AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaInformation ScienceNamed GroupsHealth CareGeographicals
TuberculosisTuberculosis, PulmonaryMycobacterium tuberculosisTuberculosis, Multidrug-ResistantTuberculosis VaccinesTuberculosis, MiliaryIsoniazidLatent TuberculosisTuberculosis, Lymph NodeTuberculosis, OsteoarticularTuberculosis, GastrointestinalTuberculosis, SpinalTuberculosis, BovineTuberculosis, CutaneousTuberculin TestRifampinSputumMycobacterium bovisTuberculosis, PleuralExtensively Drug-Resistant TuberculosisTuberculosis, UrogenitalPyrazinamideAntibiotics, AntitubercularBCG VaccineTuberculosis, MeningealBacterial ProteinsTuberculosis, OcularTuberculosis, SplenicMycobacteriumTuberculosis, HepaticAntigens, BacterialTuberculosis, Female GenitalEthambutolMycobacterium smegmatisDirectly Observed TherapyTuberculosis, EndocrineTuberculosis, Central Nervous SystemTuberculosis, LaryngealTuberculosis, RenalDNA, BacterialTuberculosis, OralSensitivity and SpecificityMicrobial Sensitivity TestsDrug Resistance, BacterialBacteriological TechniquesContact TracingAIDS-Related Opportunistic InfectionsInterferon-gammaDNA FingerprintingTuberculinSouth AfricaPolymorphism, Restriction Fragment LengthLungMycobacterium InfectionsDrug Resistance, Multiple, BacterialTuberculosis, Male GenitalMycolic AcidsHIV InfectionsPolymerase Chain ReactionPeritonitis, TuberculousBacterial Typing TechniquesStreptomycinMycobacteriophagesGranulomaMacrophagesEthionamideEmigration and ImmigrationMolecular Sequence DataInterferon-gamma Release TestsDNA Transposable ElementsNontuberculous MycobacteriaCoinfectionCommunicable Disease ControlCapreomycinIndiaMolecular EpidemiologyCord FactorsRadiography, ThoracicReagent Kits, DiagnosticGenotypeMinisatellite RepeatsBacterial LoadGenes, BacterialGene Expression Regulation, BacterialDisease NotificationColony Count, MicrobialAminosalicylic AcidTuberculomaEthiopiaTime FactorsTuberculosis, CardiovascularIncidenceVirulencePrevalenceMolecular Diagnostic TechniquesMycobacterium marinumRetrospective StudiesCluster AnalysisPeruDiarylquinolines
MycobacteriumPulmonarySpleenMultiple splenicAbscessesInfectionDiagnosisAntigenComputed TomographyAsymptomaticEpidemiologyManifestationsWhom tuberculosisPancreaticUltrasonographyLymphAbscessLesionsSymptomsAcuteExtrapulmonaryIndiaTissueDiseasesInfectionsCutaneousCardiacSpecimensUltrasonographicSplenectomyRecombinantUnstableDiseaseInjuriesAbstract
Mycobacterium7
  • Tuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. (genome.jp)
  • BACKGROUND Although some studies have reported the presence of Mycobacterium tuberculosis (MTb) DNA in tissues affected by sarcoidosis, the data are conflicting. (bmj.com)
  • Mycobacterium tuberculosis (MTb) has long been a likely contender as the inciting antigen in sarcoidosis, although Koch's postulates have never been fulfilled. (bmj.com)
  • TB infection occurs when a person inhales droplet nuclei containing Mycobacterium tuberculosis organisms. (hiv.gov)
  • Cardiac tuberculosis refers to the rare infection of the heart with Mycobacterium tuberculosis . (radiopaedia.org)
  • BACKGROUND: Immunization of BALB/c mice with a recombinant adenovirus expressing Mycobacterium tuberculosis (M. tuberculosis) antigen 85A (Ad85A) protects against aerosol challenge with M. tuberculosis only when it is administered intra-nasally (i.n. (ox.ac.uk)
  • Using multiple murine foster-nursing protocols, thereby eliminating placental transfer and allowing a distinction between dam- and pup-derived cells, we show that foster nursing by an immunized dam results in development of CD8 + T cells in nonimmunized foster pups that are specific for Ags against which the foster dam was immunized ( Mycobacterium tuberculosis or Candida albicans ). (aai.org)
Pulmonary10
  • The most frequently affected sites of mucormycosis are pulmonary, rhino-orbital-cerebral, and cutaneous, while invasive splenic mucormycosis is extremely rare, with only a handful of cases documented in the literature. (frontiersin.org)
  • Initial chest X-ray (CXR) and pulmonary tuberculosis workups were all unremarkable. (rcpjournals.org)
