IIIAZinc fingerInteractsProteinsProteinGenesCharacterizationTranscriptionalBoundGene transcriptionInitiationSequenceRRNALiteratureComplexStressMuscleProteinsRibosomalTFIIIB and TFIIICPolymeraseYeast transcriptionRegulateSubunitsSequencesHeterochromatinTRNAInhibitionPathwaysHumanCellularSpecificRegulationRecognitionActivationDomains
IIIA6
- cDNA cloning, DNA binding, and evolution of mammalian transcription factor IIIA. (curehunter.com)
- Transcription factor IIIA is a protein that in humans is encoded by the GTF3A gene. (wikipedia.org)
- Amphibian transcription factor IIIA proteins contain a sequence element functionally equivalent to the nuclear export signal of human immunodeficiency virus type 1 Rev". Proceedings of the National Academy of Sciences of the United States of America. (wikipedia.org)
- The levels of CBCVd in tobacco were enhanced in plant hybrids expressing CBCVd cDNAs and either the tobacco or hop variant of TFIIIA-7ZF, a viroid-mediated splicing derivative of transcription factor IIIA, which is important for viroid replication by DNA-dependent RNA polymerase II. (bvsalud.org)
- Xenopus transcription factor IIIA binds to the flanking regions of the 5 S RNA gene intragenic control region in a unique and highly ordered state. (xenbase.org)
- The interaction of Xenopus transcription factor IIIA (TFIIIA) with the intragenic control region (ICR) of the 5 S RNA gene was studied by footprinting techniques under conditions which elicited a unique DNase I digestion pattern. (xenbase.org)
Zinc finger4
- The TFIIIA in Xenopus was the first zinc finger protein discovered. (wikipedia.org)
- To obtain structural information, we synthesized single and double zinc finger peptides from the yeast transcription activator ADR1, and assessed the metal-binding and DNA-binding properties of these peptides, as well as the solution structure of the metal-stabilized domains, with the use of a variety of spectroscopic techniques. (embl.de)
- Zinc finger proteins constitute a large family of transcription factors and numerous members of them play diverse roles in many biological processes, including plant growth, development and stress responses. (nefu.edu.cn)
- 5. Kielbowicz-Matuk A. Involvement of plant C 2 H 2 -type zinc finger transcription factors in stress responses[J].Plant Sci,2012,185-186:78-85. (nefu.edu.cn)
Interacts2
- Gene-specific factor TFIIIA interacts with DNA and acts as an adaptor for TFIIIC-promoter interactions. (bvsalud.org)
- A nucleation site, most likely at or near the ICR, is proposed to exist through which TFIIIA specifically interacts and orients the binding of additional protein molecules in a cooperative and highly ordered manner to the flanking DNA sequences on either side of the ICR. (xenbase.org)
Proteins2
- These transcription factors work by regulating different mechanisms of drought tolerance and by releasing hormones, proteins, reducing-sugars, solutes and by affecting the stomatal conductance and root architecture. (org.pk)
- In mice, rapamycin treatment increases expression of histone proteins and Wdfy3 transcription, and alters chromatin organisation in the small intestine, suggesting the mTORC1-histone axis is at least partially conserved in mammals and may offer new targets for anti-ageing interventions. (sdbonline.org)
Protein1
- 3. Miller J,McLachlan A D,Klug A. Repetitive zinc-binding domains in the protein transcription factor Ⅲ A from Xenopus oocytes [J].EMBO J,1985,4(6):1609-1614. (nefu.edu.cn)
Genes1
- Identification of different stress responsive genes and transcriptional factors especially WRKY TFs have provided platform to obtain good crop stand and yield even under stress conditions. (org.pk)
Characterization1
- Characterization of a transcription factor involved in mother cell specific transcription of the yeast HO gene. (ox.ac.uk)
Transcriptional2
- A region of the HO promoter involved in the SWI5-dependent transcriptional activation of HO was identified by deletion analysis of the HO promoter in the chromosome, and by testing the ability of HO DNA fragments to activate transcription in the context of a heterologous promoter. (ox.ac.uk)
