• Sertoli
  • PFOS induces Sertoli cell injury using testicular cells isolated from rodent testes, but it remains unknown if PFOS has similar effects in humans. (popcouncil.org)
  • The expression of the Sertoli cell FGF2 gene required for SSC maintenance was significantly reduced in mutant testis. (fiu.edu)
  • genes
  • At ~80% confluency, they were used for studies including toxicant exposure, immunoblotting, immunofluorescence analysis, tight junction (TJ)-permeability assessment, and overexpression of BTB (blood-testis barrier) regulatory genes such as FAK and its phosphomimetic mutants. (popcouncil.org)
  • Based on these findings we propose that the deregulation of somatic and germ cell genes in the cryptorchid testis, directs the SSCs towards the differentiation pathway. (fiu.edu)
  • Head
  • The formation of cysts in the rete testis is associated with the obstruction of the efferent ducts, which connect the rete testis with the head of the epididymis. (wikipedia.org)
  • cells
  • The Fate of Spermatogonial Stem Cells in the Cryptorchid Testes of RXF" by Lydia Ferguson, Javier J. How et al. (fiu.edu)
  • In contrast, the expression of Plzf , a marker for undifferentiated and differentiating spermatogonia was not reduced, and the number of PLZF+ cells in the cryptorchid testis was higher in three month old testes, but equal to control in six month old mutants. (fiu.edu)
  • The PLZF+ cells did not show a higher rate of apoptosis in cryptorchid testis. (fiu.edu)
  • Ferguson L, How JJ, Agoulnik AI (2013) The Fate of Spermatogonial Stem Cells in the Cryptorchid Testes of RXFP2 Deficient Mice. (fiu.edu)
  • Small
  • Rete tubular ectasia is a benign condition, usually found in older men, involving numerous small, tubular cystic structures within the rete testis. (wikipedia.org)