  • Transient loss of resistance to pulmonary tuberculosis in p47 (phox --) mice. (forex-consultant.com)
  • Focused Assessment with Sonography for HIV-associated TB (FASH) is a diagnostic tool for extra-pulmonary tuberculosis (TB) in symptomatic patients with advanced HIV. (springeropen.com)
  • In settings endemic for HIV and tuberculosis (TB), the Focused Assessment with Sonography for HIV/TB (FASH) has been developed to assess patients for signs of extra-pulmonary TB [ 2 ]. (springeropen.com)
  • FASH is aimed at patients with HIV who present with symptoms, such as cough, weight loss, fever and night sweats, which are all consistent with extra-pulmonary tuberculosis. (springeropen.com)
  • Generally associated with and occurring as a complication of mediastinal and pulmonary tuberculosis . (radiopaedia.org)
  • In order to determine why the i.n. route is so effective compared to parenteral immunization, we used microarray analysis to compare gene expression profiles of pulmonary and splenic CD8 T cells after i.n. or intra-dermal (i.d.) immunization. (ox.ac.uk)
  • However, the unsatisfactory performance of BCG in controlling the adult pulmonary tuberculosis has made the development of an effective vaccine against M. tuberculosis a prime objective of the TB research. (nature.com)
  • acr was able to efficiently boost the BCG induced protection against M. tuberculosis infection in guinea pigs by significantly reducing the pulmonary bacillary load (1.27 log 10 fewer bacilli) in comparison to BCG vaccination alone. (nature.com)
Spleen11
  • Immunohistochemical staining demonstrated Rickettsia in endothelial cells and macrophages in the spleen and skin ( Figure , panels D - F ). Blood culture, skin biopsy specimens, and splenic tissue cultures were subsequently R. conorii positive. (cdc.gov)
  • The spleen, sometimes called "the forgotten organ" of the abdomen, has received less attention than other abdominal solid organs, as splenic diseases are less common and frequently clinically asymptomatic [ 1 ]. (e-ultrasonography.org)
  • Accessory spleen, which results from a failure of the embryonic splenic anlage to fuse and extreme lobulation that separates splenic tissue, is a normal variant observed in 10%-30% of individuals [ 7 ]. (e-ultrasonography.org)
  • The most common finding in the spleen was splenic rupture and haemoperitoneum from road traffic accident. (bvsalud.org)
  • Splenic infarction is a result of ischemia to the spleen , and in many cases requires no treatment. (radiopaedia.org)
  • Splenic infarcts can occur due to a number of processes, involving either arterial supply, the spleen itself or the venous drainage. (radiopaedia.org)
  • Spleen peliosis may be idiopathic or associated with infections such as tuberculosis and Bartonella, hematological diseases such as myeloma, myelofibrosis, and Hodgkin's disease and with the use of androgenic steroids and erythropoetin. (healthjade.com)
  • An enlarged spleen can be the cause of hypersplenism, that is, sequestration and excessive destruction of blood cells (usually all, although it is limited to 1 or 2 cell lines) by splenic macrophages. (acnm-online-pharmacy-usa-store.com)
  • Acute splenic sequestration crisis can be serious and a potentially life-threatening problem if the spleen suddenly enlarges with a large drop in the blood count. (texas.gov)
  • If a child experiences several episodes of splenic sequestration, surgery to remove the spleen may be considered. (texas.gov)
  • The splenic artery brings blood to the spleen from. (msdmanuals.com)
Multiple splenic1
  • A CT scan revealed splenomegaly with multiple splenic cysts and free intraperitoneal fluid consistent with blood. (healthjade.com)
Abscesses2
  • His CT scan revealed splenic abscesses, hepatomegaly and bilateral lung consolidation. (rcpjournals.org)
  • The protocol includes an assessment of pericardial and pleural effusions, ascites, abdominal lymphadenopathy and splenic micro abscesses. (springeropen.com)
Infection10
