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  • Lastly, all antibiotics can contribute to the development of diarrhea related to a Clostridium difficile ( C. diff ) infection , including tetracyclines. (clevelandclinic.org)
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  • Better choices may be available for the treatment of meibomianitis or acne rosacea in lactating women, especially since these conditions often require prolonged treatment, but I feel it is unwise to perpetuate the misconception that tetracyclines are always contraindicated during lactation. (aafp.org)
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  • Drug-resistant bacteria producing a resistance factor, TetA efflux pump (in red), during treatment with tetracycline antibiotic (in green). (axios.com)
  • Using technology with real-time viewing, a team of scientists say in Science Thursday they can now show how quickly E. coli becomes resistant to tetracycline - finding that bacteria can pass genes with resistance to each other and then use a pump to keep most of the antibiotic out for the 2 hours it takes to render the previously sensitive bacteria resistant to the drug. (axios.com)
  • The most surprising result was to observe that even in the presence of protein synthesis inhibitors (tetracycline antibiotic ), sensitive cells are still able to acquire the DNA, but more surprisingly they are still able to develop the resistance. (axios.com)
  • Concentrations of tetracycline in wastewater treatment plants is likely to select for bacterial resistance. (janusinfo.se)
  • The risk is clearly highest for lymecycline based on measured concentrations of tetracycline in uncleaned waste water that exceeds experimental established selective levels for antibiotic resistance in bacteria. (janusinfo.se)
  • Cross-resistance of these organisms to tetracyclines is common. (pediatriconcall.com)
  • SUMMARY: The isolation of Escherichia coli chromosomal mutants that increased, the level of resistance of a partially tetracycline-sensitive mutant of r 100-1 is described. (microbiologyresearch.org)
  • The level of intrinsic resistance to both chloramphenicol and tetracycline was increased about twofold. (microbiologyresearch.org)
  • Also, the levels of R factor-determined resistance to these drugs were increased by this host mutation and tetracycline resistance was expressed constitutively. (microbiologyresearch.org)
  • A cmlB mutant accumulated tetracycline at a threefold] lower rate than the wild-type strain, and it is proposed that the mutants have an altered permeability to the drugs and that this acts syner-gistically with the products of the R factor chloramphenicol and tetracycline resistance genes. (microbiologyresearch.org)
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  • Tetracycline was originally made from bacteria of the genus Streptomyces. (wikipedia.org)
  • Tetracyclines are a type of antibiotic that work on two major kinds of bacteria. (clevelandclinic.org)
  • Another use would be treating a feline condition known as a tetracycline responsive abscess in which draining abscesses are caused by L-form bacteria (a bacterial type that lacks a cell wall). (vin.com)
  • Tetracyclines are usually taken by mouth and work by preventing bacteria from producing proteins they need to grow and multiply. (msdmanuals.com)
  • you should know that when tetracycline is used during pregnancy or in babies or children up to age 8, it can cause the teeth to become permanently stained. (medlineplus.gov)
  • If tetracyclines are taken during that time, they may cause the unborn infant's teeth to become discolored and may slow down the growth of the infant's teeth and bones. (mayoclinic.org)
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  • Milk and other dairy products, antacids containing polyvalent cations, as well as various iron salts ingested simultaneously with tetracycline derivatives, might interfere with their absorption by 50 to 90% or even more. (nih.gov)
  • The pharmacokinetic interactions in absorption of tetracyclines likely to be clinically significant in cases where the infecting pathogens are moderately resistant to tetracyclines and relatively high serum concentrations are needed for proper bacteriostasis. (nih.gov)
  • Note that lymphcycline, which is recommended in the Wise list, is rapidly hydrolyzed to active tetracycline in conjunction with absorption. (janusinfo.se)
  • Tetracycline should not be given with food because food binds the drug and prevents its absorption into the body. (vin.com)
  • In their publication "Transfer of Drugs and Other Chemicals into Human Milk," the American Academy of Pediatrics places tetracycline under the label "Usually Compatible with Breast-Feeding," the classification used for those medications that are safest in lactation. (aafp.org)
  • Penicillin: May interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (pediatriconcall.com)
  • Demand for tetracycline has expanded, as it is one of the most effective and safe drugs required in the health system, according to the World Health Organization. (futuremarketinsights.com)
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  • As a result, there is a higher demand for pharmaceutical products and higher sales of tetracycline to maintain a healthy lifestyle and combat bacterial infections. (futuremarketinsights.com)
  • The tetracyclines are primarily bacteriostatic and are thought to exert their antimicrobial effect by the inhibition of protein synthesis. (pediatriconcall.com)
  • The tetracycline antibiotic family provides broad anti-bacterial protection by inhibiting bacterial protein synthesis. (vin.com)
  • In other words, tetracycline binds to bacterial protein-synthesis structures but not to mammalian ones. (vin.com)
  • Take tetracycline exactly as directed. (medlineplus.gov)
  • Take tetracycline 2 hours before or 4 hours after iron preparations and vitamin products that contain iron. (medlineplus.gov)
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  • For each isolates Minimum Inhibitory Concentrations (MIC) for Metronidazole (MTZ), Amoxicillin (AMX), Tetracycline (TC) and Ciprofloxacin (CIP) were determined by Epsilometer test. (scialert.net)
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  • The Actinobacteria genus Streptomyces produces the polyketide antibiotic tetracycline. (elisakits.co.uk)
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  • A study of lactating women who were taking 500 mg of tetracycline four times a day found that levels of tetracycline in the infants were below the level of detection (0.05 μg per mL). 2 , 3 Theoretic concerns about the possibility of dental staining or delayed bone growth in the infants seems unlikely at these serum concentrations. (aafp.org)
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  • Tetracyclines commonly have gastrointestinal side effects, like upset stomach and nausea. (clevelandclinic.org)
  • Some tetracyclines require you to take them on an empty stomach (without eating). (clevelandclinic.org)
  • Giving sucralfate (as might be used for stomach ulcers) should be staggered with tetracycline by a couple of hours. (vin.com)