• influenza vaccines
  • Influenza (flu) is more severe in the elderly than in younger age groups, but influenza vaccines lack effectiveness in this demographic due to a waning of the immune system with age. (wikipedia.org)
  • GlaxoSmithKline
  • Rino Rappuoli is Chief Scientist & Head of External Research and Development (R&D) at GlaxoSmithKline (GSK) Vaccines. (wikipedia.org)
  • Rappuoli, was previously the Global Head of Vaccines Research for Novartis Vaccines & Diagnostics (Siena, Italy) Since 2015, Dr. Rappuoli serves as the Chief Scientist and Head of External R&D at the vaccines division of GlaxoSmithKline and is based in Siena, Italy. (wikipedia.org)
  • pneumococcus
  • In the same manner, children receiving vaccines against pneumococcus reduces pneumococcal disease incidence among younger, unvaccinated siblings. (wikipedia.org)
  • Vaccinating children against pneumococcus and rotavirus has had the effect of reducing pneumococcus- and rotavirus-attributable hospitalizations for older children and adults, who do not normally receive these vaccines. (wikipedia.org)
  • A pilot Advance Market Commitment (AMC) to develop a vaccine against pneumococcus was launched in June 2009 as a strategy to address two of the major policy challenges to vaccine introduction: a lack of affordable vaccines on the market, and insufficient commercial incentives to develop vaccines for diseases concentrated in developing countries. (wikipedia.org)
  • dose
  • Tripedia vaccine (vial presentation 0.6 mL) is formulated without preservatives but contains a trace amount of thimerosal [(mercury derivative), ( ≤ 0.3 mcg mercury/dose)] from the manufacturing process. (rxlist.com)
  • Mozambique introduced 10-valent pneumococcal conjugate vaccine (PCV10) in April 2013, using a 3-dose schedule without a booster. (bioportfolio.com)
  • Effectiveness of Seven and Thirteen Valent Pneumococcal Conjugate Vaccines in a Schedule without a Booster dose: a Ten Year Observational Study. (bioportfolio.com)
  • The wholesale cost of a pentavalent vaccine which includes Hib in the developing world was 15.40 USD per dose as of 2014. (wikipedia.org)
  • generally the vaccine should be a single lifetime dose, as there is a high risk of side effects if repeated. (wikipedia.org)
  • immune
  • The purpose of this initial small study is to monitor safety of the vaccine and to determine whether it is appropriate to continue into future, larger studies in which the immune response to the vaccine is measured. (clinicaltrials.gov)
  • The conjugate formulations show responses which are consistent with T-cell recruitment (namely a much stronger immune response). (wikipedia.org)
  • Conjugate vaccines are used to produce an immune response in these cases. (wikipedia.org)
  • Vaccines are typically imperfect as some individuals' immune systems may not generate an adequate immune response to vaccines to confer long-term immunity, so a portion of those who are vaccinated may lack immunity.Lastly, vaccine contraindications may prevent certain individuals from becoming immune. (wikipedia.org)
  • the 3'-aminomethylnicotine molecule found in the vaccine instigates an immune response in which 'nicotine' antibodies are created. (wikipedia.org)
  • The polysaccharide vaccines, while effective in healthy adults, are not effective in children less than two years old or those with poor immune function. (wikipedia.org)
  • work in vaccines
  • From 1993-1999, Lees was also part-time at Virion Systems, Inc. (Rockville, MD) . Lees was appointed Associate Research Professor (Department of Medicine) at USUHS in 1998 and the School cited his work in vaccines in his Meritorious Service Award (1999). (wikipedia.org)
  • He is known globally for his work in vaccines and immunology. (wikipedia.org)
  • safety of vaccines
  • VAERS, operated by CDC and the Food and Drug Administration (FDA), is a national passive surveillance system that monitors the safety of vaccines ( 2 ). (cdc.gov)
  • Siber
  • George Rainer Siber (born September 7, 1944) is an internationally recognized medical researcher and vaccine expert with 42 years of experience in developing numerous vaccines, therapeutic antibodies, and diagnostic agents for infectious diseases. (wikipedia.org)
  • Siber joined ClearPath Vaccine Company in 2012 and became its Chief Scientific Officer in 2013. (wikipedia.org)
  • Siber was appointed to the Board of Trustees of the International Vaccine Institute in Korea in 2014 and chairs the Board's Science Committee. (wikipedia.org)
  • Siber also serves on the External Advisory Board of Aditec on behalf of the EC (2009 - present), the Korean FDA, (2011-present) and the Vaccine Advisory Committee of the Wistar Institute in Philadelphia (2012-present). (wikipedia.org)
  • George Siber served as the Assistant Director and Head of Bacterial Vaccines for the Massachusetts Public Health Biological Laboratories in Jamaica Plain, Massachusetts between 1982 and 1983. (wikipedia.org)
  • prevention
  • After waiting for the outcome of a trial underway in the Netherlands, the Centers for Disease Control and Prevention (CDC) recommended the vaccine for adults over age 65 in August 2014. (wikipedia.org)
  • Halsey's research is primarily directed toward the prevention of infectious diseases with the safest vaccines possible. (wikipedia.org)
  • Rappuoli
  • Rappuoli joined Chiron as head of European vaccines research in 1992 with the acquisition of Italian vaccines company Sclavo SpA, where he served as head of research and development. (wikipedia.org)
  • Pneumovax
  • Pneumovax 23, Merck & Co. Inc.), the vaccine currently recommended for these groups of adults ( 1 ). (cdc.gov)
  • immunity
  • Newborn infants are too young to receive many vaccines, either for safety reasons or because passive immunity renders the vaccine ineffective. (wikipedia.org)
  • Individuals who are immunodeficient due to HIV/AIDS, lymphoma, leukemia, bone marrow cancer, an impaired spleen, chemotherapy, or radiotherapy may have lost any immunity that they previously had and vaccines may not be of any use for them because of their immunodeficiency. (wikipedia.org)
  • Novartis
  • Previously, he has served as visiting scientist at Rockefeller University and Harvard Medical School and held roles at Sclavo, Vaccine Research and CSO, Chiron Corporation, and Novartis Vaccines. (wikipedia.org)
  • meningococcus
  • Different versions are effective against some or all of the following types of meningococcus: A, C, W-135, and Y. The vaccines are between 85 and 100% effective for at least two years. (wikipedia.org)
  • In Canada and the United States the vaccines effective against all four types of meningococcus are recommended routinely for teenagers and others who are at high risk. (wikipedia.org)
  • the meningococcus B genome-derived vaccine. (wikipedia.org)