  • Tuberculosis-associated hemophagocytic lymphohistiocytosis (TB-HLH) is a rare and life-threatening complication of tuberculosis infection. (rcpjournals.org)
  • Getahun H, Gunneberg C, Granich R, Nunn P. HIV Infection-Associated Tuberculosis: The Epidemiology and the Response . (myhivclinic.org)
  • TB disease (defined as clinically active disease, often with positive smears and cultures) can develop soon after exposure to M. tuberculosis organisms (primary disease) or after reactivation of latent infection. (hiv.gov)
  • The two current diagnostics available for detection of M. tuberculosis infection in the United States, IGRA and TST, help differentiate those with and without TB infection. (hiv.gov)
  • Treatment: Chemotherapy and radiotherapy present poor Infection: Typical and atypical tuberculosis, histoplascontrol. (cpanet.com)
  • Cutaneous miliary tuberculosis in two patients with HIV infection. (ucdenver.edu)
  • HspX or α-crystallin, a 16 kDa protein, is one of the dominant antigens expressed during the latent stages of M. tuberculosis infection and under various other conditions like low oxygen tension, nutrient starvation or hypoxia 7 , 8 . (nature.com)
  • In one of the study from our laboratory, we have shown that a DNA vaccine expressing α-crystallin provides considerable protection to guinea pigs against M. tuberculosis infection 12 . (nature.com)
  • Early diagnosis and treatment are important in prevention of tuberculosis (TB) infection. (academicjournals.org)
  • Among the other 10 deaths associated with a nonpneumonia infectious process, 4 did not have an etiology assigned, the others were associated with miliary tuberculosis (2), cerebral thrombosis due to HIV (1), Enterobacteriaceae (1), rotavirus (1), and 1 case of respiratory infection with severe hypokalemia associated with RSV. (cdc.gov)
Diagnosis13
  • Missed splenic rupture or delayed diagnosis is associated with a 10-fold increase in mortality over the rate associated with prompt recognition of injury. (medscape.com)
  • The diagnosis of tuberculosis can be challenging, especially in low-incidence regions or in the case of an atypical clinical picture, such as ours, in which laryngeal carcinoma was suspected, but due to the lack of etiological diagnosis and targeted treatment, the outcome was the unexpected death of the patient. (archbronconeumol.org)
  • This case aims to emphasize the importance of utilizing mNGS and CEUS for the timely diagnosis of mucormycosis to help clinicians identify splenic mucormycosis and initiate appropriate therapy as soon as possible to improve therapeutic efficacy and prognosis. (frontiersin.org)
  • However, the clinical manifestations of splenic mucormycosis are non-specific, leading to frequent delays in diagnosis. (frontiersin.org)
  • The aim of this case is to emphasize the importance of utilizing mNGS and CEUS in the diagnosis of mucormycosis to help clinicians identify splenic mucormycosis and initiate appropriate therapy as soon as possible to improve therapeutic efficacy and prognosis. (frontiersin.org)
  • 4 Where the organism is found in sarcoid-like granulomas, the diagnosis is usually considered to be tuberculosis. (bmj.com)
  • Its noninvasiveness, extensive range of application, and low cost make US a useful and valuable tool for the detection, diagnosis, and follow-up of splenic abnormalities. (e-ultrasonography.org)
  • Concomitantly with the increasing frequency of imaging, more splenic lesions are being discovered and the requirements for the differential diagnosis are rising. (e-ultrasonography.org)
  • Knowledge of the US features of various splenic lesions will help narrow the differential diagnosis and guide clinical decision-making. (e-ultrasonography.org)
  • Ultrasonography is a useful and valuable tool for the detection, diagnosis, and follow-up of splenic abnormalities. (e-ultrasonography.org)
  • However, with the increasing frequency of imaging and advances in imaging technology, more incidental splenic lesions are being discovered and the subsequent requirements for the differential diagnosis are growing. (e-ultrasonography.org)
