• HSP nephritis and pulmonary findings may be confused with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. (
  • With great interest we read the clinical review by Berden and co-authors regarding ANCA associated vasculitis. (
  • As is known, ANCA associated vasculitis is characterized by necrotizing granulomatous lesions that affect different vessels and organs, most commonly the kidney and lungs. (
  • the involve anti-neutrophil cytoplasmic antibody (ANCA) as a common pathogenesis .They can be detected by indirect immunofluoroscence and 2 staining pattern are known namely : perinuclear ( P-ANCA) and cytoplasmic ( C-ANCA) .he target organs of PANCA is myeloperoxidase (MPO) and for CANCA is proteinase 3(PR3) .These vasculitis leads to multi-organ involvement. (


  • Vasculitis is an inflammatory disease of blood vessels characterized by the alteration or destruction of the vessel wall. (


  • Revisiting the classification of clinical phenotypes of anti-neutrophil cytoplasmic antibody-associated vasculitis: a cluster analysis. (