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  • Advisory Committee
  • Children at special risk (e.g., sickle cell disease and asplenia) require as full protection as can be achieved using the 7-valent conjugated vaccine, with the more extensive 23-valent vaccine given after the second year of life: In 2001, the Centers for Disease Control (CDC), upon advice from its Advisory Committee on Immunization Practices, recommended the vaccine be administered to every infant and young child in the US. (wikipedia.org)
  • immunity
  • As with all polysaccharide vaccines, Menomune does not produce mucosal immunity, so people can still become colonised with virulent strains of meningococcus, and no herd immunity can develop. (wikipedia.org)
  • Individuals who are immunodeficient due to HIV/AIDS, lymphoma, leukemia, bone marrow cancer, an impaired spleen, chemotherapy, or radiotherapy may have lost any immunity that they previously had and vaccines may not be of any use for them because of their immunodeficiency. (wikipedia.org)
  • Vaccines are typically imperfect as some individuals' immune systems may not generate an adequate immune response to vaccines to confer long-term immunity, so a portion of those who are vaccinated may lack immunity.Lastly, vaccine contraindications may prevent certain individuals from becoming immune. (wikipedia.org)
  • influenza vaccines
  • Influenza (flu) is more severe in the elderly than in younger age groups, but influenza vaccines lack effectiveness in this demographic due to a waning of the immune system with age. (wikipedia.org)
  • GlaxoSmithKline
  • Rino Rappuoli is Chief Scientist & Head of External Research and Development (R&D) at GlaxoSmithKline (GSK) Vaccines. (wikipedia.org)
  • Rappuoli, was previously the Global Head of Vaccines Research for Novartis Vaccines & Diagnostics (Siena, Italy) Since 2015, Dr. Rappuoli serves as the Chief Scientist and Head of External R&D at the vaccines division of GlaxoSmithKline and is based in Siena, Italy. (wikipedia.org)
  • bacterial vaccines
  • George Siber served as the Assistant Director and Head of Bacterial Vaccines for the Massachusetts Public Health Biological Laboratories in Jamaica Plain, Massachusetts between 1982 and 1983. (wikipedia.org)
  • infection
  • Due to the serious nature of infections caused by N meningiditis , vaccines have been developed to protect against the infection. (aappublications.org)
  • The purpose of this study is to test the safety and favorable immune response to an anti-streptococcal vaccine (a vaccine that treats a common bacterial infection) in healthy non-pregnant women. (clinicaltrials.gov)
  • immunization
  • The World Health Organization (WHO) and UNICEF have recognized the safety and effectiveness of PCVs and recommend that these vaccines for young children be included in national immunization programs ( 1 ). (cdc.gov)
  • Some of the 193 countries that are WHO member states have made national decisions to provide vaccine to all children through their national immunization programs. (cdc.gov)
  • The vaccine had been introduced into the national childhood immunization programs as a vaccine for all children or was in widespread use in 26 (13%) member states ( Figure ). (cdc.gov)
  • In the 2009 National Immunization Survey-Teen, 53.6% of adolescents aged 13 through 17 years had received a dose of meningococcal vaccine ( 3 ). (cdc.gov)
  • Some forms of meningitis are preventable by immunization with the meningococcal, mumps, pneumococcal, and Hib vaccines. (wikipedia.org)
  • Therefore, if a recently quit tobacco smoker is vaccinated and has a tobacco cigarette after the immunization series is completed, the antibodies generated by the vaccine bind nicotine and alter its distribution into the brain. (wikipedia.org)
  • Rappuoli
  • Rappuoli joined Chiron as head of European vaccines research in 1992 with the acquisition of Italian vaccines company Sclavo SpA, where he served as head of research and development. (wikipedia.org)
  • PCV7
  • The high cost of PCV7 has restricted the number of countries introducing the vaccine. (cdc.gov)
  • Other countries have elected to offer PCV7 vaccine only to certain high-risk groups, such as children who are HIV positive or other immunocompromised or chronically ill persons. (cdc.gov)
  • no booster) for infant pneumococcal conjugate vaccine since January 2005, initially 7-valent (PCV7) then 13-valent. (bioportfolio.com)
  • prevention
  • After waiting for the outcome of a trial underway in the Netherlands, the Centers for Disease Control and Prevention (CDC) recommended the vaccine for adults over age 65 in August 2014. (wikipedia.org)
  • Lee CJ, Lee LH, Koizumi K. (2002) Polysaccharide Vaccines for Prevention of Encapsulated Pseudomonas Aueroginosa Bacterial Infections: Part 1. (wikipedia.org)
  • Halsey's research is primarily directed toward the prevention of infectious diseases with the safest vaccines possible. (wikipedia.org)
  • work in vaccines
  • From 1993-1999, Lees was also part-time at Virion Systems, Inc. (Rockville, MD) . Lees was appointed Associate Research Professor (Department of Medicine) at USUHS in 1998 and the School cited his work in vaccines in his Meritorious Service Award (1999). (wikipedia.org)
  • He is known globally for his work in vaccines and immunology. (wikipedia.org)
  • safety of vaccines
  • VAERS, operated by CDC and the Food and Drug Administration (FDA), is a national passive surveillance system that monitors the safety of vaccines ( 2 ). (cdc.gov)
  • pneumococcus
  • Vaccinating children against pneumococcus and rotavirus has had the effect of reducing pneumococcus- and rotavirus-attributable hospitalizations for older children and adults, who do not normally receive these vaccines. (wikipedia.org)
  • Siber
  • George Rainer Siber (born September 7, 1944) is an internationally recognized medical researcher and vaccine expert with 42 years of experience in developing numerous vaccines, therapeutic antibodies, and diagnostic agents for infectious diseases. (wikipedia.org)
