• compound
  • Trabectedin is yet another example of a compound from the marine source, the Caribbean marine tunicate Ecteinascidia turbinata , which has passed all steps of development into a pharmaceutical agent and is approved for patients with advanced or metastatic soft-tissue sarcoma or ovarian carcinoma ( 10 ). (aacrjournals.org)
  • It is unique amongst uncouplers in displaying broad-spectrum activity against fungi and also very low toxicity to mammals due to it being rapidly metabolised to a compound without uncoupling activity. (wikipedia.org)
  • known
  • Mannomustine (INN), also known as mannitol nitrogen mustard, tradename Degranol is an old alkylating antineoplastic agent from the group of nitrogen mustards. (wikipedia.org)
  • cells
  • Consistent with this, telomerase-immortalised cells continued to age (according to the epigenetic clock) without having been treated with any senescence inducers or DNA-damaging agents, re-affirming the independence of the process of epigenetic ageing from telomeres, cellular senescence, and the DNA damage response pathway. (wikipedia.org)
  • Heterologous desensitization may occur in cells that are grossly overstimulated for prolonged times by a certain agents. (wikipedia.org)
  • taken
  • After a shootout, George and Grover jump off the train and are arrested and taken to a train station, where federal agent Donaldson explains that he planted the Stevens murder story to protect George. (wikipedia.org)
  • acts
  • Aspirin acts as an acetylating agent where an acetyl group is covalently attached to a serine residue in the active site of the COX enzyme. (wikipedia.org)