• malaria
  • In sub-Saharan Africa, the effect of these diseases as a group is comparable to malaria and tuberculosis. (wikipedia.org)
  • Produced in Morocco, this product is cheap (available at only $.05 for children, $1 for adults), administered in a simple regimen (1 or 2 tablets per day for 3 days), meets the latest WHO guidelines for malaria treatment in Africa and was granted "pre-qualified" status in 2008. (wikipedia.org)
  • DISEASES
  • Human African trypanosomiasis is on the World Health Organization's (WHO) list of neglected tropical diseases and since 2013 has become a target for eradication. (thefreedictionary.com)
  • Neglected tropical diseases (NTDs) are a diverse group of tropical infections which are especially common in low-income populations in developing regions of Africa, Asia, and the Americas. (wikipedia.org)
  • The Tse Tse habitat can be destroyed by alteration of vegetation so they can no longer live there.There are some drugs available that can prevent trypanosomiasis called prophylactic drugs.These drugs are very effective to protect animals during the times they are exposed to challenged diseases. (wikipedia.org)
  • reservoir
  • Most common in southern and eastern Africa, where game animals and livestock are thought to be the primary reservoir. (wikipedia.org)
  • known
  • Other animals, such as cows, may carry the disease and become infected in which case it is known as animal trypanosomiasis. (wikipedia.org)
  • Tsetse (/ˈsiːtsi/ SEET-see, US: /ˈtsiːtsi/ TSEET-see or UK: /ˈtsɛtsi/ TSET-see), sometimes spelled tzetze and also known as tik-tik flies, are large biting flies that inhabit much of tropical Africa. (wikipedia.org)
  • Pentamidine
  • African trypanosomes have a nucleoside (adenine/adenosine: P2) transporter that takes up pentamidine, resulting in the concentration of the agent at levels many times that in plasma [ 12 , 13 ]. (hindawi.com)
  • Winterbottom's
  • The term Winterbottom's sign derives from descriptions of the posterior cervical lymphadenopathy associated with African trypanosomiasis made by a slave trader using the sign to weed out the ill. (wikipedia.org)
  • Dr. Thomas Masterman Winterbottom (26 March 1766 in South Shields - 8 July 1859) was an English physician, philanthropist and abolitionist remembered for describing African trypanosomiasis and the associated Winterbottom's sign. (wikipedia.org)
  • disease
  • The disease occurs regularly in some regions of sub-Saharan Africa with the population at risk being about 70 million in 36 countries. (wikipedia.org)
  • 1) Control of the disease has been facilitated by the use of the card agglutination test for trypanosomiasis, which is particularly suited for large-scale screening of the populations at risk. (corisbio.com)
  • The tests were evaluated with the use of plasma from 198 patients with trypanosomiasis that was confirmed on parasitologic analysis and from 99 local controls with neither clinical nor serologic evidence of the disease. (corisbio.com)
  • There has been a resurgence of this disease over the past 20 years in Sub-Saharan Africa. (bio-medicine.org)
  • mainly
  • Africa is thus mainly composed of two segments at right angles, the northern running from east to west, and the southern from north to south. (wikipedia.org)
  • In addition, mixed race (European and African) people amount to about 2%, with a small (1%) population of whites, mainly ethnically Portuguese. (wikipedia.org)
  • countries
  • Three major outbreaks have occurred in recent history: one from 1896 to 1906 primarily in Uganda and the Congo Basin and two in 1920 and 1970 in several African countries. (wikipedia.org)
  • Failure rates of 27% in certain African countries have been reported. (wikipedia.org)
  • ASAQ is registered in 32 African countries, in India, Ecuador and in Colombia, and included in the . (wikipedia.org)
  • patients
  • 5) To evaluate the applicability of these tests when blood was used, samples of reconstituted blood were prepared by adding plasma from patients with trypanosomiasis or from local controls to sedimented blood cells from a healthy donor. (corisbio.com)
  • These cytokines and other metabolites such as nitric oxide and somnogenic prostaglandin D2 disturb circadian rhythms in patients with African trypanosomiasis. (genome.jp)
  • people
  • Roughly 37% of Angolans are Ovimbundu, 25% are Ambundu, 13% are Bakongo, 2% are mestiço, 1-2% are white Africans, and people from other African ethnicities make up 22% of Angola's population. (wikipedia.org)