  • Bhansali reported no cases cal findings, a diagnosis of pancreatic TB of pancreatic TB in a series of 300 cases of was made and the patient was put on an- abdominal tuberculosis in India [ 9 ]. (who.int)
  • A differential diagnosis will often include malignant, infiltrative, or infectious conditions, as well as post-traumatic splenic cysts. (healthjade.com)
Antigen1
  • Immunization with Ad85A induces a lung-resident population of activated CD8 T cells that is antigen dependent, highly activated and mediates protection by early inhibition of M. tuberculosis growth. (ox.ac.uk)
Computed Tomography3
  • The American Association for the Surgery of Trauma (AAST) splenic injury scale is based on computed tomography (CT) findings, as follows. (medscape.com)
  • Coronal view of unenhanced abdominal computed tomography demonstrating splenic enlargement with endocapsular hematoma and intraperitoneal hemorrhage (arrows). (cdc.gov)
  • Therefore, this pictorial essay elucidates the US findings of various splenic lesions, in correlation with computed tomography (CT) or magnetic resonance (MR) imaging and pathology. (e-ultrasonography.org)
Asymptomatic2
  • It should be noted that ~40% (range 30-50%) of patients with splenic infarction are asymptomatic 9 . (radiopaedia.org)
  • Patients with isolated splenic peliosis may be asymptomatic or describe abdominal discomfort. (healthjade.com)
Epidemiology1
  • There is limited current information from developed international locations ered to be evidence of splenic enlargement,three however up to sixteen% of palon its epidemiology. (cpanet.com)
Manifestations1
  • Rare manifestations include lymph node disease resembling tuberculosis, mediastinal masses, pericardial effusion, mycotic aneurysm, and inflammation of the pancreas. (wikipedia.org)
Whom tuberculosis1
  • The aim of this study was to collect prospectively tissue from patients with sarcoidosis in whom tuberculosis had been excluded, and to use polymerase chain reaction (PCR) to search for DNA sequences specific for MTb. (bmj.com)
Pancreatic2
  • It is usually found around the splenic hilum or ligaments, pancreatic tail, or sometimes in the pancreatic parenchyma [ 7 ]. (e-ultrasonography.org)
  • Extrapulmonary TB is a diagnostic prob- trointestinal bleeding, pancreatic abscess, lem, especially when an unusual organ such chronic pancreatitis, diabetes and splenic as the pancreas is involved [ 6 ]. (who.int)
Ultrasonography1
  • Splenic mucormycosis was diagnosed by Contrast-Enhanced Ultrasonography (CEUS) and metagenomic next-generation sequencing (mNGS). (frontiersin.org)
Lymph1
  • Non Hodgkin's lymphoma (NHL) and tuberculosis were the most common lesions in lymph nodes and extranodal lymphoid tissues. (bvsalud.org)
Abscess1
  • We report a case of splenic abscess due to chronic melioidosis who was earlier misdiagnosed as tuberculosis and underwent anti-tuberculosis therapy. (openarchives.gr)
Lesions2
  • In this pictorial essay, we introduce the representative US findings of many different splenic lesions, including normal sonographic findings, normal variants and congenital anomalies, infectious conditions, benign and malignant neoplasms, and non-neoplastic lesions. (e-ultrasonography.org)
  • multiple infarcts appear as hypodense non-enhancing lesions, with normal intervening enhancing splenic tissue. (radiopaedia.org)
Symptoms3
  • The classic presentation of splenic injury includes hemodynamic instability, severe abdominal pain, and symptoms of peritonitis. (medscape.com)
  • The signs and symptoms of melioidosis resemble tuberculosis and misdiagnosis is common. (wikipedia.org)
  • What are the Symptoms of Splenic Sequestration? (texas.gov)
Acute1
  • We report a survival case of invasive splenic mucormycosis involving the liver caused by Rhizopus microsporus in a patient during consolidation therapy for acute monocytic leukemia (AML-M 5 ). (frontiersin.org)
Extrapulmonary2
India1
Tissue3