- 2. Golldack D,Lüking I,Yang O. Plant tolerance to drought and salinity:stress regulating transcription factors and their functional significance in the cellular transcriptional network[J].Plant Cell Rep,2011,30(8):1383-1391. (nefu.edu.cn)
Bound1
- Here, we use cryoelectron microscopy (cryo-EM) to visualize the S. cerevisiae complex of TFIIIA and TFIIIC bound to the promoter. (bvsalud.org)
Gene transcription1
- The APP effect near the ICR may play a role in the initiation and stabilization of 5 S RNA gene transcription. (xenbase.org)
Initiation1
- Our findings provide new insights into the transcription initiation complex assembly on the 5S rRNA promoter and allow us to directly compare Pol III and Pol II transcription adaptations. (bvsalud.org)
Sequence1
- The predicted amino acid sequence derived from the cloned SWI5 gene shows homology with the repeated DNA-binding domains ('zinc fingers') of Xenopus transcription factor TFIIIA. (ox.ac.uk)
RRNA1
- Its recruitment to the 5S rRNA promoter requires transcription factors TFIIIA, TFIIIC, and TFIIIB. (bvsalud.org)
Literature1
- The subunit complex plays estimated by inhibitors at the regulatory primary kidney( transporter) and the cleavage is the project literature by capability of its transcription return, which is been during manner to contribute NOTCH1. (familie-vos.de)
Complex2
- The complex transcription is converted through the cerebellar localization into the t. sterically in the synthesis, the 10e6 diversity mature RNA( vRNA) is reviewed into stature RNA( mRNA) by a Ser1177 cancer. (evakoch.com)
- ions are as composed in the caveolin of triple integrin factor through FAK which is the SLC27 family to fat effect CSNK1E and offer non deformed activity complex( Shi et al. (familie-vos.de)
Stress1
- 1. Singh K,Foley R C,Onate-Sanchez L. Transcription factors in plant defense and stress responses[J].Curr Opin Plant Biol. (nefu.edu.cn)
Muscle2
- Control of muscle differentiation in BC3H1 cells by fibroblast growth factor and vanadate. (wustl.edu)
- The diarrhoea muscle is 5 factors( expressed 0-4). (familie-vos.de)
Proteins3
- 15. Requirement of Nhp6 proteins for transcription of a subset of tRNA genes and heterochromatin barrier function in Saccharomyces cerevisiae. (nih.gov)
- PLATZ proteins are a novel class of plant-specific zinc-dependent DNA-binding proteins that are classified as transcription factors (TFs). (biomedcentral.com)
- These findings indicate that ZmPLATZ proteins are generally involved in the modulation of RNAPIII-mediated small non-coding RNA transcription. (biomedcentral.com)
Ribosomal2
TFIIIB and TFIIIC2
- 1. Distinct roles of transcription factors TFIIIB and TFIIIC in RNA polymerase III transcription reinitiation. (nih.gov)
- In yeast, the RNAPIII transcription complex requires three transcription factors in addition to Pol III: two general transcription factors, TFIIIB and TFIIIC, and a specific transcription factor, TFIIIA, which is only required for the synthesis of 5S rRNA [ 14 ]. (biomedcentral.com)
Polymerase8
- 4. The transcription reinitiation properties of RNA polymerase III in the absence of transcription factors. (nih.gov)
- 6. Function of TFIIIC, RNA polymerase III initiation factor, in activation and repression of tRNA gene transcription. (nih.gov)
- 12. p53 represses RNA polymerase III transcription by targeting TBP and inhibiting promoter occupancy by TFIIIB. (nih.gov)
- 14. S. cerevisiae TFIIIB is the transcription initiation factor proper of RNA polymerase III, while TFIIIA and TFIIIC are assembly factors. (nih.gov)
- 17. Inhibition of RNA polymerase III transcription by BRCA1. (nih.gov)
- 20. Nhp6 is a transcriptional initiation fidelity factor for RNA polymerase III transcription in vitro and in vivo. (nih.gov)
- One of several general transcription factors that are specific for RNA POLYMERASE III . (nih.gov)
- Our recent work shows that FL3 (ZmPLATZ12) interacts with RPC53 and TFC1, two critical factors in the RNA polymerase III (RNAPIII) transcription complex. (biomedcentral.com)
Yeast transcription1
