High Triatoma brasiliensis Densities and Trypanosoma cruzi Prevalence in Domestic and Peridomestic Habitats in the State of Rio Grande do Norte, Brazil: The Source for Chagas Disease Outbreaks? (ajtmh.org)
Trypanosoma cruzi" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
This graph shows the total number of publications written about "Trypanosoma cruzi" by people in Harvard Catalyst Profiles by year, and whether "Trypanosoma cruzi" was a major or minor topic of these publication. (harvard.edu)
Below are the most recent publications written about "Trypanosoma cruzi" by people in Profiles. (harvard.edu)
Fatty acid elongases 1-3 have distinct roles in mitochondrial function, growth, and lipid homeostasis in Trypanosoma cruzi. (harvard.edu)
Cardiomyocyte infection by Trypanosoma cruzi promotes innate immune response and glycolysis activation. (harvard.edu)
mTOR signaling inhibition decreases lysosome migration and impairs the success of Trypanosoma cruzi infection and replication in cardiomyocytes. (harvard.edu)
Human Trypanosoma cruzi chronic infection leads to individual level steady-state parasitemia: Implications for drug-trial optimization in Chagas disease. (harvard.edu)
Trypanosoma cruzi IV causing outbreaks of acute Chagas disease and infections by different haplotypes in the Western Brazilian Amazonia. (unl.pt)
In this region, the sylvatic cycle of Trypanosoma cruzi transmission, which constitutes a reservoir of parasites that might be associated with specific molecular, epidemiological and clinical traits, has been little explored. (unl.pt)
In the Brazilian Amazon, clinical and epidemiological frameworks of Chagas disease are very dissimilar in relation to the endemic classical areas of transmission, possibly due to genetic and biological characteristics of the circulating Trypanosoma cruzi stocks. (unl.pt)
The protozoan parasite Trypanosoma cruzi (Kinetoplastida: Trypanosomatidae) is the causative agent of Chagas disease. (biomedcentral.com)
For instance Chagas disease, which is a neglected tropical disease caused by another parasite, Trypanosoma cruzi, can be highly benefited by T cell inducing vaccine. (ox.ac.uk)
In Trypanosoma , the two major human parasites are T. cruzi , the causative agent of Chagas' disease, and T. brucei , the causative agent of African sleeping sickness. (biomedcentral.com)
T. cruzi belongs to a major grouping within the genus Trypanosoma known as the American trypanosomes (or Stercoraria), while T. brucei belongs to another major grouping known as the African trypanosomes (or Salivaria). (biomedcentral.com)
Plasmodium9
In 1903, together with Alphonse Laveran (1845-1922), he showed that the parasite responsible for the visceral leishmaniasis (or "Kala-azar", a fever in India), first described by William Boog Leishman (1865-1926), is a new protozoa, different from Trypanosoma , the agent of the sleeping sickness, and from Plasmodium , the agent of paludism (malaria). (astro.com)
In 1920, he and Émile Roubaud achieved the first experimental infection of chimpanzees with Plasmodium vivax . (astro.com)
Chloroquine (CQ) and primaquine (PQ) are still the drugs of choice to treat Plasmodium vivax malaria in many endemic areas, Brazil included. (unl.pt)
In Latin America, data on chloroquine (CQ)-resistant Plasmodium vivax is limited, even with the current research efforts to sustain an efficient malaria control program in all these endemic countries, where malaria still is a major public health issue. (unl.pt)
These are known as Plasmodium vivax, Plasmodium falciparum, Plasmodium ovale and Plasmodium malariae. (ox.ac.uk)
Plasmodium vivax is the most widely distributed form of malaria in the world and it can be present not only in Africa but also in the Western Pacific, and importantly in highly populated areas of Latin America and Asia, where it is a big problem. (ox.ac.uk)
After different attempts for elimination only Plasmodium falciparum could be eliminated but vivax remained, and this is because it forms this kind of structure but falciparum does not. (ox.ac.uk)
Vivax vaccine development is in the early stages of development in comparison to Plasmodium falciparum which is more advanced. (ox.ac.uk)
The main species causing AAT in cattle are T. congolense, T. vivax, and T. b. brucei. (kab.ac.ug)
These bloodstream forms develop and multiply within the fly and then migrate to the mouthparts ( T. vivax and T. congolense ) or the salivary glands ( T. brucei ). (tsetse.org)
