• Thyrotropin releasing hormone stimulation showed blunt response of TSH but good response for prolactin. (medassocthai.org)
  • Thyrotropin-releasing hormone receptor activation in the spinal cord increases blood pressure and sympathetic tone to the vasculature and the adrenals. (aspetjournals.org)
  • Identification of the Thyrotropin-Releasing Hormone (TRH) as a Novel Biomarker in the Prognosis for Acute Myeloid Leukemia. (nih.gov)
  • This gene encodes a member of the thyrotropin-releasing hormone family. (nih.gov)
  • Thyrotropin-releasing hormone (TRH) activates not merely the secretion of thyrotropin (TSH) but also the transcription of TSHβ and α-glycoprotein (αGSU) subunit genes. (bioerc-iend.org)
  • Secretion of the TSH LM22A-4 molecule from thyrotroph and the transcriptions of TSHβ and αGSU genes are stimulated by the thyrotropin-releasing hormone (TRH) generated in the hypothalamic paraventricular nucleus. (bioerc-iend.org)
  • In Xenopus oocytes injected with total rat pituitary GH 3 cell RNA, thyrotropin‐releasing hormone (TRH) causes the activation of the inositol lipid transduction pathway and the induction of chloride conductance via calcium‐activated channels (Oron et al. (tau.ac.il)
  • The effects of dieting and weight loss upon the stimulation of thyrotropin (TSH) by thyrotropin-releasing hormone (TRH) and suppression of cortisol secretion by dexamethasone in men and women. (ox.ac.uk)
  • Thyrotropin-releasing hormone (TRH) receptor number determines the size of the TRH-responsive phosphoinositide pool. (cornell.edu)
  • The thyrotropin-releasing hormone (TRH) analog taltirelin is of high pre-clinical interest given its neuronal-stimulant properties, minimal endocrine activity, tongue muscle activation following microperfusion into the hypoglossal motor nucleus (HMN) or systemic delivery, and high TRH receptor expression at the HMN compared to rest of the brain. (nature.com)
  • Examples of such peptides include neurotensin, luteinizing hormone releasing hormone, and thyrotropin-releasing hormone. (novusbio.com)
  • Long-term efficacy of modified-release recombinant human thyrotropin augmented radioiodine therapy for benign multinodular goiter: results from a multicenter, international, randomized, placebo-controlled, dose-selection study. (harvard.edu)
  • In the present study we examined the clinical value of a differential response of thyroglobulin (Tg) concentration after recombinant human thyrotropin (rhTSH) stimulation (rhTSH Tg testing) and its correlation with (131)I uptake and whole-body scanning (rhTSH-WBS) in 104 patients who had previously undergone near-total thyroidectomy and (131)I ablation for differentiated thyroid carcinoma (DTC). (unife.it)
  • These autoantibodies, also known as long-acting-thyroid-stimulator (LATS) or thyroid-stimulating immunoglobulins (TSI), bind to the receptor and transactivate it, leading to stimulation of the thyroid gland independent of the normal feedback-regulated thyrotropin (TSH) stimulation. (marshfieldlabs.org)
  • The thyrotropin receptor (or TSH receptor) is a receptor (and associated protein) that responds to thyroid-stimulating hormone (also known as "thyrotropin") and stimulates the production of thyroxine (T4) and triiodothyronine (T3). (wikipedia.org)
  • Aims Understanding the exact relationship between serum thyrotropin/thyroid stimulating hormone (TSH) and free thyroxine (FT 4 ) is a prerequisite for improving diagnostic reliability and clinical decision making. (bmj.com)
  • It has been suggested that the thyrotropin (thyroid stimulating hormone (TSH)) stimulution test may be helpful in confirming a diagnosis of feline hyperthyroidism when the serum total thyroxine (T4) concentration is equivocal. (avmi.net)
  • Thyrotropin Alfa" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
  • The amino acid sequence of thyrotropin alfa is identical to that of human pituitary thyroid stimulating hormone. (harvard.edu)
  • This graph shows the total number of publications written about "Thyrotropin Alfa" by people in Harvard Catalyst Profiles by year, and whether "Thyrotropin Alfa" was a major or minor topic of these publication. (harvard.edu)
  • Below are the most recent publications written about "Thyrotropin Alfa" by people in Profiles. (harvard.edu)
  • In TED patients, these cells express a higher level of thyrotropin receptor (TSHR) and insulin-like growth factor-1 receptor than ordinary fibroblasts [ 3 ]. (ekjo.org)
