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  • adhesive
  • The phenomenon of adhesion occurs in welding, soldering, tin-plating, adhesive bonding, fabrication of photographic materials, and application of polymeric paints, coats, and varnishes to protect metal parts from corrosion. (thefreedictionary.com)
  • cell
  • Nectin-like molecule-1/TSLL1/SynCAM3: a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule localizing at non-junctional contact sites of presynaptic nerve terminals, axons and glia cell processes. (uniprot.org)
  • Nectins are Ca2+-independent immunoglobulin-like cell-cell adhesion molecules and comprise a family of four members. (uniprot.org)
  • Necl-1 showed Ca2+-independent homophilic cell-cell adhesion activity. (uniprot.org)
  • It furthermore showed Ca2+-independent heterophilic cell-cell adhesion activity with Necl-2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 from now on referred to as Necl-2, nectin-1 and nectin-3, but not with Necl-5 or nectin-2. (uniprot.org)
  • These results indicate that Necl-1 is a neural-tissue-specific Ca2+-independent immunoglobulin-like cell-cell adhesion molecule which potentially has membrane-associated guanylate kinase subfamily member-binding activity and localizes at the non-junctional cell-cell contact sites. (uniprot.org)
  • It exhibits robust focal adhesion localization in several cultured cell types but is not found along the length of the associated actin-rich stress fibers. (rupress.org)
  • Together, these results suggest an important role for actopaxin in integrin-dependent remodeling of the actin cytoskeleton during cell motility and cell adhesion. (rupress.org)
  • Cell adhesion and migration are integral components of many biological processes including normal development and recovery from injury and infection. (rupress.org)
  • Some focal adhesion proteins such as vinculin, talin, and α-actinin function solely to provide a structural link between integrins and F-actin, whereas others such as the focal adhesion kinase (FAK), Cas, and paxillin function as scaffold proteins and are involved in coordinating integrin-mediated signal transduction ( Burridge and Chrzanowska-Wodnicka 1996 ) associated with the regulation of cell motility, gene expression, and cell proliferation ( Giancotti and Ruoslahti 1999 ). (rupress.org)
  • surface
  • Firm adhesion is also achieved when a new solid phase forms on the interface-for example, in electroplating or in the case of surface-active chemical compounds (oxide films, sulfide films, and so forth). (thefreedictionary.com)
  • organs
  • Acting like powerful straight jackets, adhesions can squeeze nerves, organs and joints - causing internal pain or dysfunction including female infertility and life-threatening bowel obstructions . (clearpassage.com)
  • While a person may first feel the pain only at the hip or tailbone, adhesions can slowly spread to bind nearby organs such as the bowel, bladder, fallopian tubes or ovaries. (clearpassage.com)
  • They may become painful and inhibit proper function by adhering tissues and organs that are designed to move freely. (clearpassage.com)
  • In medicine, the term soft tissue refers to tissues that connect, support, or surround other structures and organs of the body. (phys.org)
  • In neural crest cells, which are transient cells that arise in the developing organism during gastrulation and function in the patterning of the vertebrate body plan, the cadherins are necessary to allow migration of cells to form tissues or organs. (wikipedia.org)
  • Another source of pain is the organ dislocation that arises from adhesion binding internal organs to each other. (wikipedia.org)
  • vagina
  • Adhesions involving the vagina or uterus may cause pain during intercourse . (emedicinehealth.com)
  • Vaginal rejuvenation: A "vaginal rejuvenation" is a non-reconstructive vaginoplasty that restores the muscle tone and desired aesthetic of the vagina, by removing external tissues and tightening the supportive structures of the vulvovaginal complex, in an effort either to reduce or to reverse the effects of aging and parturition (childbearing). (wikipedia.org)
  • ovaries
  • Conservative surgery can be performed to preserve fertility in younger patients but as earlier stated can have the effect of raising FSH values and making the ovaries less productive, especially if functional ovarian tissue is removed in the surgical process. (wikipedia.org)
  • tumors
  • In tumors such as ovarian cancer, in which cellular adhesion to the matrix plays a critical role in the establishment of metastases ( 8 ), such inhibitors may prevent cancer dissemination. (aacrjournals.org)
  • Developing tissues change shape and tumors initiate spreading through collective cell motility. (rupress.org)
  • Neoplasia is the medical term used for both benign and malignant tumors, and is used as a blanket term that refers to abnormal, excessive, uncoordinated, and autonomous cellular/tissue growth. (wikipedia.org)
  • Ultrasound can ablate tumors or other tissue non-invasively. (wikipedia.org)
  • neural
  • Nectin-like molecule-1/TSLL1/SynCAM3: a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule localizing at non-junctional contact sites of presynaptic nerve terminals, axons and glia cell processes. (uniprot.org)
  • Tissue distribution analysis showed that Necl-1 was specifically expressed in the neural tissue. (uniprot.org)
  • These results indicate that Necl-1 is a neural-tissue-specific Ca2+-independent immunoglobulin-like cell-cell adhesion molecule which potentially has membrane-associated guanylate kinase subfamily member-binding activity and localizes at the non-junctional cell-cell contact sites. (uniprot.org)
  • For example, during neurulation, when the neural plate is forming in the embryo, the tissues residing near the cranial neural folds have decreased N-cadherin expression. (wikipedia.org)
  • hemostats
  • The global surgical hemostats, internal tissue sealants and adhesion barriers market is set to cross US$ 5 Billion by 2024, expanding at a CAGR of over 8% during the next eight years. (medgadget.com)