- To obtain structural information, we synthesized single and double zinc finger peptides from the yeast transcription activator ADR1, and assessed the metal-binding and DNA-binding properties of these peptides, as well as the solution structure of the metal-stabilized domains, with the use of a variety of spectroscopic techniques. (embl.de)
Regulate3
- Different histone variants can contribute to distinct or unique nucleosomal architectures, which could potentially be exploited to regulate nuclear functions such as transcription, gene silencing, replication or recombination. (biomedcentral.com)
- Transcription factor p53 forms a network with associated factors to regulate the cell cycle and apoptosis in response to environmental stresses. (shengsci.com)
- These results suggest that Rib and Lola act as dual-function transcription factors to cooperatively regulate embryonic gonad morphogenesis. (sdbonline.org)
Subunits1
- 11. The Brf1 and Bdp1 subunits of transcription factor TFIIIB bind to overlapping sites in the tetratricopeptide repeats of Tfc4. (nih.gov)
Sequences2
- The first reported member was PLATZ1, which was isolated from pea ( Pisum sativum ) [ 10 ] and shown to bind nonspecifically to A/T-rich sequences and repress transcription. (biomedcentral.com)
- Cytosine methylation of mitochondrial DNA at CpG sequences impacts transcription factor A DNA binding and transcription. (ucdenver.edu)
Heterochromatin3
- The heterochromatin-like structure formed by the yeast silent information regulator complex (SIR) represses transcription at the silent mating type loci and telomeres. (shengsci.com)
- A role for MED14 and UVH6 in heterochromatin transcription upon destabilization of silencing. (igred.fr)
- Changes in 5S rDNA chromatin organization and transcription during heterochromatin establishment in Arabidopsis. (igred.fr)
TRNA1
- Understanding the sequence specificity of tRNA binding to elongation factor Tu using tRNA mutagenesis. (colorado.edu)
Inhibition1
- Our data demonstrate that, while induction of expression of p53 and/or its isoforms is crucial to suppress abnormal cell growth, Delta113p53 is tightly regulated by an organ/tissue-specific factor Def, especially during organogenesis, to prevent adverse inhibition of organ/tissue growth. (shengsci.com)
Pathways2
- Remarkably, not only did the data reveal the possible critical check points in the flavonoid, caffeine, and theanine biosynthesis pathways, but also implicated the key transcription factors and related mechanisms in the regulation of secondary metabolite biosynthesis. (biomedcentral.com)
- Among these factors, the second messengers, cAMP and cGMP, are known to be involved in establishing the guidance cues for axon growth through different intracellular signaling pathways. (sdbonline.org)
Human1
- Structural analysis and DNA binding of the HMG domains of the human mitochondrial transcription factor A. (ucdenver.edu)
Cellular1
- The enzyme telomerase, which elongates chromosome termini, is a critical factor in determining long-term cellular proliferation and tissue renewal. (shengsci.com)
Specific2
- Here we present evidence to show that the zebrafish def (digestive-organ expansion factor) gene encodes a novel pan-endoderm-specific factor. (shengsci.com)
- This enabled study of specific isoforms with respect to previously characterized roles for Lola and to demonstrate a specific function for one variant in axon guidance via activation of the microtubule-associated factor Futsch . (sdbonline.org)
Regulation1
- The possible transcription factor regulation network for the biosynthesis of flavonoid, caffeine, and theanine was built, encompassing 339 transcription factors from 35 families, namely bHLH, MYB, and NAC, among others. (biomedcentral.com)
Recognition1
- Correct pathfinding and target recognition of a developing axon are exquisitely regulated processes that require multiple guidance factors. (sdbonline.org)
Activation1
- Stress-induced activation of heterochromatic transcription. (igred.fr)
Domains1
- Artificial transcription factors (ATFs) are composed of DNA-binding and functional domains. (biomedcentral.com)