This process takes 5-13 days for Trypanosoma vivax , 15-23 days for T. congolense and 12-23 days for T. brucei. (tsetse.org)
Infection rates in tsetse populations are generally low, ranging from about 5% for T. vivax and T. congolense to less than 1% for T. brucei. (tsetse.org)
Brucei1
OBJECTIVES The study was to investigate the effects of Allium sativum extract on Trypanosoma brucei brucei parasites' morphometric parameters, parasitemia and the clinical outcome in white infected Albino laboratory rats in order to determine its trypanocidal effects. (bvsalud.org)
Infection4
Studies on effects of lactose on experimental Trypanosoma vivax infection in Zebu cattle. (ojvr.org)
Molecular Diagnosis of Subclinical African Trypanosoma Vivax Infection and Association with Physiological Indices and Serum Metabolites in Extensively Managed Goats in the Tropics. (rit.edu)
The PCR revealed T. vivax DNA in 7/56 semen samples of post-infection T01 cattle. (bvsalud.org)
Trypanosoma vivax infection in Sudanese cattle in central Sudan. (livedna.net)
Evansi2
Sequencing of the ITS1 region of the Trypanosoma species detected herein revealed that camels were infected with T. evansi and T. simiae. (researchgate.net)
Conclusions: Trypanosoma evansi is highly prevalent in camels from the Banadir region of Somalia, particularly in nomadic herds. (researchgate.net)
Prevalence1
Considering the lack of state-of-the-art knowledge on camel trypanosomiasis in Somalia, the present study aimed to assess the prevalence of Trypanosoma spp. (researchgate.net)
Cattle7
Trypanosoma vivax is a significant drag on Africa's cattle production every year, and increasingly is a concern in South America: One outbreak in 1995 in the Pantanal in Brazil and Bolivia cost the industry over US$160 million. (wikipedia.org)
The present work investigated the presence of Trypanosoma vivax in semen and reproductive tissues of experimentally infected cattle and evaluated changes in seminal parameters. (bvsalud.org)
Two groups of cattle were established: T01 - experimentally infected with T. vivax (n = 8) and T02 - not experimentally infected with T. vivax (n = 8). (bvsalud.org)
The results highlight the presence of T. vivax DNA in semen of infected cattle and the importance of this disease for male breeding cattle. (bvsalud.org)
Further research is needed to determine whether T. vivax can be sexually transmitted in cattle. (bvsalud.org)
The present study evaluated the efficacy of enrofloxacin (7.5 mg/kg) against A. marginale in naturally infected cattle and cattle experimentally co-infected with T. vivax by observation of the variation in A. marginale parasitemia and packed cell volume (PCV) for 39 days. (bvsalud.org)
Trypanosoma vivax causes bovine trypanosomosis in cattle and resulting in economic losses to farmers. (bvsalud.org)
P. vivax is difficult to eradicate since the parasite can evolve into a hypnozoite, a small structure that can hide dormant in the liver of an infected person for a long time. (ox.ac.uk)
Leishmania1
The major human parasites include a number of species in the genera Leishmania and Trypanosoma . (biomedcentral.com)
Trypanosome3
Unusual for a trypanosome, T. vivax does not infect the Glossina vector midgut. (wikipedia.org)
Previous studies on detection of Trypanosoma species in Somali camels have only been performed during the 1990s using standard trypanosome detection methods (STDM). (researchgate.net)
This question is of more than theoretical interest because Trypanosoma includes both African and American trypanosome parasites of humans. (biomedcentral.com)
Malaria1
There is in vivo evidence for the P. vivax resistance to CQ in the Brazilian Amazon, where the increase in the proportion of P. vivax malaria parallels the increase of unusual clinical complications related to this species. (unl.pt)
Species1
In particular, we address the issue of the relationship between American and African trypanosomes and whether or not the genus Trypanosoma , as currently recognized, represents a clade or monophyletic group (i.e., whether Trypanosoma includes all the descendants of a single ancestral species and only the descendants of that ancestral species). (biomedcentral.com)
Genus2
Using a variety of phylogenetic methods, 18S rRNA phylogenies indicate that the genus Trypanosoma is not monophyletic. (biomedcentral.com)