  • Moreover, increasing focus on developing advanced surgical sealants and adhesion barriers owing to the inadequacy of hemostatic products such as oxidized regenerated cellulose based and gelatin based hemostats that are eventually reaching limitation. (medgadget.com)
  • structures
  • Like tiny but powerful straight jackets, adhesions can join structures from different bodily systems with strong glue-like bonds that can last a lifetime. (clearpassage.com)
  • An outstanding question is how tissues transition from compact structures dominated by cell-cell adhesions to invading cohorts of cells that interact extensively with their ECMs. (rupress.org)
  • Other tissue interactions that DAH offers an explanation for includes tissue hierarchy, where tissues with weaker surface adhesion surround tissues with stronger surface adhesion, the rounding of irregular cell masses to become spherical, and the cell sorting and construction of anatomical structures that occurs independent of the path taken. (wikipedia.org)
  • Morphogenesis
  • In many cases, branching morphogenesis is initiated when growth factors stimulate a few individual cells within the developing tissue to extend protrusions that adhere to the surrounding ECM. (rupress.org)
  • Developing axons often grow over BM substrates, and BM components play central roles both in tissue morphogenesis and in axon guidance ( Hinck, 2004 ). (biologists.org)
  • Yet, rather than a passive scaffold for tissue morphogenesis, the ECM can be regarded as an active participant in tissue morphogenesis and cell signaling ( Nelson and Bissell, 2006 ). (biologists.org)
  • Differential adhesion hypothesis (DAH) is a hypothesis that explains cellular movement during morphogenesis with thermodynamic principles. (wikipedia.org)
  • barriers
  • On the basis of product, the biosurgery is broadly segmented into bone-graft substitutes, soft-tissue attachments, hemostatic agents, surgical sealants and adhesives, adhesion barriers, and staple-line reinforcement agents. (marketresearch.com)
  • proteins
  • Many proteins involved in these adhesions serve both mechanical and signaling roles. (nih.gov)
  • Tissue transglutaminase (TG2) is an enzyme involved in Ca 2+ -dependent aggregation of proteins by facilitating formation of ε-(γ-glutamyl)lysine isopeptide bonds in cross-linked proteins. (aacrjournals.org)
  • soft tissue
  • For that reason, nearly all study of dinosaur soft tissue has to be reconstructed from fossil bones. (phys.org)
  • There is little evidence that active ultrasound is more effective than placebo treatment for treating patients with pain or a range of musculoskeletal injuries, or for promoting soft tissue healing. (wikipedia.org)
  • Effectiveness of therapeutic ultrasound for pain, musculoskeletal injuries, and soft tissue lesions remains questionable. (wikipedia.org)
  • Maximum energy absorption in soft tissue occurs from 2 to 5 cm. (wikipedia.org)
  • differential
  • Direct binding of compounds that inhibited adhesion to TG2 were examined with differential scanning fluorimetry, which measures the effect of the compound on the melting temperature of the target. (aacrjournals.org)
  • infertility
  • AFS (= American Fertility Society) score was developed in 1980's by the American Fertility Society in an effort to address needs for a classification scheme for adnexal adhesions suspected to be associated with infertility. (clinicaltrials.gov)
  • reaction
  • To assess the relative contribution of adhesion molecules, including selectins and ICAM-1, in this pathogenetic process, the cutaneous passive Arthus reaction was examined in mice lacking E-selectin, P-selectin, or both L-selectin and ICAM-1 with anti-P-or E-selectin mAbs. (nii.ac.jp)
  • The second reaction is an aseptic fibrinous response, resulting in tissue adhesions and encapsulation and eventually foreign body granuloma. (wikipedia.org)
  • The stromal reaction in cancer is similar to the stromal reaction induced by injury or wound repair: increased ECM and growth factor production and secretion, which consequently cause growth of the tissue. (wikipedia.org)
  • woman's
  • A perineoplasty procedure repairs damage to the perineum and damage to the Vulva that a woman might experience as a result of: Child birth - the stretching of parturition can cause tears to the tissues, or might require cutting (episiotomy) should the woman's birth canal prove too narrow to allow unobstructed passage of the infant. (wikipedia.org)
  • anatomic
  • Moreover, any perineal tissue that presents either a cut or a tear can heal and fuse together before the stitches dissolve, regardless of whether or not the tissues originally were joined in that anatomic configuration. (wikipedia.org)
  • Elastic
  • Relatively high power ultrasound can break up stony deposits or tissue, accelerate the effect of drugs in a targeted area, assist in the measurement of the elastic properties of tissue, and can be used to sort cells or small particles for research. (wikipedia.org)
  • clitoral
  • Another technique cuts away (excises) the redundant folds of clitoral prepuce tissue, with incisions parallel to the long axis of the clitoris. (wikipedia.org)
  • Clitoral hood reduction can be included in the extended wedge resection labiaplasty technique, wherein the extension of the exterior wedge sections is applied to reducing the prepuce tissues of the clitoral glans. (wikipedia.org)
  • The clitoral hood is also important not only in protection of the clitoral glans, but also in pleasure, as it is an erogenous tissue. (wikipedia.org)
  • mechanical
  • We review the biophysical principles and experimental tools used to study adhesion so that we may aid efforts to understand how adhesions guide these movements and integrate their signaling functions with mechanical function. (nih.gov)
  • This 'pull' often creates mechanical irritation, generating more adhesion formation. (clearpassage.com)
  • waves
  • These adhesions trigger waves of cramp-like pain in the stomach. (emedicinehealth.com)
  • Ultrasound is a method of stimulating the tissue beneath the skin's surface using very high frequency sound waves, between 800,000 Hz and 2,000,000 Hz, which cannot be heard by humans. (wikipedia.org)