  • METHODS Fresh tissue samples (node or lung biopsy) taken from 23 patients with newly diagnosed sarcoidosis, 10 with other respiratory disease, and four patients with culture positive tuberculosis were analysed using PCR to amplify a 123 bp fragment of IS6110, the insertion element present in MTb, and nested PCR to further amplify an 85 bp sequence within the 123 bp product. (bmj.com)
  • RESULTS MTb DNA was not detected in any of the tissue samples from patients with sarcoidosis or other respiratory disease but was found in all four patients with tuberculosis. (bmj.com)
  • Morphologically the typical infarct is of a pyramidal wedge of affected splenic tissue with the apex pointing towards the hilum, and the base on the splenic capsule. (radiopaedia.org)
Diseases3
  • Un 40% de esos trabajos han sido publicados en revistas del primer cuartil entre las que destacan New England Journal of Medicine, Lancet, Lancet Infectious Diseases, Clinical Infectious Diseases, Clinical Microbiology Reviews, Antimicrobial Agents and Chemotherapy, Journal Clinical Microbiology, Journal Antimicrobial Chemotherapy, Mayo Clinic Proceedings y Malaria Journal. (unav.edu)
  • Therefore, US is widely used and frequently chosen as the first imaging modality for most abdominal imaging, both for general abdominal examinations and for patients suspected of having splenic diseases. (e-ultrasonography.org)
  • However, to the authors' knowledge, there are not enough up-to-date ultrasonographic imaging reviews of splenic diseases [ 2 - 5 ]. (e-ultrasonography.org)
Infections1
  • Infants and young children with sickle cell anemia who are between the ages of 2 months and 4 years are at greatest risk of splenic sequestration and infections. (texas.gov)
Cutaneous3
  • Tuberculosis, Cutaneous" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ucdenver.edu)
  • This graph shows the total number of publications written about "Tuberculosis, Cutaneous" by people in this website by year, and whether "Tuberculosis, Cutaneous" was a major or minor topic of these publications. (ucdenver.edu)
  • Below are the most recent publications written about "Tuberculosis, Cutaneous" by people in Profiles. (ucdenver.edu)
Cardiac1
Specimens1
  • Patients were enrolled in the study if they fulfilled previously accepted clinical diagnostic criteria, 15 had evidence of non-caseating granulomas on biopsy specimens, a negative Mantoux test, and negative MTb cultures with no prior history of tuberculosis. (bmj.com)
Ultrasonographic1
  • Ultrasonographic imaging showed inhomogeneous splenic parenchyma and increased size. (healthjade.com)
Splenectomy1
  • A computed tomographic scan showed hemoperitoneum secondary to a ruptured subcapsular splenic hematoma ( Appendix Figure ), and an emergency splenectomy was performed. (cdc.gov)
Recombinant1
  • In this study, a genetically stable, marker-free recombinant MVA expressing α-crystallin of M. tuberculosis (rMVA. (nature.com)
Unstable2
  • A FAST exam should be instituted in hemodynamically unstable patients with splenic trauma to assess the degree of both trauma and bleeding. (medscape.com)
  • Patients with grade IV or V splenic injuries are often unstable. (forex-consultant.com)
Disease3
  • Ten patients with other respiratory disease undergoing lung biopsy or mediastinoscopy acted as negative controls, and four patients with tuberculosis and culture positive nodes acted as positive controls. (bmj.com)
  • Tuberculosis (TB) is a common disease in 3 kg over the previous 2 months. (who.int)
  • One third of the world's population is infected latently with M. tuberculosis and is potentially at the risk of developing an active disease 1 , 2 . (nature.com)
Injuries2
  • A third mechanism for splenic trauma is explosive-type injuries, such as occurs in warfare and civilian bombing. (medscape.com)
  • If IV contrast is not used with CT, very significant splenic injuries may be missed by the lack of image optimization even with modern multi-detector CT scanning. (medscape.com)
Abstract1
  • A fevered lives tuberculosis in american for the address of a 1st cancer been on this example includes provided, and abstract photos of items for existing such a balance are encrypted. (towerprinting.com)