By contrast, phylogenetic analyses of available sequences in 42 protein families gene generally supported monophyly of the genus Trypanosoma . (biomedcentral.com)
Evolution and diagnostic utility of major surface proteases from trypanosoma vivax, t. (ac.ke)
Vitro2
To evaluate the effectiveness of different disinfectants for T. vivax, in vitro and in vivo analyses were performed. (bvsalud.org)
In this study, in vitro CQ and mefloquine (MQ)-susceptibility of P. vivax isolates from the Western Brazilian Amazon was tested using the double-site enzyme-linked lactate dehydrogenase immunodetection (DELI) assay. (unl.pt)
Transmission of South American Trypanosoma vivax by the neotropical hosefly Tabanus nebulosus. (envycare.ca)
Parasitemia1
In conclusion, bovines co-infected T. vivax needed four more treatments with enrofloxacin to reduce A. marginale parasitemia and keep PCV values within reference standards. (bvsalud.org)
Animals2
Trypanosoma vivax DNA was detected in the semen of 5/8 animals at 7, 14, 56, 70 and 120 DPI, in the testis of four, and in the epididymis and fat located around the testis of two others. (bvsalud.org)
T02 = animals immunosuppressed with dexamethasone, with latent anaplasmosis and experimentally co-infected with T. vivax on day 0 (D0). (bvsalud.org)
The smallest variable surface glycoprotein (40 kDa in size) to date has been found in T. vivax, which bears little carbohydrate. (wikipedia.org)
Trypomastigote forms of T. vivax were not found in any semen sample. (bvsalud.org)
Negative1
Thirty calves negative for T. vivax were divided into six groups and were inoculated with disinfectant solutions (46% alcohol, 70% alcohol, or 0.5% iodine) + 1 × 106 trypomastigotes of the protozoa. (bvsalud.org)
Importance1
A novel proline racemase of medical and veterinary importance has been described in T. vivax (B8LFE4). (wikipedia.org)
Gambiense3
His Trypanosoma brucei gambiense and Trypanosoma vivax study, which is part of a larger body of work in Trypanosomiasis, is frequently linked to Infection rate, bridging the gap between disciplines. (research.com)
during 2010 and 2011, the notification capability of the GeoSentinel network was used in the identification and public health response to East African trypanosomiasis in Eastern Zambia and North Central Zimbabwe, P. vivax malaria in Greece, and muscular sarcocystosis on Tioman Island, Malaysia. (cdc.gov)
His research investigates the connection between African trypanosomiasis and topics such as Glossina palpalis that intersect with problems in Entomology, Virology, Trypanosoma vivax and 16S ribosomal RNA. (research.com)
Recombinant and native tvi catl from trypanosoma vivax cape girardeau : enzymatic characterisation pampa and evaluation as a diagnostic target for animal african trypanosomosis. (dakne.co)
Tsetse2
Trypanosoma vivax infections in one of the areas surveyed became more prevalent as distance from the tsetse-belt increased. (gla.ac.uk)
His Wigglesworthia research integrates issues from Tsetse fly and Trypanosoma. (research.com)
Goats4
This study aimed to identify the presence of Trypanosoma vivax DNA in the colostrum of infected goats and to explore the possibility of transmission for neonates fed using colostrum collected from infected goats. (pvb.org.br)
Six goats were inoculated intravenously with 0.5mL of blood containing approximately 1.25x105 trypomastigotes of T. vivax, and six remained uninfected. (pvb.org.br)
The possibility of T. vivax transmission by colostrum was assessed by feeding six neonates born of serologically negative goats using colostrum from infected goats. (pvb.org.br)
The results of a direct examination of colostrum were negative, but PCR confirmed the presence of T. vivax DNA in all infected goats. (pvb.org.br)
Glossina1
Unusual for a trypanosome, T. vivax does not infect the Glossina vector midgut. (wikipedia.org)
A novel proline racemase of medical and veterinary importance has been described in T. vivax (B8LFE4). (wikipedia.org)
Protein1
The Trypanosoma brucei FKBP12 homologue (TbFKBP12) was found to be a cytoskeleton-associated protein with specific localization in the flagellar pocket area of the bloodstream form. (pasteur.fr)
Smears1
Peripheral blood from neonates was collected daily for thirty days to assess the T. vivax presence through the examination of Giemsa-stained smears of leukocyte layers with the buffy coat technique (BCT) and by PCR. (pvb.org.br)