blood supply is increased by vasodilation the cardiovascular system is able to flush the muscles of unwanted chemicals more efficiently. (labmeeting.com)
  • How Does Vasodilation Feed the Muscles? (labmeeting.com)
  • Its most important function throughout the body is vasodilation, which is the relaxation and widening of the inner muscles of your blood vessel. (newstarget.com)
  • Endogenous substances and drugs that cause vasodilation are termed vasodilators. (wikipedia.org)
  • These findings suggest that upregulated expression of p22phox mRNA and enhanced NADH oxidase activity contribute to the impaired endothelium-dependent vasodilation in OLETF rats. (diabetesjournals.org)
  • Coincubation with 2,2,6,6-tetramethylpiperidine-N-oxyl and catalase ameliorated impairments in ACh-induced vasodilation from nanoparticle exposed rats. (cdc.gov)
  • Incubation with either L-NMMA or indomethacin significantly attenuated ACh-induced vasodilation in sham-control rats, but had no effect in rats exposed to nano-TiO2. (cdc.gov)
  • Vasodilation is the result of relaxation in smooth muscle surrounding the blood vessels. (wikipedia.org)
  • Dephosphorylation by myosin light-chain phosphatase and induction of calcium symporters and antiporters that pump calcium ions out of the intracellular compartment both contribute to smooth muscle cell relaxation and therefore vasodilation. (wikipedia.org)
  • Group I metabotropic glutamate receptors (mGluR) on astrocytes have been shown to participate in cerebral vasodilation to neuronal activation in brain slices. (elsevierpure.com)
  • We conclude that NO does playa role in mediating ADO-induced vasodilation and there is a lack of autoregulatory feedback when ADO is infused during exercise. (concordia.ca)
  • Heat syncope-sudden fainting caused by vasodilation-occurs in unacclimated people standing in the heat or after 15-20 minutes of exercise. (cdc.gov)
  • After pancreatic stores of photohistamine have been released by compound 48/80, secretin-induced vasodilation still work occurs. (erowid.org)
  • Medics outline vasodilation as a physique's pure response to a rise in physique temperature or diminished oxygen ranges. (cbdoilboard.com)
  • Vasodilation is a unconscious response, therefore it can't be prevented from occurring. (cbdoilboard.com)
  • Neuroleptic drugs also predispose a person to hypothermia by inducing vasodilation and suppressing the shivering response. (cdc.gov)
  • Conclusion: These findings suggest that endothelium mediated vasodilation is preserved in CHF, but that increased extravascular compressive forces act to limit the increase in CBF. (umn.edu)
  • Relationship between vasodilation capacity and phenolic content of Spanish wines. (lacienciadelvino.com)
  • The primary function of vasodilation is to increase blood flow in the body to tissues that need it most. (wikipedia.org)
  • Localized tissues have multiple ways to increase blood flow, including releasing vasodilators, primarily adenosine, into the local interstitial fluid, which diffuses to capillary beds, provoking local vasodilation. (wikipedia.org)
  • Since the common denominator in these diseases is lack of blood flow to the brain, NO's vasodilation, anti-inflammatory, and blood-thinning properties are a powerful weapon against dementia. (newstarget.com)
  • Vasodilation also happens naturally in the body on a day-to-day basis with a variety of triggers like temperature increases, low levels of oxygen or a nutrient decrease. (cryospaclinics.com.au)
  • Vasodilation helps more oxygen-rich blood to travel freely throughout your body and get to where it needs to go in order to keep you healthy, fit, and strong. (newstarget.com)
  • Bearing in mind all the benefits vasodilation can supply it is not surprising so many supplement manufacturers have developed formulations that aim to boost NO levels. (labmeeting.com)
  • It also prompts vasodilation , further increasing the oxygenation of important organs such as the lungs, brain, heart, and skeletal muscle. (jackwestin.com)
  • It's referred to as vasodilation and it has a number of results on our our bodies. (cbdoilboard.com)
  • This study demonstrates a diurnal variation in both endothelium-dependent and -independent vasodilation in the brachial artery of healthy women. (lu.se)
  • It contains a special blend of arginine and silicate that is proven to provide effective vasodilation without presenting any health risks. (labmeeting.com)