  • Graves' disease is an autoimmune disease mediated by autoantibodies to the thyrotropin receptor (TSHR). (utmb.edu)
  • Autoimmune thyroid disease is characterized by the presence of autoantibodies against various thyroid components, namely the thyrotropin receptor, thyroid peroxidase, and thyroglobulin, as well as by an inflammatory cellular infiltrate of variable severity within the gland. (marshfieldlabs.org)
  • Thyrotropin-secreting pituitary adenomas: a systematic review and meta-analysis of postoperative outcomes and management. (unil.ch)
  • Tests to date, have shown Thyrotropin TRH (tripeptide hypothalamic regulatory hormone) is effective in regulating hormones concerned with the thyroid hormone. (usapeptides.info)
  • Effects of Thyrotropin on Peripheral Thyroid Hormone Metabolism and Serum Lipids. (harvard.edu)
  • Treatment for subclinical hyperthyroidism is recommended for patients who are at highest risk of osteoporosis and cardiovascular disease, including those older than 65 years or with persistent serum thyrotropin level less than 0.1 mIU/L. (medscape.com)
  • To determine the clinical and biochemical relationships between a second-generation thyrotropin receptor-binding inhibition antibody (TRAb) immunoassay, detecting stimulatory and blocking antibodies, with the thyroid stimulating immunoglobulin (TSI) bridging immunoassay detecting the stimulatory component only. (ekjo.org)
  • Clinical presentation, thyroid function tests, and thyrotropin-receptor antibody status are key in establishing etiology. (medscape.com)
  • Monoclonal antibodies to the thyrotropin receptor: stimulating and blocking antibodies derived from the lymphocytes of patients with Graves disease. (unipi.it)
  • This report characterizes four antibodies as presumptive thyrotropin receptor antibodies because they specifically inhibit thyrotropin binding and competitively inhibit thyrotropin-induced cAMP levels in human thyroid cells. (unipi.it)
  • These two antibodies do not react with human thyroid gangliosides but are strong inhibitors of thyrotropin binding to liposomes containing the high-affinity glycoprotein component from human, bovine, and rat thyroid membranes. (unipi.it)
  • their ability to inhibit thyrotropin-induced cAMP increases in thyroid cells competitively is complemented by more than additive agonism at low (10 pM) thyrotropin concentrations. (unipi.it)
  • The data unequivocally establish the pluritopic nature of the immunoglobulins in Graves disease and relate individual components or determinants of the thyrotropin receptor structure with specific autoimmune immunoglobulins. (unipi.it)
  • The first exon of the human thyrotropin-β (hTSHβ) gene has been demonstrated in our laboratory to contain a major thyroid hormone inhibitory element. (johnshopkins.edu)
  • in contrast, they are poor inhibitors of 125I-labeled thyrotropin binding to liposomes containing the glycoprotein component of the human thyrotropin receptor. (unipi.it)
  • Some patients with GD also have TRAb, which do not transactivate the thyrotropin receptor. (marshfieldlabs.org)
  • This report constitutes the first cloning and sequencing of the genes encoding the subunits of feline thyrotropin. (avmi.net)
  • By univariate and multivariate statistical methods we found delta TSH to be significantly influenced by the basal concentration of thyrotropin (TSH0) and the free thyroxin index (FT4I). (lu.se)
  • Who needs a thyrotropin test? (telesante.lt)
  • What sample is needed for the thyrotropin test? (telesante.lt)
  • Lower limit of normal Thyroid stimulating hormone (TSH or thyrotropin) test result referent values for adults is 0.3 (mlU/L). (lab-test-results.com)
  • The test most frequently ordered to test thyroid function is thyrotropin, commonly referred to as thyroid-stimulating hormone (TSH). (lab-test-results.com)
  • Thyrotropin Receptor Autoantibody Assessment in Thyroid Eye Disease: Does the Assay Type Matter? (ekjo.org)
  • There are two standard blood tests of thyroid function: the measurement of thyroid hormone, usually T4, and the measurement of thyrotropin (TSH). (cdc.gov)
  • We measured the thyrotropin response (delta TSH) to 200 micrograms of thyroliberin in 131 subjects without thyroid dysfunction or other disease and with basal values for thyroid function that were within the normal reference intervals for our laboratory. (lu.se)