• occur
  • Generalized vasoconstriction usually results in an increase in systemic blood pressure, but it may also occur in specific tissues, causing a localized reduction in blood flow. (wikipedia.org)
  • vascular
  • The mechanism that leads to vasoconstriction results from the increased concentration of calcium (Ca 2+ ions ) within vascular smooth muscle cells . (wikipedia.org)
  • There are two distinct populations of α-adrenergic receptors (α 1 and α 2 ) found of vascular smooth muscle, both of which produce vasoconstriction when stimulated. (lww.com)
  • Causes
  • This depolarization activates voltage-dependent calcium channels, which increases intracellular calcium and activates smooth muscle contractile machinery which in turn causes vasoconstriction. (wikipedia.org)
  • receptors
  • 20 - 26 Furthermore, inhibitory effects of 17β-estradiol on COX-dependent responses to vasoconstrictors have suggested a role of estrogen receptors, 27 although the specific estrogen receptor(s) involved in endothelium-dependent vasoconstriction have not been identified. (ahajournals.org)
  • We have shown an attenuation of vasoconstriction during exercise with simultaneous stimulation of both populations of receptors. (lww.com)
  • decrease
  • Similar postangioplasty vasoconstriction was observed in the pig carotid arteries (decrease in minimal vessel cross-sectional area of 41% [angioplasty segment] versus 2% [control segment]) (p less than 0.005). (ahajournals.org)
  • mechanisms
  • These two compounds are transported to the smooth muscle and there react with cytochrome P450 to make 20-hydroxyeicosatetraenoic acid (20-HETE), which acts through yet to-be-determined mechanisms to induce vasoconstriction. (wikipedia.org)