  • Siber joined ClearPath Vaccine Company in 2012 and became its Chief Scientific Officer in 2013. (wikipedia.org)
  • Siber was appointed to the Board of Trustees of the International Vaccine Institute in Korea in 2014 and chairs the Board's Science Committee. (wikipedia.org)
  • Siber also serves on the External Advisory Board of Aditec on behalf of the EC (2009 - present), the Korean FDA, (2011-present) and the Vaccine Advisory Committee of the Wistar Institute in Philadelphia (2012-present). (wikipedia.org)
  • infections
  • The antibiotic courses required to treat infections promote antibiotic resistance, and current vaccine options offer limited protection. (pnas.org)
  • immune
  • The siderophore-protein conjugates elicited an adaptive immune response that targeted bacterial stealth siderophores and protected against UTI. (pnas.org)
  • The conjugate formulations show responses which are consistent with T-cell recruitment (namely a much stronger immune response). (wikipedia.org)
  • Conjugate vaccines are used to produce an immune response in these cases. (wikipedia.org)
  • the 3'-aminomethylnicotine molecule found in the vaccine instigates an immune response in which 'nicotine' antibodies are created. (wikipedia.org)
  • Adults
  • Pneumovax 23, Merck & Co. Inc.), the vaccine currently recommended for these groups of adults ( 1 ). (cdc.gov)
  • 2017
  • The November 2017 edition of National Geographic Magazine published "Here's Why Vaccines Are So Crucial", an article revolving around the need and impact of vaccines in society and vividly highlighted the lifelong dedication of Saha's fight to beating pneumonia and other pneumococcal infections in Bangladesh. (wikipedia.org)
  • protein
  • Rindopepimut (CDX-110) is an injectable peptide cancer vaccine which targets a mutant protein called EGFRvIII present in about 25% to 30% of glioblastoma cases. (wikipedia.org)
  • Through reductive amination, the sugars are directly conjugated to the protein carrier CRM197 to form the glycoconjugate. (wikipedia.org)
  • Some regulatory agencies use the terms biological medicinal products or therapeutic biological product to refer specifically to engineered macromolecular products like protein- and nucleic acid-based drugs, distinguishing them from products like blood, blood components, or vaccines, which are usually extracted directly from a biological source. (wikipedia.org)
  • 2001
  • Children at special risk (e.g., sickle cell disease and asplenia) require as full protection as can be achieved using the 7-valent conjugated vaccine, with the more extensive 23-valent vaccine given after the second year of life: In 2001, the Centers for Disease Control (CDC), upon advice from its Advisory Committee on Immunization Practices, recommended the vaccine be administered to every infant and young child in the US. (wikipedia.org)
  • colleagues
  • Janda and colleagues then showed that an active vaccine against the orexigenic hormone ghrelin can slow the rate of weight gain, and adiposity, and do this through an entirely metabolic mechanism, as food intake was unchanged. (wikipedia.org)
  • disease
  • Our framework offers the possibility to advance immune-repertoire-based fingerprinting, which may in the future enable a systems immunogenomics approach for vaccine profiling and the accurate and early detection of disease and infection. (beds.ac.uk)
  • At Boston Children's Hospital in 1968 Anderson began vaccine research to prevent Hib disease along with David H. Smith and Richard Insel. (wikipedia.org)
  • and as an advisor to the Center for Disease Control's Anthrax Vaccine Program in 2002. (wikipedia.org)
  • He then derived a vaccine by altering the infectious agent so as to make it harmless and then introducing this inactivated form of the infectious agents into farm animals, which then proved to be immune to the disease. (wikipedia.org)
  • After waiting for the outcome of a trial underway in the Netherlands, the Centers for Disease Control and Prevention (CDC) recommended the vaccine for adults over age 65 in August 2014. (wikipedia.org)
  • It carries a high mortality rate if untreated but is a vaccine-preventable disease. (wikipedia.org)
  • given
  • This vaccine is given as a series of shots, the first dose is given at birth, the second between 1 and 2 months, and the third, and possibly fourth, between 6 and 18 months. (wikipedia.org)
  • This vaccine is a 2 or 3 dose series, depending on the brand of the vaccine, that is given at 2 and 4 months in the 2 dose series and at 2,4 and 6 months in the 3 dose series. (wikipedia.org)
  • If this were to happen, it would occur within a week after the first dose or second dose of the vaccine is given. (wikipedia.org)
  • Program
  • In May 2005, the National Immunisation Program (NIP) Schedule replaced the ASVS (Table 16), with all recommended vaccines to be funded. (health.gov.au)
  • Center
  • After the publication of the article Saha was invited to attend a panel discussion on the various aspects of pneumococcal vaccines and vaccines in general, hosted and broadcast by National Geographic, and the Bill and Melinda Gates Foundation at the International Vaccine Access Center, the Johns Hopkins Bloomberg School of Public Health, Baltimore, USA. (wikipedia.org)
  • human
  • Ovandrotone albumin (INN, BAN) (brand names Fecundin, Ovastim), also known as polyandroalbumin, as well as ovandrotone:human serum albumin conjugate, is an immunogen and vaccine against androstenedione that is used in veterinary medicine to increase the ovulation rate and number of lambs born to ewes. (wikipedia.org)
  • It is a conjugate of ovandrotone (androstenedione-7α-carboxyethylthioether) and human serum albumin. (wikipedia.org)
  • develop
  • The techniques he and his colleague Ronald Eby invented were later utilized to develop a vaccine against Streptococcus pneumoniae. (wikipedia.org)
  • people
  • For Aboriginal and Torres Strait Islander people who have at least one risk factor for which the vaccine is recommended, as per The Australian Immunisation Handbook, 9th edition. (health.gov.au)